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              <name>Title</name>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Potential Therapeutic Targeting of Coronavirus Spike Glycoprotein Priming</text>
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                <text>Elisa Barile, Carlo Baggio, Luca Gambini, Sergey  A. Shiryaev, Alex  Y. Strongin and Maurizio Pellecchia</text>
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                <text>Processing of certain viral proteins and bacterial toxins by host serine proteases is a frequent and critical step in virulence. The coronavirus spike glycoprotein contains three (S1, S2, and S2′) cleavage sites that are processed by human host proteases. The exact nature of these cleavage sites, and their respective processing proteases, can determine whether the virus can cross species and the level of pathogenicity. Recent comparisons of the genomes of the highly pathogenic SARS-CoV2 and MERS-CoV, with less pathogenic strains (e.g., Bat-RaTG13, the bat homologue of SARS-CoV2) identified possible mutations in the receptor binding domain and in the S1 and S2′ cleavage sites of their spike glycoprotein. However, there remains some confusion on the relative roles of the possible serine proteases involved for priming. Using anthrax toxin as a model system, we show that in vivo inhibition of priming by pan-active serine protease inhibitors can be effective at suppressing toxicity. Hence, our studies should encourage further efforts in developing either pan-serine protease inhibitors or inhibitor cocktails to target SARS-CoV2 and potentially ward off future pandemics that could develop because of additional mutations in the S-protein priming sequence in coronaviruses.</text>
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                <text>2020</text>
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                <text>TMPRSS2, covid-19, SARS-CoV-2, furin, anthrax toxin, protecting antigen</text>
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            <name>Identifier</name>
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                <text>10.3390/molecules25102424</text>
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                <text>Biotemas</text>
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            <name>Publisher</name>
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                <text>Universidade Federal de Santa Catarina</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Organic chemistry</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Online Medical Education in Nepal: Barking a Wrong Tree</text>
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            <description>An entity primarily responsible for making the resource</description>
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                <text>Alok Atreya, Binu Nepal</text>
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            <description>An account of the resource</description>
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                <text>To combat the global pandemic of Covid-19, the Government of Nepal declared a country wide lockdown on 24 March, 2020. The lockdown affected all the institutions, medical schools being no exception.   To keep in pace with the academic calendar, most of the universities instructed their affiliated medical schools to start online classes for medical undergraduates. Kathmandu University which affiliates ten medical schools under its umbrella circulated a notice to start online classes. To facilitate this, the most important requisite is internet connection. A working device in the form of a laptop, desktop, or smartphone is needed to log in through the internet. After the lockdown, when all the medical schools closed, the students went home. We should not forget the fact that many students are from rural locality with no access to the internet at their home. The mobile internet data is costly and more data is consumed during video conferencing in online classes. The geographical remoteness further hinders the network coverage across the country.</text>
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              <elementText elementTextId="86544">
                <text>2020</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>covid-19, Nepal, online classes</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>10.22502/jlmc.v8i1.325</text>
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            <name>Source</name>
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              <elementText elementTextId="86547">
                <text>Journal of Lumbini Medical College</text>
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            <name>Publisher</name>
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                <text>Lumbini Medical College</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="86549">
                <text>Medicine (General)</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="86532">
                <text>Potential Benefits and Harms of Novel Antidiabetic Drugs During COVID-19 Crisis</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="86533">
                <text>Eusebio Chiefari, Antonio Brunetti, Maria Mirabelli, Luigi Puccio, Daniela  Patrizia Foti</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="86534">
