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                  <text>Dominio científico: Coronavirus</text>
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                <text>An Extensive Search Trends-Based Analysis of Public Attention on Social Media in the Early Outbreak of COVID-19 in China</text>
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                <text>Xie T, Tan T, Li J</text>
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                <text>Tiantian Xie,1 Tao Tan,2 Jun Li3,4 1Centre De Recherche Sur Les Liens Sociaux (CERLIS), Paris Descartes University, Paris, France; 2Institute of New Rural Development, South China Agricultural University, Guangzhou, People&amp;rsquo;s Republic of China; 3School of International Relations, Sun Yat-Sen University, Guangzhou, People&amp;rsquo;s Republic of China; 4School of Management, Curtin University, Perth, WA, AustraliaCorrespondence: Tiantian Xie Tel +33-651-837-168Email tiantian.xie@etu.parisdescartes.frBackground: A novel coronavirus (COVID-19) caused pneumonia broke out at the end of 2019 in Wuhan, China. Many cases were subsequently reported in other cities, which has aroused strong reverberations on the Internet and social media around the world.Objective: The aim of this study was to investigate the reaction of global Internet users to the outbreak of COVID-19 by evaluating the possibility of using Internet monitoring as an instrument in handling communicable diseases and responding to public health emergencies.Methods: The disease-related data were retrieved from China&amp;rsquo;s National Health Commission (CNHC) and World Health Organization (WHO) from January 10 to February 29, 2020. Daily Google Trends (GT) and daily Baidu Attention Index (BAI) for the keyword &amp;ldquo;Coronavirus&amp;rdquo; were collected from their official websites. Rumors which occurred in the course of this outbreak were mined from Chinese National Platform to Refute Rumors (CNPRR) and Tencent Platform to Refute Rumors (TPRR). Kendall&amp;rsquo;s Tau-B rank test was applied to check the bivariate correlation among the two indexes mentioned above, epidemic trends, and rumors.Results: After the outbreak of COVID-19, both daily BAI and daily GT increased rapidly and remained at a high level, this process lasted about 10 days. When major events occurred, daily BAI, daily GT, and the number of rumors simultaneously reached new peaks. Our study indicates that these indexes and rumors are statistically related to disease-related indicators. Information symmetry was also found to help significantly eliminate the false news and to prevent rumors from spreading across social media through the epidemic outbreak.Conclusion: Compared to traditional methods, Internet monitoring could be particularly efficient and economical in the prevention and control of epidemic and rumors by reflecting public attention and attitude, especially in the early period of an outbreak.Keywords: public attention, COVID-19, internet monitoring, search index</text>
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                <text>2020</text>
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                <text>covid-19, public attention, internet monitoring, search index</text>
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                <text>Biotemas</text>
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                <text>Universidade Federal de Santa Catarina</text>
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                <text>Public aspects of medicine</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Beyond COVID-19: Turning  Crisis to Opportunity in Nigeria through Urban Agriculture</text>
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                <text>Adeniyi Gbadegesin, Bolanle Olajiire-Ajayi</text>
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                <text>First paragraph:  Since the outbreak of the novel coronavirus (COVID-19) all over the world, countries have tried several strategies to minimize its impacts on their citizens and the economy. The first case in Nigeria was reported on February 27, 2020, and since then the infection has been spreading like wildfire, making Nigeria one of the three most affected African countries in Africa and the most affected in West Africa (Food and Agriculture Organization of the United Nations [FAO], 2020-a). To slow down its pace, governments at all levels have taken measures to curb its impacts. Measures taken include mandating social distancing, curfews, and, in some cases, complete lockdowns. The lockdown of virtually all sectors of the economy, especially the agricultural sector, has exacerbated food shortages in the country, espe­cially among urban dwellers. Unfortunately, agriculture in most developing countries is highly related to physical, rather than mechanized, labor. The labor shortage due to movement restrictions (both intra- and interstate) and social distancing as a result of COVID-19 are starting to affect agricultural producers in the hinterlands, thus worsening the food supply to urban centers that are coincidentally the epicenters of the disease.</text>
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                <text>2020</text>
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                <text>covid-19, Pandemic, food security, Nigeria, urban agriculture</text>
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                <text>10.5304/jafscd.2020.094.033</text>
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                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Agriculture, Environmental sciences, Geography. Anthropology. Recreation, Technology, Social Sciences, Nutrition. Foods and food supply, Recreation. Leisure, Urban groups. The city. Urban sociology, Regional planning, Communities. Classes. Races, Human ecology. Anthropogeography, Home economics</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Emphasizing the role of youth in the battle against COVID-19 pandemic</text>
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                <text>Saurabh RamBihariLal Shrivastava, Prateek Saurabh Shrivastava</text>
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                <text>The ongoing Corona Virus Disease-2019 (COVID-19) pandemic has impacted the lives of the population from all age-groups and the effects have been way beyond the health dimension. Even though, the initial treatment outcomes have suggested that elderly people are more at risk to develop severe forms of the disease, but it is important to remember that even the younger people are not spared from the infection. In-fact, the epidemiological data obtained from most of the nations has revealed that people less than 50 years of age constitute a significant share of the patients. As it is a well-known fact that no nation or community or individual is immune to the infection, in these challenging times, each and every section of society, including the young people, should take adequate steps to restore their physical and mental well-being. In conclusion, the support of young people in minimizing the spread of the COVID-19 infection is extremely crucial and they should extend their complete support and adhere to the national recommendations in these difficult times of COVID-19 pandemic.</text>
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                <text>2020</text>
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                <text>World Health Organization;, covid-19 pandemic, YOUNG PEOPLE</text>
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                <text>10.4103/jss.JSS_40_20</text>
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                <text>Biotemas</text>
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                <text>Universidade Federal de Santa Catarina</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Medicine</text>
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                <text>Cutaneous Complications Secondary to Haemostasis Abnormalities in COVID-19 Infection</text>
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                <text>Noel Lorenzo Villalba, Abrar-Ahmad Zulfiqar, Yasmine Maouche, Aneska Syrovatkova, Felix Pham, Jean-Baptiste Chahbazian, Pierre Pertoldi, Emmanuel Andrès</text>
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                <text>We describe the case of a patient hospitalized for acute decompensated heart failure in a standard medical ward. During hospitalization, he was diagnosed with COVID-19 and transferred to a special unit. The clinical course was marked by worsening of the respiratory disease, the development of right parotiditis and thrombosis of the left internal jugular vein. Therapeutic anticoagulation was initiated and 2 days later, the minimal dermatoporosis lesions previously present in the upper extremities evolved to haemorrhagic bullae with intra-bullae blood clots and dissecting haematomas. Surgical management of the dissecting haematomas was difficult in the context of haemostasis abnormalities. The patient died 29 days after hospital admission.</text>
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                <text>covid-19, coagulation abnormalities, Dermatoporosis, dissecting haematoma</text>
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                <text>10.12890/2020_001769</text>
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                <text>Korean Society of Epidemiology</text>
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            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="45915">
                <text>COVID-19, Chronic Obstructive Pulmonary Disease and Pneumothorax:  A Frightening Triad</text>
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            </elementTextContainer>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="45916">
                <text>Erika Poggiali, Andrea Vercelli, Teresa Iannicelli, Valentina Tinelli, Laura Celoni, Andrea Magnacavallo</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="45917">
                <text>We describe the case of a male patient admitted to our emergency department during the Italian COVID-19 epidemic, for progressive worsening dyspnoea. A diagnosis of pneumothorax and diffuse interstitial lung involvement was promptly made by lung ultrasound and confirmed by an HRCT scan. A chest CT scan also showed diffuse emphysema, as observed in chronic obstructive pulmonary disease (COPD), and small consolidations in the lower lobes, suggestive for COVID-19 pneumonia. A chest tube was immediately inserted in the emergency room with complete resolution of the dyspnoea. A nasopharyngeal swab for 2019-nCoV was positive. Unfortunately, the patient died from COVID-19-related acute respiratory distress syndrome after 48 days of hospitalization.</text>
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            <name>Date</name>
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              <elementText elementTextId="45918">
                <text>2020</text>
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            </elementTextContainer>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="45919">
                <text>covid-19, pneumonia, COPD, ARDS, Pneumothorax, Dyspnoea</text>
              </elementText>
            </elementTextContainer>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="45920">
                <text>10.12890/2020_001742</text>
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            </elementTextContainer>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="45921">
                <text>Epidemiology and Health</text>
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            </elementTextContainer>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="45922">
                <text>Korean Society of Epidemiology</text>
              </elementText>
            </elementTextContainer>
          </element>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Medicine</text>
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            </elementTextContainer>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                <elementText elementTextId="1">
                  <text>Coronavirus</text>
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              </elementTextContainer>
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              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>COVID-19 Presenting as Acute Limb Ischaemia</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="45925">
                <text>Parminder Kaur, Sahitya Posimreddy, Balraj Singh, Firas Qaqa, Habib A Habib, Michael Maroules, Fayez Shamoon</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="45926">
                <text>The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic that developed in late 2019 and early 2020 has caused thousands of deaths and has had an enormous impact on our health systems and economies. Coronavirus disease 2019 (COVID-19) complications include disseminated coagulation and thrombosis, but, to the best of our knowledge, the literature to date on these manifestations has been limited. Herein, we report an unusual presentation in a 43-year-old man with a medical history of diabetes and hypertension who presented with dyspnoea and acute pain in his right leg and was found to have acute limb ischaemia and diabetic ketoacidosis. Our case adds to the literature regarding arterial thrombosis in COVID-19.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="45927">
                <text>2020</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="45928">
                <text>covid-19, severe acute respiratory syndrome coronavirus 2, arterial thrombosis</text>
