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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Perception and Preference for Home-Based Telework in the COVID-19 Era: A Gender-Based Analysis in Hanoi, Vietnam</text>
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                <text>Minh  Hieu Nguyen, Jimmy Armoogum</text>
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            <description>An account of the resource</description>
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                <text>The rapid and widespread of COVID-19 has caused severe multifaceted effects on society but differently in women and men, thereby preventing the achievement of gender equality (the 5th sustainable development goal of the United Nations). This study, using data of 355 teleworkers collected in Hanoi (Vietnam) during the first social distancing period, aims at exploring how (dis)similar factors associated with the perception and the preference for more home-based telework (HBT) for male teleworkers versus female peers are. The findings show that 56% of female teleworkers compared to 45% of male counterparts had a positive perception of HBT within the social distancing period and 63% of women desired to telework more in comparison with 39% of men post-COVID-19. Work-related factors were associated with the male perception while family-related factors influenced the female perception. There is a difference in the effects of the same variables (age and children in the household) on the perception and the preference for HBT for females. For women, HBT would be considered a solution post-COVID-19 to solve the burden existing pre-COVID-19 and increasing in COVID-19. Considering gender inequality is necessary for the government and authorities to lessen the adverse effects of COVID-19 on the lives of citizens, especially female ones, in developing countries.</text>
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                <text>2021</text>
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                <text>covid-19, Pandemic, telework, social distancing, ICT, telecommuting</text>
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                <text>10.3390/su13063179</text>
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                <text>Biotemas</text>
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            <name>Publisher</name>
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                <text>Universidade Federal de Santa Catarina</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Environmental effects of industries and plants, Renewable energy sources, Environmental sciences</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>A narrative inquiry of language teachers’ perceptions and experiences in using WhatsApp during New Normal Post-Covid-19 era</text>
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                <text>Didik Murwantono, Irfan Suryana, Vicky Hidantikarnillah</text>
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                <text>The purpose of this inquiry is to explore and make sense of the stories of language teachers’ perceptions and experiences in using WhatsApp during New Normal Post-Covid-19 era. More specifically, the study is intended to understand the popularity and the usage of WhatsApp in the process of teaching and learning. To achieve the purpose of the study, a narrative inquiry is employed. Four language teachers of SMA Maarif Yogyakarta participated in this study and shared their perceptions and experiences in using WhatsApp as learning medium during New Normal Post-Covid-19 era. The online interview was used to collect information from the teachers by using Google Form. The findings of this narrative inquiry indicate that WhatsApp is a popular learning medium and the use of WhatsApp in distance online learning during New Normal Post-Covid- 19 era in SMA Maarif Yogyakarta is really effective compared to other learning media such as Google Classroom or Zoom and the language teachers give positive reactions regarding the application.</text>
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                <text>2021</text>
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                <text>New normal, Educational Technology, English Education, Learning Innovation, distance online learning</text>
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            <name>Identifier</name>
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                <text>10.30659/e.6.1.55-70</text>
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                <text>Edulite: Journal of English Education, Literature, and Culture</text>
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            <name>Publisher</name>
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                <text>Universitas Islam Sultan Agung, Semarang</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Education (General), English language</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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            <description>A name given to the resource</description>
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                <text>Modeling of residual chlorine in a drinking water network in times of pandemic of the SARS-CoV-2 (COVID-19)</text>
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                <text>Fernando García-Ávila, Alex Avilés-Añazco, Juan Ordoñez-Jara, Christian Guanuchi-Quezada, Lisveth Flores del Pino, Lía Ramos-Fernández</text>
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                <text>Abstract Due to the outbreak of the novel coronavirus disease there is a need for public water supply of the highest quality. Adequate levels of chlorine allow immediate elimination of harmful bacteria and viruses and provide a protective residual throughout the drinking water distribution network (DWDN). Therefore, a residual chlorine decay model was developed to predict chlorine levels in a real drinking water distribution network. The model allowed determining human exposure to drinking water with a deficit of residual chlorine, considering that it is currently necessary for the population to have clean water to combat coronavirus Covid 19. The chlorine bulk decay rates (kb) and the reaction constant of chlorine with the pipe wall (kw) were experimentally determined. Average kb and kw values of 3.7 d− 1 and 0.066 m d− 1 were obtained, respectively. The values of kb and kw were used in EPANET to simulate the chlorine concentrations in a DWDN. The residual chlorine concentrations simulated by the properly calibrated and validated model were notably close to the actual concentrations measured at different points of the DWDN. The results showed that maintaining a chlorine concentration of 0.87 mg L− 1 in the distribution tank, the residual chlorine values in the nodes complied with the Ecuadorian standard (0.3 mg L− 1); meanwhile, about 45% of the nodes did not comply with what is recommended by the WHO as a mechanism to combat the current pandemic (0.5 mg L− 1). This study demonstrated that residual chlorine modeling is a valuable tool for monitoring water quality in the distribution network, allowing to control residual chlorine levels in this pandemic season.</text>
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                <text>2021</text>
