825 10 20655 https://www.socictopen.socict.org/files/original/06f6eda98329ffcaa582f03f2b637c55.pdf ac498cb8526d66ec76550c19b9be87e9 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Mortality reduction in 46 severe Covid-19 patients treated with hyperimmune plasma. A proof of concept single arm multicenter trial. Creator An entity primarily responsible for making the resource Cesare Perotti, Fausto Baldanti, Raffaele Bruno, Claudia Del Fante, Elena Seminari, Salvatore Casari, Elena Percivalle, Claudia Glingani, Valeria Musella, Mirko Belliato, Martina Garuti, Federica Meloni, Marilena Frigato, Antonio Di Sabatino, Catherine Klersy, Giuseppe De Donno, Massimo Franchini, Covid-Plasma Task Force Description An account of the resource Hyperimmune plasma from Covid-19 convalescent is a potential treatment for severe Covid-19. We conducted a multicenter one arm proof of concept interventional study. Patients with Covid-19 disease with moderate-to-severe Acute Respiratory Distress Syndrome, elevated C-reactive Protein and need for mechanical ventilation and/or CPAP were enrolled. One to three 250-300 ml unit of hyperimmune plasma (neutralizing antibodies titer ≥1:160) were administered. Primary outcome was 7-days hospital mortality. Secondary outcomes were PaO2/FiO2, laboratory and radiologic changes, as well as weaning from mechanical ventilation and safety. The study observed 46 patients from March, 25 to April, 21 2020. Patients were aged 63, 61% male, of them, 30 were on CPAP and 7 intubated. PaO2/FiO2 was 128 (SD 47). Bilateral infiltrates on chest X-ray was present in 36 patients (84%). Symptoms and ARDS duration were 14 (SD 7) and 6 days (SD 3). Three patients (6.5%) died within 7 days as compared to an expected 15% from the National Statistics and 30% from a small concurrent cohort of 23 patients. The upper one-sided 90%CI was 13.9%, allowing to reject the null hypothesis of a 15% mortality. PaO2/FiO2 increased by 112 units (95%CI 82 to142) in survivors, the chest radiogram severity decreased in 23% (95%CI 5% to 42%); CRP, Ferritin and LDH decreased by 60, 36 and 20% respectively. Weaning from CPAP was obtained in 26/30 patients and 3/7 were extubated. Five serious adverse events occurred in 4 patients (2 likely, 2 possible treatment related). In conclusion, Hyperimmune plasma in Covid-19 shows promising benefits, to be confirmed in a randomized controlled trial. This proof of concept study could open to future developments including hyperimmune plasma banking, development of standardized pharmaceutical products and monoclonal antibodies. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.3324/haematol.2020.261784 Source A related resource from which the described resource is derived Haematologica https://www.socictopen.socict.org/files/original/d57964bc1d53b63ad1ff47b89eec27ee.pdf f816f36e7b5e75e5340b9718fae58a5b Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource ABO blood groups are not associated with risk of acquiring the SARS-CoV-2 infection in young adults. Creator An entity primarily responsible for making the resource Laurys Boudin, Frédéric Janvier, Olivier Bylicki, Fabien Dutasta Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.3324/haematol.2020.265066 Source A related resource from which the described resource is derived Haematologica https://www.socictopen.socict.org/files/original/7dc73b2142d14f9fac848cb522da3191.pdf 1bde9e3517c79b0eb698d44ad28824d3 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Perforin gene variant A91V in young patients with severe COVID-19. Creator An entity primarily responsible for making the resource Oscar Cabrera-Marante, Edgard Rodríguez de Frías, Daniel E Pleguezuelo, Luis M Allende, Antonio Serrano, Rocío Laguna-Goya, María Esther Mancebo, Paloma Talayero, Luis Álvarez-Vallina, Pablo Morales, Maria José Castro-Panete, Estela Paz-Artal Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.3324/haematol.2020.260307 Source A related resource from which the described resource is derived Haematologica https://www.socictopen.socict.org/files/original/91713171aabf4768f067a0b700d81d43.pdf 04e22f4e30541f303b98974b95656052 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Complement C5 inhibition in patients with COVID-19 - a promising target? Creator An entity primarily responsible for making the resource Regis Peffault de Latour, Anne Bergeron, Etienne Lengline, Thibault Dupont, Armance Marchal, Lionel Galicier, Nathalie de Castro, Louise Bondeelle, Michael Darmon, Clairelyne Dupin, Guillaume Dumas, Pierre