154 10 20655 https://www.socictopen.socict.org/files/original/6341858e2bcb77d1fb99eb8a77cb3159.pdf a31a2d7b4e2b07f292bb23e4fc66ea39 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Peru a possible scenario for coinfection between COVID-19 and dengue Creator An entity primarily responsible for making the resource Franklin Rouselbel Correa Prieto Description An account of the resource Sr. Editor, la infección causada por SARS-Cov-2; llamada por la Organización Mundial de la Salud el 11 febrero del 2020 (1), enfermedad por COVID-19; ha sido declara actualmente como una pandemia por la OMS, afectando en este momento a 184 países, siendo una enfermedad emergente (2,3). Actualmente, hay 1.324.907 infectados con 73.703 decesos en el mundo (3,4). En Latinoamérica han superado 24.544 casos (4); siendo Perú uno de los primeros países latinoamericanos en adoptar medidas de contención a esta pandemia (5,6). Sin embargo, habiendo transcurrido veintidós (22) días de aislamiento social obligatorio, hasta la fecha se ha registrado 2561 casos en el territorio peruano, con 92 decesos, 387 hospitalizados y 89 pacientes en la Unidad de Cuidados Intensivos, con necesidad de ventilación mecánica (7). Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context DOI: 10.5281/zenodo.3743470 Source A related resource from which the described resource is derived Kasmera Publisher An entity responsible for making the resource available Universidad de Zulia Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Arctic medicine. Tropical medicine, Public aspects of medicine Language A language of the resource ES https://www.socictopen.socict.org/files/original/c3c81008dbb46d066558e16631092916.pdf 183e6d61c60021980b23149d88425ad3 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Disease 2019: Review of Current Literatures Creator An entity primarily responsible for making the resource Adityo Susilo, Cleopas Martin Rumende, Ceva Wicaksono Pitoyo, Widayat Djoko Santoso, Mira Yulianti, Heri Kurniawan, Robert Sinto, Gurmeet Singh, Leonard Nainggolan, Erni Juwita Nelwan, Lie Khie Chen, Alvina Widhani, Edwin Wijaya, Bramantya Wicaksana, Maradewi Maksum, Firda Annisa, Cynthia Olivia Maurine Jasirwan, Evy Yunihastuti Description An account of the resource In early 2020, the world was caught off guard by the outbreak of unknown pneumonia that began in Wuhan, Hubei Province. It spread rapidly throughout more than 180 countries. This outbreak is named coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The spread of this disease has had wide social and economic impacts. There are many controversies surrounding this disease, such as diagnosis, management, and prevention. Therefore, we conducted a review of current literatures related to COVID-19 that have been published since the beginning of 2020. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource COVID-19, Pandemic, SARS-CoV-2, Wuhan Identifier An unambiguous reference to the resource within a given context DOI: http://dx.doi.org/10.7454/jpdi.v7i1.415 Source A related resource from which the described resource is derived Jurnal Penyakit Dalam Indonesia Publisher An entity responsible for making the resource available Department of Internal Medicine, Faculty of Medicine Universitas Indonesia-Cipto Mangunkusumo Hospital Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Internal medicine Language A language of the resource ID https://www.socictopen.socict.org/files/original/140e2b4ff5e2542bcf350d09963328f5.pdf 7e6710f81553a54c98103cb68521dbd5 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource No evidence supports the use of ether and chloroform inhalation for treating COVID-19 Creator An entity primarily responsible for making the resource Paulo Ricardo Martins-Filho, Victor Santana Santos Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context DOI: 10.26633/RPSP.2020.41 Source A related resource from which the described resource is derived Revista Panamericana de Salud Pública Publisher An entity responsible for making the resource available Pan American Health Organization Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Arctic medicine. Tropical medicine, Public aspects of medicine, Medicine Language A language of the resource EN, ES, PT https://www.socictopen.socict.org/files/original/f259a6e56628fe512b73d20c26d6403a.pdf 8fe64bfaa699d952176e76cae3cc3c35 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Transmissibility of MERS-CoV Infection in Closed Setting, Riyadh, Saudi Arabia, 2015 Creator An entity primarily responsible for making the resource Maria D. Van Kerkhove, Sadoof Alaswad, Abdullah Assiri, Ranawaka A.P.M. Perera, Malik Peiris, Hassan E. El Bushra, Abdulaziz A. Bin Saeed Description An account of the resource To investigate a cluster of Middle East respiratory syndrome (MERS) cases in a women-only dormitory in Riyadh, Saudi Arabia, in October 2015, we collected epidemiologic information, nasopharyngeal/oropharyngeal swab samples, and blood samples from 828 residents during November 2015 and December 2015–January 2016. We found confirmed infection for 19 (8 by reverse transcription PCR and 11 by serologic testing). Infection attack rates varied (2.7%–32.3%) by dormitory building. No deaths occurred. Independent risk factors for infection were direct contact with a confirmed case-patient and sharing a room with a confirmed case-patient; a protective factor was having an air conditioner in the bedroom. For 9 women from whom