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                <text>covid-19, Disinfectant, Residual chlorine, Bulk decay constant, Wall decay rate</text>
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                <text>10.1186/s42834-021-00084-w</text>
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                <text>Biotemas</text>
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                <text>Universidade Federal de Santa Catarina</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Environmental technology. Sanitary engineering</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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            <description>A name given to the resource</description>
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                <text>A Call for Rethinking Schooling and Leadership in the Time of COVID-19</text>
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            <description>An entity primarily responsible for making the resource</description>
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                <text>Rodolfo Rincones, Isela Peña, Karina Chantal Canaba</text>
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            <description>An account of the resource</description>
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                <text>COVID-19 forced a sudden closure of schools, prompting a hasty and unplanned reaction of educators to deliver educational content. Inspired by Ivan Illich's book Deschooling Society, where he argues for the delivery of educational content by utilizing technology and forging intentional partnerships with parents and communities to assist in the delivery of educational content, we reflect on how these ideas impact school leadership and preparation of school leaders. This “forced” deschooling has offered educators an opportunity to rethink the true purpose of education, and redesign flexible, creative and innovative instructional strategies for delivering educational materials and knowledge, as well as rethinking the role of and preparation of educational leaders. While we do not offer quick solutions, our intent is to revisit Illich's Deschooling Society as a means to examine and question our school system introspectively and collectively.</text>
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                <text>2021</text>
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                <text>covid-19, Leadership, Ivan Illich, deschooling, principal preparation</text>
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            <description>An unambiguous reference to the resource within a given context</description>
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                <text>10.3389/feduc.2020.618075</text>
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            <description>A related resource from which the described resource is derived</description>
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                <text>Epidemiology and Health</text>
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            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="85312">
                <text>Korean Society of Epidemiology</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Education (General)</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Impact of Management Tools Supporting Industry 4.0 on the Importance of CSR during COVID-19. Generation Z</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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                <text>Szymon Cyfert, Waldemar Glabiszewski, Maciej Zastempowski</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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                <text>Taking into account the impact of the COVID-19 and adopting the assessment optics of students from Generation Z currently entering the labor market, we have made the aim of this article to provide better insight into the relationship between Industry 4.0 and corporate social responsibility. The survey was conducted in the form of an online survey in two leading universities in Poland in the field of economic education. 646 students took part in the survey. The data were analyzed using logit regression models. The results of the study suggest that the increase in the use of management solutions supporting Industry 4.0 in the wake of the COVID-19 crisis will increase the importance of the economic, social, and environmental dimensions of corporate social responsibility. Pointing to the forecasted increase importance of corporate social responsibility, we suggest linking management solutions supporting Industry 4.0 with corporate social responsibility. However, we also draw attention to the impact of individual management solutions supporting Industry 4.0 on specific Corporate Social Responsibility (CSR) dimensions.</text>
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                <text>2021</text>
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            <name>Subject</name>
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                <text>covid-19, Industry 4.0, CSR, management tools, Gen Z</text>
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            <name>Identifier</name>
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              <elementText elementTextId="85319">
                <text>10.3390/en14061642</text>
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            <description>A related resource from which the described resource is derived</description>
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                <text>Epidemiology and Health</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="85321">
                <text>Korean Society of Epidemiology</text>
              </elementText>
            </elementTextContainer>
          </element>
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                <text>Technology</text>
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              <name>Title</name>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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              </elementTextContainer>
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      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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                <text>The Impact of COVID-19 Pandemic on the Resilience of Sustainable Mobility in Sicily</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="85324">
                <text>Tiziana Campisi, Giovanni Tesoriere, Dario Ticali, Socrates Basbas, Anastasios Skoufas, Nurten Akgün</text>
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            <description>An account of the resource</description>
