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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Rapid guide to the management of cardiac patients during the COVID-19 pandemic in Egypt: “a position statement of the Egyptian Society of Cardiology”</text>
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                <text>Magdy AbdelHamid, Adel El Etriby, Khalid Shokry, Hamza Kabil, Omar Awwad, Amr El Hadidy, Sameh Shaheen, Hsam Hasan-Ali, Islam Shawky, Ahmad Magdy, Gamila Nasr, Mohamad Zaki, Ahmad Hegab</text>
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                <text>Abstract COVID-19 pandemic poses an enormous challenge to healthcare system in Egypt. This document is a position statement from the Egyptian Society of Cardiology. It aims to provide information to cardiovascular healthcare providers in Egypt to guarantee delivery of quality patient care and ensure adequate levels of protection against infection during the COVID-19 pandemic. Older patients and those with cardiovascular disease are at higher risk of mortality. The current situation requires unusual allocation of resources which may negatively impact the care of patients with cardiovascular disease. Cardiologists should be prepared in the COVID-19 pandemic. The challenge is in providing the best quality of care despite limited resources while keeping all medical staff as safe as possible. Consider deferring elective procedures whenever possible. All medical staff should undergo rigorous training on infection control and the use of high-quality personal protection equipment. Cardiologists should promote telemedicine in the outpatient setting, prioritize outpatient contacts, and avoid nosocomial dissemination of the virus to patients and healthcare providers. A much conservative approach for emergent cardiac patients is recommended, and invasive interventions are reserved for high risk hemodynamically unstable patients. During the pandemic, the most important principles of treatment should be controlling the spread of infection as the first priority, prompt assessment of patient risk, recommending conservative medical therapy rather than invasive interventions, and strict infection control measures to limit infection spread within the hospital and to healthcare workers.</text>
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                <text>2020</text>
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                <text>Cardiovascular disease, Egypt, Pandemic, COVID-19</text>
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                <text>DOI: 10.1186/s43044-020-00061-5</text>
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                <text>The Egyptian Heart Journal</text>
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                <text>SpringerOpen</text>
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                <text>Diseases of the circulatory (Cardiovascular) system</text>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Nanomaterials and Nanotechnology-Associated Innovations against Viral Infections with a Focus on Coronaviruses</text>
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                <text>Rajender S. Varma, Mahmoud Nasrollahzadeh, Mohaddeseh Sajjadi, Siavash Iravani, Ghazaleh  Jamalipour Soufi</text>
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                <text>Viral infections have recently emerged not only as a health threat to people but rapidly became the cause of universal fatality on a large scale. Nanomaterials comprising functionalized nanoparticles (NPs) and quantum dots and nanotechnology-associated innovative detection methods, vaccine design, and nanodrug production have shown immense promise for interfacing with pathogenic viruses and restricting their entrance into cells. These viruses have been scrutinized using rapid diagnostic detection and therapeutic interventional options against the caused infections including vaccine development for prevention and control. Coronaviruses, namely SARS-CoV, MERS-CoV, and SARS-CoV-2, have endangered human life, and the COVID-19 (caused by SARS-CoV-2) outbreak has become a perilous challenge to public health globally with huge accompanying morbidity rates. Thus, it is imperative to expedite the drug and vaccine development efforts that would help mitigate this pandemic. In this regard, smart and innovative nano-based technologies and approaches encompassing applications of green nanomedicine, bio-inspired methods, multifunctional bioengineered nanomaterials, and biomimetic drug delivery systems/carriers can help resolve the critical issues regarding detection, prevention, and treatment of viral infections. This perspective review expounds recent nanoscience advancements for the detection and treatment of viral infections with focus on coronaviruses and encompasses nano-based formulations and delivery platforms, nanovaccines, and promising methods for clinical diagnosis, especially regarding SARS-CoV-2.</text>
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                <text>2020</text>
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                <text>nanoparticles, nanotechnology, graphene oxide, coronaviruses, quantum dots, nanovaccines</text>
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                <text>DOI: 10.3390/nano10061072</text>
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                <text>Nanomaterials</text>
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                <text>MDPI AG</text>
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                <text>Chemistry</text>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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            <description>A name given to the resource</description>
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                <text>Use of non-invasive ventilation in acute respiratory failure due to SARS-CoV-2 pneumonia: typing of patients and choice of respiratory support, the role of internal medicine</text>
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              <elementText elementTextId="32132">
                <text>Federico Lari, Fabrizio Giostra, Stefania Guerrini</text>
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            <description>An account of the resource</description>
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              <elementText elementTextId="32133">
                <text>The use of non-invasive ventilation (NIV) during de novo acute hypoxemic respiratory failure is not recommended by the guidelines because NIV does not improve the prognosis. With the advent of the new coronavirus, many cases of acute hypoxemic respiratory failure associated with the infection (severe acute respiratory infection) have been observed: data are missing regarding the use of NIV in this particular clinical condition, but a correct typing of patients based on different clinical, pathophysiological and radiological characteristics, could help in prognostic stratification and in the choice of respiratory support (invasive versus non-invasive). During NIV in these patients particular attention is paid to the possibility of environmental dissemination of the virus and consequently adequate technical precautions are taken.</text>
