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ERROR CORRECTION METHOD FOR SEQUENCING DATA WITH INSERTIONS AND DELETIONS
Subject of Research.A method for error correction for sequencing reads of a haploid organism with insertions and deletions was developed. It was tested on two libraries: a synthesized dataset for Escherichia coli bacterium and a real dataset of reads…
Position: 1075 (60 views)
A post-synaptic scaffold at the origin of the animal kingdom.
The evolution of complex sub-cellular structures such as the synapse requires the assembly of multiple proteins, each conferring added functionality to the integrated structure. Tracking the early evolution of synapses has not been possible without…
Position: 889 (63 views)
Alphacoronaviruses in New World bats: prevalence, persistence, phylogeny, and potential for interaction with humans.
Bats are reservoirs for many different coronaviruses (CoVs) as well as many other important zoonotic viruses. We sampled feces and/or anal swabs of 1,044 insectivorous bats of 2 families and 17 species from 21 different locations within Colorado from…
Position: 3424 (41 views)
COMPARISON OF STRESS PROTEINS PARTICIPATION IN ADAPTATION MECHANISMS OF BAIKALIAN AND PALEARCTIC AMPHIPOD (AMPHIPODA; CRUSTACEA) SPECIES
The aim of the present study was a study of the influence different stressful factor on syntheses and activity of the stress proteins (HSP70, sHSP and peroxidase) of freshwater organism. Six freshwater amphipod species were investigated:…
Position: 3092 (43 views)
Microorganisms Causing Community-Acquired Acute Bronchitis: The Role of Bacterial Infection.
Although acute bronchitis is quite common, there is relatively limited information regarding the microorganisms that are involved in this illness.We performed a prospective study of acute bronchitis at 31 hospitals and clinics in Korea from July 2011…
Position: 2149 (49 views)
Characterization of the Role of Hexamer AGUAAA and Poly(A) Tail in Coronavirus Polyadenylation.
Similar to eukaryotic mRNA, the positive-strand coronavirus genome of ~30 kilobases is 5'-capped and 3'-polyadenylated. It has been demonstrated that the length of the coronaviral poly(A) tail is not static but regulated during infection; however,…
Position: 3253 (42 views)
Mild encephalopathy with a reversible splenial lesion in a girl with acute pyelonephritis
We report the case of a 12-year-old girl who had mild encephalopathy with a reversible splenial lesion (MERS) associated with acutepyelonephritis caused by Escherichia coli. The patient was admitted with a high fever, and she was diagnosed with acute…
Position: 1075 (60 views)
A new species of Parategastes Sars, 1904 from the Thale Noi Lake, southern Thailand (Copepoda, Harpacticoida, Tegastidae)
Parategastes pholpunthini sp. n. is described and illustrated based on material collected in the Thale Noi Lake, Phatthalung province, southern Thailand. This species can be distinguished from its congeners by the number segments of female antennule,…
Position: 1014 (61 views)
BEST: improved prediction of B-cell epitopes from antigen sequences.
Accurate identification of immunogenic regions in a given antigen chain is a difficult and actively pursued problem. Although accurate predictors for T-cell epitopes are already in place, the prediction of the B-cell epitopes requires further…
Position: 2931 (44 views)
Comparative pathogenesis of three human and zoonotic SARS-CoV strains in cynomolgus macaques.
The severe acute respiratory syndrome (SARS) epidemic was characterized by increased pathogenicity in the elderly due to an early exacerbated innate host response. SARS-CoV is a zoonotic pathogen that entered the human population through an…
Position: 1576 (54 views)