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                <text>The COVID-19 pandemic has resulted in unprecedented measures changing travel habits in many countries. Many users have started to prefer traveling by private cars, which is against the sustainability policies of the European cities. The necessity of gaining a deeper understanding of road users’ travel habit changes, their feelings on public transport use, and their perceptions of using sustainable urban mobility modes has emerged for future transport planning. Considering these facts, the study in this paper aimed to investigate the influence of the COVID-19 pandemic on road users’ perceptions, needs, and use of sustainable travel modes (i.e., public transport, walking, and cycling). An online survey was carried out during the period from March to May 2020 in the case study area, Sicily of Southern Italy. Regarding the population of the case study, the survey was representative, with 431 individuals. The survey included variables, namely gender, age, city of residence, private car ownership, walking and cycling frequency before and during the pandemic, public transport use frequency for leisure activities before and during the pandemic, need for remote working, and the stress and anxiety perception of using public transport during the pandemic. The analysis started with descriptive statistics and it was followed by correlation analysis in order to explore the characteristics of the dataset and relationship between variables. It was found that these were not statistically significantly correlated at a 95% confidence level. An ordinal regression model was applied for determining the predictions. The results suggested that women were less likely to walk during the pandemic than men. Participants were more likely to resume remote work even after the second phase in order to reduce their daily travel needs and keep their isolation. Participants have expressed a positive opinion on the use of micromobility during pandemic situations. These results can be considered as a basis for sustainable urban planning and a guide for decision-makers who aim to encourage the use of public transport, walking, cycling, and micromobility.</text>
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            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2020</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>covid-19, ordinal regression model, sustainable mobility modes, transport resilience</text>
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            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="85328">
                <text>10.3390/su12218829</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="85329">
                <text>Biotemas</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="85330">
                <text>Universidade Federal de Santa Catarina</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="85331">
                <text>Environmental effects of industries and plants, Renewable energy sources, Environmental sciences</text>
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            </elementTextContainer>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                <elementText elementTextId="1">
                  <text>Coronavirus</text>
                </elementText>
              </elementTextContainer>
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              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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              </elementTextContainer>
            </element>
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        </elementSet>
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    </collection>
    <itemType itemTypeId="1">
      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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    <elementSetContainer>
      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="85332">
                <text>Bioinformatic study to discover natural molecules with activity against COVID-19 [version 1; peer review: 2 approved]</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="85333">
                <text>Sweta Singh, Hector Florez</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="85334">
                <text>Background: In 2020, the world has struggled to deal with coronavirus disease 2019 (COVID-19), which started in 2019 in China and has spread throughout the globe, affecting at least 31,175,835 humans globally and claiming 962,634 lives reported till 22nd September, 2020 by the World Health Organization. The main causative agent for this disease is known as severe acute respiratory syndrome coronavirus 2 (SARS-COV-2). So far, there is no cure or proven therapeutics available till date. Therefore, we undertook this study to ﬁnd the most probable drug candidate through a bioinformatics study. Methods: Thus, we virtually screened the Zinc natural database using HTVS tool through molecular docking studies to analyze molecules recommended for the treatment of COVID-19. Results: Ramipril benzyl ester, propafenone dimer and Lariciresinol are three important drugs found from the present study due to their medicinal application which could be helpful in treating the disease. Stylopine, quillaic acid, cinobufagin, vitisinol C, segetalin A, scopolamine, 3-oxo glycyrrhetinic acid, conchinone B, lactimidomycin and cardinalins 4 are the other lead molecules that could be used as therapeutics against COVID-19 disease. Conclusions: The studied molecules could act as an effective inhibitory drug against COVID-19.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="85335">
                <text>2020</text>
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            </elementTextContainer>
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          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="85336">
                <text>10.12688/f1000research.26731.1</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="85337">
                <text>Biotemas</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="85338">
                <text>Universidade Federal de Santa Catarina</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="85339">
                <text>Science, Medicine</text>
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          <elementContainer>
            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="1">
                  <text>Coronavirus</text>
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              </elementTextContainer>
            </element>
            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
                </elementText>
              </elementTextContainer>
            </element>
          </elementContainer>
        </elementSet>
      </elementSetContainer>
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    <itemType itemTypeId="1">
      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="85340">
                <text>Optimal Containment Control Strategy of the Second Phase of the COVID-19 Lockdown in Morocco</text>
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            </elementTextContainer>
          </element>
          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="85341">
                <text>Abdessamad Tridane, Omar Zakary, Mostafa Rachik, Mustapha Lhous, El  Mostafa Magri</text>
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            </elementTextContainer>
          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="85342">
                <text>This work investigates the optimal control of the second phase of the COVID-19 lockdown in Morocco. The model consists of susceptible, exposed, infected, recovered, and quarantine compartments (SEIRQD model), where we take into account contact tracing, social distancing, quarantine, and treatment measures during the nationwide lockdown in Morocco. First, we present different components of the model and their interactions. Second, to validate our model, the nonlinear least-squares method is used to estimate the model’s parameters by fitting the model outcomes to real data of the COVID-19 in Morocco. Next, to investigate the impact of optimal control strategies on this pandemic in the country. We also give numerical simulations to illustrate and compare the obtained results with the actual situation in Morocco.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="85343">