                <text>Patients with diabetes have been reported to have enhanced susceptibility to severe or fatal COVID-19 infections, including a high risk of being admitted to intensive care units with respiratory failure and septic complications. Given the global prevalence of diabetes, affecting over 450 million people worldwide and still on the rise, the emerging COVID-19 crisis poses a serious threat to an extremely large vulnerable population. However, the broad heterogeneity and complexity of this dysmetabolic condition, with reference to etiologic mechanisms, degree of glycemic derangement and comorbid associations, along with the extensive sexual dimorphism in immune responses, can hamper any patient generalization. Even more relevant, and irrespective of glucose-lowering activities, DPP4 inhibitors and GLP1 receptor agonists may have a favorable impact on the modulation of viral entry and overproduction of inflammatory cytokines during COVID-19 infection, although current evidence is limited and not univocal. Conversely, SGLT2 inhibitors may increase the likelihood of COVID-19-related ketoacidosis decompensation among patients with severe insulin deficiency. Mindful of their widespread popularity in the management of diabetes, addressing potential benefits and harms of novel antidiabetic drugs to clinical prognosis at the time of a COVID-19 pandemic deserves careful consideration.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="86535">
                <text>2020</text>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="86536">
                <text>covid-19, diabetes, DPP-4 inhibitors, SGLT2 inhibitors, GLP-1 receptor agonists</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="86537">
                <text>10.3390/ijerph17103664</text>
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          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="86538">
                <text>Epidemiology and Health</text>
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          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="86539">
                <text>Korean Society of Epidemiology</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="86540">
                <text>Medicine</text>
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  </item>
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        <src>https://www.socictopen.socict.org/files/original/4874351c836364f79186539d8e42e045.pdf</src>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                <elementText elementTextId="1">
                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
                </elementText>
              </elementTextContainer>
            </element>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="86523">
                <text>The pulmonary sequalae in discharged patients with COVID-19: a short-term observational study</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="86524">
                <text>Dehan Liu, Feng Pan, Lin Li, Bo Liang, Lian Yang, Wanshu Zhang, Dandan Zheng, Jiazheng Wang</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>Abstract Background A cluster of patients with coronavirus disease 2019 (COVID-19) pneumonia were discharged from hospitals in Wuhan, China. We aimed to determine the cumulative percentage of complete radiological resolution at each time point, to explore the relevant affecting factors, and to describe the chest CT findings at different time points after hospital discharge. Methods Patients with COVID-19 pneumonia confirmed by RT-PCR who were discharged consecutively from the hospital between 5 February 2020 and 10 March 2020 and who underwent serial chest CT scans on schedule were enrolled. The radiological characteristics of all patients were collected and analysed. The total CT score was the sum of non-GGO involvement determined at discharge. Afterwards, all patients underwent chest CT scans during the 1st, 2nd, and 3rd weeks after discharge. Imaging features and distributions were analysed across different time points. Results A total of 149 patients who completed all CT scans were evaluated; there were 67 (45.0%) men and 82 (55.0%) women, with a median age of 43 years old (IQR 36–56). The cumulative percentage of complete radiological resolution was 8.1% (12 patients), 41.6% (62), 50.3% (75), and 53.0% (79) at discharge and during the 1st, 2nd, and 3rd weeks after discharge, respectively. Patients ≤44 years old showed a significantly higher cumulative percentage of complete radiological resolution than patients &gt; 44 years old at the 3-week follow-up. The predominant patterns of abnormalities observed at discharge were ground-glass opacity (GGO) (125 [83.9%]), fibrous stripe (81 [54.4%]), and thickening of the adjacent pleura (33 [22.1%]). The positive count of GGO, fibrous stripe and thickening of the adjacent pleura gradually decreased, while GGO and fibrous stripe showed obvious resolution during the first week and the third week after discharge, respectively. “Tinted” sign and bronchovascular bundle distortion as two special features were discovered during the evolution. Conclusion Lung lesions in COVID-19 pneumonia patients can be absorbed completely during short-term follow-up with no sequelae. Two weeks after discharge might be the optimal time point for early radiological estimation.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="86526">
                <text>2020</text>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="86527">
                <text>covid-19, follow-up, ct, discharge, GGO, sequalae</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="86528">
                <text>10.1186/s12931-020-01385-1</text>
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            </elementTextContainer>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="86529">
                <text>Biotemas</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="86530">
                <text>Universidade Federal de Santa Catarina</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="86531">
                <text>Diseases of the respiratory system</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>An Overview of Signal Processing Techniques for Remote Health Monitoring Using Impulse Radio UWB Transceiver</text>
