159 10 20655 https://www.socictopen.socict.org/files/original/84d09daedb3f7cba203518fce4527406.pdf 38996f643463bad9b7bc1a2d597e6320 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Seropositive Camel Handlers in Kenya Creator An entity primarily responsible for making the resource Alice N. Kiyong’a, Elizabeth A.J. Cook, Nisreen M.A. Okba, Velma Kivali, Chantal Reusken, Bart L. Haagmans, Eric M. Fèvre Description An account of the resource Middle East respiratory syndrome (MERS) is a respiratory disease caused by a zoonotic coronavirus (MERS-CoV). Camel handlers, including slaughterhouse workers and herders, are at risk of acquiring MERS-CoV infections. However, there is limited evidence of infections among camel handlers in Africa. The purpose of this study was to determine the presence of antibodies to MERS-CoV in high-risk groups in Kenya. Sera collected from 93 camel handlers, 58 slaughterhouse workers and 35 camel herders, were screened for MERS-CoV antibodies using ELISA and PRNT. We found four seropositive slaughterhouse workers by PRNT. Risk factors amongst the slaughterhouse workers included being the slaughterman (the person who cuts the throat of the camel) and drinking camel blood. Further research is required to understand the epidemiology of MERS-CoV in Africa in relation to occupational risk, with a need for additional studies on the transmission of MERS-CoV from dromedary camels to humans, seroprevalence and associated risk factors. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource coronavirus, camels, Republic of Kenya, slaughterhouses Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/v12040396 Source A related resource from which the described resource is derived Viruses Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology Language A language of the resource EN https://www.socictopen.socict.org/files/original/e8683dbef7baa28f045791ee61c73388.pdf 213b2b198f38d98cc5f91cef0ef59021 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Ostwald Growth Rate in Controlled Covid-19 Epidemic Spreading as in Arrested Growth in Quantum Complex Matter Creator An entity primarily responsible for making the resource Antonio Bianconi, Augusto Marcelli, Gaetano Campi, Andrea Perali Description An account of the resource Here, we focus on the data analysis of the growth of epidemic spread of Covid-19 in countries where different policies of containment were activated. It is known that the growth of pandemic spread at its threshold is exponential, but it is not known how to quantify the success of different containment policies. We identify that a successful approach gives an arrested phase regime following the Ostwald growth, where, over the course of time, one phase transforms into another metastable phase with a similar free energy as observed in oxygen interstitial diffusion in quantum complex matter and in crystallization of proteins. We introduce the s factor which provides a quantitative measure of the efficiency and speed of the adopted containment policy, which is very helpful not only to monitor the Covid-19 pandemic spread but also for other countries to choose the best containment policy. The results show that a policy based on joint confinement, targeted tests, and tracking positive cases is the most rapid pandemic containment policy; in fact, we found values of 9, 5, and 31 for the success s factor for China, South Korea, and Italy, respectively, where the lowest s factor indicates the best containment policy. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource COVID-19, epidemic control policies, biophysical approach, Ostwald arrested growth, big data analysis, success s factor Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/condmat5020023 Source A related resource from which the described resource is derived Condensed Matter Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Physics Language A language of the resource EN https://www.socictopen.socict.org/files/original/224a66838fcbaaf9b8396cfe9e813b9a.pdf b28181608dbc7c492c2f24cabe2dc22f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Impact of the COVID-19 Pandemic on Mental Health and Quality of Life among Local Residents in Liaoning Province, China: A Cross-Sectional Study Creator An entity primarily responsible for making the resource Yingfei Zhang, Zheng Feei Ma Description An account of the resource Our study aimed to investigate the immediate impact of the COVID-19 pandemic on mental health and quality of life among local Chinese residents aged ≥18 years in Liaoning Province, mainland China. An online survey was