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                <text>Threat of Dengue Outbreak in Nepal in Context of COVID-19 Pandemic</text>
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                <text>Dipesh Tamrakar, Pallavi Koirala</text>
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                <text>The world has been chained with Corona Virus Disease (COVID-19) pandemic today. It has affected more than 200 countries in just about a few months since December 2019. The virus has engulfed the world at a momentum never seen before. Considering the chances of disease being spread through asymptomatic transmission, social distancing has become a norm. This has brought a huge shift in how we live, work or interact with each other. It is feared that after the pandemic is over, the world would suffer a period of economic loss, as huge as the greatest depression of the 1930s or even more. With the world making medieval inventions and science doing wonders, we seem helpless to fight this pandemic. It has also drawn us to a realization that pandemic response cannot be extemporaneous.</text>
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                <text>Dengue, Nepal, COVID-19</text>
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                <text>DOI: 10.22502/jlmc.v8i1.365</text>
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                <text>Journal of Lumbini Medical College</text>
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                <text>The COVID-19 Cytokine Storm; What We Know So Far</text>
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                <text>Mohamed Taeimah, Dina Ragab, Haitham Salah Eldin, Rasha Khattab, Ramy Salem</text>
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                <text>COVID-19 is a rapidly spreading global threat that has been declared as a pandemic by the WHO. COVID-19 is transmitted via droplets or direct contact and infects the respiratory tract resulting in pneumonia in most of the cases and acute respiratory distress syndrome (ARDS) in about 15 % of the cases. Mortality in COVID-19 patients has been linked to the presence of the so-called “cytokine storm” induced by the virus. Excessive production of proinflammatory cytokines leads to ARDS aggravation and widespread tissue damage resulting in multi-organ failure and death. Targeting cytokines during the management of COVID-19 patients could improve survival rates and reduce mortality.</text>
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                <text>cytokine, IL-6, storm, ARDS, COVID-19</text>
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                <text>DOI: 10.3389/fimmu.2020.01446</text>
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                <text>Frontiers in Immunology</text>
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                <text>Frontiers Media S.A.</text>
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                <text>Immunologic diseases. Allergy</text>
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                <text>Editorial Preface: Covid-19 vs City-20</text>
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                <text>Carmela Gargiulo</text>
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                <text>DOI: 10.6092/1970-9870/6985</text>
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                <text>TeMA: Journal of Land Use, Mobility and Environment</text>
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                <text>Università di Napoli Federico II</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Transportation engineering, Urbanization. City and country</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Questioning urbanisation models in the face of Covid-19</text>
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                <text>Giancarlo Cotella, Elisabetta Vitale Brovarone</text>
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                <text>The COVID-19 pandemic raises questions on the ever-growing urban concentration that characterizes our society and various experts are pointing out the need to rethink our cities. At the same time, a number of voices advocate for a rediscovery of the rural. However naive they may sound, these claims have the merit to call for a thorough reflection on the challenges and potentials that alternative modes of urbanisation could bring along. In order to provide a contribution in this direction, the article introduces the challenges that the present sanitary emergency raises for contemporary urban environments, to then reflect on the reasons behind the progressive abandonment of remote rural areas, and especially on the increasingly scarce accessibility to services they offer to their inhabitants. The authors argue that policies dedicated to counteract these trends are needed, in order to enhance the overall resilience of our societies. In this concern, the National Strategy for Inner Areas, promoted by the Italian Government to trigger place-based territorial development in the remote areas of the country, is a promising way forward, and the present crisis constitutes a window of opportunity to further strengthen and refine its approach in the view of the coming EU programming period.</text>
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                <text>2020</text>
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                <text>rural development, urbanization, EU cohesion policy, COVID-19, national strategy for inner areas</text>
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                <text>DOI: 10.6092/1970-9870/6913</text>
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                <text>TeMA: Journal of Land Use, Mobility and Environment</text>
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                <text>Università di Napoli Federico II</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Transportation engineering, Urbanization. City and country</text>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Health emergency and economic and territorial implications. First considerations</text>
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                <text>Giuseppe Mazzeo, Salvatore Capasso</text>
