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                <text>Coronavirus disease 2019 caused by a novel coronavirus was first identified in Wuhan, China and rapidly spread across the world. With the COVID-19 outbreak, a penury of PPE was seen all over the word and especially in FFP2 masks, which is due to high demand and the closure of almost all factories especially in China. Faced with this shortage, health workers had to find ways to protect themselves while waiting for the arrival of standard means. The idea started in some European hospitals and then medical offices whom begin to use Easybreath Decathlon mask which is characterized by its high sealing as a mean of personal protective equipment to substitute at the same time to FFP2 masks and face shield. It could be fundamental and may save many health workers to distribute Easybreath Decathlon mask to all African hospitals whom are fighting COVID-19 infection.</text>
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                <text>Cardiovascular Impacts of COVID-19 Pandemic: From Presentation to Management: Current and Future Perspectives</text>
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                <text>Zainab Atiyah Dakhil, Hasan Ali Farhan</text>
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            <description>An account of the resource</description>
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                <text>Corona virus disease 2019 (COVID-19) pandemic represents a global unprecedented healthcare crisis that results in respiratory syndrome and can cause remarkable cardiovascular impacts in form of myocardial injury, myocarditis, heart failure and arrhythmia. This review aimed to provide clinical landscape of this novel virus in the context of cardiovascular system involvement, in addition to explore future perspectives regarding response of healthcare system to this outbreak. The study showed that elderly patients and those with comorbidities are most susceptible for this infection, and will have the worst prognosis. Poor prognostic determinants for this disease were higher C-reactive protein, IL-6, ferritin, serum troponin and NT-ProBNP. Considering prominent role of COVID19 pandemic on cardiovascular health and care on multiple levels there is no time better than now for cardiology community to play a key role in fighting this pandemic globally in form of solidarity with other specialities and accelerating knowledge about this health threat in addition to adopt new perspectives on learning and training to face this unprecedented crisis.</text>
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                <text>DOI: 10.5799/jcei/7941</text>
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                <text>Journal of Clinical and Experimental Investigations</text>
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                <text>Association of Health Investigations</text>
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                <text>Medicine</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>COVID-19 Tragic Pandemic: Concerns over Unintentional “Directed Accelerated Evolution” of Novel Coronavirus (SARS-CoV-2) and Introducing a Modified Treatment Method for ARDS</text>
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                <text>A Ghadimi Moghadam, M. Haghani, JJ Bevelacqua, A. Jafarzadeh, A Kaveh-Ahangar, S.M.J. Mortazavi, S A R Mortazavi</text>
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                <text>Global health authorities are trying to work out the current status of the novel coronavirus (COVID-19) outbreak and explore methods to reduce the rate of its transmission to healthy individuals. In this viewpoint we provide insights concerning how health care professionals can unintentionally shift the novel coronavirus type to more drug-resistant forms. It is worth noting that viruses usually have different sensitivities to physical and chemical damaging agents such antiviral drugs, UV and heat ranging from extremely sensitive (ES) to extremely resistant (ER) based on a bell-shaped curve. Given this consideration, the widespread infection of people with such ER viruses would be a real disaster. Here, we introduce a modified treatment method for COVID-19-associated pneumonia. In this proposed method, COVID-19 patients will receive a single dose of 100, 180 or 250 mSv X-ray radiation that is less than the maximum annual radiation dose of the residents of high background radiation areas of Ramsar that is up to 260 mSv. In contrast with antiviral drugs, a single dose of either 100, 180 or 250 mSv of low LET X-rays cannot exert a significant selective pressure on the novel coronavirus (SARS-CoV-2) and hence does not lead to directed accelerated evolution of these viruses. Moreover, Low Dose Radiation (LDR) has the capacity of modulating excessive inflammatory responses, regulating lymphocyte counts, and controling bacterial co-infections in patients with COVID-19.</text>
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                <text>coronavirus, X-rays, respiratory distress syndrome, Radiation Dosage, selective pressure, directed evolution</text>
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                <text>DOI: 10.31661/jbpe.v0i0.2003-1085</text>
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                <text>Journal of Biomedical Physics and Engineering</text>
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            <description>An entity responsible for making the resource available</description>
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                <text>Shiraz University of Medical Sciences</text>
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                <text>Medical physics. Medical radiology. Nuclear medicine</text>