distributed through a social media platform between January and February 2020. Participants completed a modified validated questionnaire that assessed the Impact of Event Scale (IES), indicators of negative mental health impacts, social and family support, and mental health-related lifestyle changes. A total of 263 participants (106 males and 157 females) completed the study. The mean age of the participants was 37.7 ± 14.0 years, and 74.9% had a high level of education. The mean IES score in the participants was 13.6 ± 7.7, reflecting a mild stressful impact. Only 7.6% of participants had an IES score ≥26. The majority of participants (53.3%) did not feel helpless due to the pandemic. On the other hand, 52.1% of participants felt horrified and apprehensive due to the pandemic. Additionally, the majority of participants (57.8–77.9%) received increased support from friends and family members, increased shared feeling and caring with family members and others. In conclusion, the COVID-19 pandemic was associated with mild stressful impact in our sample, even though the COVID-19 pandemic is still ongoing. These findings would need to be verified in larger population studies. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource coronavirus, Mental health, IES, Pandemic, China Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/ijerph17072381 Source A related resource from which the described resource is derived International Journal of Environmental Research and Public Health Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/c0a4c076c800428574399a447829618b.pdf 806e17267a032087536b11e79684b8b4 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The Diamond Princess Cruise: An Accidentally Experimental Model of Virus Pneumonia Creator An entity primarily responsible for making the resource Liyuan 里远 Liu 刘 Description An account of the resource On February 2020, the Diamond Princess Cruise, which left Japan, was obliged to stay at sea for 14 days-quarantine after it was found that a Hong Kong passenger had been diagnosed SARS-COV2 pneumonia after disembarking. As a result shocked the world, an outbreak of infection occurred on board; the number of infected people increased rapidly; and about 20% of the population infected. Finally, the quarantine is completely failed and has to be ended officially. The crowd was evacuated back to their own country. The incident can be seen as an experimental model of virus infection in an independently enclosed building, showing powerful air-borne transmission of the virus to pass through public ventilation ducts and crevices in doors and windows. There have trend that no is immune; there have no racial differences and all world people are generally susceptible. The populations of asymptomatic recessive infection are large and are a dangerous infection source. The failure of closed quarantine indicates that evacuation is the best quarantine and protection. To sum up, mistake quarantine = forced infection; ineffective quarantine = condoning spreading; excessive quarantine = wasting resources. The only right way is to evacuate the infected immediately and disperse the uninfected quickly. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Diamond Princess cruise, SARS-CoV-2, COVID-2019, viral pneumonia, infecting model, residential building infection Identifier An unambiguous reference to the resource within a given context DOI: 10.2991/jracr.k.200415.002 Source A related resource from which the described resource is derived Journal of Risk Analysis and Crisis Response (JRACR) Publisher An entity responsible for making the resource available Atlantis Press Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Engineering (General). Civil engineering (General), Risk in industry. Risk management Language A language of the resource EN https://www.socictopen.socict.org/files/original/c25ed21a29ec1eb8e3d48533e3bae806.pdf 18eae226d4911288d1387d9b48cd4bba Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The transmissibility of novel Coronavirus in the early stages of the 2019-20 outbreak in Wuhan: Exploring initial point-source exposure sizes and durations using scenario analysis [version 1; peer review: 2 approved] Creator An entity primarily responsible for making the resource Sam Abbott, Joel Hellewell, James Munday, CMMID nCoV working group, Sebastian Funk Description An account of the resource Background: The current novel coronavirus outbreak appears to have originated from a point-source exposure event at Huanan seafood wholesale market in Wuhan, China. There is still uncertainty around the scale and duration of this exposure event. This has implications for the estimated transmissibility of the coronavirus and as such, these potential scenarios should be explored.  