183 10 20655 https://www.socictopen.socict.org/files/original/118b2eb88a1566d68d9f52f710a9b140.pdf f92f40ec6568317bc8178b99a3589bbd Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Psychosocial Impact of SARS Creator An entity primarily responsible for making the resource Hector W. H. Tsang, Rhonda J. Scudds, Ellen Y.L. Chan Date A point or period of time associated with an event in the lifecycle of the resource 2004 Subject The topic of the resource SARS, psychosocial impact, family burden, Letter, Hong Kong Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid1007.040090 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/fd13cbee67e5ef12bdace54a1e21daaf.pdf 7e3f770d8e10d6f5f7724db447fdd2a6 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Virus-specific RNA and Antibody from Convalescent-phase SARS Patients Discharged from Hospital Creator An entity primarily responsible for making the resource Hoe-Nam Leong, Kwai-Peng Chan, Ali S Khan, Lynette Oon, Su Yun Se Thoe, Xin Lai Bai, Daniel Yeo, Yee Sin Leo, Brenda Ang, Thomas G. Ksiazek, Ai Ee Ling Description An account of the resource Severe acute respiratory syndrome (SARS) is caused by a novel coronavirus (SARS-CoV). In a longitudinal cross-sectional study, we determined the prevalence of virus in bodily excretions and time of seroconversion in discharged patients with SARS. Conjunctival, throat, stool, and urine specimens were collected weekly from 64 patients and tested for SARS-CoV RNA by real-time polymerase chain reaction; serum samples were collected weekly and tested for SARS-CoV antibody with indirect enzyme immunoassay and immunofluorescence assay. In total, 126 conjunctival, 124 throat swab, 116 stool, and 124 urine specimens were analyzed. Five patients had positive stool samples, collected weeks 5–9. Two patients seroconverted in weeks 7 and 8; the others were seropositive at the first serum sample collection. In this study, 5 (7.8%) of 64 patients continued to shed viral RNA in stool samples only, for up to week 8 of illness. Most seroconversions occurred by week 6 of illness. Date A point or period of time associated with an event in the lifecycle of the resource 2004 Subject The topic of the resource SARS, Convalescence, Polymerase Chain Reaction, serology, ELISA, Indirect immunofluorescence assay Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid1010.040026 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/5351f9f92e94ea212b5250a90485841e.pdf 5dbcf2a9938e45b0da00e305ea194acb Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Long-term SARS Coronavirus Excretion from Patient Cohort, China Creator An entity primarily responsible for making the resource Li-Qun Fang, Fang Tang, Arnaud Fontanet, Lin Zhan, Qiu-Min Zhao, Pan-He Zhang, Xiaoming Wu, Shu-Qing Zuo, Laurence Baril, Astrid Vabret, Zhong-Tao Xin, Yiming Shao, Hong Yang, Wu-Chun Cao Description An account of the resource This study investigated the long-term excretion of severe acute respiratory syndrome–associated coronavirus in sputum and stool specimens from 56 infected patients. The median (range) duration of virus excretion in sputa and stools was 21 (14–52) and 27 (16–126) days, respectively. Coexisting illness or conditions were associated with longer viral excretion in stools. Date A point or period of time associated with an event in the lifecycle of the resource 2004 Subject The topic of the resource dispatch, severe acute respiratory syndrome, Epidemiology, cohort, Transmission, diagnosis Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid1010.040297 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/f3cea7986af4554364a6cd783d629847.pdf a94255aced57fc3fe87ba6556eae5ba1 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource SARS in Teaching Hospital, Taiwan Creator An entity primarily responsible for making the resource Yee-Chun Chen, Ming-Fong Chen, Shuen-Zen Liu, James C. Romeis, Yuan-Teh Lee Date A point or period of time associated with an event in the lifecycle of the resource 2004 Subject The topic of the resource Letter, SARS, hospital management, Taiwan Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid1010.040356 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/5f339aefd40bc4e1a224e3a06d6cd82a.pdf e5a1900b1dd3599f4779ed51ad6d72fe Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Modification effect of fenofibrate therapy, a longitudinal epigenomic-wide methylation study of triglycerides levels in the GOLDN study Creator An entity primarily responsible for making the resource Runmin Wei, Yanyan Wu Description An account of the resource Abstract Background Identification of interactions between epigenetic factors and treatments might lead to personalized intervention of diseases. This paper aims to examine the modification effect of fenofibrate therapy on the association of methylation levels and fasting blood triglycerides (TG), and the related biological pathways among methylation sites. Results Mixed-effects models were employed to assess pre- and posttreatment associations and drug modification effects simultaneously. Five cytosine-phosphate-guanine (CpG) sites were found to be associated with TG levels before and after the fenofibrate therapy: cg00574958, cg17058475, and cg01082498 on CPT1A gene, chromosome 11; cg03725309 on SARS, chromosome 1; and cg06500161 on ABCG1, chromosome 21. In addition, fenofibrate therapy modified the methylation levels on the following 4 CpG sites: cg20015535 (gene EGLN1, chromosome 1); cg24870738 (gene RNF220, chromosome 1); cg06891775 (gene LOC283050, chromosome 10); and cg00607630 (gene USP7, chromosome 16). Further, gene set enrichment analysis (GSEA) identified cancer- and metabolism-related pathways that were associated with TG-related CpG sites. Conclusions We identified modification effects of fenofibrate on the associations between blood TG levels and several CpG sites. Pathway enrichment analysis indicated the alternations in some metabolism and cancer-related pathways. Our findings have important implications for future research in pharmacoepigenetics and personalized medicine. Date A point or period of time associated with an event in the lifecycle of the resource 2018 Subject The topic of the resource