                <text>2020</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="85344">
                <text>covid-19, Optimal control, treatment, contact-tracing, lockdown</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="85345">
                <text>10.3390/app10217559</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="85346">
                <text>Epidemiology and Health</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="85347">
                <text>Korean Society of Epidemiology</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="85348">
                <text>Biology (General), Chemistry, Engineering (General). Civil engineering (General), Technology, Physics</text>
              </elementText>
            </elementTextContainer>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                <elementText elementTextId="1">
                  <text>Coronavirus</text>
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              </elementTextContainer>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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              </elementTextContainer>
            </element>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="85349">
                <text>Healthcare Worker&amp;rsquo;s Mental Health During the Epidemic Peak of COVID-19 [Letter]</text>
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            </elementTextContainer>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="85350">
                <text>Nugroho HSW, Acob JRU, Martiningsih W</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="85351">
                <text>Heru Santoso Wahito Nugroho,1 Joel Rey Ugsang Acob,2 Wiwin Martiningsih3 1Poltekkes Kemenkes Surabaya, Surabaya, Indonesia; 2Faculty of Nursing, Visayas State University, Baybay, Philippines; 3Nursing Department, Poltekkes Kemenkes Malang, Malang, IndonesiaCorrespondence: Wiwin MartiningsihNursing Department, Poltekkes Kemenkes Malang, Jl. Ijen 77 C, Malang, IndonesiaEmail martini2271@gmail.com We have read the article &amp;ldquo;Healthcare Worker&amp;rsquo;s Mental Health and Their&amp;nbsp;Associated Predictors During the Epidemic Peak of COVID-19&amp;rdquo;. Based on the&amp;nbsp;results, the researchers concluded that healthcare worker&amp;rsquo;s stress, anxiety and&amp;nbsp;depression are influenced by social-support, working time, discrimination and&amp;nbsp;workplace violence; and not influenced by age, gender, working at designated&amp;nbsp;hospital, medical equipment, patient&amp;ndash;physician relations and household transmission-&amp;nbsp;related fears.1 &amp;nbsp; View the original paper by Yang and colleagues</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="85352">
                <text>2021</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="85353">
                <text>Anxiety, Stress, Depression, Health worker</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="85354">
                <text>Biotemas</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="85355">
                <text>Universidade Federal de Santa Catarina</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="85356">
                <text>Psychology, Industrial psychology</text>
              </elementText>
            </elementTextContainer>
          </element>
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  <item itemId="10239" public="1" featured="0">
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Some opportunities for immunotherapy in coronavirus infection</text>
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              <elementText elementTextId="85358">
                <text>Areg A. Totolian, V. S. Smirnov</text>
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                <text>Here we review means of immunomodulatory therapy for coronavirus infection caused by SARS-CoV-2 (COVID-19). It has been appreciated that highly limited arsenal of relatively effective means and methods of prevention and treatment of the COVID-19 pandemic is available. The goal of our study was to analyze some therapeutic approaches based on available publications for COVID-19 treatment viewed from acting via innate immunity system. Convalescent plasma serotherapy represents one of the means with verified therapeutic efficacy that was accompanied with decreased viral load and relief of the disease symptoms. The drawback of serotherapy results from limited number of potential plasma donors and profound variety in amount of SARS-CoV-2-specific antibodies found in donor plasma. Another approach to COVID-19 therapy is based on using monoclonal antibodies engineered to target specific virus antigenic determinants, most often surface spike antigen. Antibodies blocking such antigen are able to prevent virus entrance into target cells and development of overt infection. On the other hand, there are monoclonal antibodies abrogating production or binding of excessive amounts of pro-inflammatory cytokines, such as IL-6, TNFα, etc., some of which (tocilizumab) have been already tested in COVID-19 therapy, whereas the remaining preparations are being currently investigated and tested. A certain breakthrough in COVID-19 therapy was provided by the well-known drugs chloroquine and dihydrochloroquine, which have proven to be effective as antiviral, anti-inflammatory and immunomodulatory means. Finally, a new multicomponent immunomodulatory preparation Cytovir-3 has been proposed already passed clinical trials and recommended for use in prevention and treatment of influenza and SARS and might have found its own niche in preventing COVID-19, as SARS-CoV-2 also belongs to the group of acute respiratory viruses. Thus, the arsenal of means for COVID-19 prevention and treatment contains the drugs for immunomodulatory therapy and prevention of immune-related disorders developing in response to invasion pathogenic viruses and lowering a risk of possible damage. Hence, correct and scientifically justified use of such remedies will increase overall effectiveness of fight against the coronavirus pandemic.</text>
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                <text>2020</text>
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                <text>MERS-CoV, SARS-CoV, coronavirus, covid-19, chloroquine, monoclonal antibodies, Serotherapy, plasma of convalescents, dihydrochloroquine, cytovir-3</text>
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                <text>10.15789/2220-7619-SPO-1470</text>
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            <name>Source</name>
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                <text>Infekciâ i Immunitet</text>
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          <element elementId="45">
            <name>Publisher</name>
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                <text>Sankt-Peterburg : NIIÈM imeni Pastera</text>
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                <text>Infectious and parasitic diseases</text>
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