331 10 20655 https://www.socictopen.socict.org/files/original/4c391c96f4f20e80f88107972249de8c.pdf 7ee55ef73a30abf7b505745ce537106a Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource MERS-CoV Spike Protein Vaccine and Inactivated Influenza Vaccine Formulated with Single Strand RNA Adjuvant Induce T-Cell Activation through Intranasal Immunization in Mice Creator An entity primarily responsible for making the resource Hye-Jung Kim, Kyungwon Kang, Hyo Jung Park, Sang-Myeong Lee, Jaeyong Kim, Hyeong-jun Park, Yu-Sun Lee, Jae-Hwan Nam, Hye-Won Kwak, Yoo-Jin Bang, Kyung-Ah Hwang Description An account of the resource The effectiveness of vaccines is enhanced by adding adjuvants. Furthermore, the selection of an inoculation route depends on the type of adjuvant used and is important for achieving optimum vaccine efficacy. We investigated the immunological differences between two types of vaccines—spike protein from the Middle East respiratory syndrome virus and inactivated influenza virus vaccine, in combination with a single-stranded RNA adjuvant—administered through various routes (intramuscular, intradermal, and intranasal) to BALB/c mice. Intramuscular immunization with the RNA adjuvant-formulated spike protein elicited the highest humoral immune response, characterized by IgG1 and neutralizing antibody production. Although intranasal immunization did not elicit a humoral response, it showed extensive T-cell activation through large-scale induction of interferon-γ- and interleukin-2-secreting cells, as well as CD4+ T-cell activation in mouse splenocytes. Moreover, only intranasal immunization induced IgA production. When immunized with the inactivated influenza vaccine, administration of the RNA adjuvant via all routes led to protection after viral challenge, regardless of the presence of a vaccine-specific antibody. Therefore, the inoculation route should depend on the type of immune response needed; i.e., the intramuscular route is suitable for eliciting a humoral immune response, whereas the intranasal route is useful for T-cell activation and IgA induction. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource inactivated vaccine, Intranasal immunization, intramuscular immunization, RNA adjuvant, protein-based vaccine, Middle East respiratory syndrome coronavirus (MERS-CoA) Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/pharmaceutics12050441 Source A related resource from which the described resource is derived Pharmaceutics Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Pharmacy and materia medica https://www.socictopen.socict.org/files/original/7e9063f69e240e21fe49ada27b25aee1.pdf 599bdbae687f6773a9908ddcaebd7cbf Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource SARS-CoV-2 Inflammatory Syndrome. Clinical Features and Rationale for Immunological Treatment Creator An entity primarily responsible for making the resource Vito Racanelli, Marcella Prete, Elvira Favoino, Giacomo Catacchio, Federico Perosa Description An account of the resource The current pandemic coronavirus, SARS-CoV-2, is a global health emergency because of its highly contagious nature, the great number of patients requiring intensive care therapy, and the high fatality rate. In the absence of specific antiviral drugs, passive prophylaxis, or a vaccine, the treatment aim in these patients is to prevent the potent virus-induced inflammatory stimuli from leading to the acute respiratory distress syndrome (ARDS), which has a severe prognosis. Here, the mechanism of action and the rationale for employing immunological strategies, which range from traditional chemically synthesized drugs, anti-cytokine antibodies, human immunoglobulin for intravenous use, to vaccines, are reviewed. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource inflammation, anti-cytokine antibodies, acute respiratory syndrome, SARS-CoV-2, COVID-19, human immunoglobulin for intravenous use Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/ijms21093377 Source A related resource from which the described resource is derived International Journal of Molecular Sciences Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General), Chemistry https://www.socictopen.socict.org/files/original/9d695cb9dbd55da55c1fc97fbdc09e09.pdf b87983f57757ac170adf3e181eed68ba Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource La situación de la enfermería en el mundo y la Región de las Américas en tiempos de la pandemia de COVID-19 Creator An entity primarily responsible for making the resource Marina Peduzzi, Silvia Helena De Bortoli Cassiani, Edgar Fernando Munar Jimenez, Augusto Umpiérrez Ferreira, Claudia Leija Hernández Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context DOI: 10.26633/RPSP.2020.64 Source A related resource from which the described resource is derived Revista Panamericana de Salud Pública Publisher An entity responsible for making the resource available Pan American Health Organization Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Arctic medicine. Tropical medicine, Public aspects of medicine, Medicine https://www.socictopen.socict.org/files/original/0ef4c426af259615d2b400ba4e707837.pdf f77548136bf0da34bde0a2111a4f6c08 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Prognostic Value of Cardiovascular Biomarkers in