methylation, TG, repeated-measures, mixed models, interaction, GSEA Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s12863-018-0643-6 Source A related resource from which the described resource is derived BMC Genetics Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Genetics Language A language of the resource EN https://www.socictopen.socict.org/files/original/72eae65d164332ea5ec8356a6d9217dd.pdf 5936b2fcf33505223477ec2aa565bc5a Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Mutation in Spike Protein Cleavage Site and Pathogenesis of Feline Coronavirus Creator An entity primarily responsible for making the resource Beth N. Licitra, Jean K. Millet, Andrew D. Regan, Brian S. Hamilton, Vera D. Rinaldi, Gerald E. Duhamel, Gary R. Whittaker Description An account of the resource Feline coronaviruses (FCoV) exist as 2 biotypes: feline enteric coronavirus (FECV) and feline infectious peritonitis virus (FIPV). FECV causes subclinical infections; FIPV causes feline infectious peritonitis (FIP), a systemic and fatal disease. It is thought that mutations in FECV enable infection of macrophages, causing FIP. However, the molecular basis for this biotype switch is unknown. We examined a furin cleavage site in the region between receptor-binding (S1) and fusion (S2) domains of the spike of serotype 1 FCoV. FECV sequences were compared with FIPV sequences. All FECVs had a conserved furin cleavage motif. For FIPV, there was a correlation with the disease and >1 substitution in the S1/S2 motif. Fluorogenic peptide assays confirmed that the substitutions modulate furin cleavage. We document a functionally relevant S1/S2 mutation that arises when FIP develops in a cat. These insights into FIP pathogenesis may be useful in development of diagnostic, prevention, and treatment measures against coronaviruses. Date A point or period of time associated with an event in the lifecycle of the resource 2013 Subject The topic of the resource macrophage, pathology, protease, Protein Processing, Feline coronavirus, Viruses, conserved furin cleavage motif Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid1907.121094 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/b1a63b6e6cf68baefb05de4b719d51c8.pdf b5345a19adc91a9cd619dbf2033b6b1c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Lifting the Impenetrable Veil: From Yellow Fever to Ebola Hemorrhagic Fever and SARS Creator An entity primarily responsible for making the resource Sharon Bloom Date A point or period of time associated with an event in the lifecycle of the resource 2014 Subject The topic of the resource Charles Calisher, Arbovirus, arbovirology, yellow fever, Viral hemorrhagic fevers, bat-borne viruses Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid2003.131889 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/33df8fed724d79db42ffb550456c16bd.pdf d4ce4adee89bf9917aebe4bba8e898bf Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Contact Tracing for Imported Case of Middle East Respiratory Syndrome, China, 2015 Creator An entity primarily responsible for making the resource Min Kang, Tie Song, Haojie Zhong, Jie Hou, Jun Wang, Jiansen Li, Jie Wu, Jian-Feng He, Jinyan Lin, Yonghhui Zhang Description An account of the resource Confirmation of an imported case of infection with Middle East respiratory syndrome coronavirus in China triggered intensive contact tracing and mandatory monitoring. Using a hotline and surveillance video footage was effective for tracing all 110 identified contacts. Contact monitoring detected no secondary transmission of infection in China. Date A point or period of time associated with an event in the lifecycle of the resource 2016 Subject The topic of the resource Middle East respiratory syndrome, coronavirus, Viruses, contract tracing, China, Respiratory Infections Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid2209.152116 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/a10eff4c7d5449749f7052aa339c3205.pdf 45044c32afe8e6f41798a01f1b7b8bb0 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Nature of the Virus Associated with Endemic Balkan Nephropathy Creator An entity primarily responsible for making the resource Cristina Riquelme, David Escors, Javier Ortego, Carlos M. Sanchez, Branislava Uzelac-Keserovic, Konstantin Apostolov, Luis Enjuanes Date A point or period of time associated with an event in the lifecycle of the resource 2002 Subject The topic of the resource Balkan nephropathy, Bosnia and Herzegovina, Bulgaria, coronavirus, Romania, Serbia Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid0808.020042 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/0dfa4210f0950aec73721fe747b69d50.pdf cef2b4d59abad7d9c90c068aa2b1c3a7 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Review of Bats and SARS Creator An entity primarily responsible for making the resource Lin-Fa Wang, Zhengli Shi, Shuyi Zhang, Hume E. Field, Peter Daszak, Bryan T. Eaton Description An account of the resource Bats have been identified as a natural reservoir for an increasing number of emerging zoonotic viruses, including henipaviruses and variants of rabies viruses. Recently, we and another group independently identified several horseshoe bat species (genus Rhinolophus) as the reservoir host for a large number of viruses that have a close genetic relationship with the coronavirus associated with severe acute respiratory syndrome (SARS). Our current research focused on the identification of the reservoir species for the progenitor virus of the SARS coronaviruses responsible for outbreaks during 2002–2003 and 2003–2004. In addition to SARS-like coronaviruses, many other novel bat coronaviruses, which belong to groups 1 and 2 of the 3 existing coronavirus groups, have been detected by PCR. The discovery of bat SARS-like coronaviruses and the great genetic diversity of coronaviruses in bats have shed new light on the origin and transmission of SARS coronaviruses. Date A point or period of time associated with an event in the lifecycle of the resource 2006 Subject The topic of the resource emerging zoonoses, SARS, coronavirus, bats, animal reservoir, spillover Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid1212.060401 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN