24 10 20655 https://www.socictopen.socict.org/files/original/b1fe3d5b96a12d22d4c20e27fb4a184c.pdf ce5d3e2102786d8341ce5cd74775a99b Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Attenuation of mouse hepatitis virus by deletion of the LLRKxGxKG region of Nsp1. Creator An entity primarily responsible for making the resource Lin Lei, SUN Ying, Luo Baojun, Yang Yi, He Xiang, Su-Wen Li, Sun Zounan, Guo Deyin, Zhuqing Yu, Liu Jingmei, Chang Guohui Description An account of the resource Coronaviruses are a family of large positive-sense RNA viruses that are responsible for a wide range of important veterinary and human diseases. Nsp1 has been shown to have an important role in the pathogenetic mechanisms of coronaviruses in vivo. To assess the function of a relatively conserved domain (LLRKxGxKG) of MHV nsp1, a mutant virus, MHV-nsp1-27D, with a 27 nts (LLRKxGxKG) deletion in nsp1, was constructed using a reverse genetic system with a vaccinia virus vector. The mutant virus had similar growth kinetics to MHV-A59 wild-type virus in 17CI-1 cells, but was highly attenuated in vivo. Moreover, the mutant virus completely protected C57BL/6 mice from a lethal MHV-A59 challenge. To further analyze the mechanism of the attenuation of the mutant virus, changes in reporter gene expression were measured in nsp1- or nsp1-27D-expressing cells; the results showed that nsp1 inhibited reporter gene expression controlled by different promoters, but that this inhibition was reduced for nsp1-27D. The research in vivo and in vitro suggests that the LLRKxGxKG region of nsp1 may play an important role in this process. Date A point or period of time associated with an event in the lifecycle of the resource 2013 Identifier An unambiguous reference to the resource within a given context DOI: 10.1371/journal.pone.0061166 Source A related resource from which the described resource is derived PLoS ONE Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Science, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/c11734e455d7c7644edfac985cdbfe11.pdf cd2942e92a4edd8c635d0dd656133f27 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Estrogens induce expression of membrane-associated estrogen receptor α isoforms in lactotropes. Creator An entity primarily responsible for making the resource Sandra Zárate, Gabriela Jaita, Jimena Ferraris, Guadalupe Eijo, María L Magri, Daniel Pisera, Adriana Seilicovich Description An account of the resource Estrogens are key to anterior pituitary function, stimulating hormone release and controlling cell fate to achieve pituitary dynamic adaptation to changing physiological conditions. In addition to their classical mechanism of action through intracellular estrogen receptors (ERs), estrogens exert rapid actions via cell membrane-localized ERs (mERs). We previously showed that E2 exerts a rapid pro-apoptotic action in anterior pituitary cells, especially in lactotropes and somatotropes, through activation of mERs. In the present study, we examined the involvement of mERα in the rapid pro-apoptotic action of estradiol by TUNEL in primary cultures of anterior pituitary cells from ovariectomized rats using a cell-impermeable E2 conjugate (E2-BSA) and an ERα selective antagonist (MPP dihydrochloride). We studied mERα expression during the estrous cycle and its regulation by gonadal steroids in vivo by flow cytometry. We identified ERα variants in the plasma membrane of anterior pituitary cells during the estrous cycle and studied E2 regulation of these mERα variants in vitro by surface biotinylation and Western Blot. E2-BSA-induced apoptosis was abrogated by MPP in total anterior pituitary cells and lactotropes. In cycling rats, we detected a higher number of lactotropes and a lower number of somatotropes expressing mERα at proestrus than at diestrus. Acute E2 treatment increased the percentage of mERα-expressing lactotropes whereas it decreased the percentage of mERα-expressing somatotropes. We detected three mERα isoforms of 66, 39 and 22 kDa. Expression of mERα66 and mERα39 was higher at proestrus than at diestrus, and short-term E2 incubation increased expression of these two mERα variants. Our results indicate that the rapid apoptotic action exerted by E2 in lactotropes depends on mERα, probably full-length ERα and/or a 39 kDa ERα variant. Expression and activation of mERα variants in lactotropes could be one of the mechanisms through which E2 participates in anterior pituitary cell renewal during the estrous cycle. Date A point or period of time associated with an event in the lifecycle of the resource 2012 Identifier An unambiguous reference to