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Novel rapid identification of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) by real-time RT-PCR using BD Max Open System in Taiwan
Coronavirus disease 2019 has become a worldwide pandemic. By April 7, 2020, approximately 1,279,722 confirmed cases were reported worldwide including those in Asia, European Region, African Region and Region of the Americas. Rapid and accurate…
Position: 16739 (21 views)
Serological Approaches for COVID-19: Epidemiologic Perspective on Surveillance and Control
Since December 2019, the novel coronavirus, SARS-CoV-2, has garnered global attention due to its rapid transmission, which has infected more than two million people worldwide. Early detection of SARS-CoV-2 is one of the crucial interventions to…
Position: 16739 (21 views)
Modeling the Spread of Epidemics Based on Cellular Automata
Mathematical modeling is a powerful tool to study the process of the spread of infectious diseases. Among various mathematical methods for describing the spread of infectious diseases, the cellular automaton makes it possible to explicitly simulate…
Position: 10061 (29 views)
The Mechanism and Clinical Outcome of patients with Corona Virus Disease 2019 Whose Nucleic Acid Test has changed from negative to positive, and the therapeutic efficacy of Favipiravir: A structured summary of a study protocol for a randomised controlled trial
Abstract Objectives A variety of possible mechanisms can make the nucleic acid test of patients who meet the discharge conditions positive again, including reinfection, reactivation of the original virus, lack of strict discharge criteria, new…
Position: 16739 (21 views)
Profiling of substrate specificities of 3C-like proteases from group 1, 2a, 2b, and 3 coronaviruses.
BACKGROUND: Coronaviruses (CoVs) can be classified into alphacoronavirus (group 1), betacoronavirus (group 2), and gammacoronavirus (group 3) based on diversity of the protein sequences. Their 3C-like protease (3CL(pro)), which catalyzes the…
Position: 5182 (39 views)
Profiling of substrate specificity of SARS-CoV 3CL.
BACKGROUND: The 3C-like protease (3CL(pro)) of severe acute respiratory syndrome-coronavirus is required for autoprocessing of the polyprotein, and is a potential target for treating coronaviral infection. METHODOLOGY/PRINCIPAL FINDINGS: To obtain a…
Position: 1901 (58 views)
Concurrent Antibiotic Therapy in Disseminated Strongyloidiasis.
Position: 12398 (26 views)
COVID-19 Severity and Neonatal BCG Vaccination among Young Population in Taiwan
Background: Data have not been reported to explore the relation between COVID-19 severity and BCG vaccination status at the individual patient level. Methods: Taiwan has a nationwide neonatal BCG vaccination program that was launched in 1965. The…
Position: 20307 (14 views)
Inhibition of SARS-CoV 3C-like Protease Activity by Theaflavin-3,3'-digallate (TF3)
SARS-CoV is the causative agent of severe acute respiratory syndrome (SARS). The virally encoded 3C-like protease (3CLPro) has been presumed critical for the viral replication of SARS-CoV in infected host cells. In this study, we screened a natural…
Position: 6598 (35 views)
Outsourcing Reverse Logistics for E-Commerce Retailers: A Two-Stage Fuzzy Optimization Approach
On the heels of the online shopping boom during the Covid-19 pandemic, the electronic commerce (e-commerce) surge has many businesses facing an influx in product returns. Thus, relevant companies must implement robust reverse logistics strategies to…
Position: 10061 (29 views)