COVID-19: A Review Creator An entity primarily responsible for making the resource Brian Wang, Ashiq Abdul Khader, Maryam Aboughdir, Thomas Kirwin Description An account of the resource In early December 2019, the coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) first emerged in Wuhan, China. As of May 10th, 2020, a total of over 4 million COVID-19 cases and 280,000 deaths have been reported globally, reflecting the raised infectivity and severity of this virus. Amongst hospitalised COVID-19 patients, there is a high prevalence of established cardiovascular disease (CVD). There is evidence showing that COVID-19 may exacerbate cardiovascular risk factors and preexisting CVD or may lead to cardiovascular complications. With intensive care units operating at maximum capacity and such staggering mortality rates reported, it is imperative during this time-sensitive COVID-19 outbreak to identify patients with an increased risk of adverse outcomes and/or myocardial injury. Preliminary findings from COVID-19 studies have shown the association of biomarkers of acute cardiac injury and coagulation with worse prognosis. While these biomarkers are recognised for CVD, there is emerging prospect that they may aid prognosis in COVID-19, especially in patients with cardiovascular comorbidities or risk factors that predispose to worse outcomes. Consequently, the aim of this review is to identify cardiovascular prognostic factors associated with morbidity and mortality in COVID-19 and to highlight considerations for incorporating laboratory testing of biomarkers of cardiovascular performance in COVID-19 to optimise outcomes. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Cardiovascular disease, coronavirus, SARS-CoV-2, COVID-19 Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/v12050527 Source A related resource from which the described resource is derived Viruses Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology https://www.socictopen.socict.org/files/original/31e7b62525a2d3d17db42de3d08e7614.pdf b191d4ddb852352f83114fd7bd7ab54c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Hypertension, Thrombosis, Kidney Failure, and Diabetes: Is COVID-19 an Endothelial Disease? A Comprehensive Evaluation of Clinical and Basic Evidence Creator An entity primarily responsible for making the resource Celestino Sardu, Raffaele Marfella, Marco Bruno Morelli, Xujun Wang, Jessica Gambardella, Gaetano Santulli Description An account of the resource The symptoms most commonly reported by patients affected by coronavirus disease (COVID-19) include cough, fever, and shortness of breath. However, other major events usually observed in COVID-19 patients (e.g., high blood pressure, arterial and venous thromboembolism, kidney disease, neurologic disorders, and diabetes mellitus) indicate that the virus is targeting the endothelium, one of the largest organs in the human body. Herein, we report a systematic and comprehensive evaluation of both clinical and preclinical evidence supporting the hypothesis that the endothelium is a key target organ in COVID-19, providing a mechanistic rationale behind its systemic manifestations. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Blood Pressure, Acute kidney injury, coronavirus, ACE2, Cytokine storm, COVID, catepsin Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/jcm9051417 Source A related resource from which the described resource is derived Journal of Clinical Medicine Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/d9e3b77cada4321ea2977a03423a4682.pdf 2cc9d731e4f6684c7a05d06789d7ac53 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Novel, Inexpensive Portable Respiratory Protection Unit (PRPU) for Healthcare Workers Creator An entity primarily responsible for making the resource Christopher S. Sampson, Adam Beckett Description An account of the resource Introduction: Given concern for increased aerosolization during intubation of patients with severe acute respiratory syndrome coronavirus, we sought to create a portable, inexpensive, and easily constructed device to help protect healthcare workers. Methods: A respiratory protection unit can be constructed in approximately 30 minutes and for less than 50 United States dollars in materials, using polyvinylchloride pipe and automobile collision wrap. Conclusion: This device provides possible increased protection during video laryngoscopy and can easily be replicated. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context DOI: 10.5811/cpcem.2020.4.47443 Source A related resource from which the described resource is derived Clinical Practice and Cases in Emergency Medicine Publisher An entity responsible for making the resource available eScholarship Publishing, University of California Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medical emergencies. Critical care. Intensive care. First aid https://www.socictopen.socict.org/files/original/ec734b1ce9ea47038ad134a1b5349dbf.pdf 79c2d6b2e3064117c0ef851c21e35bb9 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Virus zoonóticos emergentes en un mundo globalizado: SARSCoV- 2/COVID-19 y sus implicaciones en salud pública y en la industria alimentaria Creator An entity primarily responsible for making the resource Francisco José Sánchez-Muniz, María del Rosario Martín