715 10 20655 https://www.socictopen.socict.org/files/original/ef88f77a5c444ce1421b7ad80b285277.pdf 5b8b97c901b393436c52a37e8d4e49ac Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Simulation-based evaluation of school reopening strategies during COVID-19: A case study of São Paulo, Brazil. Creator An entity primarily responsible for making the resource E H M Cruz, J M Maciel, C L Clozato, M S Serpa, P O A Navaux, E Meneses, M Abdalah, M Diener Description An account of the resource During the coronavirus disease 2019 (COVID-19) pandemic, many countries opted for strict public health measures, including closing schools. After some time, they have started relaxing some of those restrictions. To avoid overwhelming health systems, predictions for the number of new COVID-19 cases need to be considered when choosing a school reopening strategy. Using a computer simulation based on a stochastic compartmental model that includes a heterogeneous and dynamic network, we analyse different strategies to reopen schools in the São Paulo Metropolitan Area, including one similar to the official reopening plan. Our model allows us to describe different types of relations between people, each type with a different infectiousness. Based on our simulations and model assumptions, our results indicate that reopening schools with all students at once has a big impact on the number of new COVID-19 cases, which could cause a collapse of the health system. On the other hand, our results also show that a controlled school reopening could possibly avoid the collapse of the health system, depending on how people follow sanitary measures. We estimate that postponing the schools' return date for after a vaccine becomes available may save tens of thousands of lives just in the São Paulo Metropolitan Area compared to a controlled reopening considering a worst-case scenario. We also discuss our model constraints and the uncertainty of its parameters. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource epidemiology, coronavirus, covid-19, epidemics, Mathematical Modelling Identifier An unambiguous reference to the resource within a given context 10.1017/S0950268821001059 Source A related resource from which the described resource is derived Epidemiology and infection https://www.socictopen.socict.org/files/original/1a5d30369f2b0bfa27eb78a4f2b7a044.pdf 7e2fe99b4dbaea8882bb928cf62a2e1d Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Cross-Institutional Evaluation of the Abbott ARCHITECT SARS-CoV-2 IgG Immunoassay. Creator An entity primarily responsible for making the resource Joesph R Wiencek, Lorin M Bachmann, Kelly Dinwiddie, Greg W Miller, Lindsay A L Bazydlo Description An account of the resource To describe a cross-institutional approach to verify the Abbott ARCHITECT SARS-CoV-2 antibody assay and to document the kinetics of the serological response. We conducted analytical performance evaluation studies using the Abbott ARCHITECT SARS-CoV-2 antibody assay on 5 Abbott ARCHITECT i2000 automated analyzers at 2 academic medical centers. Within-run and between-run coefficients of variance (CVs) for the antibody assay did not exceed 5.6% and 8.6%, respectively, for each institution. Quantitative and qualitative results agreed for lithium heparin plasma, EDTA-plasma and serum specimen types. Results for all SARS-CoV-2 IgG-positive and -negative specimens were concordant among analyzers except for 1 specimen at 1 institution. Qualitative and quantitative agreement was observed for specimens exchanged between institutions. All patients had detectable antibodies by day 10 from symptom onset and maintained seropositivity throughout specimen procurement. The analytical performance characteristics of the Abbott ARCHITECT SARS-CoV-2 antibody assay within and between 2 academic medical center clinical laboratories were acceptable for widespread clinical-laboratory use. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource serology, covid-19, antibody, SARS-CoV-2, immuno-assay, EUA Identifier An unambiguous reference to the resource within a given context 10.1093/labmed/lmab011 Source A related resource from which the described resource is derived Laboratory medicine https://www.socictopen.socict.org/files/original/561313830e2ffde639ca1b403482acec.pdf fd5e02493af800f8ce4f423a11123ce3 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The Prevalence and Socio-Demographic Correlates of Food Insecurity in Poland Creator An entity primarily responsible for making the resource Joanna Myszkowska-Ryciak, Hanna Dudek Description An account of the resource While food insecurity (FI) has been extensively studied in many countries, there have been few empirical contributions in Poland to date. The main objective of our research was to identify the socio-demographic factors affecting the risk of FI in Poland within 2014–2019. Moreover, we aimed to examine the