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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Alternative Global Health Security Indexes for Risk Analysis of COVID-19</text>
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                <text>Michael McAleer, Chia-Lin Chang</text>
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                <text>Given the volume of research and discussion on the health, medical, economic, financial, political, and travel advisory aspects of the SARS-CoV-2 virus that causes the COVID-19 disease, it is essential to enquire if an outbreak of the epidemic might have been anticipated, given the well-documented history of SARS and MERS, among other infectious diseases. If various issues directly related to health security risks could have been predicted accurately, public health and medical contingency plans might have been prepared and activated in advance of an epidemic such as COVID-19. This paper evaluates an important source of health security, the Global Health Security Index (2019), which provided data before the discovery of COVID-19 in December 2019. Therefore, it is possible to evaluate how countries might have been prepared for a global epidemic, or pandemic, and acted accordingly in an effective and timely manner. The GHS index numerical scores are calculated as the arithmetic (AM), geometric (GM), and harmonic (HM) means of six categories, where AM uses equal weights for each category. The GHS Index scores are regressed on the numerical score rankings of the six categories to check if the use of equal weights of 0.167 in the calculation of the GHS Index using AM is justified, with GM and HM providing a check of the robustness of the arithmetic mean. The highest weights are determined to be around 0.244–0.246, while the lowest weights are around 0.186–0.187 for AM. The ordinal GHS Index is regressed on the ordinal rankings of the six categories to check for the optimal weights in the calculation of the ordinal Global Health Security (GHS) Index, where the highest weight is 0.368, while the lowest is 0.142, so the estimated results are wider apart than for the numerical score rankings. Overall, Rapid Response and Detection and Reporting have the largest impacts on the GHS Index score, whereas Risk Environment and Prevention have the smallest effects. The quantitative and qualitative results are different when GM and HM are used.</text>
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                <text>2020</text>
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                <text>Risk Management, Pandemic, COVID-19, global health security risk, Pythagorean means, numerical rankings</text>
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                <text>DOI: 10.3390/ijerph17093161</text>
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                <text>International Journal of Environmental Research and Public Health</text>
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                <text>Medicine</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Urgent Measures for the Containment of the Coronavirus (Covid-19) Epidemic in the Neurorehabilitation/Rehabilitation Departments in the Phase of Maximum Expansion of the Epidemic</text>
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                <text>Mauro Zampolini, Michelangelo Bartolo, Giorgio Sandrini, Domenico Intiso, Stefano Paolucci, Carmelo Lentino, The Board of the Italian Society of Neurological Rehabilitation (SIRN)</text>
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                <text>COVID-19 has rapidly become a pandemic emergency, distressing health systems in each affected country. COVID-19 determines the need for healthcare in a large number of people in an extremely short time and, like a tsunami wave, overruns emergency, infectious diseases, and pneumology departments as well as intensive care units, choking healthcare services. Rehabilitation services are also affected by this epidemic which forces radical changes both in the organization and in the operating methods. In the absence of reference literature on this issue, this report aims to provide a background documentation to support physicians and healthcare personnel involved in neurorehabilitation and rehabilitation care.</text>
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                <text>2020</text>
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                <text>rehabilitation, infection, healthcare, Neurorehabilitation, epidemic, COVID-19</text>
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                <text>DOI: 10.3389/fneur.2020.00423</text>
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                <text>Frontiers in Neurology</text>
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            <description>An entity responsible for making the resource available</description>
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                <text>Frontiers Media S.A.</text>
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                <text>Neurology. Diseases of the nervous system</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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            <description>A name given to the resource</description>
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                <text>Current and Future Point-of-Care Tests for Emerging and New Respiratory Viruses and Future Perspectives</text>
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            <description>An entity primarily responsible for making the resource</description>
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                <text>Sotirios Tsiodras, Barbara A. Rath, Paraskevi C. Fragkou, Emmanouil Antalis, Chrysanthi Skevaki, Philipp P. Nelson</text>
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                <text>The availability of pathogen-specific treatment options for respiratory tract infections (RTIs) increased the need for rapid diagnostic tests. Besides, retrospective studies, improved lab-based detection methods and the intensified search for new viruses since the beginning of the twenty-first century led to the discovery of several novel respiratory viruses. Among them are human bocavirus (HBoV), human coronaviruses (HCoV-HKU1, -NL63), human metapneumovirus (HMPV), rhinovirus type C (RV-C), and human polyomaviruses (KIPyV, WUPyV). Additionally, new viruses like SARS coronavirus (SARS-CoV), MERS coronavirus (MERS-CoV), novel strains of influenza virus A and B, and (most recently) SARS coronavirus 2 (SARS-CoV-2) have emerged. Although clinical presentation may be similar among different viruses, associated symptoms may range from a mild cold to a severe respiratory illness, and thus require a fast and reliable diagnosis. The increasing number of commercially available rapid point-of-care tests (POCTs) for respiratory viruses illustrates both the need for this kind of tests but also the problem, i.e., that the majority of such assays has significant limitations. In this review, we summarize recently published characteristics of POCTs and discuss their implications for the treatment of RTIs. The second key aspect of this work is a description of new and innovative diagnostic techniques, ranging from biosensors to novel portable and current lab-based nucleic acid amplification methods with the potential future use in point-of-care settings. While prototypes for some methods already exist, other ideas are still experimental, but all of them give an outlook of what can be expected as the next generation of POCTs.</text>
