Sociodemographic Factors and Clinical Profile of Covid-19 Patients Admitted in a Tertiary Care Centre of Central Rajasthan, India
BACKGROUNDCovid-2019, caused by severe acute respiratory syndrome-coronavirus-2 (SARSCoV2), is an ongoing pandemic that emerged from China in November 2019. Ithas affected millions of people worldwide causing significant morbidity andmortality. We wanted to analyse the clinical and demographic profile of Covid-19patients admitted in a tertiary-care-centre in the central part of Rajasthan,compare their characteristics with other studies published from parts of NorthernIndia and identify factors associated with delayed recovery and mortality.METHODSThis was a retrospective observational analysis of the clinical features, andepidemiological profile of Covid-19 positive patients admitted at a tertiary-carecentre in the Central part of Rajasthan.RESULTSA total of 422 patients was enrolled in the study. The male: female ratio was 1.34with a mean age of 34.1 years. Almost 195 (46.2 %) patients were in the agegroup of 20 - 40 years. Respiratory diseases were the most common co-morbidityseen in 36 patients (8.53 %), diabetes-mellitus in 28 patients (6.63 %),hypertension in 22 patients (5.2 %). Fever was the commonest presentingsymptom (N = 98, 77.17 %), followed by cough (N = 85, 66.93 %), andbreathlessness (N = 51, 45.67 %). Factors significantly associated with mortalitywere age group of 60 - 80 year (P < 0.001), presence of co-morbidities (P < 0.001)and history of smoking & alcohol consumption (P < 0.001). Among co-morbiditiesdiabetes-mellitus, hypertension, chronic-respiratory-diseases & chronic-kidneydiseases had significant impact on mortality. Absence of co-morbidity, lack ofaddiction and symptoms at the time of presentation were associated with anearlier conversion of reverse transcription polymerase chain reaction (RT-PCR)report.CONCLUSIONSClinical spectrum of COVID 19 varies widely. Presence of comorbidities, addiction,radiological features has a drastic impact on mortality and duration of infectivity.
Piyush Arora, Himanshu Mittal, Neeraj Gupta, Jose K. Jimmy
Journal of Evidence Based Medicine and Healthcare