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Lung epithelial cells have virus-specific and shared gene expression responses to infection by diverse respiratory viruses.
The severity of respiratory viral infections is partially determined by the cellular response mounted by infected lung epithelial cells. Disease prevention and treatment is dependent on our understanding of the shared and unique responses elicited by…
Position: 7404 (40 views)
The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases.
Infection by enveloped coronaviruses (CoVs) initiates with viral spike (S) proteins binding to cellular receptors, and is followed by proteolytic cleavage of receptor-bound S proteins, which prompts S protein-mediated virus-cell membrane fusion.…
Position: 11109 (34 views)
Cynomolgus macaque as an animal model for severe acute respiratory syndrome.
The emergence of severe acute respiratory syndrome (SARS) in 2002 and 2003 affected global health and caused major economic disruption. Adequate animal models are required to study the underlying pathogenesis of SARS-associated coronavirus (SARS-CoV)…
Position: 2440 (61 views)
Ecological Resilience of Food Systems in Response to the COVID-19 Crisis
Resilience of food systems is being tested by the COVID-19 disruption. As with any severe disruption, collapse of some systems, innovation in others, and total reorganization of some will occur. Direct delivery of food, online farmers markets,…
Position: 12628 (32 views)
Pediatric Subspecialty Adoption of Telemedicine Amidst the COVID-19 Pandemic: An Early Descriptive Analysis
Telemedicine has rapidly expanded in many aspects of pediatric care as a result of the COVID-19 pandemic. However, little is known about what factors may make pediatric subspeciality care more apt to long-term adoption of telemedicine. To better…
Position: 5804 (44 views)
The New Covid-19" Home Office Worker: Evolving Computer-Human Interactions and the Perceived Value of Workplace Technology"
The context for this paper is the ongoing Covid-19 Global Pandemic and the guidance from the majority of nation-state governments for all central office based type workers to completely shift to working from home, advice which business and…
Position: 20562 (17 views)
Type 2 and interferon inflammation regulate SARS-CoV-2 entry factor expression in the airway epithelium
ACE2 and TMPRSS2 have received recent attention as entry factors for SARS-CoV-2. Here the authors analyze nasal airway transcriptome data from 695 children determining ACE2 and TMPRSS2 expression is induced by viral and type2 inflammation,…
Position: 12628 (32 views)
COVID-19 Patients With CNS Complications and Neuropathologic Features of Acute Disseminated Encephalomyelitis and Acute Hemorrhagic Leukoencephalopathy.
Position: 14962 (29 views)
Response Regarding: How to Manage Head Injury With COVID-19 Pneumonitis on Mars? Rare but High Impact Complex Medical Emergencies in Space"."
Position: 18558 (24 views)
Dosis y frecuencia de biofertilizantes en Cucumis sativus L. Municipio de Siuna RACCN Nicaragua
La aplicación de abonos orgánicos en la producción agrícola, ha constituido especial importancia desde la percepción de calidad, inocuidad y medio ambiente, en el municipio de Siuna, ya que se han realizado estudios sobre el efecto de los abonos…
Position: 11859 (33 views)