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SARS coronavirus nsp1 protein induces template-dependent endonucleolytic cleavage of mRNAs: viral mRNAs are resistant to nsp1-induced RNA cleavage.
SARS coronavirus (SCoV) nonstructural protein (nsp) 1, a potent inhibitor of host gene expression, possesses a unique mode of action: it binds to 40S ribosomes to inactivate their translation functions and induces host mRNA degradation. Our previous…
Position: 5505 (38 views)
Analysis of the Risk Factors for Nosocomial Bacterial Infection in Patients with COVID-19 in a Tertiary Hospital
Keping Cheng,1 Miao He,2 Qin Shu,3 Ming Wu,3 Cuifang Chen,2 Yulei Xue4 1Department of Infection Management, Zhongda Hospital Affiliated to Southeast University, Nanjing 210009, People’s Republic of China; 2Department of Public Health, Huangshi…
Position: 18750 (18 views)
Decreased Anthropogenic CO<sub>2</sub> Emissions during the COVID-19 Pandemic Estimated from FTS and MAX-DOAS Measurements at Urban Beijing
The COVID-19 pandemic has led to ongoing reductions in economic activity and anthropogenic emissions. Beijing was particular badly affected by lockdown measures during the early months of the COVID-19 pandemic. It has significantly reduced the CO2…
Position: 7042 (34 views)
Sequential introduction of single room isolation and hand hygiene campaign in the control of methicillin-resistant <it>Staphylococcus aureus </it>in intensive care unit
Abstract Background After renovation of the adult intensive care unit (ICU) with installation of ten single rooms, an enhanced infection control program was conducted to control the spread of methicillin-resistant Staphylococcus aureus (MRSA) in our…
Position: 8102 (32 views)
Sequential introduction of single room isolation and hand hygiene campaign in the control of methicillin-resistant <it>Staphylococcus aureus </it>in intensive care unit
Abstract Background After renovation of the adult intensive care unit (ICU) with installation of ten single rooms, an enhanced infection control program was conducted to control the spread of methicillin-resistant Staphylococcus aureus (MRSA) in our…
Position: 9320 (30 views)
Investment Opportunity in Online Survey Industry under COVID-19
The COVID-19 outbreak left the world an island shrouded in repression, causing great losses to the world economy and blowing numerous investors in the financial market. However, at the same time, emerging online industries also bring them new…
Position: 12396 (26 views)
Nucleic Acid Sandwich Hybridization Assay with Quantum Dot-Induced Fluorescence Resonance Energy Transfer for Pathogen Detection
This paper reports a nucleic acid sandwich hybridization assay with a quantum dot (QD)-induced fluorescence resonance energy transfer (FRET) reporter system. Two label-free hemagglutinin H5 sequences (60-mer DNA and 630-nt cDNA fragment) of avian…
Position: 11571 (27 views)
A Systematic Review and Meta-Analysis of Cancer Patients Affected by a Novel Coronavirus.
Cancer patients with coronavirus disease 2019 (COVID-19) have been reported to have double the case fatality rate of the general population. A systematic search of PubMed, Embase, and Cochrane Central was done for studies on cancer patients with…
Position: 17478 (20 views)
Targeting Coronaviral Replication and Cellular JAK2 Mediated Dominant NF-κB Activation for Comprehensive and Ultimate Inhibition of Coronaviral Activity
Abstract Tylophorine-based compounds exert broad spectral, potent inhibition of coronaviruses. NF-κB activation is a common pro-inflammatory response of host cells to viral infection. The aims of this study were to (i) find an effective combination…
Position: 18172 (19 views)
Media Exposure Related to the PTSS During COVID-19 Pandemic: The Mediating Role of Risk Perception
Objectives: The objectives of this study are to assess the relationship between media exposure and post-traumatic stress symptoms (PTSS) and to highlight the underlying mechanisms mediated by risk perception.Methods: This survey was conducted online…
Position: 4136 (43 views)