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                <text>2020</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>biosensors, bedside testing, POCT, innovative approaches, virus diagnostics, commercial point-of-care tests</text>
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            <description>An unambiguous reference to the resource within a given context</description>
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                <text>DOI: 10.3389/fcimb.2020.00181</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="30169">
                <text>Frontiers in Cellular and Infection Microbiology</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>Frontiers Media S.A.</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Microbiology</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Novel Coronavirus: How Atmospheric Particulate Affects Our Environment and Health</text>
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            <description>An entity primarily responsible for making the resource</description>
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                <text>Luigi Sanità di Toppi, Erika Bellini, Lorenzo Sanità di Toppi</text>
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                <text>It is well-known that atmospheric pollution, first and foremost the particulate matter (PM), causes serious diseases in humans. China’s metropolises and Italy’s Po Valley have in fact achieved a concerning degree of notoriety thanks to runaway air pollution problems. The spread of viral respiratory diseases is facilitated in polluted environments, an example of which is the respiratory syncytial virus bronchiolitis. In this opinion paper, we consider the possible relationship between air pollution, primarily airborne PM10–2.5, and the spread of the novel coronavirus in Northern Italy. If it is true that the novel coronavirus remains active from some hours to several days on various surfaces, it is logical to postulate that the same can occur when it is adsorbed or absorbed by the atmospheric particulate matter, which may also help carry the virus into the human respiratory system. As the Earth presents us with a very high bill to pay, governments and other authorities need to take prompt action to counter excessive pollution levels, both in Italy and in other countries.</text>
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                <text>2020</text>
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                <text>coronavirus, respiratory diseases, Particulate matter, Atmospheric Pollution, COVID-19</text>
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                <text>DOI: 10.3390/challe11010006</text>
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                <text>Challenges</text>
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            <description>An entity responsible for making the resource available</description>
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                <text>MDPI AG</text>
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                <text>Technology, Science (General)</text>
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                <text>East Asia\'s Strategies for Effective Response to COVID-19: Lessons Learned for Iran</text>
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                <text>Parinaz Doshmangir, Leila Doshmangir, Saber Azami-Aghdash, Rahim Khodayari Zarnaq, Khorshid Mobasseri, Alirez Mahbub Ahari, Kamal Qolipour, Leyla Kalankesh</text>
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                <text>The spread of the new Corona virus, known as COVID-19, has raised concerns and problems for many countries, and its out-of-China exposure is worryingly increasing. This trend is increasing in our country as well and has reached a critical point in some of the infected cities. This article attempts to provide appropriate strategies for controlling the virus for Iran based on the East Asia countries response that have had the first and most exposure to the virus.</text>
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                <text>Rāhburdhā-yi Mudīriyyat dar Niẓām-i Salāmat</text>
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            <name>Publisher</name>
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              <elementText elementTextId="30188">
                <text>Shahid Sadoughi University of Medical Sciences</text>
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                <text>Medicine (General)</text>
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              <name>Title</name>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Novel Coronavirus Disease 2019 Infection in Children: The Dark Side of a Worldwide Outbreak</text>
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                <text>Piero Valentini, Danilo Buonsenso, Giuseppe Zampino</text>
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            <description>An account of the resource</description>
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                <text>In this pediatric perspectives article, we discuss current limits in the understanding of novel coronavirus infection. In our opinion, the burden of novel coronavirus infections is underestimated because not actively looked for. We discuss the basis of our observations and what this can generate, suggesting a different approach for the search of the virus in children.</text>
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                <text>2020</text>
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                <text>Children, Public Health, coronavirus, SARS-CoV-2, COVID-19</text>
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            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="30195">
                <text>DOI: 10.3389/fped.2020.00215</text>