effects of the family-oriented social program “Family 500+” by comparing the situation in various types of households with children a few years before and after the program was launched. The analysis was based on the set of eight-item FI indicators adopted by the Food and Agriculture Organization using the Gallup World Poll nationally representative survey data. Based on our results the most vulnerable groups in the context of FI were identified. We confirmed the importance of education, gender, age, marital status, household composition, status of employment and income in preventing FI. The effectiveness of the support program in reducing FI was demonstrated as households with at least three children experienced significant improvement in the FI status during the studied years. These findings should be especially important in the context of the impact of the COVID-19 pandemic on FI. As FI can affect the quality and quantity of food choices it is associated with a poorer health status, which increases the risk of infection, including COVID-19, and worsens recovery prognosis. Planning an efficient response to the pandemic requires a comprehension of the increased risk of exposure experienced by people, especially those who are food insecure. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource food insecurity, households, Sociodemographic determinants, socioeconomic program Identifier An unambiguous reference to the resource within a given context 10.3390/ijerph17176221 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/9b2aff2e16bbcb9a3024fa812368b07e.pdf f0224bbd8ddd0eb278e10a171efef3e9 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Combating COVID 19 in a public sector hospital in Pakistan. Creator An entity primarily responsible for making the resource Mahmood Ayyaz, Kamran Khalid Chima, Usman Ismat Butt, Wasim Hayat Khan, Muhammad Umar, Muhammad Waris Farooka, Tayyiba Wasim Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, Pakistan, Response, tertiary care hospital, Our experience, Public hospital Identifier An unambiguous reference to the resource within a given context 10.1016/j.amsu.2020.10.041 Source A related resource from which the described resource is derived Annals of medicine and surgery (2012) https://www.socictopen.socict.org/files/original/1a2815cff233658736be6213a1d6233a.pdf 7b60cf5cb813d98490c6ed5deaa4936b Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Diagnosis and treatment delay of head and neck cancers during COVID-19 era in a tertiary care academic hospital: what should we expect? Creator An entity primarily responsible for making the resource Claudia Cassandro, Ettore Cassandro, Alfonso Scarpa, Pietro De Luca, Antonella Bisogno, Vito Colacurcio, Pasquale Marra, Angelo Camaioni Description An account of the resource Since the spreading of SARS-CoV-2 from China, all deferrable medical activities have been suspended, to redirect resources for the management of COVID patients. The goal of this retrospective study was to investigate the impact of COVID-19 on head and neck cancers' diagnosis in our Academic Hospital. A retrospective analysis of patients treated for head and neck cancers between March 12 and November 1, 2020 was carried out, and we compared these data with the diagnoses of the same periods of the 5 previous years. 47 patients were included in this study. We observed a significative reduction in comparison with the same period of the previous 5 years. Our findings suggest that the COVID-19 pandemic is associated with a decrease in the number of new H&N cancers diagnoses, and a substantial diagnostic delay can be attributable to COVID-19 control measures. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource covid-19, oncology, lockdown, Head and neck cancer, Diagnosis delay Identifier An unambiguous reference to the resource within a given context 10.1007/s00405-021-06834-1 Source A related resource from which the described resource is derived European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery https://www.socictopen.socict.org/files/original/79213b13d4e7b748c63ae85d26834806.pdf 92a0decaf26d63c6f98396224fe82795 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Neuro-telehealth for fragile patients in a tertiary referral neurological institute during the COVID-19 pandemic in Milan, Lombardy. Creator An entity primarily responsible for making the resource Davide Pareyson, Chiara Pantaleoni, Roberto Eleopra, Giuseppe De Filippis, Isabella Moroni, Elena Freri, Federica Zibordi, Sara Bulgheroni, Emanuela Pagliano, Daniela Sarti, Antonio Silvani, Licia Grazzi, Pietro Tiraboschi, Giuseppe Didato, Elena Anghileri, Anna Bersano, Laura Valentini, Sylvie Piacentini, Cristina Muscio, Matilde Leonardi, Caterina Mariotti, Marica Eoli, Sara Nuzzo, Fabrizio Tagliavini, Paolo Confalonieri, Francesca De Giorgi Description An account of the resource Lombardy was severely