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                <text>2020</text>
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                <text>acute respiratory failure, Noninvasive ventilation, SARS-CoV-2</text>
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              <elementText elementTextId="32136">
                <text>DOI: 10.4081/itjm.2020.1309</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="32137">
                <text>Italian Journal of Medicine</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>PAGEPress Publications</text>
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                <text>Medicine</text>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>A Simulation of a COVID-19 Epidemic Based on a Deterministic SEIR Model</text>
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                <text>José M. Carcione, Juan E. Santos, Claudio Bagaini, Jing Ba</text>
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                <text>An epidemic disease caused by a new coronavirus has spread in Northern Italy with a strong contagion rate. We implement an SEIR model to compute the infected population and the number of casualties of this epidemic. The example may ideally regard the situation in the Italian Region of Lombardy, where the epidemic started on February 24, but by no means attempts to perform a rigorous case study in view of the lack of suitable data and the uncertainty of the different parameters, namely, the variation of the degree of home isolation and social distancing as a function of time, the initial number of exposed individuals and infected people, the incubation and infectious periods, and the fatality rate. First, we perform an analysis of the results of the model by varying the parameters and initial conditions (in order for the epidemic to start, there should be at least one exposed or one infectious human). Then, we consider the Lombardy case and calibrate the model with the number of dead individuals to date (May 5, 2020) and constrain the parameters on the basis of values reported in the literature. The peak occurs at day 37 (March 31) approximately, with a reproduction ratio R0 of 3 initially, 1.36 at day 22, and 0.8 after day 35, indicating different degrees of lockdown. The predicted death toll is approximately 15,600 casualties, with 2.7 million infected individuals at the end of the epidemic. The incubation period providing a better fit to the dead individuals is 4.25 days, and the infectious period is 4 days, with a fatality rate of 0.00144/day [values based on the reported (official) number of casualties]. The infection fatality rate (IFR) is 0.57%, and it is 2.37% if twice the reported number of casualties is assumed. However, these rates depend on the initial number of exposed individuals. If approximately nine times more individuals are exposed, there are three times more infected people at the end of the epidemic and IFR = 0.47%. If we relax these constraints and use a wider range of lower and upper bounds for the incubation and infectious periods, we observe that a higher incubation period (13 vs. 4.25 days) gives the same IFR (0.6 vs. 0.57%), but nine times more exposed individuals in the first case. Other choices of the set of parameters also provide a good fit to the data, but some of the results may not be realistic. Therefore, an accurate determination of the fatality rate and characteristics of the epidemic is subject to knowledge of the precise bounds of the parameters. Besides the specific example, the analysis proposed in this work shows how isolation measures, social distancing, and knowledge of the diffusion conditions help us to understand the dynamics of the epidemic. Hence, it is important to quantify the process to verify the effectiveness of the lockdown.</text>
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                <text>2020</text>
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                <text>epidemic, SEIR model, COVID-19, lockdown, infection fatality rate (IFR), reproduction ratio (R0)</text>
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                <text>DOI: 10.3389/fpubh.2020.00230</text>
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                <text>Frontiers in Public Health</text>
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                <text>Frontiers Media S.A.</text>
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                <text>Public aspects of medicine</text>
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                <text>Jurnal Sosiologi Reflektif volume 14 nomor 2, April 2020  ini mengkaji permasalahan sosial yang kompleks dalam perspektif sosiologis. Kajian yang ditulis dalam edisi ini spesifik pada isu pariwisata dan kuliner yang menjadi booming dalam beberapa waktu lalu sebelum terjadinya pandemi covid-19 dan satu artikel tentang peranan media facebook dalam mengembangkan komunitas merek UMKM di Yogyakarta.</text>
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                <text>Islam, Sociology (General)</text>
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                <text>Abstract Introduction The coronavirus disease (COVID-19) pandemic has placed enormous pressures on the Canadian healthcare system. Patients are expected to stay home in order to contain the spread of the virus, but understandably have numerous questions and concerns about their health. With physical distancing being of utmost importance during the pandemic, much of healthcare has been forced to move online or over the telephone. Virtual healthcare, in the form of video calls, email, or telephone calls with patients, can significantly enhance access to healthcare. Many clinics have moved their appointments online, and physicians are seeing their patients by means of online video calls. Similarly, patients are refilling their prescriptions online and calling pharmacists whenever they have questions about their medications or medical conditions. Pharmacists are considered the most accessible primary care providers, so it is crucial for patients to know that pharmacists are there to support them throughout the pandemic.</text>
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                <text>Current Speculations on the Low Incidence Rate of the COVID-19 among Children</text>
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                <text>Shakhawan M. Ali, Dana Khdr Sabir, Karzan R Sidiq</text>
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                <text>Children, Immunization, vaccination, Immunity, SARS-CoV-2, COVID-19</text>
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                <text>DOI: 10.30476/intjsh.2020.85997.1066</text>
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                <text>International Journal of School Health</text>
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                <text>Shiraz University of Medical Sciences</text>
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