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                <text>Faheem Khan, Asim Ghaffar, Naeem Khan, Sung  Ho Cho</text>
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                <text>Non-invasive remote health monitoring plays a vital role in epidemiological situations such as SARS outbreak (2003), MERS (2015) and the recently ongoing outbreak of COVID-19 because it is extremely risky to get close to the patient due to the spread of contagious infections. Non-invasive monitoring is also extremely necessary in situations where it is difficult to use complicated wired connections, such as ECG monitoring for infants, burn victims or during rescue missions when people are buried during building collapses/earthquakes. Due to the unique characteristics such as higher penetration capabilities, extremely precise ranging, low power requirement, low cost, simple hardware and robustness to multipath interferences, Impulse Radio Ultra Wideband (IR-UWB) technology is appropriate for non-invasive medical applications. IR-UWB sensors detect the macro as well as micro movement inside the human body due to its fine range resolution. The two vital signs, i.e., respiration rate and heart rate, can be measured by IR-UWB radar by measuring the change in the magnitude of signal due to displacement caused by human lungs, heart during respiration and heart beating. This paper reviews recent advances in IR- UWB radar sensor design for healthcare, such as vital signs measurements of a stationary human, vitals of a non-stationary human, vital signs of people in a vehicle, through the wall vitals measurement, neonate’s health monitoring, fall detection, sleep monitoring and medical imaging. Although we have covered many topics related to health monitoring using IR-UWB, this paper is mainly focused on signal processing techniques for measurement of vital signs, i.e., respiration and heart rate monitoring.</text>
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                <text>algorithm, Vital signs, respiration rate, heart rate, motion detection, IR-UWB radar</text>
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                <text>10.3390/s20092479</text>
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                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Chemical technology</text>
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              <name>Title</name>
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                  <text>Dominio científico: Coronavirus</text>
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          <element elementId="50">
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                <text>Biopolitics and legal issues of emergency situations in the context of coronavirus pandemic</text>
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                <text>Denisenko Vladislav, Trikoz Elena</text>
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                <text>It is difficult to overestimate the importance of biopolitical issues at the present time. The modern social state and the developing biolaw regulate a lot of private and public legal relations, especially the sensitive sphere of somatic and reproductive human rights, and the biological status of citizens. The most important aspect of national legal regulation, such as the ratio of law and morality, international bio-standards, is being updated, and the status of bioethics and biolaw is being raised. The development of modern genetic engineering and biotechnologies raises the question of the legal boundaries of biopolitics. It has been found that national governments often expand biopolitical impact in situations of emergency and new biohazards, in particular, the COVID-19 pandemic. The paper is prepared using doctrinal-legal and comparative-synchronous analysis of legal measures applied by different countries in the field of biopolitics. The research is based on extensive scientific and regulatory material. As a result, it was concluded that at the current stage of countering the pandemic, many countries restrict the biological rights of citizens and activate genetic technologies. The Russian and foreign experience of biopolitics in the state of emergency wasstudied.</text>
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                <text>2020</text>
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                <text>10.1051/e3sconf/202017514013</text>
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                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Environmental sciences</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Medical and Paramedical Care of Patients With Cerebellar Ataxia During the COVID-19 Outbreak: Seven Practical Recommendations of the COVID 19 Cerebellum Task Force</text>
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                <text>Bing-Wen Soong, Bing-Wen Soong, Elan D. Louis, Mario Manto, Nicolas Dupre, Marios Hadjivassiliou, Hiroshi Mitoma, Marco Molinari, Aasef G. Shaikh, Bing-Wen Soong, Michael Strupp, Frank Van Overwalle, Jeremy D. Schmahmann</text>