Methods: We used a stochastic branching process model, parameterised with available data where possible and otherwise informed by the 2002-2003 Severe Acute Respiratory Syndrome (SARS) outbreak, to simulate the Wuhan outbreak. We evaluated scenarios for the following parameters: the size, and duration of the initial transmission event, the serial interval, and the reproduction number (R0). We restricted model simulations based on the number of observed cases on the 25th of January, accepting samples that were within a 5% interval on either side of this estimate. Results: Using a pre-intervention SARS-like serial interval suggested a larger initial transmission event and a higher R0 estimate. Using a SARs-like serial interval we found that the most likely scenario produced an R0 estimate between 2-2.7 (90% credible interval (CrI)). A pre-intervention SARS-like serial interval resulted in an R0 estimate between 2-3 (90% CrI). There were other plausible scenarios with smaller events sizes and longer duration that had comparable R0 estimates. There were very few simulations that were able to reproduce the observed data when R0 was less than 1. Conclusions: Our results indicate that an R0 of less than 1 was highly unlikely unless the size of the initial exposure event was much greater than currently reported. We found that R0 estimates were comparable across scenarios with decreasing event size and increasing duration. Scenarios with a pre-intervention SARS-like serial interval resulted in a higher R0 and were equally plausible to scenarios with SARs-like serial intervals. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context DOI: 10.12688/wellcomeopenres.15718.1 Source A related resource from which the described resource is derived Wellcome Open Research Publisher An entity responsible for making the resource available Wellcome Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Science, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/c9be44059abe2e21f29b8c25533d58e9.pdf 5aa7543b3274b14d2f62077004506a97 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Progress and Prospects on Vaccine Development against SARS-CoV-2 Creator An entity primarily responsible for making the resource Jinyong Zhang, Hao Zeng, Jiang Gu, Hai-Bo Li, Lixin Zheng, Quanming Zou Description An account of the resource In December 2019, the outbreak of pneumonia caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to a serious pandemic in China and other countries worldwide. So far, more than 460,000 confirmed cases were diagnosed in nearly 190 countries, causing globally over 20,000 deaths. Currently, the epidemic is still spreading and there is no effective means to prevent the infection. Vaccines are proved to be the most effective and economical means to prevent and control infectious diseases. Several countries, companies, and institutions announced their programs and progress on vaccine development against the virus. While most of the vaccines are under design and preparation, there are some that have entered efficacy evaluation in animals and initial clinical trials. This review mainly focused on the progress and our prospects on field of vaccine development against SARS-CoV-2. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource SARS-CoV-2, vaccine, adjuvant, Animal model Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/vaccines8020153 Source A related resource from which the described resource is derived Vaccines Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/01a6027ea0368895554500d8b5c4e443.pdf 711b83e00e3f031dc0ba1cf00a2b20ae Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Process-Induced Nanostructures on Anatase Single Crystals via Pulsed-Pressure MOCVD Creator An entity primarily responsible for making the resource Rukmini Gorthy, Susan Krumdieck, Catherine Bishop Description An account of the resource The recent global pandemic of COVID-19 highlights the urgent need for practical applications of anti-microbial coatings on touch-surfaces. Nanostructured TiO2 is a promising candidate for the passive reduction of transmission when applied to handles, push-plates and switches in hospitals. Here we report control of the nanostructure dimension of the mille-feuille crystal plates in anatase columnar crystals as a function of the coating thickness. This nanoplate thickness is key to achieving the large aspect ratio of surface