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            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="45929">
                <text>10.12890/2020_001724</text>
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            </elementTextContainer>
          </element>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="45930">
                <text>Epidemiology and Health</text>
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            </elementTextContainer>
          </element>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="45931">
                <text>Korean Society of Epidemiology</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="45932">
                <text>Medicine</text>
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            </elementTextContainer>
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  <item itemId="5116" public="1" featured="0">
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      <file fileId="5116">
        <src>https://www.socictopen.socict.org/files/original/0e974c4da28647f3e84581a24147f26f.pdf</src>
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          <elementContainer>
            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="1">
                  <text>Coronavirus</text>
                </elementText>
              </elementTextContainer>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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              </elementTextContainer>
            </element>
          </elementContainer>
        </elementSet>
      </elementSetContainer>
    </collection>
    <itemType itemTypeId="1">
      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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    <elementSetContainer>
      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
        <elementContainer>
          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="45933">
                <text>Considerations for Treating Corona Virus (Sars-Cov-2) Infection with Passive Immunotherapy</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="45934">
                <text>Abraham  Karpas, Douglas Bainbridge, Stephen  Ash</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="45935">
                <text>The corona viruses are transient RNA viruses; once an infected individual recovers he or she becomes virus-free and immune. One could expect that in SARS-Covid-19 also, infected individuals who recover will have developed some form of protective immunity. Very little is yet known about its development, when and for how long it might last, and though it is very likely to involve virus-neutralising antibodies, to what extent it might depend on the appearance of such antibodies. However in a recent report 10 very advanced corona patients were treated with a single 200 ml dose of plasma obtained from individuals recovered from the infection. There was impressive clinical improvement.</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="45936">
                <text>2020</text>
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            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="45937">
                <text>coronavirus, covid-19, SARS-CoV-2, Immunotherapy, emergency</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="45938">
                <text>10.13128/Substantia-924</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="45939">
                <text>Epidemiology and Health</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="45940">
                <text>Korean Society of Epidemiology</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="45941">
                <text>Chemistry, History (General) and history of Europe</text>
              </elementText>
            </elementTextContainer>
          </element>
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  <item itemId="5117" public="1" featured="0">
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      <file fileId="5117">
        <src>https://www.socictopen.socict.org/files/original/b71a3fc073e2b19f5dd5dbc82b334296.pdf</src>
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          <name>Dublin Core</name>
          <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
          <elementContainer>
            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="1">
                  <text>Coronavirus</text>
                </elementText>
              </elementTextContainer>
            </element>
            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
                </elementText>
              </elementTextContainer>
            </element>
          </elementContainer>
        </elementSet>
      </elementSetContainer>
    </collection>
    <itemType itemTypeId="1">
      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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    <elementSetContainer>
      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
        <elementContainer>
          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="45942">
                <text>Self-Organisation in Lifelong Learning: Theory, Practice and Implementation Experience Involving Social Networks and a Remote Format</text>
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          </element>
          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="45943">
                <text>Iosif Sandor, Mario De Martino, Yulia Sh. Gushchina, Zlata V. Boyko, Angela Magnanini, Berta Alicia Guerrero Perez, Emanuele Isidori</text>
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            </elementTextContainer>
          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="45944">
                <text>Currently, in the context of the global transition of the world education system to the remote format, it has become vitally important for a person to be able and ready to independently organise his/her educational and professional activities. The article considers methodological approaches to self-education in the context of its use in the process of lifelong learning/ continuous education. The authors discuss the existing concepts of self-education and ways of its organisation, taking into account age-specific features, forms and types of learning. The concepts of ‘self-organisation’ and ‘self-education’ are analysed. The essence of the scientific categories ‘self-learning’ and ‘self-organisation in education’ is revealed in relation to the system of higher education. The role of tutors as mediators in student self-organisation is shown and their main functions in this process are described. Based on a theoretical analysis of existing forms of self-organisation in education and the experience of using self-organisation, various directions and possibilities of their application in practice are delineated. Careful consideration is given to criticism of the use of self-organisation in learning and its advantages. The authors also discuss the prospects of using self-organisation in higher education, emphasising the importance and relevance of developing self-organisation as a student’s personality trait. A description is made of learning models based on self-organisation of students. Finally, the experience of implementing the self-organisation approach to the educational process is analysed. As a result of the study, the authors conclude that self-learning can be successful if it seems socially significant for students. The use of advanced digital technologies and Internet resources can also contribute to effective self-learning. The results of the study indicate that students should develop the ability to independently organise their educational activities as well as self-control/self-assessment skills, which is especially important in connection with the increase in independent work in curricula and the massive transition to the remote format in higher education during the COVID-19 pandemic.</text>