the resource within a given context DOI: 10.1371/journal.pone.0041299 Source A related resource from which the described resource is derived PLoS ONE Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Science, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/9a143558408b887e1af926f32064f75a.pdf 68b0900314cf2d6dbdc556b115f7bfae Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New coronavirus pneumonia COVID-19 and ocular surface transmission Creator An entity primarily responsible for making the resource Ming-Zhi Zhang Description An account of the resource Since the end of 2019, the novel coronavirus pneumonia(COVID-19)has rapidly spread in Wuhan City, Hubei Province of China. This has aroused great concern of the Chinese government and the international community. There have been unconfirmed threads of COVID-19 patients with conjunctivitis as the first symptom. Therefore, the issue that whether and how the novel coronavirus strain SARS-CoV-2 infection is transmitted through the ocular surface has become a new concern. In the absence of clinical and experimental evidence of COVID-19 in ocular infection, we have conducted a retrospective literature analysis of viral pathogens that simultaneously trigger ocular lesions during the onset of epidemic diseases. The purpose of this paper is to provide some reference and suggestions for appropriately understanding of ocular protection in the prevention and control of the COVID-19. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource infection; sars-cov-2; pneumonia; ocular surface; transmission mode, infection, SARS-CoV-2, Pneumonia, ocular surface, transmission mode Identifier An unambiguous reference to the resource within a given context DOI: 10.3980/j.issn.1672-5123.2020.3.01 Source A related resource from which the described resource is derived Guoji Yanke Zazhi Publisher An entity responsible for making the resource available Press of International Journal of Ophthalmology (IJO PRESS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Ophthalmology Language A language of the resource EN https://www.socictopen.socict.org/files/original/caaac04e334fa82138b021b3a6fa8b09.pdf 2f277eb81c973070315245a1abbf8783 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A socioeconomic analysis of Ethiopian migrant entrepreneurs in South Africa Creator An entity primarily responsible for making the resource Zeleke Worku Description An account of the resource The objective of study was to assess and evaluate factors that affect entrepreneurial activities carried out by formal and informal migrant entrepreneurs from Ethiopia who conduct business operations in the nine provinces of South Africa. The study was descriptive and exploratory in nature. The design of the study was descriptive and cross-sectional. Data were collected from a stratified random sample of 3,045 migrant entrepreneurs from Ethiopia who conduct business in the nine provinces of South Africa. Stratified random sampling was used for the selection of eligible entrepreneurs. The study found that about 76% of businesses operated by migrant entrepreneurs from Ethiopia were profitable, whereas the remaining 24% of businesses were not profitable. About 32% of entrepreneurs were attracted to South Africa due to better infrastructural facilities. About 25% of entrepreneurs were attracted to South Africa due to better socioeconomic conditions. About 78% of migrant entrepreneurs had conducted business in South Africa for five years or more at the time of data collection. About 34% of businesses paid tax to the South African Revenue Service (SARS) on a regular basis. About 38% of businesses employed at least one South African in their businesses. About 85% of entrepreneurs stated that they had good working relationships with members of the various local communities in South Africa. Date A point or period of time associated with an event in the lifecycle of the resource 2018 Subject The topic of the resource economic analysis, Ethiopian migrant entrepreneurs, logit analysis, South Africa Identifier An unambiguous reference to the resource within a given context DOI: 10.21511/ppm.16(2).2018.40 Source A related resource from which the described resource is derived Problems and Perspectives in Management Publisher An entity responsible for making the resource available LLC CPC "Business Perspectives"" Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Business Language A language of the resource EN https://www.socictopen.socict.org/files/original/f3927b33a6578f92eac7b7e144a70429.pdf a721ed03ec8bf634a26cbd52d057d3ec Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource COVID-19: A New Virus as a Potential Rapidly Spreading in the Worldwide Creator An entity primarily responsible for making the resource Fariba Rezaeetalab, Mahnaz Mozdourian, Mahnaz Amini, Zahra Javid Arabshahi, Farzaneh Akbari Description An account of the resource Covid-19 is a novel virus with high affinity to spread in the community. In December 2019, it was first identified in Wuhan, China. The symptoms are non-specific, so fever, cough, dyspnea, are prominent features. Respiratory failure and mortality have also been reported. The most common lung CT scan findings are bilateral ground glass opacities. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource COVID-19, Mortality, respiratory symptom Identifier An unambiguous reference to the resource within a given context DOI: 10.22038/jctm.2020.46924.1264 Source A related resource from which the described resource is derived Journal of Cardio-Thoracic Medicine Publisher An entity responsible for making the resource available Mashhad University of Medical Sciences Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Diseases of the circulatory (Cardiovascular) system, Diseases of the respiratory system Language A language of the resource EN https://www.socictopen.socict.org/files/original/3ff2f8a21c150628a1fd44159f084793.pdf 24a4cecf52abe90a1519068b9e15170d Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource MAVS-mediated apoptosis and its inhibition by viral proteins. Creator An entity primarily responsible for making the resource Yu Lei, Chris B. Moore, Rachael M. Liesman, Brian P O'Connor, Daniel T Bergstralh, Zhijian J. Chen, Raymond J Pickles, Jenny P.-Y. Ting Description An account of the resource BACKGROUND:Host responses to viral infection include both immune activation and programmed cell death. The mitochondrial antiviral signaling adaptor, MAVS (IPS-1, VISA or Cardif) is critical for host defenses to viral infection by inducing type-1 interferons (IFN-I), however its role in virus-induced apoptotic responses has not been elucidated. PRINCIPAL FINDINGS:We show that MAVS causes apoptosis independent of its function in initiating IFN-I production. MAVS-induced cell death requires mitochondrial localization, is caspase dependent, and displays hallmarks of apoptosis. Furthermore, MAVS(-/-) fibroblasts are resistant to Sendai virus-induced apoptosis. A functional screen identifies the hepatitis C virus NS3/4A and the Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) nonstructural protein (NSP15) as inhibitors of MAVS-induced apoptosis, possibly as a method of immune evasion. SIGNIFICANCE:This study describes a novel role for MAVS in controlling viral infections through the induction of apoptosis, and identifies viral proteins which inhibit this host response. Date A point or period of time associated with an event in the lifecycle of the resource 2009 Identifier An unambiguous reference to the resource within a given context DOI: 10.1371/journal.pone.0005466 Source A related resource from which the described resource is derived PLoS ONE Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Science, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/507b4f1b372325413a2a051afc1ec7e0.pdf 0deb71222d0e4d2a378d883413778de8 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource 2019 Coronavirus Pandemic in Turkey and Across the World Creator An entity primarily responsible for making the resource Ahmet Görkem ER, Serhat Ünal Description An account of the resource The novel coronavirus, which was called 2019-nCoV at the beginning of the outbreak, was named SARS-CoV-2 later. The clinical disease caused by the virus was also called Coronavirus disease 2019 (COVID-19). World Health Organization declared COVID-19 a global pandemic on 11.03.2020. As of 26.03.2020, there have been 462.684 confirmed cases and 20.834 deaths globally, and these numbers are expected to increase in the coming days. The dynamics of virus spread are investigated with various models and outbreakparameters such as incubation time and basic reproduction number (R0) is tried to be illuminated. According to official numbers, as of 03.26.2020, there have also been 3629 cases and 75 deaths in Turkey. COVID-19 Guideline prepared by the Ministry of Health of the Republic of Turkey is constantly updated with additional prevention and treatment strategies. Various predictions are made for the future course of the pandemic, and the contribution of the spread of the virus in Africa and seasonal changes on this issue has been investigated. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource SARS-CoV-2, coronavirus pandemic, COVID-19, Turkey Identifier An unambiguous reference to the resource within a given context DOI: 10.5578/flora.202001 Source A related resource from which the described resource is derived Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi Publisher An entity responsible for making the resource available Bilimsel Tip Yayinevi Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Microbiology Language A language of the resource EN, TR https://www.socictopen.socict.org/files/original/2a69569751614a32edf694ee340e5b42.pdf 8535ccd14c71a527cde3a7a98b407284 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Advice on Standardized Diagnosis and Treatment for Spinal Diseases during the Coronavirus Disease 2019 Pandemic Creator An entity primarily responsible for making the resource Jun Zou, Hao YU, Dawei Song, Junjie Niu, Huilin Yang Description An account of the resource Coronavirus disease 2019 (COVID-19) outbreak started in December 2019 that caused difficulties for clinical work. Practical work experience in our spinal outpatient and emergency department during the COVID-19 pandemic is summarized in this article, with combined evidence-based medical evidence to explore a standardized process of diagnosis and treatment for spinal diseases. Outpatient reservation, continuous screening, triage, and isolation, first consultation accountability system, pandemic reporting system, and online revisit were strictly followed. We hope that our experience in prevention and control of COVID-19 can help spine surgeons globally in stopping the spread of COVID-19. Spine surgeons should collaborate with infection control specialists to avoid cross-infection in hospitals and optimize treatment. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource COVID-19, infection control, Spinal Diseases, disease management Identifier An unambiguous reference to the resource within a given context DOI: 10.31616/asj.2020.0122 Source A related resource from which the described resource is derived Asian Spine Journal Publisher An entity responsible for making the resource available Korean Spine Society Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/94843286ad21d86b1c5bfb42bf47b475.pdf 6b00df5496dbf47f52902bb7ba6a688e Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Investiagation of possible mechanism of eye transmission of SARS-CoV-2 based on SARS-CoV Creator An entity primarily responsible for making the resource Fu-Lai Niu^*, Na-Na Ku^*, Yi Sun Description An account of the resource SARS-CoV-2 has been spreading rapidly since its outbreak in December 2019.Understanding its epidemiological characteristics, especially cutting off transmission routes, is crucial to controlling the spread of the disease. In the study of transmission pathway, the issue of whether SARS-CoV-2 is transmitted through ocular surface tissue has also aroused concerns, but there are still no clinically confirmed cases and laboratory evidence of its infection through ocular surface tissue. New research suggests that the SARS-CoV-2 belongs to the same genus as SARS coronavirus(SARS-CoV), and that it enters cells in the same way as SARS-CoV. This paper reviews the research on SARS-CoV to investigate the possible mechanism of eye transmission of SARS-CoV-2. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource SARS-coronavirus, SARS-CoV-2, eye transmission, mechanism Identifier An unambiguous reference to the resource within a given context DOI: 10.3980/j.issn.1672-5123.2020.4.35 Source A related resource from which the described resource is derived Guoji Yanke Zazhi Publisher An entity responsible for making the resource available Press of International Journal of Ophthalmology (IJO PRESS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Ophthalmology Language A language of the resource EN https://www.socictopen.socict.org/files/original/bc039e0842f00de58bedc2d219a07ee9.pdf 85ac49b7e1aa109669533c69b73a52e7 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The Battle Against COVID-19: Where Do We Stand Now? Creator An entity primarily responsible for making the resource Manica Negahdaripour Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource COVID-19, coronavirus Identifier An unambiguous reference to the resource within a given context DOI: 10.30476/ijms.2020.46357 Source A related resource from which the described resource is derived Iranian Journal of Medical Sciences Publisher An entity responsible for making the resource available Shiraz University of Medical Sciences Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine (General) Language A language of the resource EN