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            <description>A language of the resource</description>
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                <text>Asymptomatic COVID-19 Infection Management: The Key to Stop COVID-19</text>
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                <text>Rachid Ait Addi, Abdelhafid Benksim, Mohamed Amine, Mohamed Cherkaoui</text>
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                <text>The COVID-19 disease, emerged in December 2019, has spread rapidly, with new cases confirmed in multiple countries. Many efforts to contain the virus are ongoing, such as containment, individual measures of protection, the authorization of use of some drugs as chloquorine in some countries. Also, it has been known that symptomatic and asymptomatic people whom are infected by COVID-19 have the same contagiousness which expose a far greater portion of the population to virus and increase the late diagnosis and thereafter enhance COVID-19 mortality. Thereafter, it is fundamental to review our COVID-19 screening approach and enlarge COVID-19 testing to the general population by using rapid testing appliances such as rapid SARS-CoV-2 IgG-IgM combined antibody since another appliance more efficient will be performed.</text>
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                <text>DOI: 10.5799/jcei/7866</text>
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                <text>Journal of Clinical and Experimental Investigations</text>
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                <text>Association of Health Investigations</text>
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                <text>Impact of the Regulators SigB, Rot, SarA and sarS on the Toxic Shock Tst Promoter and TSST-1 Expression in Staphylococcus aureus.</text>
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              <elementText elementTextId="2566">
                <text>Diego O. Andrey, Ambre Jousselin, Maite Villanueva, Adriana Renzoni, Antoinette Monod, Christine Barras, Natalia Rodríguez, William L Kelley</text>
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                <text>Staphylococcus aureus is an important pathogen manifesting virulence through diverse disease forms, ranging from acute skin infections to life-threatening bacteremia or systemic toxic shock syndromes. In the latter case, the prototypical superantigen is TSST-1 (Toxic Shock Syndrome Toxin 1), encoded by tst(H), and carried on a mobile genetic element that is not present in all S. aureus strains. Transcriptional regulation of tst is only partially understood. In this study, we dissected the role of sarA, sarS (sarH1), RNAIII, rot, and the alternative stress sigma factor sigB (σB). By examining tst promoter regulation predominantly in the context of its native sequence within the SaPI1 pathogenicity island of strain RN4282, we discovered that σB emerged as a particularly important tst regulator. We did not detect a consensus σB site within the tst promoter, and thus the effect of σB is likely indirect. We found that σB strongly repressed the expression of the toxin via at least two distinct regulatory pathways dependent upon sarA and agr. Furthermore rot, a member of SarA family, was shown to repress tst expression when overexpressed, although its deletion had no consistent measurable effect. We could not find any detectable effect of sarS, either by deletion or overexpression, suggesting that this regulator plays a minimal role in TSST-1 expression except when combined with disruption of sarA. Collectively, our results extend our understanding of complex multifactorial regulation of tst, revealing several layers of negative regulation. In addition to environmental stimuli thought to impact TSST-1 production, these findings support a model whereby sporadic mutation in a few key negative regulators can profoundly affect and enhance TSST-1 expression.</text>
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                <text>2015</text>
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                <text>DOI: 10.1371/journal.pone.0135579</text>
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                <text>PLoS ONE</text>
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        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Correction: Middle East Respiratory Syndrome Coronavirus Intra-Host Populations Are Characterized by Numerous High Frequency Variants.</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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                <text>Monica K. Borucki, Victoria Lao, Mona Hwang, Shea Gardner, Danielle Adney, Vincent Munster, Richard Bowen, Jonathan E Allen</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>[This corrects the article DOI: 10.1371/journal.pone.0146251.].</text>
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            <name>Date</name>
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                <text>2016</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>DOI: 10.1371/journal.pone.0154424</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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                <text>PLoS ONE</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>Public Library of Science (PLoS)</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Science, Medicine</text>
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            <name>Language</name>
            <description>A language of the resource</description>
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                <text>EN</text>
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