hit by the COVID-19 pandemic since February 2020 and the Health System underwent rapid reorganization. Outpatient clinics were stopped for non-urgent patients: it became a priority to manage hundreds of fragile neurological patients who suddenly had less reference points. In Italy, before the pandemic, Televisits were neither recognized nor priced. At the Fondazione IRCCS Istituto Neurologico C. Besta, we reorganized outpatient clinics to deliver Neuro-telemedicine services, including Televisits and Teleneurorehabilitation, since March 2020. A dedicated Working Group prepared the procedure, tested the system, and designed satisfaction questionnaires for adults and children. After a pilot phase, we prepared a procedure for Telemedicine outpatient clinics which was approved by hospital directions. It included prescription, booking, consenting, privacy and data protection, secure connection with patients (Teams Microsoft 365), electronic report preparation and delivery, reporting, and accountability of the services. During the March-September 2020 period, we delivered 3167 Telemedicine services, including 1618 Televisits, to 1694 patients (972 adults, 722 children) with a wide range of chronic neurological disorders. We successfully administered different clinical assessment and scales. Satisfaction among patients and caregivers was very high. During the dramatic emergency, we were able to take care of more than 1600 patients by organizing Neuro-telehealth in a few weeks, lessening the impact of the pandemic on fragile patients with chronic neurological disorders; this strategy is now stably embedded in our care pathways. In Italy, Telehealth is at present recognized and priced and is becoming a stable pillar of the health system. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource covid-19, telemedicine, neurology, Neuro-telehealth, Teleneurorehabilitation, Televisit Identifier An unambiguous reference to the resource within a given context 10.1007/s10072-021-05252-9 Source A related resource from which the described resource is derived Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology https://www.socictopen.socict.org/files/original/6b57f94874ba20f189151080a6dcb368.pdf b533cfaed65be4773651eab06b72a350 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A Review on Novel Drug Targets and Future Directions for COVID-19 Treatment Creator An entity primarily responsible for making the resource Wondmkun YT, Mohammed OA Description An account of the resource Yohannes Tsegyie Wondmkun,1 Ousman Ahmed Mohammed2 1Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia; 2College of Health Sciences, Woldia University, Woldia, EthiopiaCorrespondence: Yohannes Tsegyie WondmkunDepartment of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Churchill Avenue, P.O. Box 1176, Addis Ababa, EthiopiaEmail yohannes.tsegyie@aau.edu.etAbstract: Severe acute respiratory syndrome coronavirus-2 causes coronavirus disease-19 (COVID-19) that spreads quickly in the world. Considering the impact of this pandemic, researchers have been racing to understand the peculiar nature of the virus and the pathogenesis of the disease to uncover possible drug targets, effective therapeutic agents, and vaccines. Accordingly, numerous drug targets are identified by scientists. Among them, structural glycoproteins, virulence factors, host-specific receptors and enzymes, non-structure proteins, the Janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling pathway, and pro-inflammatory cytokines are discussed herein. This review summarizes the promising drug targets for COVID-19, and highlights antiviral strategies which depend on molecular interactions between viral small molecules and host biologic machinery for repurposing the available clinical drugs. In addition, it gives a strong rational basis for the ongoing discovery of new drugs and vaccines.Keywords: COVID-19, drug targets, SARS-COV-2, non-structural proteins, structural proteins Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, SARS-CoV-2, non-structural proteins, structural proteins, Drug targets Source A related resource from which the described resource is derived Biologics : Targets & Therapy Publisher An entity responsible for making the resource available Dove Medical Press Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine (General) https://www.socictopen.socict.org/files/original/148ccabaa2fdbb0c8558459a71fa12f2.pdf a97135739fde226a1b3d47c78dd8d100 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Germ-Free Mice Under Two-Layer Textiles Are Fully Protected From Bacteria in Sprayed Microdroplets: A Functional in vivo Test Method of Facemask/Filtration Materials Creator An entity primarily responsible for making the resource Alex Rodriguez-Palacios, Fabio Cominelli, Alex Rodriguez-Palacios, Alex Rodriguez-Palacios, Alex Rodriguez-Palacios, Mathew Conger, Mathew Conger, Fabio