Leguen, Isabelle Madelaine, Sylvie Chevret, Jean-Michel Molina, Elie Azoulay, Veronique Fremeaux-Bacchi, Core Group Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.3324/haematol.2020.260117 Source A related resource from which the described resource is derived Haematologica https://www.socictopen.socict.org/files/original/1facb693bdc661b1c25f0c8004bfd598.pdf 0fcd74af061a51bce8f528b677e2690d Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource COVID-19: risk of infection is high, independently of ABO blood group. Creator An entity primarily responsible for making the resource Willy Albert Flegel Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.3324/haematol.2020.266593 Source A related resource from which the described resource is derived Haematologica https://www.socictopen.socict.org/files/original/6f51561766d1fe6f6d0e65da47d873a5.pdf 58564f74a055f24156fb4ea2dac3bda8 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Serological diagnosis of SARS-CoV-2. Diagnostic rentability of a chemiluminescence test. Creator An entity primarily responsible for making the resource Ana Infante Urrios, Laura Navarro Pérez, Fernando Buñuel Adán, Victoria Ortiz de la Tabla Ducasse Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.1016/j.eimc.2020.10.006 Source A related resource from which the described resource is derived Enfermedades infecciosas y microbiologia clinica (English ed.) https://www.socictopen.socict.org/files/original/6a4ae9f1cfac233346d7a489805db29f.pdf 5f07fd883c5a705fd38862cb460cf6d9 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Incentivising wealthy nations to participate in the COVID-19 Vaccine Global Access Facility (COVAX): a game theory perspective Creator An entity primarily responsible for making the resource Gavin Yamey, Matthew Johnson, Osondu Ogbuoji, Kaci Kennedy McDade, David McAdams, Siddharth Dixit Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.1136/bmjgh-2020-003627 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine (General) https://www.socictopen.socict.org/files/original/a08b5904b3b09d0d0f89554cc122177b.pdf ed29263829da9c48449dc65cfd44d837 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Development of a multi-antigenic SARS-CoV-2 vaccine candidate using a synthetic poxvirus platform Creator An entity primarily responsible for making the resource Flavia Chiuppesi, Marcela d’Alincourt Salazar, Heidi Contreras, Vu H. Nguyen, Joy Martinez, Yoonsuh Park, Jenny Nguyen, Mindy Kha, Angelina Iniguez, Qiao Zhou, Teodora Kaltcheva, Roman Levytskyy, Nancy D. Ebelt, Tae Hyuk Kang, Xiwei Wu, Thomas F. Rogers, Edwin R. Manuel, Yuriy Shostak, Don J. Diamond, Felix Wussow Description An account of the resource Chiuppesi et al. demonstrate the use of a synthetic poxvirus-based platform to rapidly generate multi-antigenic vaccine candidates expressing spike and nucleocapsid antigens of SARS-CoV-2. Immunization of mice stimulates potent antigen-specific humoral and cellular immune responses, including neutralizing antibodies. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.1038/s41467-020-19819-1 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Science https://www.socictopen.socict.org/files/original/74e32afdf53b5e38a6280e6df3dc5925.pdf 734f1cceb3623a9e94431784a3a37c65 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Modelling intestinal inflammation and infection using 'mini-gut' organoids. Creator An entity primarily responsible for making the resource Vivian S W Li Date A point or period of time associated with an event in the lifecycle of the resource 2021 Identifier An unambiguous reference to the resource within a given context 10.1038/s41575-020-00391-4 Source A related resource from which the described resource is derived Nature reviews. Gastroenterology & hepatology https://www.socictopen.socict.org/files/original/efd47229211d104b16c7d0d05bbcd539.pdf d9b0455cee20171e0edfa0d739bcc789 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Detection of SARS-CoV-2 in placental but not fetal tissues in the second trimester. Creator An entity primarily responsible for making the resource Jacob E Valk, Alexander M Chong, Anne-Catrin Uhlemann, Larisa Debelenko Date A point or period of time associated with an event in the lifecycle of the resource 2021 Identifier An unambiguous reference to the resource within a given context 10.1038/s41372-020-00877-8 Source A related resource from which the described resource is derived Journal of perinatology : official journal of the California Perinatal Association