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                <text>THE IMPLEMENTATION OF ONLINE-BASED LEARNING METHOD IN MADRASAH IBTIDAIYAH NEGERI 2 MATARAM</text>
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                <text>H.M Zaki</text>
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                <text>The massive and colossal migration from face-to-face learning method to the e-learning method due to the Covid-19 pandemic has become a new challenge for all educators in Mataram Islamic State Elementary School 2. The main challenge is to keep students stays active during the pandemic. This article use a qualitative approach with an explorative study, to reveals the problem of e-learning method. This learning method uses the Google Classroom, Zoom Cloud Meeting and WhatsApp Group as a variant of the learning application. In fact, this method has faced various problems; the parents faced some problems like a lack of funds, time and capability to help their children attending the online class. For students, e-learning is considered harder than face-to-face learning method. Meanwhile for the teacher, the problems were the lack of skills in using gadget and the difficulty of monitoring and controlling the activeness of students during online class.</text>
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                <text>Universitas Islam Negeri (UIN) Mataram</text>
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                <text>Safety Pathway Design for Patients Not Affected by COVID-19 During the SARS-CoV-2 Pandemic in an Italian University Hospital</text>
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                <text>Montella E, Caputi EM, Del Core M, Guida A, Triassi M</text>
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                <text>Emma Montella,1 Emanuele Mario Caputi,1 Mariapia Del Core,1 Antonella Guida,2 Maria Triassi1 1Public Health Department, &amp;ldquo;Federico II&amp;rdquo; University of Naples, Naples, Italy; 2Health Management, Local Health Authority (ASL) Caserta, Caserta, ItalyCorrespondence: Emma MontellaPublic Health Department, &amp;ldquo;Federico II&amp;rdquo; University of Naples, Via Sergio Pansini, 5, Naples 80131, ItalyTel +393332253185Email emma.montella@unina.it Cases of pneumonia of unknown etiology were identified in the city of Wuhan, the&amp;nbsp;most populated city in central China, late in December 2019. On January 7, 2020,&amp;nbsp;the virus responsible for this condition was defined as Coronavirus 2 Acute&amp;nbsp;Respiratory Syndrome (SARS-CoV-2); on February 11, the World Health&amp;nbsp;Organization announced that the respiratory disease caused by the new coronavirus&amp;nbsp;was called COVID-19. COVID-19 is a potentially fatal disease whose spread has&amp;nbsp;reached epidemiological criteria to be declared a pandemic, having infected,&amp;nbsp;according to WHO Coronavirus Disease Situation Reports, over 100,000&amp;nbsp; people&amp;nbsp;in more than 101 countries. This new public health emergency is challenging the&amp;nbsp;economy, the medical field and public health infrastructures. Health-care systems&amp;nbsp;worldwide have had to adapt their processes to face this new situation and attempt&amp;nbsp;to provide a global response, and countries that have already experienced the&amp;nbsp;emergency have a lot to teach. &amp;nbsp; &amp;nbsp;</text>
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                <text>Biotemas</text>
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                <text>Universidade Federal de Santa Catarina</text>
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                <text>Public aspects of medicine</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Yanqiu Wei, Gang Li, Juan Li, Jiaojiao Chu, Huihui Yue, Fengqin Zhang, Huilan Zhang</text>
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                <text>Mohamed Khateb, Noam Bosak, Maryam Muqary</text>
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                <text>SARS-CoV-2 is a highly pathogenic coronavirus that has caused an ongoing worldwide pandemic. Emerging in Wuhan, China in December 2019, the virus has spread rapidly around the world. Corona virus disease 2019 (COVID-19), which is caused by SARS-CoV-2, has resulted in significant morbidity and mortality. The most prominent symptoms of SARS-CoV-2 infection are respiratory. However, accumulating evidence highlights involvement of the central nervous system (CNS). This includes headache, anosmia, meningoencephalitis, acute ischemic stroke, and several presumably post/para-infectious syndromes and altered mental status not explained by respiratory etiologies. Interestingly, previous studies in animal models emphasized the neurotropism of coronaviruses; thus, these CNS manifestations of COVID-19 are not surprising. This minireview scans the literature regarding the involvement of the CNS in coronavirus infections in general, and in regard to the recent SARS-CoV-2, specifically.</text>
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                <text>Wossenseged Birhane Jemberie, Wossenseged Birhane Jemberie, Wossenseged Birhane Jemberie, Jennifer Stewart Williams, Jennifer Stewart Williams, Malin Eriksson, Ann-Sofie Grönlund, Nawi Ng, Nawi Ng, Marcus Blom Nilsson, Mojgan Padyab, Mojgan Padyab, Kelsey Caroline Priest, Mikael Sandlund, Fredrik Snellman, Dennis McCarty, Lena M. Lundgren, Lena M. Lundgren</text>