a second serum sample was collected, antibodies remained detectable at titers >1:20 by pseudoparticle neutralization tests (n = 8) and 90% plaque-reduction neutralization tests (n = 2). In closed high-contact settings, MERS coronavirus was highly infectious and pathogenicity was relatively low. Date A point or period of time associated with an event in the lifecycle of the resource 2019 Subject The topic of the resource MERS-CoV, Middle East respiratory syndrome coronavirus, Human-to-human transmission, seroepidemiology, Outbreak investigation, Viruses Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid2510.190130 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/3a248a2f8fb83fe20babb18a1da6fc3a.pdf bd9f2928676038ac8e60c38c3a1336a0 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Covid-19: Physical Distancing Will Make Science Closer to Citizen Participation in Decision Making Creator An entity primarily responsible for making the resource Stefano Cinti Description An account of the resource Nowadays, social distancing is mandatory in various countries worldwide. It is defined as a non-pharmaceutical interventions for preventing the spread of COVID-19, by maintaining a distance among people and reducing the frequency of contacts with each other. However, the correct definition, as reported somewhere, should be physical distancing. Populations are “socially” close, citizens are experimenting novel approaches of communication, and novel way to help. Of course, in the era of social networks, everybody is enabled to get in touch, even with people that were missing since lot of time. The velocity of how life goes, the necessity of getting results, the demonstration of own value and the invention of brand-new strategies to overcome the generic “everyday” issues, covering all the fields such as family, job, friends, etc., are facing with a pandemic monster. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource COVID-19, social distancing, communication, Solution, connection Identifier An unambiguous reference to the resource within a given context DOI: 10.13128/Substantia-900 Source A related resource from which the described resource is derived Substantia Publisher An entity responsible for making the resource available Firenze University Press Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Chemistry, History (General) and history of Europe Language A language of the resource EN https://www.socictopen.socict.org/files/original/5e4c9ab4531533eb1d4364dcd13948c3.pdf ce1fd87bbbd06476bf6d2d23ff4d861f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Data-based analysis, modelling and forecasting of the COVID-19 outbreak. Creator An entity primarily responsible for making the resource Cleo Anastassopoulou, Lucia Russo, Athanasios Tsakris, Constantinos Siettos Description An account of the resource Since the first suspected case of coronavirus disease-2019 (COVID-19) on December 1st, 2019, in Wuhan, Hubei Province, China, a total of 40,235 confirmed cases and 909 deaths have been reported in China up to February 10, 2020, evoking fear locally and internationally. Here, based on the publicly available epidemiological data for Hubei, China from January 11 to February 10, 2020, we provide estimates of the main epidemiological parameters. In particular, we provide an estimation of the case fatality and case recovery ratios, along with their 90% confidence intervals as the outbreak evolves. On the basis of a Susceptible-Infectious-Recovered-Dead (SIDR) model, we provide estimations of the basic reproduction number (R0), and the per day infection mortality and recovery rates. By calibrating the parameters of the SIRD model to the reported data, we also attempt to forecast the evolution of the outbreak at the epicenter three weeks ahead, i.e. until February 29. As the number of infected individuals, especially of those with asymptomatic or mild courses, is suspected to be much higher than the official numbers, which can be considered only as a subset of the actual numbers of infected and recovered cases in the total population, we have repeated the calculations under a second scenario that considers twenty times the number of confirmed infected cases and forty times the number of recovered, leaving the number of deaths unchanged. Based on the reported data, the expected value of R0 as computed considering the period from the 11th of January until the 18th of January, using the official counts of confirmed cases was found to be ∼4.6, while the one computed under the second scenario was found to be ∼3.2. Thus, based on the SIRD simulations, the estimated average value of R0 was found to be ∼2.6 based on confirmed cases and ∼2 based on the second scenario. Our forecasting flashes a note of caution for the presently unfolding outbreak in China. Based on the official counts for confirmed cases, the simulations suggest that the cumulative number of infected could reach 180,000 (with a lower bound of 45,000) by February 29. Regarding the number of deaths, simulations forecast that on the basis of the up to the 10th of February reported data, the death toll might exceed 2,700 (as a lower bound) by February 29. Our analysis further reveals a significant decline of the case fatality ratio from January 26 to which various factors may have contributed, such as the severe control measures taken in Hubei, China (e.g. quarantine and hospitalization of infected individuals), but mainly because of the fact that the actual cumulative numbers of infected and recovered cases in the population most likely are much higher than the reported ones. Thus, in a scenario where we have taken twenty times the confirmed number of infected and forty times the confirmed number of recovered cases, the case fatality ratio is around ∼0.15% in the total population. Importantly, based on this scenario, simulations suggest a slow down of the outbreak in Hubei at the end of February. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context DOI: 10.1371/journal.pone.0230405 Source A related resource from which the described resource is derived PLoS ONE Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Science, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/a177c03bfc3c10aad3d09fd876dbd12f.pdf d04d4c441a5efb080dcd9876842b913d Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Traditional Chinese herbal medicine for treating novel coronavirus (COVID-19) pneumonia: protocol for a systematic review and meta-analysis Creator An entity primarily responsible for making the resource Yuxi Li, Xiao-bo Liu, Liuxue Guo, Juan Li, Dongling Zhong, Yonggang Zhang, Mike Clarke, Rong-jiang JIN Description An account of the resource Abstract Background A new type of coronavirus, novel coronavirus (COVID-19), is causing an increasing number of cases of pneumonia and was declared a Public Health Emergency of International Concern by the World Health Organization on 30 January 2020. The virus first appeared in Wuhan, China, in late December 2019, and traditional Chinese herbal medicine is being used for its treatment. This systematic review and meta-analysis will assess studies of the effects of traditional Chinese herbal medicine in COVID-19 pneumonia. Methods We will search electronic databases including PubMed, Embase, the Cochrane Central Register of Controlled Trials (CENTRAL), Chinese Biomedical Literature Database (CBM), China National Knowledge Infrastructure (CNKI), Chinese Science and Technology Periodical Database (VIP), and Wanfang database using keywords related to COVID-19 and traditional Chinese herbal medicine. Reference lists of relevant trials and reviews will be searched. We will manually search gray literature, such as conference proceedings and academic degree dissertations, and trial registries. Two independent reviewers will screen studies (XL and DZ), extract data (YL and LG), and evaluate risk of bias (YL and DZ). Data analysis will be conducted using the Review Manager software (version 5.3.5) and R software (version 3.6.1). Statistical heterogeneity will be assessed using a standard chi-square test with a significance level of P < 0.10. Biases associated with study size (e.g., publication bias) will be investigated using funnel plots, Egger’s test and Begg’s test, and Trim and Fill analysis. Discussion This study will provide a high-quality synthesis of the effects of traditional Chinese herbal medicine for COVID-19. The use of traditional Chinese herbal medicine for treatment or prevention of these novel viral infections affecting the pneumonia will be investigated. Systematic review registration PROSPERO registration number: CRD42020168004 Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource COVID-19, coronavirus, Pneumonia, Traditional Chinese herbal medicine emerging infectious diseases, systematic review, Meta-analysis Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s13643-020-01343-4 Source A related resource from which the described resource is derived Systematic Reviews Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/831b5e79b8312861cbdf640dc176d46d.pdf 52b83bd427a0caf35bcf002c485f3e55 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Convocatoria de autores para número monográfico: La construcción de un nuevo paradigma post pandemia Creator An entity primarily responsible for making the resource Oscar R. Gómez Description An account of the resource La Revista Científica Arbitrada de la Fundación MenteClara Internacional (RCAFMC) convoca a la presentación de trabajos de investigación enfocados en la construcción de un nuevo paradigma de sujeto y las consecuencias individuales, sociales, políticas y económicas de la pandemia COVID-19 que busquen responder, entre otras, a las siguientes preguntas: ¿Qué inequidades se visibilizaron con la pandemia?, ¿Qué nuevos derechos se constituyeron?, ¿Cuál es el lugar de la filosofía en estos eventos?, ¿Cómo repensar la ciencia y su organización, para responder a estas situaciones?, ¿Qué discursos sociales, políticos, morales y religiosos, sustentaron diversas formas de pensar la pandemia? y ¿Que instrumentos didácticos pueden colaborar en la construcción de un modelo de pensamiento superador del sujeto previo a la pandemia COVID-19? Esta convocatoria tiene como objeto debatir, articular conceptos y producir nuevas herramientas académicas para obtener una visión clara del posible nuevo sistema de pensamiento post pandemia, reuniendo en un foro común a intelectuales de diferentes disciplinas que contribuyan a solucionar las consecuencias del COVID-19 en los individuos y su mundo de relaciones sociales, políticas y económicas. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource COVID-19, pandemia, convocatoria, Monográfico Identifier An unambiguous reference to the resource within a given context DOI: 10.32351/rca.v5.150 Source A related resource from which the described resource is derived Revista Científica Arbitrada de la Fundación MenteClara Publisher An entity responsible for making the resource available Fundación MenteClara Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Philosophy. Psychology. Religion, Buddhism Language A language of the resource EN, ES https://www.socictopen.socict.org/files/original/e78db1e78508fae5f65bc59a9d2fb1d4.pdf 1fb8263384732cf883978ead84511fda Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource COVID-19: The new pandemic with many lessons and new challenges. Narrative Review Creator An entity primarily responsible for making the resource Nereida Josefina Valero Cedeño, Jhon Bryan Mina-Ortiz, Teresa Isabel Veliz-Castro, Karina Maricela Merchán-Villafuerte, Armindo José Perozo Mena Description An account of the resource The new coronavirus (2019-nCoV, SARS-CoV-2 or COVID-19), which so far has affected more than 180 countries on almost every continent, was declared a pandemic by the World Health Organization. its global reach and to date, has exceeded one million infected cases, of which 5.54% have been fatal. The emergence of this disease has been explained by the presence of an unknown human coronavirus with increased virulence factors. The exponentially increasing number of cases in the world reflects in part the rapid transmission of COVID-19, which translates into a severe test for the health systems of the most affected countries. The challenges that this pandemic has represented, many have been based on the lessons learned from the SARS pandemic in 2003 and given the genomic similarity of this new strain of coronavirus, it has been designated as SARS-CoV-2. However, the like, there are many questions still to be answered, especially with regard to transmission mechanisms. Having detailed and accurate data will make it possible to understand and monitor the scope of this pandemic and strengthen prevention and response efforts, since the treatments are so far experimental and the vaccine may be available in the medium or long term. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource COVID-19, pandemias, SARS-CoV-2, transmisión de enfermedad infecciosa Identifier An unambiguous reference to the resource within a given context DOI: 10.5281/zenodo.3745322 Source A related resource from which the described resource is derived Kasmera Publisher An entity responsible for making the resource available Universidad de Zulia Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Arctic medicine. Tropical medicine, Public aspects of medicine Language A language of the resource ES https://www.socictopen.socict.org/files/original/e14ed865705d8849611340c2290b574c.pdf 5e040582ccd22fb9785ba053b901a82f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Comparison of motif-based and whole-unique-sequence-based analyses of phage display library datasets generated by biopanning of anti-Borrelia burgdorferi immune sera. Creator An entity primarily responsible for making the resource Yurij Ionov, Artem S Rogovskyy Description An account of the resource Detection of protection-associated epitopes via reverse vaccinology is the first step for development of subunit vaccines against microbial pathogens. Mapping subunit vaccine targets requires high throughput methods, which would allow delineation of epitopes recognized by protective antibodies on a large scale. Phage displayed random peptide library coupled to Next Generation Sequencing (PDRPL/NGS) is the universal platform that enables high-yield identification of peptides that mimic epitopes (mimotopes). Despite being unsurpassed as a tool for discovery of polyclonal serum mimotopes, the PDRPL/NGS is far inferior as a quantitative method of immune response. Difficult-to-control fluctuations in amounts of antibody-bound phages after rounds of selection and amplification diminish the quantitative capacity of the PDRPL/NGS. In an attempt to improve the accuracy of the PDRPL/NGS method, we compared the discriminating capacity of two approaches for PDRPL/NGS data analysis. The whole-unique-sequence-based analysis (WUSA) involved generation of 7-mer peptide profiles and comparison of the numbers of sequencing reads for unique peptide sequences between serum samples. The motif-based analysis (MA) included identification of 4-mer consensus motifs unifying unique 7-mer sequences and comparison of motifs between serum samples. The motif comparison was based not on the numbers of sequencing reads, but on the numbers of distinct 7-mers constituting the motifs. Our PDRPL/NGS datasets generated from biopanning of protective and non-protective anti-Borrelia burgdorferi sera of New Zealand rabbits were used to contrast the two approaches. As a result, the principle component analyses (PCA) showed that the discriminating powers of the WUSA and MA were similar. In contrast, the unsupervised hierarchical clustering obtained via the MA classified the preimmune, non-protective, and protective sera better than the WUSA-based clustering. Also, a total number of discriminating motifs was higher than that of discriminating 7-mers. In sum, our results indicate that MA approach improves the accuracy and quantitative capacity of the PDRPL/NGS method. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context DOI: 10.1371/journal.pone.0226378 Source A related resource from which the described resource is derived PLoS ONE Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Science, Medicine Language A language of the resource EN