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                <text>Sunny Chi Lik Au</text>
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                <text>Biotemas</text>
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                <text>Universidade Federal de Santa Catarina</text>
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                <text>The COVID-19 Cytokine Storm; What We Know So Far</text>
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                <text>Dina Ragab, Haitham Salah Eldin, Mohamed Taeimah, Rasha Khattab, Ramy Salem</text>
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                <text>COVID-19 is a rapidly spreading global threat that has been declared as a pandemic by the WHO. COVID-19 is transmitted via droplets or direct contact and infects the respiratory tract resulting in pneumonia in most of the cases and acute respiratory distress syndrome (ARDS) in about 15 % of the cases. Mortality in COVID-19 patients has been linked to the presence of the so-called “cytokine storm” induced by the virus. Excessive production of proinflammatory cytokines leads to ARDS aggravation and widespread tissue damage resulting in multi-organ failure and death. Targeting cytokines during the management of COVID-19 patients could improve survival rates and reduce mortality.</text>
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                <text>Immunologic diseases. Allergy</text>
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                <text>COVID-19 Lockdown Measures on Least Developing Economies in Africa-a case of Malawi Economy</text>
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                <text>George N. Chidimbah Munthali, Wu Xuelian</text>
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                <text>The outbreak of COVID-19 pandemic has caused the entire world at standstill affecting all the sectors of economies in the whole world. In order to reduce the spread of the cases and the mortality rate of this pandemics many economies have implemented a lot of social distancing measurers with the aim of separating people direct and indirect contacts as the Virus can be transferred through physical contact and is also an airborne, these isolations measures have proved to be effective in many countries. One of the most measures that the developed and developing economies are using is partial or full lockdown, despite being effective way of reducing the impact of the Virus, lockdown measures has also its own cost that the economies are to bier especially when it’s a total or full countrywide lockdown which policy makers must look into too. The approaches of lockdowns and attitudes of people towards lockdowns has been seen differencing in many countries depending on the political system of the government which is in that jurisdiction economic status of the country. This perspective recommends that Countries like Malawi and any other when implementing these lockdowns measures the authorities should consider the political system, costs and other the measures to carter for helping the people like proving stimulus package in order to have a successfully and effective lockdown which is highly recommended to be an effective way of combating the Virus.</text>
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                <text>the corresponding aurther is the second one</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Social sciences (General)</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>INTERVENÇÕES INFORMACIONAIS COMO APOIO ÀS FAMÍLIAS DE CRIANÇAS E ADOLESCENTES COM TRANSTORNO DO ESPECTRO AUTISTA (TEA) DURANTE PANDEMIA DA COVID-19:</text>
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                <text>Amanda Dourado Souza Akahosi Fernandes, Marina Speranza, Danieli Amanda Gasparini, Mayara Soler Ramos Mazak, Beatriz Bertasi Vitola, Thaís Thaler Souza</text>
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                <text>O objetivo deste estudo é relatar e refletir sobre as Intervenções Informacionais desenvolvidas em um projeto de extensão universitária que promove assistência às famílias de crianças e adolescentes com Transtorno do Espectro Autista (TEA), durante a pandemia da COVID-19. Para tanto, trata-se de um relato de experiência que se deu em três etapas: 1) acolhimento e levantamento das demandas das famílias, 2) elaboração de materiais informativos e 3) articulação com o território, divulgação e acesso aos materiais. Cartilhas, vídeo e infográfico foram produzidos e divulgados em diferentes mídias sociais e compartilhados em grupos online de familiares e profissionais.</text>
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                <text>2021</text>
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                <text>Terapia Ocupacional, Acesso à informação, Transtorno do espectro autista</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Visual arts</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Novel Coronavirus (SARS-CoV-2) Pandemic: Overview and Current Status</text>
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                <text>Serhat ÜNAL, Şehnaz ALP</text>
