819 10 20655 https://www.socictopen.socict.org/files/original/4f6d0701a6adc33e55a1063419353dd9.pdf 725d914f8a4fe7400b1c0b558121127d Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Does Copper Prevent Nosocomial Transmission of COVID-19? Creator An entity primarily responsible for making the resource Claire Coutureau, Madeline Pascard, Lukshe Kanagaratnam, Damien Jolly, Christophe de Champs Date A point or period of time associated with an event in the lifecycle of the resource 2021 Identifier An unambiguous reference to the resource within a given context 10.1016/j.jamda.2020.10.029 Source A related resource from which the described resource is derived Journal of the American Medical Directors Association https://www.socictopen.socict.org/files/original/210c3b53b10addfaef03b6a7095ab44f.pdf 75cd4e209bde9cbfe2c3aa1cca6d16f9 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Correction to: BCG revaccination of health workers in Brazil to improve innate immune responses against COVID-19: A structured summary of a study protocol for a randomised controlled trial. Creator An entity primarily responsible for making the resource Ana Paula Junqueira-Kipnis, Laura Raniere Borges Dos Anjos, Lília Cristina de Souza Barbosa, Adeliane Castro da Costa, Kellen Christina Malheiros Borges, Amanda da Rocha Oliveira Cardoso, Kaio Mota Ribeiro, Sarah Brena Aparecida Rosa, Carine de Castro Souza, Rogério Coutinho das Neves, Guylherme Saraiva, Sueli Meira da Silva, Erika Aparecida Silveira, Marcelo Fouad Rabahi, Marcus Barreto Conte, André Kipnis Description An account of the resource An amendment to this paper has been published and can be accessed via the original article. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.1186/s13063-020-04913-y Source A related resource from which the described resource is derived Trials https://www.socictopen.socict.org/files/original/6e323c4f2c426e13ef38303f933b8ced.pdf 0cfe11d5596e310bb9b243a77ed449e7 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Concurrent Antibiotic Therapy in Disseminated Strongyloidiasis. Creator An entity primarily responsible for making the resource Chia Siang Kow, Syed Shahzad Hasan Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.4269/ajtmh.20-1059a Source A related resource from which the described resource is derived The American journal of tropical medicine and hygiene https://www.socictopen.socict.org/files/original/57ac5fbb6991c0680d559d63fa96334f.pdf 64c59240390824a58f8ff7c0ebc9d64a Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Communicating Effectively About Emergency Use Authorization and Vaccines in the COVID-19 Pandemic. Creator An entity primarily responsible for making the resource Sandra Crouse Quinn, Amelia M Jamison, Vicki Freimuth Date A point or period of time associated with an event in the lifecycle of the resource 2021 Identifier An unambiguous reference to the resource within a given context 10.2105/AJPH.2020.306036 Source A related resource from which the described resource is derived American journal of public health https://www.socictopen.socict.org/files/original/ff129fe47c44cc0e1f16d03b9162e390.pdf 7aea973f2072d8ec23ef63a0f2b13069 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Serum potassium concentrations in COVID-19. Creator An entity primarily responsible for making the resource Dominika Szoke, Simone Caruso, Elena Aloisio, Sara Pasqualetti, Alberto Dolci, Mauro Panteghini Date A point or period of time associated with an event in the lifecycle of the resource 2021 Identifier An unambiguous reference to the resource within a given context 10.1016/j.cca.2020.11.012 Source A related resource from which the described resource is derived Clinica chimica acta; international journal of clinical chemistry https://www.socictopen.socict.org/files/original/610e95166dca66ce670ca0fb2aa99915.pdf 2951c3740e298e760d5f5b07443ffd00 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource COVID-19 impact on health care workers: Revisiting the metrics. Creator An entity primarily responsible for making the resource Haroon Rashid, Jatinder Katyal Date A point or period of time associated with an event in the lifecycle of the resource 2021 Identifier An unambiguous reference to the resource within a given context 10.1016/j.bbi.2020.11.026 Source A related resource from which the described resource is derived Brain, behavior, and immunity https://www.socictopen.socict.org/files/original/a27a238ea5b46c433106d544d11e443f.pdf c7fbf152a02dd3a5203f928ef8776721 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource N95 respirator reuse during the COVID-19 pandemic: Healthcare worker perceptions and attitudes. Creator An entity primarily responsible for making the resource Valeria Fabre, Sara E Cosgrove, Francis Catalfumo, Polly Trexler, Melanie Curless, Lisa L Maragakis, Clare Rock Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.1017/ice.2020.1348 Source A related resource from which the described resource is derived Infection control and hospital epidemiology https://www.socictopen.socict.org/files/original/762d707aa298521ba1a6225fd17f67de.pdf 