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            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="30196">
                <text>Frontiers in Pediatrics</text>
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            <name>Publisher</name>
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              <elementText elementTextId="30197">
                <text>Frontiers Media S.A.</text>
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            <name>Coverage</name>
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                <text>Pediatrics</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Physical Activity During the Coronavirus (COVID-19) Pandemic: Prevention of a Decline in Metabolic and Immunological Functions</text>
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            <description>An entity primarily responsible for making the resource</description>
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                <text>Johan Jakobsson, Ulf Ekelund, Maria Furberg, Christer Malm, Michael Svensson</text>
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                <text>Health, physical activity, Mortality, sedentary behavior, coronavirus, COVID-19</text>
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            <description>An unambiguous reference to the resource within a given context</description>
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                <text>DOI: 10.3389/fspor.2020.00057</text>
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            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="30204">
                <text>Frontiers in Sports and Active Living</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="30205">
                <text>Frontiers Media S.A.</text>
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              <elementText elementTextId="30206">
                <text>Sports</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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        <name>Dublin Core</name>
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                <text>The novel coronavirus (COVID-19) pneumonia with negative detection of viral ribonucleic acid from nasopharyngeal swabs: a case report</text>
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                <text>Li Chen, Jianming Li, Jing Yuan, Ling Peng, Liang Yang, Ying-xia Liu, Xiao Jiang, Chuming Chen, Yinfeng Li, Peiyan Zhang, Zhao Cai, Meng-Li Cao, Weibo Wu, Fuxiang Wang, Shiyan Feng</text>
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                <text>Abstract Background The novel coronavirus disease 2019 (COVID-19) outbreak started in Wuhan, Hubei, China since Dec 2019 and cases of infection have been continuously reported in various countries. It is now clear that the SARS-COV-2 coronavirus is transmissible from human to human. Nucleic acid detection is considered as the gold standard for the diagnosis of COVID-19. In this case report, we describe our experience in detection of SARS-COV-2 from a confirmed patient using nucleic acid test of bronchoalveolar-lavage fluid (BALF) samples but not nasopharyngeal swabs. Case presentation We present a case of severely ill SARS-COV-2 infected 46-year-old man with fever, coughing and chest tightness. We performed viral detection using his BALF samples and imaging method (CT) for confirmation. The patient received combination of interferonalfa-1b and ribavirin, lopinavir and ritonavir for antiviral treatment at different stages. Other medication was also given to him in combination for anti-inflammation, intestinal microbial regulation, phlegm elimination, liver protection and pulmonary fibrosis prevention purposes. We provided oxygen supply to him using BIPAP ventilator and high-flow humidification oxygen therapy instrument to facilitate respiration. The patient was cured and discharged. Conclusion This case report described an effective supportive medication scheme to treat SARS-COV-2 infected patient and emphasized the necessity of detection of the viral genome using BALF samples and its significance in the diagnosis and prognosis of the disease.</text>
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                <text>2020</text>
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                <text>Pneumonia, coronavirus, Bronchoalveolar Lavage Fluid, COVID-19, Tracheoscopy</text>
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                <text>DOI: 10.1186/s12879-020-05045-z</text>
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                <text>BMC Infectious Diseases</text>
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                <text>BMC</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Infectious and parasitic diseases</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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                <text>COVID-19: where is the national ethical guidance?</text>
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                <text>Richard Huxtable</text>
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                <text>2020</text>
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                <text>coronavirus, COVID-19, Professional guidance, ethical guidance</text>
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                <text>DOI: 10.1186/s12910-020-00478-2</text>
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                <text>BMC Medical Ethics</text>
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                <text>Medical philosophy. Medical ethics</text>
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            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="30224">
                <text>Coronavirus disease 2019 (COVID-19): What we need to know</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="30225">
                <text>Masomeh Bayani, Soheil Ebrahimpour, Mostafa Javanian, Jila Masrour-Roudsari</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="30226">
                <text>2020</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="30227">
                <text>infection, virus, coronavirus, COVID-19</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="30228">
                <text>DOI: </text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="30229">
                <text>Caspian Journal of Internal Medicine</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="30230">
                <text>Babol University of Medical Sciences</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="30231">
                <text>Internal medicine</text>
              </elementText>
            </elementTextContainer>
          </element>
        </elementContainer>
      </elementSet>
    </elementSetContainer>
  </item>
</itemContainer>