area to migration path length. TiO2 solid coatings were prepared by pulsed-pressure metalorganic chemical vapor deposition (pp-MOCVD) under the same deposition temperature and mass flux, with thickness ranging from 1.3–16 μm, by varying the number of precursor pulses. SEM and STEM were used to measure the mille-feuille plate width which is believed to be a key functional nano-dimension for photocatalytic activity. Competitive growth produces a larger columnar crystal diameter with thickness. The question is if the nano-dimension also increases with columnar crystal size. We report that the nano-dimension increases with the film thickness, ranging from 17–42 nm. The results of this study can be used to design a coating which has co-optimized thickness for durability and nano-dimension for enhanced photocatalytic properties. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource anatase single crystals, process-induced nanostructures, Competitive growth, pp-MOCVD Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/ma13071668 Source A related resource from which the described resource is derived Materials Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Technology, Engineering (General). Civil engineering (General), Electrical engineering. Electronics. Nuclear engineering, Microscopy, Descriptive and experimental mechanics Language A language of the resource EN https://www.socictopen.socict.org/files/original/35569d4e4721f161f8bde276b4741511.pdf 0149cea6f7b0b1898765ab33d3988bb0 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Structure–Activity Relationships and Molecular Docking Analysis of Mcl-1 Targeting Renieramycin T Analogues in Patient-derived Lung Cancer Cells Creator An entity primarily responsible for making the resource Korrakod Petsri, Masashi Yokoya, Sucharat Tungsukruthai, Thanyada Rungrotmongkol, Bodee Nutho, Chanida Vinayanuwattikun, Naoki Saito, Matsubara Takehiro, Ryo Sato, Pithi Chanvorachote Description An account of the resource Myeloid cell leukemia 1 (Mcl-1) and B-cell lymphoma 2 (Bcl-2) proteins are promising targets for cancer therapy. Here, we investigated the structure–activity relationships (SARs) and performed molecular docking analysis of renieramycin T (RT) and its analogues and identified the critical functional groups of Mcl-1 targeting. RT have a potent anti-cancer activity against several lung cancer cells and drug-resistant primary cancer cells. RT mediated apoptosis through Mcl-1 suppression and it also reduced the level of Bcl-2 in primary cells. For SAR study, five analogues of RT were synthesized and tested for their anti-cancer and Mcl-1- and Bcl-2-targeting effects. Only two of them (TM-(–)-18 and TM-(–)-4a) exerted anti-cancer activities with the loss of Mcl-1 and partly reduced Bcl-2, while the other analogues had no such effects. Specific cyanide and benzene ring parts of RT’s structure were identified to be critical for its Mcl-1-targeting activity. Computational molecular docking indicated that RT, TM-(–)-18, and TM-(–)-4a bound to Mcl-1 with high affinity, whereas TM-(–)-45, a compound with a benzene ring but no cyanide for comparison, showed the lowest binding affinity. As Mcl-1 helps cancer cells evading apoptosis, these data encourage further development of RT compounds as well as the design of novel drugs for treating Mcl-1-driven cancers. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Renieramycin T, structure–activity relationship, patient-derived primary lung cancer cells, lung cancer, apoptosis, Mcl-1 Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/cancers12040875 Source A related resource from which the described resource is derived Cancers Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Neoplasms. Tumors. Oncology. Including cancer and carcinogens Language A language of the resource EN https://www.socictopen.socict.org/files/original/fa1de2dcda13692a0eea4416f508d936.pdf 5fed6e6f68183407df1762ccf37d369f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Development of a Novel, Genome Subtraction-Derived, SARS-CoV-2-Specific COVID-19-nsp2 Real-Time RT-PCR Assay and Its Evaluation Using Clinical Specimens Creator An entity primarily responsible for making the resource Cyril Chik-Yan Yip, Chi-Chun Ho, Jasper Fuk-Woo Chan, Kelvin Kai-Wang To, Helen Shuk-Ying Chan, Sally Cheuk-Ying Wong, Kit-Hang Leung, Agnes Yim-Fong Fung, Anthony Chin-Ki Ng, Zijiao Zou, Anthony Raymond Tam, Tom Wai-Hin Chung, Kwok-Hung Chan, Ivan Fan-Ngai Hung, Vincent Chi-Chung Cheng, Owen Tak-yin Tsang, Stephen Kwok-Wing Tsui, Kwok-yung Yuen Description An account of the