46298f376b68159ae42a54aafd89916e Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Hypothesis: Alpha-1-antitrypsin is a promising treatment option for COVID-19. Creator An entity primarily responsible for making the resource Xiyuan Bai, Joseph Hippensteel, Alida Leavitt, James P Maloney, David Beckham, Cindy Garcia, Qing Li, Brian M Freed, Diane Ordway, Robert A Sandhaus, Edward D Chan Description An account of the resource No definitive treatment for COVID-19 exists although promising results have been reported with remdesivir and glucocorticoids. Short of a truly effective preventive or curative vaccine against SARS-CoV-2, it is becoming increasingly clear that multiple pathophysiologic processes seen with COVID-19 as well as SARS-CoV-2 itself should be targeted. Because alpha-1-antitrypsin (AAT) embraces a panoply of biologic activities that may antagonize several pathophysiologic mechanisms induced by SARS-CoV-2, we hypothesize that this naturally occurring molecule is a promising agent to ameliorate COVID-19. We posit at least seven different mechanisms by which AAT may alleviate COVID-19. First, AAT is a serine protease inhibitor (SERPIN) shown to inhibit TMPRSS-2, the host serine protease that cleaves the spike protein of SARS-CoV-2, a necessary preparatory step for the virus to bind its cell surface receptor ACE2 to gain intracellular entry. Second, AAT has anti-viral activity against other RNA viruses HIV and influenza as well as induces autophagy, a known host effector mechanism against MERS-CoV, a related coronavirus that causes the Middle East Respiratory Syndrome. Third, AAT has potent anti-inflammatory properties, in part through inhibiting both nuclear factor-kappa B (NFκB) activation and ADAM17 (also known as tumor necrosis factor-alpha converting enzyme), and thus may dampen the hyper-inflammatory response of COVID-19. Fourth, AAT inhibits neutrophil elastase, a serine protease that helps recruit potentially injurious neutrophils and implicated in acute lung injury. AAT inhibition of ADAM17 also prevents shedding of ACE2 and hence may preserve ACE2 inhibition of bradykinin, reducing the ability of bradykinin to cause a capillary leak in COVID-19. Fifth, AAT inhibits thrombin, and venous thromboembolism and in situ microthrombi and macrothrombi are increasingly implicated in COVID-19. Sixth, AAT inhibition of elastase can antagonize the formation of neutrophil extracellular traps (NETs), a complex extracellular structure comprised of neutrophil-derived DNA, histones, and proteases, and implicated in the immunothrombosis of COVID-19; indeed, AAT has been shown to change the shape and adherence of non-COVID-19-related NETs. Seventh, AAT inhibition of endothelial cell apoptosis may limit the endothelial injury linked to severe COVID-19-associated acute lung injury, multi-organ dysfunction, and pre-eclampsia-like syndrome seen in gravid women. Furthermore, because both NETs formation and the presence of anti-phospholipid antibodies are increased in both COVID-19 and non-COVID pre-eclampsia, it suggests a similar vascular pathogenesis in both disorders. As a final point, AAT has an excellent safety profile when administered to patients with AAT deficiency and is dosed intravenously once weekly but also comes in an inhaled preparation. Thus, AAT is an appealing drug candidate to treat COVID-19 and should be studied. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource SARS-CoV-2, Nets, serine protease, anti-inflammation, serpin, Anti-thrombosis Identifier An unambiguous reference to the resource within a given context 10.1016/j.mehy.2020.110394 Source A related resource from which the described resource is derived Medical hypotheses https://www.socictopen.socict.org/files/original/9034f4a2cd8fdb119c4f40c84e36c0d5.pdf e406c9060f2affe27ec176b2fa2a2f1b Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Letter to the editor: Coronavirus disease 2019 (COVID-19) markedly increased mortality in patients with hip fracture: A systematic review and meta-analysis. Creator An entity primarily responsible for making the resource Nicholas D Clement Date A point or period of time associated with an event in the lifecycle of the resource 2021 Identifier An unambiguous reference to the resource within a given context 10.1016/j.jcot.2020.11.007 Source A related resource from which the described resource is derived Journal of clinical orthopaedics and trauma https://www.socictopen.socict.org/files/original/0b55e7e957acfa9bd4138e191d9ae6ab.pdf 622e14b6fb34dd0608b372d0f6f4a1ce Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Author reply - Letter to the editor The challenges of quantifying the psychological burden of COVID-19 on heathcare workers"." Creator An entity primarily responsible for making the resource Sofia Pappa, Vassilis G Giannakoulis, Eleni Papoutsi, Paraskevi Katsaounou Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource Healthcare workers, Anxiety, covid-19, Depression, insomnia Identifier An unambiguous reference to the resource within a given context 10.1016/j.bbi.2020.11.025 Source A related resource from which the described resource is derived Brain, behavior, and immunity