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Tetranucleotide usage highlights genomic heterogeneity among mycobacteriophages [version 2; referees: 2 approved]
Background The genomic sequences of mycobacteriophages, phages infecting mycobacterial hosts, are diverse and mosaic. Mycobacteriophages often share little nucleotide similarity, but most of them have been grouped into lettered clusters and further…
Position: 14048 (21 views)
Modified Vaccinia Virus Ankara (MVA) as Production Platform for Vaccines against Influenza and Other Viral Respiratory Diseases
Respiratory viruses infections caused by influenza viruses, human parainfluenza virus (hPIV), respiratory syncytial virus (RSV) and coronaviruses are an eminent threat for public health. Currently, there are no licensed vaccines available for hPIV,…
Position: 15123 (20 views)
SARS-COV INDUCE L’ESPRESSIONE DI IFN-α E-γ IN PBMC DA DONATORI SANI ANCHE IN ASSENZA DI REPLICAZIONE VIRALE
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Position: 9420 (26 views)
Acute respiratory viral infections in pediatric cancer patients undergoing chemotherapy
OBJECTIVE: to estimate the prevalence of infection by respiratory viruses in pediatric patients with cancer and acute respiratory infection (ARI) and/or fever. METHODS: cross-sectional study, from January 2011 to December 2012. The secretions of…
Position: 10205 (25 views)
Peritonite infecciosa felina: 13 casos Feline infectious peritonitis: 13 cases
Numa pesquisa realizada em tecidos de 638 gatos necropsiados, foram encontrados 13 casos (2,03%) de peritonite infecciosa felina. Oito desses casos (61,53%) eram da forma efusiva ou úmida, e 5 apresentavam a forma seca ou não-efusiva da doença. A…
Position: 1997 (50 views)
Russian Arctic Petroleum Resources Ressources pétrolières de l’Arctique russe
The Arctic continental shelf is believed to be the area with the highest unexplored potential for oil and gas as well as for unconventional hydrocarbon resources such as gas hydrates. Despite a common view that the Arctic has plentiful of hydrocarbon…
Position: 4542 (36 views)
Molecular Characterizations of Subcellular Localization Signals in the Nucleocapsid Protein of Porcine Epidemic Diarrhea Virus
The nucleolus is a dynamic subnuclear structure, which is crucial to the normal operation of the eukaryotic cell. The porcine epidemic diarrhea virus (PEDV), coronavirus nucleocapsid (N) protein, plays important roles in the process of virus…
Position: 5864 (32 views)
Regulatory T Cells in Arterivirus and Coronavirus Infections: Do They Protect Against Disease or Enhance it?
Regulatory T cells (T<sub>regs</sub>) are a subset of T cells that are responsible for maintaining peripheral immune tolerance and homeostasis. The hallmark of T<sub>regs</sub> is the expression of the forkhead box P3 (FoxP3)…
Position: 12051 (23 views)
On the etiology of an outbreak of winter dysentery in dairy cows in Brazil Sobre a etiologia de um surto de disenteria de inverno em vacas leiteiras no Brasil
Winter dysentery (WD) is a seasonal infectious disease described worldwide that causes a marked decrease in milk production in dairy cows. In the Northern hemisphere, where the disease is classically recognized, bovine coronavirus (BCoV) has been…
Position: 13017 (22 views)
The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection
ADP-ribosylation is a common posttranslational modification that may have antiviral properties and impact innate immunity. To regulate this activity, macrodomain proteins enzymatically remove covalently attached ADP-ribose from protein targets. All…
Position: 1132 (59 views)