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                <text>In the end of December 2019, a novel coronavirus was identified as the cause of pneumonia cases in Wuhan, China. The disease was later named as COVID-19 (coronavirus disease 2019) and the causative agent was designated as SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). Even though the disease was suggested to be of zoonotic origin, human to human spread was also described and became the main mode of transmission. The number of cases significantly increased within a short period of time and the disease spread worldwide. On March 11, 2020, the World Health Organization announced COVID-19 outbreak as a pandemic. As of May 6, 2020, it has been reported that there are 3.588.773 people diagnosed with COVID-19 among 215 countries, territories or areas, and 247.503 people have died from the disease. In our country, the first case was identified on March 10, 2020, and the first death from the disease was reported on March 17, 2020. According to the data announced on May 6, 2020, the total number of cases detected in our country was 131.744, and the number of deaths related to the disease was 3584. The knowledge on the characteristics and epidemiology of SARS-CoV-2 and COVID-19 has been increasing day by day. Sequence analysis of the viral genome enabled the development of diagnostic tests and facilitated the initiation of research on both therapeutic options and vaccine development. In this review article, current information on the biology, epidemiology, clinical features, diagnosis, treatment, and prevention of SARS-CoV-2 and COVID-19 was discussed.</text>
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                <text>Martina Vispi, Teresa Corradin, Camilla Peccianti, Luca Feci, Laura Casini, Chiara Pisani, Susanna Fabbroni, Paola Corsetti, Margherita Croatto, Michele Pellegrino</text>
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                <text>On January 30, 2020, World Health Organization (WHO) stated that a new coronavirus disease outbreak [COronaVIrus Disease - 19 (COVID-19)] was an international public health emergency. Many news, often fake ones, about the derived pandemic rapidly spread along the media, thus leading many dermatological patients to identify as “risk category” and sometimes discontinue treatments by themselves. The Dermatology Units in Grosseto and Pordenone simultaneously carried out a data collection by remote-conducted visits, evaluating the incidence of COVID-19 in psoriatic patients. Only 1 patient (close contact of a case) as part of the psoriasis analyzed group was tested and turned out to be positive for SARS-CoV-2, developing no symptoms during the observation period. The collected information may suggest that psoriasis, biotechnologically treated or not, cannot promote or aggravate the clinical trend of the SARS-CoV-2 infection, hence stopping systemic therapy in negative or clinically free SARS-CoV-2 patients is not recommended in general.</text>
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                <text>Dermatology Reports</text>
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                <text>PAGEPress Publications</text>
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                <text>Dermatology</text>
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                <text>Guangzhao Yang, Zhihua Xu, Jian Wang, Xiandi Zhu, Guoqun Mao, Yuzhu Jia, Zongyu Xie, Jing Wang, Weiqun Ao</text>
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                <text>Abstract Background The novel coronavirus pneumonia (coronavirus disease 2019, COVID-19) has spread around the world. We aimed to recapitulate the clinical and CT imaging features of COVID-19 and their differences in three age groups. Methods The clinical and CT data of patients with COVID-19 (n = 307) that had been divided into three groups (Group 1:</text>
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                <text>10.1186/s12879-020-05154-9</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Infectious and parasitic diseases</text>
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                <text>Reprogramming of the Antibacterial Drug Vancomycin Results in Potent Antiviral Agents Devoid of Antibacterial Activity</text>
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                <text>Gyula Batta, Lieve Naesens, Anikó Borbás, Zsolt Szűcs, Annelies Stevaert, Eszter Ostorházi, Pál Herczegh</text>
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                <text>Influenza A and B viruses are a global threat to human health and increasing resistance to the existing antiviral drugs necessitates new concepts to expand the therapeutic options. Glycopeptide derivatives have emerged as a promising new class of antiviral agents. To avoid potential antibiotic resistance, these antiviral glycopeptides are preferably devoid of antibiotic activity. We prepared six vancomycin aglycone hexapeptide derivatives with the aim of obtaining compounds having anti-influenza virus but no antibacterial activity. Two of them exerted strong and selective inhibition of influenza A and B virus replication, while antibacterial activity was successfully eliminated by removing the critical N-terminal moiety. In addition, these two molecules offered protection against several other viruses, such as herpes simplex virus, yellow fever virus, Zika virus, and human coronavirus, classifying these glycopeptides as broad antiviral molecules with a favorable therapeutic index.</text>
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                <text>2020</text>
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                <text>antiviral, human coronavirus, Influenza Virus, glycopeptide antibiotic, vancomycin aglycone hexapeptide</text>
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                <text>10.3390/ph13070139</text>
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                <text>Epidemiology and Health</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>Korean Society of Epidemiology</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Medicine, Pharmacy and materia medica</text>
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