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                <text>The Covid-19 epidemic has caused a lot of economic and social damages and has generated territorial imbalances that are not yet quantifiable. Many research groups are currently committed to deepen their understanding of the impact of the crisis using different disciplinary methodologies and focusing on different aspects of the phenomenon. These researches reveal causal links between the variables involved that have not been explored up until now and raise relevant questions for the economic and social future of our Country. This paper wants to provide an overview of the territorial and economic implications related to the epidemic event on the basis of a set of economic, settlement and environmental indicators applied to the two territorial dimensions of the Italian Regions and Provinces. For each of them, the connection with primary epidemic data (number of cases and number of deaths) was analysed to verify the possible presence and consistency of the correlation indices. Aim of the article is to highlight some territorial characteristics that may have facilitated the spread of the epidemic by identifying, at the same time, some actions that will positively affect them, in an evolutionary perspective.</text>
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                <text>2020</text>
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                <text>urban planning, economy, geographical data analysis, post-covid actions</text>
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                <text>DOI: 10.6092/1970-9870/6866</text>
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                <text>Transportation engineering, Urbanization. City and country</text>
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                <text>Covid-19. Some moments of the 21st century, with a look at Milan</text>
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                <text>Roberto Busi</text>
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                <text>Critically narrating some impacts on the civitas and urbs of the pandemic, the paper argues how the relative pathos of death and poverty unleashed on Milan is, in fact, a contingency on the endless flux of the urban body in the long history of the city. The text, divided into five paragraphs - then (May 2019), yesterday (March 2020), today (April 2020), tomorrow (May 2020) and later (May 2030) -, in addition to the bibliography, develops as in a Gaussian curve, the two extremes being (“then” and “later”) in points before and after the beginning of the curvature, respectively (i.e., describing situations “at full throttle”), the centre (“today”) the peak of the curve and the two intermediates (“yesterday” and “tomorrow”) in its ascending and descending sections, respectively. The style varies from calmness at the extremes (with mainly hypotactic periods) to the unease of the intermediates, namely, at its peak (with mainly paratactic periods).</text>
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                <text>catastrophe, permanence, metropolis, Milán</text>
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                <text>DOI: 10.6092/1970-9870/6858</text>
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                <text>Università di Napoli Federico II</text>
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                <text>Transportation engineering, Urbanization. City and country</text>
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                <text>Geographical analyses of Covid-19's spreading contagion in the challenge of global health risks</text>
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                <text>Beniamino Murgante, Giuseppe Borruso, Ginevra Balletto, Paolo Castiglia, Marco Dettori, Giuseppe Las Casas</text>
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                <text>This research develops from a set of basic geographical questions about the outbreak of Covid-19 out of China in Europe. The questions dealt with why and why with such strength Italy has been seriously hit, one of the most important cases in terms of death toll out of Hubei Province and mainland China, in the world, making the country a worldwide study case for epidemic concentration and diffusion. Questions were also related to geographical similarities among the areas hit, and particularly the Po Valley region and Wuhan metropolitan region in Hubei province, and also related to why such a divide of the virus spreading was identified in Italy between Northern and Central and Southern regions and provinces. In order to try to give an answer these questions, authors realized a vast and articulated database of indicators at provincial level in Italy, performing several geographical analyses - ecological approach - based on Spatial autocorrelation and Geographical Weighted Regression, coming to the conclusion that aspects such as land take, pollution can seriously influence the phenomenon and justify a pattern as that observable in Italy. The analyses and observation of the phenomenon also suggests that policies based on urban regeneration, sustainable mobility, green infrastructures, ecosystem services can create a more sustainable scenario able to support the quality of public health.</text>
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                <text>DOI: 10.6092/1970-9870/6849</text>
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                <text>TeMA: Journal of Land Use, Mobility and Environment</text>
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                <text>Università di Napoli Federico II</text>
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              <elementText elementTextId="36752">
                <text>Transportation engineering, Urbanization. City and country</text>
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                <text>The Covid-19 pandemic effects in rural areas</text>
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                <text>Simona Tondelli, Claudia de Luca, Hanna Elisabeth Åberg</text>