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                <text>COVID-19 shocked health and economic systems leaving millions of people without employment and safety nets. The pandemic disproportionately affects people with substance use disorders (SUDs) due to the collision between SUDs and COVID-19. Comorbidities and risk environments for SUDs are likely risk factors for COVID-19. The pandemic, in turn, diminishes resources that people with SUD need for their recovery and well-being. This article presents an interdisciplinary and international perspective on how COVID-19 and the related systemic shock impact on individuals with SUDs directly and indirectly. We highlight a need to understand SUDs as biopsychosocial disorders and use evidence-based policies to destigmatize SUDs. We recommend a suite of multi-sectorial actions and strategies to strengthen, modernize and complement addiction care systems which will become resilient and responsive to future systemic shocks similar to the COVID-19 pandemic.</text>
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                <text>10.3389/fpsyt.2020.00714</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Psychiatry</text>
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                <text>Modeling for Rapid Systems Prototyping: Hospital Situational Awareness System Design</text>
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                <text>Avi Shaked</text>
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                <text>The COVID-19 pandemic caught hospitals unprepared. The need to treat patients remotely and with limited resources led hospitals to identify a gap in their operational situational awareness. During the pandemic, Israeli Aerospace Industries helped hospitals to address the gap by designing a system to support their effective operation, management and decision making. In this paper, we report on the development of a functional, working prototype of the system using model-based engineering approach and tools. Our approach relies on domain-specific modeling, incorporating metamodeling and domain-specific representations based on the problem domain’s ontology. The tools practiced are those embedded into the Eclipse Modeling Framework—specifically, Ecore Tools and Sirius. While these technological tools are typically used to create dedicated, engineering-related modeling tools, in this work, we use them to create a functional system prototype. We discuss the advantages of our approach as well as the challenges with respect to the existing tools and their underlying technology. Based on the reported experience, we encourage practitioners to adopt model-based engineering as an effective way to develop systems. Furthermore, we call researchers and tool developers to improve the state-of-the-art as well as the existing implementations of pertinent tools to support model-based rapid prototyping.</text>
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                <text>2021</text>
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                <text>digital twin, model-based engineering, rapid prototype development, domain-specific models, Eclipse modeling</text>
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                <text>10.3390/systems9010012</text>
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                <text>Epidemiology and Health</text>
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                <text>Technology (General), Systems engineering</text>
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                <text>CLOUD-BASED INTEGRATION AND STANDARDIZATION OF ADDRESS DATA FOR DISASTER MANAGEMENT – A SOUTH AFRICAN CASE STUDY</text>
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                <text>G. Tredrea, S. Coetzee, V. Rautenbach</text>
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                <text>Addresses are essential for disaster risk management and response because they are used to locate people affected by a disaster or at risk of being affected. South Africa is vulnerable to disasters, however, despite a legislative framework for supporting disaster risk management that meets international standards, implementation falls short due to underfunding, poor interdepartmental coordination and lack of political support. The importance of cross jurisdictional address data was highlighted by the COVID-19 pandemic of 2020 when the geocoding of positive cases was hindered due to the lack of such address data in South Africa. In this paper, we present first results about a cloud-based tool for integrating address data from multiple municipalities into a single address dataset that conforms to the South African National Standard, SANS 1883-2:2017, Geographic information – Addresses: Part 2: Address data exchange. We reviewed and evaluated three cloud platforms for the prototype implementation. The integrated dataset is maintained in the cloud and therefore readily accessible by relevant organizations. At the same time, processing in the cloud can handle changing volumes of data with elasticity, i.e. computing power can be increased or decreased at short notice, as necessary during a disaster response. Furthermore, processing can be automated, thereby mitigating the risk of reduced manpower due to a disaster. Overall, a properly maintained cloud-based tool can result in more efficient use of resources presenting a viable and interesting alternative for underfunded disaster risk management centres in South Africa and other parts of the world.</text>
