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                <text>DOI: 10.25237/revchilanestv49n03.018</text>
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                <text>Mará Carolina Cabrera Schulmeyer</text>
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                <text>DOI: 10.25237/revchilanestv49n03.01</text>
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                <text>Revista Chilena de Anestesia</text>
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                <text>Editorial Iku</text>
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                <text>Medicine, Anesthesiology</text>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Finding the Calm in the Chaos: An Institutional Protocol for Anesthetic Management of a Patient for Neurosurgery during Coronavirus  Disease 2019 Pandemic</text>
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            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="31316">
                <text>Thomas Koshy, Manikandan Sethuraman, Unnikrishnan Prathapadas, Neeraja Ajayan, Aishvarya Shree Nedunchezhian, Ajay Prasad Hrishi P.</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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                <text>“Coronavirus disease 2019” (COVID-19) transmitted by a novel coronavirus via contact or droplet spread is a highly infectious disease, the containment of which requires vigilance and stringent infection control policies. In the backdrop of hospitals becoming hot zones and an increasing number of health care workers contracting the disease, it is crucial to formulate an approach while administering anesthesia during the testing times of COVID-19 pandemic. In this background, this comprehensive article deals with the perioperative management during this pandemic and includes risk stratification based on an innovative simple scoring system, rationale use of personal protective equipments, and infection prevention protocols. The document of updated literature, though not intended to replace any guidelines, is aimed at providing protocol to health care workers to protect themselves while providing the best care in this pandemic.</text>
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            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="31318">
                <text>2020</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="31319">
                <text>risk stratification, personal protective equipment, Neuroanesthesia, COVID-19</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="31320">
                <text>DOI: 10.1055/s-0040-1712773</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="31321">
                <text>Journal of Neurosciences in Rural Practice</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="31322">
                <text>Thieme Publishers</text>
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            </elementTextContainer>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Neurosciences. Biological psychiatry. Neuropsychiatry</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Novel Insights Into Illness Progression and Risk Profiles for Mortality in Non-survivors of COVID-19</text>
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              <elementText elementTextId="31325">
                <text>Yi Zhou, Yanan Liu, Xinyi Li, Xinghuan Wang, Fuling Zhou, Minghui LIU, Liang Shao, Haojian Zhang, Ruixian Zhang, Yalan Yu</text>
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            <description>An account of the resource</description>
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                <text>Background. The outbreak of COVID-19 has attracted the attention of the whole world. Our study aimed to describe illness progression and risk profiles for mortality in non-survivors.Methods. We retrospectively analyzed 155 patients with COVID-19 in Wuhan and focused on 18 non-survivors among them. Briefly, we compared the dynamic profile of biochemical and immune parameters and drew an epidemiological and clinical picture of disease progression from disease onset to death in non-survivors. The survival status of the cohort was indicated by a Kaplan–Meier curve.Results. Of the non-survivors, the median age was 73.5 years, and the proportion of males was 72.2%. Five and 13 patients were hospital-acquired and community-acquired infection of SARS-CoV-2, respectively. The interval between disease onset and diagnosis was 8.5 days (IQR, [4–11]). With the deterioration of disease, most patients experienced consecutive changes in biochemical parameters, including lymphopenia, leukocytosis, thrombocytopenia, hypoproteinemia, as well as elevated D-dimer and procalcitonin. Regarding the immune dysregulation, patients exhibited significantly decreased T lymphocytes in the peripheral blood, including CD3+T, CD3+CD4+Th, and CD3+CD8+Tc cells. By the end of the disease, most patients suffered from severe complications, including ARDS (17/18; 94.4%), acute cardiac injury (10/18; 55.6%), acute kidney injury (7/18; 38.9%), shock (6/18; 33.3%), gastrointestinal bleeding (1/18; 5.6%), as well as perforation of intestine (1/18; 5.6%). All patients died within 45 days after the initial hospital admission with a median survivor time of 13.5 days (IQR, 8–17).Conclusions. Our data show that patients experienced consecutive changes in biochemical and immune parameters with the deterioration of the disease, indicating the necessity of early intervention.</text>
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                <text>2020</text>
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                <text>disease progression, SARS-CoV-2, COVID-19, non-survivor, complete clinical course</text>
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                <text>DOI: 10.3389/fmed.2020.00246</text>
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              <elementText elementTextId="31330">
                <text>Frontiers in Medicine</text>
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              <elementText elementTextId="31331">
                <text>Frontiers Media S.A.</text>
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                <text>Medicine (General)</text>
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