resource The pandemic novel coronavirus infection, Coronavirus Disease 2019 (COVID-19), has affected at least 190 countries or territories, with 465,915 confirmed cases and 21,031 deaths. In a containment-based strategy, rapid, sensitive and specific testing is important in epidemiological control and clinical management. Using 96 SARS-CoV-2 and 104 non-SARS-CoV-2 coronavirus genomes and our in-house program, GolayMetaMiner, four specific regions longer than 50 nucleotides in the SARS-CoV-2 genome were identified. Primers were designed to target the longest and previously untargeted nsp2 region and optimized as a probe-free real-time reverse transcription-polymerase chain reaction (RT-PCR) assay. The new COVID-19-nsp2 assay had a limit of detection (LOD) of 1.8 TCID50/mL and did not amplify other human-pathogenic coronaviruses and respiratory viruses. Assay reproducibility in terms of cycle threshold (Cp) values was satisfactory, with the total imprecision (% CV) values well below 5%. Evaluation of the new assay using 59 clinical specimens from 14 confirmed cases showed 100% concordance with our previously developed COVID-19-RdRp/Hel reference assay. A rapid, sensitive, SARS-CoV-2-specific real-time RT-PCR assay, COVID-19-nsp2, was developed. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource SARS-CoV-2, COVID-19, Nsp2, Real-time RT-PCR, genome subtraction, GolayMetaMiner Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/ijms21072574 Source A related resource from which the described resource is derived International Journal of Molecular Sciences Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General), Chemistry Language A language of the resource EN https://www.socictopen.socict.org/files/original/d316570327c692d67c500103337876f4.pdf 1924ef42a60e40cb32a6017fb06dffa6 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Viruses of Respiratory Tract: an Observational Retrospective Study on Hospitalized Patients in Rome, Italy Creator An entity primarily responsible for making the resource Marco Ciotti, Massimo Maurici, Viviana Santoro, Luigi Coppola, Loredana Sarmati, Gerardo De Carolis, Patrizia De Filippis, Francesca Pica Description An account of the resource Respiratory tract infections account for high morbidity and mortality around the world. Fragile patients are at high risk of developing complications such as pneumonia and may die from it. Limited information is available on the extent of the circulation of respiratory viruses in the hospital setting. Most knowledge relates to influenza viruses (FLU) but several other viruses produce flu-like illness. The study was conducted at the University Hospital Policlinico Tor Vergata, Rome, Italy. Clinical and laboratory data from hospitalized patients with respiratory tract infections during the period October 2016–March 2019 were analysed. The retrospective analysis included 17 viral agents detected by FilmArray test and clinical data from medical records and hospital discharge sheets. Models were adjusted for relevant confounders such as clinical severity and risk of death, socio-demographic characteristics and surgical procedures. From a total of 539 specimens analysed, 180 (33.39%) were positive for one or more respiratory viruses. Among them, 83 (46.1 %) were positive for influenza viruses (FLU), 36 (20%) rhino/enteroviruses (RHV/EV), 17 (9.44%) human coronaviruses (HCOV-229E, -HKU1, -NL63, and -OC43), 17 (9.44%) respiratory syncytial virus, 15 (8.33%) human metapneumovirus (HMPV), 8 (4.44%) parainfluenza viruses (PIV) and 4 (2.22%) adenoviruses (ADV). The distribution of viral agents varied across age groups and month of detection. The positive specimens were from 168 patients [102 M, 66 F; median age (range): 64 years (19−93)]. Overall, 40% of them had a high-grade clinical severity and a 27% risk of death; 27 patients died and 22 of them (81.5%) had received a clinical diagnosis of pneumonia. Respiratory viral infections may have a severe course and a poor prognosis in hospitalized patients, due to underlying comorbidities. Monitoring the circulation of respiratory viruses in hospital settings is important to improve diagnosis, prevention and treatment. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource influenza, influenza-like illness, Respiratory viruses, PCR, Hospitalized Patients Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/microorganisms8040501 Source A related resource from which the described resource is derived Microorganisms Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General) Language A language of the resource EN