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                <text>10.5194/isprs-archives-XLIV-3-W1-2020-145-2020</text>
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                <text>The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences</text>
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                <text>Copernicus Publications</text>
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                <text>Engineering (General). Civil engineering (General), Technology, Applied optics. Photonics</text>
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                <text>Jerzy Sieńko,1 Maciej Kotowski,1 Anna Bogacz,2 Kacper Lechowicz,3 Sylwester Drożdżal,4 Jakub Rosik,5 Marek Sietnicki,6 Magdalena Sieńko,7 Katarzyna Kotfis3 1Department of General Surgery and Transplantology, Pomeranian Medical University in Szczecin, Szczecin, Poland; 2Department of Pharmacology and Phytochemistry, Institute of Natural Fibers and Medicinal Plants, Poznan, Poland; 3Department of Anaesthesiology, Intensive Therapy and Acute Intoxications, Pomeranian Medical University in Szczecin, Szczecin, Poland; 4Department of Pharmacokinetics and Monitored Therapy, Pomeranian Medical University in Szczecin, Szczecin, Poland; 5Department of Physiology, Pomeranian Medical University in Szczecin, Szczecin, Poland; 6Department of Civil Engineering and Architecture, West Pomeranian University of Technology in Szczecin, Szczecin, Poland; 7Department of Pediatrics, Endocrinology, Diabetology, Metabolic Diseases and Cardiology, Pomeranian Medical University in Szczecin, Szczecin, PolandCorrespondence: Katarzyna KotfisDepartment of Anaesthesiology, Intensive Therapy and Acute Intoxications, Pomeranian Medical University in Szczecin, Al. Powstańc&amp;oacute;w Wielkopolskich 72, Szczecin 70-111, PolandTel/ Fax +48 91 466 11 44Email katarzyna.kotfis@pum.edu.plAbstract: Since the beginning of 2020, the whole world has been struggling with the pandemic of Coronavirus Disease 2019 (COVID-19) caused by a novel coronavirus SARS-CoV-2. The SARS-CoV-2 infection depends on ACE2, TMPRSS2, and CD147, which are expressed on host cells. Several studies suggest that some single nucleotide polymorphisms (SNPs) of ACE2 might be a risk factor of COVID-19 infection. Genotypes affect ACE2 structure, its serum concentration, and levels of circulating angiotensin (1-7). Moreover, there is evidence that ACE genotype affects the outcomes of acute respiratory distress syndrome (ARDS) treatment, the most severe consequence of SARS-CoV-2 infection. COVID-19 morbidity, infection course, and mortality might depend on ACE D allele frequency. The aim of this narrative review was to analyze and identify the mechanisms of ACE-I and ARBs with particular emphasis on angiotensin receptors and their polymorphism in the light of COVID-19 pandemic as these medications are commonly prescribed to elderly patients. There is no direct evidence yet for ACE-I or ARBs in the treatment of COVID-19. However, for those already taking these medications, both the European Society of Cardiology and the American College of Cardiology recommend continuing the treatment, because at present, there is no clear clinical or scientific evidence to justify the discontinuation of ACE-I or ARBs. Individualized treatment decisions should be based on the clinical condition and co-morbidities of each patient.Keywords: SARI, hypertension, coronavirus, age, ACEI, ARB</text>
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                <text>coronavirus, Hypertension, sari, Age, ACEI, ARB</text>
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                <text>Biotemas</text>
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                <text>Universidade Federal de Santa Catarina</text>
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            <name>Title</name>
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                <text>Was the management of massive influx of critical COVID-19 patients adequate in the Paris area?</text>
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            <name>Creator</name>
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                <text>Michel Sfez, Stéphane Petit Maire, Etienne Fourquet</text>
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                <text>2021</text>
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                <text>covid-19, Paris area, influx management</text>
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            <name>Identifier</name>
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              <elementText elementTextId="65704">
                <text>10.1016/j.accpm.2020.10.015</text>
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                <text>Anaesthesia, critical care &amp; pain medicine</text>
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