de Santos Description An account of the resource - Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource zoonosis, seguridad alimentaria, pandemia, SARS-CoV-2, COVID-19 Identifier An unambiguous reference to the resource within a given context DOI: 10.19230/jonnpr.3741 Source A related resource from which the described resource is derived Jounal of Negative and No Positive Results Publisher An entity responsible for making the resource available Asociación Para el Progreso de la Biomedicina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Science, Medicine https://www.socictopen.socict.org/files/original/bfbf083208dc469d5023b81c81a9c63a.pdf c422646f2727f6765d716b9df92a0d78 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Porcine Epidemic Diarrhea Virus and the Host Innate Immune Response Creator An entity primarily responsible for making the resource Sha-sha Li, Zixiang Zhu, Haixue Zheng, Jinping Yang Description An account of the resource Porcine epidemic diarrhea virus (PEDV), a swine enteropathogenic coronavirus (CoV), is the causative agent of porcine epidemic diarrhea (PED). PED causes lethal watery diarrhea in piglets, which has led to substantial economic losses in many countries and is a great threat to the global swine industry. Interferons (IFNs) are major cytokines involved in host innate immune defense, which induce the expression of a broad range of antiviral effectors that help host to control and antagonize viral infections. PEDV infection does not elicit a robust IFN response, and some of the mechanisms used by the virus to counteract the host innate immune response have been unraveled. PEDV evades the host innate immune response by two main strategies including: (1) encoding IFN antagonists to disrupt innate immune pathway, and (2) hiding its viral RNA to avoid the exposure of viral RNA to immune sensors. This review highlights the immune evasion mechanisms employed by PEDV, which provides insights for the better understanding of PEDV-host interactions and developing effective vaccines and antivirals against CoVs. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Immune Evasion, Innate Immunity, coronavirus, type I IFN, porcine epidemic diarrhea virus Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/pathogens9050367 Source A related resource from which the described resource is derived Pathogens Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/5abb24cadf05f1c030250521dcb1e9b8.pdf 6f7e94dcd315dda2e2526f18b9ef8210 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The challenges facing indigenous communities in Latin America as they confront the COVID-19 pandemic Creator An entity primarily responsible for making the resource Blanca Estela Pelcastre-Villafuerte, Roberto Campos Navarro, Sergio Meneses Navarro, Liliana Gómez-Flores-Ramos, María Graciela Freyermuth Enciso, David Mariano Meléndez-Navarro Description An account of the resource Resumen La pandemia de coronavirus 2019 (COVID-19) golpeó a América Latina a fines de febrero y ahora está comenzando a extenderse por las comunidades indígenas y rurales de la región, hogar de 42 millones de personas. El 80% de esta población altamente marginada se concentra en Bolivia, Guatemala, México y Perú. Los servicios de atención médica para estos grupos étnicos enfrentan desafíos distintos en vista de sus altos niveles de marginación y diferencias culturales de la mayoría. Con más de 30 años de trabajo e investigación sobre las respuestas de los sistemas de salud dirigida a las comunidades indígenas de América Latina, consideramos que los países de la región deben estar preparados para combatir la epidemia en contextos indígenas marcados por la privación y la disparidad social. Discutimos cuatro desafíos principales que deben ser abordados por los gobiernos para garantizar la salud y la vida de los que se encuentran en la parte inferior de la estructura social: los pueblos indígenas de la región. Este análisis proporciona una guía práctica para diseñar e implementar una respuesta a COVID-19 en comunidades indígenas. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Latin America, indigenous populations, COVID-19, Health systems response Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s12939-020-01178-4 Source A related resource from which the described resource is derived International Journal for Equity in Health Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Public aspects of medicine https://www.socictopen.socict.org/files/original/256d544108f4f45820992cb6cae47f1b.pdf 375eb86c90f1c2a7ea42654f3214afe3 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource How the Italian NHS Is Fighting Against the COVID-19 Emergency Creator An entity primarily responsible for making the resource Walter Ricciardi, Stefania Boccia, Martin McKee, Fidelia Cascini Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Italy, emergency, Pandemic, healthcare systems, COVID-19 Identifier An unambiguous reference to the resource within a given context DOI: 10.3389/fpubh.2020.00167 Source A related resource from which the described resource is derived Frontiers in Public Health Publisher An entity responsible for making the resource available Frontiers Media S.A. Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Public aspects of medicine