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                <text>Rural communities tell us the story of a thousand of years of collaboration between nature, culture and humans. The current COVID-19 pandemic is considerably threating rural areas, posing challenges exacerbated by low available financial resources, not easily accessible health services and greater isolation. Rural areas are also considered safe shelters characterized by better daily living conditions thanks to easy to maintain social distancing and access to nature, to cultural and nature-based recreation activities. The COVID-19 crisis is revealing the crucial role of natural and cultural heritage for social cohesion, local development and mental wellbeing. The paper presents some responses to the COVID-19 crisis collected through an open call for action within the RURITAGE project. It aims at show how rural areas can cope with emergencies and it builds the basis to rethink the current crisis as a crucial tipping point for a resilient development of rural territories. It is key to overcome the idea of rural areas as mere food production system, calling for a broader vision of rural communities as poles of development based on local heritage, natural resources, creativity and social inclusion as essential elements to regenerate rural areas and to rapidly support their transition towards sustainable future.</text>
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                <text>2020</text>
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                <text>social resilience, COVID-19, rural regeneration</text>
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                <text>DOI: 10.6092/1970-9870/6844</text>
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            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="36759">
                <text>TeMA: Journal of Land Use, Mobility and Environment</text>
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            <name>Publisher</name>
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              <elementText elementTextId="36760">
                <text>Università di Napoli Federico II</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Transportation engineering, Urbanization. City and country</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Immune Status of COVID-19 Patients with Reference to SARS and MERS</text>
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                <text>Barani Karikalan, Hari Kumar Darnal</text>
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                <text>During this global pandemic of COVID-19 infection, it became well known that morbidity and mortalityis especially high at the extreme of life especially in certain racial or ethnic groups like Americansand Africans. This is presumed due to low immunity associated with other comorbid conditions likediabetes, hypertension, cardiovascular disease, obesity and metabolic syndrome. But the informationavailable on the immune status of COVID-19 patients is limited. Attempts must be made to enhanceour understanding of the immune status of COVID-19 patients by revisiting our knowledge on theimmune mechanisms of already known coronaviruses such as SARS-CoV and MERS-CoV. Early elevationof the serum levels of pro-inflammatory cytokines observed in SARS and MERS infection suggests apossible same type of cytokine storm-mediated lung damage in COVID-19 patients too. Dysregulationof interferon-1 response and downstream cascade in initial innate immune response at virus entrypoint has been related to lethal pneumonia in COVID-19 patients. Adaptive response of increasedCD8+ levels in COVID-19 patients seems to be useful in mild cases where it causes deterioratingeffects in progressed severe disease patients resulting in destruction of type 2 pneumocytes henceinability to regenerate the alveolar epithelium. A phenomenon called cytokine storm activates violentimmunological reactions in the lung tissue resulting in ARDS followed by multiple organ systemdamages in COVID-19 patients. Several immune evading mechanisms are thought to be employed bysevere respiratory syndrome virus-2 (SARS-CoV-2) that might have resulted in its extremely increasedcontagiousness probably related with its frequent RNA mutations. Failure to develop adequate viruslimiting immune reactions by some cured patients warrant monitoring of all recovered patients. Thisrapid mini review is aimed to enhance our knowledge of the immune status of COVID-19 infectedpatients with reference to SARS-CoV and MERS-CoV.</text>
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                <text>2020</text>
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            <name>Subject</name>
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                <text>coronavirus, MERS-CoV, Immune status, SARS-CoV, COVID-19</text>
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            <name>Identifier</name>
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              <elementText elementTextId="36767">
                <text>DOI: 10.22207/JPAM.14.SPL1.18</text>
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              <elementText elementTextId="36768">
                <text>Journal of Pure and Applied Microbiology</text>
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            <name>Publisher</name>
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              <elementText elementTextId="36769">
                <text>Journal of Pure and Applied Microbiology</text>
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                <text>Microbiology</text>
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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Keep Healthcare Workers Safe: Application of Teleoperated Robot in Isolation Ward for COVID-19 Prevention and Control</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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                <text>Liu Yang, Juan Du, Geng Yang, Jia Deng, Zhiyu Zhang, Honghao Lv, Huayong Yang, Siqi You</text>
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                <text>2020</text>
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                <text>DOI: 10.1186/s10033-020-00464-0</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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                <text>Chinese Journal of Mechanical Engineering</text>
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          <element elementId="45">
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                <text>SpringerOpen</text>
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                <text>Ocean engineering, Mechanical engineering and machinery</text>
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