Cominelli, Fabio Cominelli Description An account of the resource Several studies have measured the effectiveness of masks at retaining particles of various sizes in vitro. To identify a functional in vivo model, herein we used germ-free (GF) mice to test the effectiveness of textiles as filtration material and droplet barriers to complement available in vitro-based knowledge. Herein, we report a study conducted in vivo with bacteria-carrying microdroplets to determine to what extent household textiles prevent contamination of GF mice in their environment. Using a recently validated spray-simulation method (mimicking a sneeze), herein we first determined that combed-cotton textiles used as two-layer-barriers covering the mouse cages prevented the contamination of all GF animals when sprayed 10–20 bacterial-droplet units/cm2. In additional to exposure trials, the model showed that GF mice were again protected by the combed-cotton textile after the acute exposure to 10 times more droplets (20 “spray-sneezes”, ~200 bacterial-droplet units/cm2). Overall, two-layer combed-cotton protected 100% of the GF mice from bacteria-carrying droplets (n = 20 exposure-events), which was significantly superior compared to 100% mouse contamination without textile coverage or when 95% partly covered (n = 18, Fisher-exact, p < 0.0001). Of relevance is that two different densities of cotton were equally effective (100%) in preventing contamination regardless of density (120–vs. 200 g/m2; T-test, p = 0.0028), suggesting that similar density materials could prevent droplet contamination. As a practical message, we conducted a speech trial (counting numbers, 1–100) with/without the protection of the same cotton textile used as face cover. The trial illustrated that contamination of surfaces occurs at a rate of >2–6 bacteria-carrying saliva-droplets per word (2.6 droplets/cm2, 30 cm) when speaking at 60–70 decibels and that cotton face covers fully prevent bacterial surface contamination. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, respiratory pandemic, cloth masks, fabrics, germ-free mouse model, public droplet safety Identifier An unambiguous reference to the resource within a given context 10.3389/fmed.2020.00504 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine (General) https://www.socictopen.socict.org/files/original/59f1fc6caef3f582e006377c0682159e.pdf d9101f09dc9be947d74371b0a30719d4 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource How will Covid-19 Influence Addictive Behaviours and their Management? Creator An entity primarily responsible for making the resource Pratima Murthy Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.1007/s40737-020-00207-3 Source A related resource from which the described resource is derived Journal of psychosocial rehabilitation and mental health https://www.socictopen.socict.org/files/original/c37ec9398af1e4f5ae21280db1a4bfaf.pdf 048221dedd9c894b358cf7250e129c25 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Low Visual Acuity Due to Acute Macular Neuroretinopathy Associated with COVID-19: A Case Report. Creator An entity primarily responsible for making the resource Mariana Nadais Aidar, Thaís Mota Gomes, Márgara Zanotele Hemerly de Almeida, Eric Pinheiro de Andrade, Pedro Durães Serracarbassa Description An account of the resource BACKGROUND Retinal sequelae have been reported in patients who have had COVID-19. This is a case report of acute macular neuroretinopathy (AMN), presenting with low visual acuity in the left eye, 14 days after the first symptoms of COVID-19 infection. CASE REPORT A 71-year-old woman presented for ophthalmological evaluation complaining of low visual acuity in the left eye, 14 days after the first symptoms of COVID-19 infection. COVID-19 was confirmed by a reverse-transcription polymerase chain reaction (RT-PCR) test. The left eye examination showed visual acuity of 0.5 logMAR, fundoscopy showed foveal pigment mobilization, fluorescein angiography revealed a hypofluorescent fovea surrounded by irregular hyperfluorescent defects, and spectral-domain optical coherence tomography showed central foveal thinning with disrupted interdigitation and ellipsoid zones. Given the clinical and imaging findings, the diagnosis of AMN was finalized. AMN usually resolves without specific treatment. CONCLUSIONS This case report shows that patients with COVID-19 can develop retinal involvement. AMN can be due to a viral infection, including COVID-19, and usually resolves without specific treatment. In the present case, there was no improvement in the patient's clinical condition in a 2-month follow-up to date. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Identifier An unambiguous reference to the resource within a given context 10.12659/AJCR.931169 Source A related resource from which the described resource is derived The American journal of case reports