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          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="45945">
                <text>2020</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="45946">
                <text>lifelong learning, remote education, social network, Continuing Education, self-education, self-organisation of students</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="45947">
                <text>10.22363/2313-1683-2020-17-3-373-389</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="45948">
                <text>RUDN Journal of Psychology and Pedagogics</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="45949">
                <text>Peoples’ Friendship University of Russia (RUDN University)</text>
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            </elementTextContainer>
          </element>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="45950">
                <text>Psychology, Education</text>
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  <item itemId="5118" public="1" featured="0">
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        <src>https://www.socictopen.socict.org/files/original/a663efbbcdc358431dc78b1ff7e9cbb5.pdf</src>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="1">
                  <text>Coronavirus</text>
                </elementText>
              </elementTextContainer>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
                </elementText>
              </elementTextContainer>
            </element>
          </elementContainer>
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      </elementSetContainer>
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    <itemType itemTypeId="1">
      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="45951">
                <text>Three Novel COVID-19 Pneumonia Cases Successfully Treated With Lopinavir/Ritonavir</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="45952">
                <text>Tatsuhiko Wada, Kosuke Shimode, Takayuki Hoshiyama, Takayuki Hoshiyama, Yoko Takayama, Kunihiro Yamaoka</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="45953">
                <text>Following the first case of Coronavirus Disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-Cov-2), in Wuhan, China, in December 2019, it has spread worldwide. An outbreak in Japan occurred on a cruise ship, and this was followed by community-acquired COVID-19. Herein, we report three cases of COVID-19 that presented pneumonia following admission to Kitasato University Hospital. Patients were admitted based on the positive result of real-time reverse transcriptase–polymerase chain reaction (RT-PCR) tests for COVID-19 nucleic acid. All patients were diagnosed as suffering from non-severe COVID-19 pneumonia and were successfully treated with Lopinavir/Ritonavir (LPV/r). LPV/r could be an option for treating non-severe COVID-19 pneumonia in general and even in elderly patients.</text>
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          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="45954">
                <text>2020</text>
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            </elementTextContainer>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="45955">
                <text>covid-19, Elderly patient, lopinavir, cruise ship, Ritonavir, hyponatremia</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="45956">
                <text>10.3389/fmed.2020.00241</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="45957">
                <text>Epidemiology and Health</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="45958">
                <text>Korean Society of Epidemiology</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="45959">
                <text>Medicine (General)</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Prediction and Analysis of SARS-CoV-2-Targeting MicroRNA in Human Lung Epithelium</text>
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                <text>Jonathan  Tak-Sum Chow, Leonardo Salmena</text>
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                <text>Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), an RNA virus, is responsible for the coronavirus disease 2019 (COVID-19) pandemic of 2020. Experimental evidence suggests that microRNA can mediate an intracellular defence mechanism against some RNA viruses. The purpose of this study was to identify microRNA with predicted binding sites in the SARS-CoV-2 genome, compare these to their microRNA expression profiles in lung epithelial tissue and make inference towards possible roles for microRNA in mitigating coronavirus infection. We hypothesize that high expression of specific coronavirus-targeting microRNA in lung epithelia may protect against infection and viral propagation, conversely, low expression may confer susceptibility to infection. We have identified 128 human microRNA with potential to target the SARS-CoV-2 genome, most of which have very low expression in lung epithelia. Six of these 128 microRNA are differentially expressed upon in vitro infection of SARS-CoV-2. Additionally, 28 microRNA also target the SARS-CoV genome while 23 microRNA target the MERS-CoV genome. We also found that a number of microRNA are commonly identified in two other studies. Further research into identifying bona fide coronavirus targeting microRNA will be useful in understanding the importance of microRNA as a cellular defence mechanism against pathogenic coronavirus infections.</text>
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                <text>coronavirus, SARS-CoV-2, microRNA, lung epithelia, cellular antiviral defence</text>
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                <text>10.3390/genes11091002</text>
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                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Genetics</text>
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