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Social Isolation and Stress as Predictors of Productivity Perception and Remote Work Satisfaction during the COVID-19 Pandemic: The Role of Concern about the Virus in a Moderated Double Mediation
From mid-March to the end of May 2020, millions of Italians were forced to work from home because of the lockdown provisions imposed by the Italian government to contain the COVID-19 epidemic. As a result, many employees had to suddenly switch to…
Position: 10872 (32 views)
To form children health behaviour during the Covid-19 Pandemic: Teacher's strategy and obstacle
The Covid-19 pandemic is forcing everyone to change their behaviour to become more concerned about their health. This study aimed to illustrate the teachers’ strategy and the obstacle in shaping health behaviours of children in school. By using a…
Position: 18636 (22 views)
Ethical and cognitive challanges in the COVID-19 emergency
The global emergency caused by the spread of COVID-19 raises critical challenges for individuals and communities on many different levels. In particular, politicians, scientists, physicians, and other professionals may face new ethical dilemmas and…
Position: 13218 (29 views)
Severe COVID-19: NLRP3 Inflammasome Dysregulated
SARS-CoV-2 might directly activate NLRP3 inflammasome resulting in an endogenous adjuvant activity necessary to mount a proper adaptive immune response against the virus. Heterogeneous response of COVID-19 patients could be attributed to differences…
Position: 16599 (25 views)
Attach importance of the bootstrap t test against Student's t test in clinical epidemiology: a demonstrative comparison using COVID-19 as an example.
Student's t test is valid for statistical inference under the normality assumption or asymptotically. By contrast, although the bootstrap t test was proposed in 1993, it is seldom adopted in medical research. We aim to demonstrate that the bootstrap…
Position: 18046 (23 views)
Functional studies of the coronavirus nonstructural proteins
Coronaviruses, including SARS-CoV, SARS-CoV-2, and MERS-CoV, have caused contagious and fatal respiratory diseases in humans worldwide. Notably, the coronavirus disease 19 (COVID-19) caused by SARS-CoV-2 spread rapidly in early 2020 and became a…
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Medical Overuse in the Iranian Healthcare System: A Systematic Scoping Review and Practical Recommendations for Decreasing Medical Overuse During Unexpected COVID-19 Pandemic Opportunity
Mohammad Zakaria Pezeshki,1 Ali Janati,2 Morteza Arab-Zozani3,4 1Social Determinants of Health Research Center, Department of Community and Family Medicine, Tabriz Medical School, Tabriz University of Medical Sciences, Tabriz, Iran; 2Iranian Center…
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Conducting Phase I Trials During the SARS-Coronavirus-2 Outbreak: About Science and Care
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Is it Kawasaki shock syndrome, Kawasaki-like disease or pediatric inflammatory multisystem disease? The importance of semantic in the era of COVID-19 pandemic
A few weeks after the peak of the global 2019 novel coronavirus disease pandemic, cases of shock, multisystem inflammation and severe myocarditis have occurred in children and adolescents, generating some concerns and above all many questions. An…
Position: 11606 (31 views)
Using All-Atom Potentials to Refine RNA Structure Predictions of SARS-CoV-2 Stem Loops
A considerable amount of rapid-paced research is underway to combat the SARS-CoV-2 pandemic. In this work, we assess the 3D structure of the 5′ untranslated region of its RNA, in the hopes that stable secondary structures can be targeted,…
Position: 19650 (20 views)