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                <text>The severe acute respiratory syndrome coronavirus 2 (SARS-CoV2), the cause of the current pandemic coronavirus disease 2019 (COVID-19), primarily targets the respiratory system. Some patients also experience neurological signs and symptoms ranging from anosmia, ageusia, headache, nausea, and vomiting to confusion, encephalitis, and stroke. Approximately 36% of those with severe COVID-19 experience neurological complications. The virus may enter the central nervous system through the olfactory nerve in the nasal cavity and damage neurons in the brainstem nuclei involved in the regulation of respiration. Patients with cerebellar ataxia (CA) are particularly vulnerable to severe outcome if they contract COVID-19 because of the complexity of their disease, the presence of comorbidities, and their use of immunosuppressive therapies. Most CA patients burdened by progressive neurologic deficits have substantially impaired mobility and other essential functions, for which they rely heavily on ambulatory services, including rehabilitation and psychosocial care. Cessation of these interventions because of isolation restrictions places the CA patient population at risk of further deterioration. This international panel of ataxia experts provides recommendations for neurologists caring for patients with CA, emphasizing a pro-active approach designed to maintain their autonomy and well-being: continue long-term medications, promote rehabilitation efforts, utilize the technology of virtual visits for regular contact with healthcare providers, and pay attention to emotional and psychosocial health. Neurologists should play an active role in decision-making in those CA cases requiring escalation to intensive care and resuscitation. Multi-disciplinary collaboration between care teams is always important, and never more so than in the context of the current pandemic.</text>
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                <text>2020</text>
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                <text>covid-19, SARS-CoV-2, therapies, Ataxia, Cerebellum</text>
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              <elementText elementTextId="86502">
                <text>10.3389/fneur.2020.00516</text>
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                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Neurology. Diseases of the nervous system</text>
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              <name>Title</name>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Impact of the COVID-19 pandemic on court proceedings in Lithuania</text>
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                <text>Vėbraitė Vigita</text>
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                <text>The pandemic of coronavirus COVID-19 has impacted almost all areas of life throughout the word. Justice system in Lithuania was no exception. The effects of the pandemichave been felt till now (the article was finished at the end of August), even if the lockdownwas ended on the 16th of June and until now country remains under the conditions of anemergency situation. This article will describe the most important effects of the pandemicto the court proceedings in Lithuania and what lessons could be learned from this situation.</text>
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                <text>2020</text>
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                <text>covid-19, civil justice, court proceedings, ‘hybrid’ hearing, online justice</text>
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                <text>10.33327/AJEE-18-3.2-3-n000032</text>
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                <text>Access to Justice in Eastern Europe</text>
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                <text>VD Dakor</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Law of Europe</text>
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  <item itemId="10366" public="1" featured="0">
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                  <text>Dominio científico: Coronavirus</text>
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                <text>COVID-19 Deaths: Are We Sure It Is Pneumonia? Please, Autopsy, Autopsy, Autopsy!</text>
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                <text>Giovanni Li Volti, Cristoforo Pomara, Francesco Cappello</text>
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                <text>The current outbreak of COVID-19 severe respiratory disease, which started in Wuhan, China, is an ongoing challenge, and a major threat to public health that requires surveillance, prompt diagnosis, and research efforts to understand this emergent pathogen and to develop an effective response. Due to the scientific community’s efforts, there is an increasing body of published studies describing the virus’ biology, its transmission and diagnosis, its clinical features, its radiological findings, and the development of candidate therapeutics and vaccines. Despite the decline in postmortem examination rate, autopsy remains the gold standard to determine why and how death happens. Defining the pathophysiology of death is not only limited to forensic considerations; it may also provide useful clinical and epidemiologic insights. Selective approaches to postmortem diagnosis, such as limited postmortem sampling over full autopsy, can also be useful in the control of disease outbreaks and provide valuable knowledge for managing appropriate control measures. In this scenario, we strongly recommend performing full autopsies on patients who died with suspected or confirmed COVID-19 infection, particularly in the presence of several comorbidities. Only by working with a complete set of histological samples obtained through autopsy can one ascertain the exact cause(s) of death, optimize clinical management, and assist clinicians in pointing out a timely and effective treatment to reduce mortality. Death can teach us not only about the disease, it might also help with its prevention and, above all, treatment.</text>
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                <text>2020</text>
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                <text>infectious diseases, covid-19, Diagnosis, autopsy</text>
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              <elementText elementTextId="86484">
                <text>10.3390/jcm9051259</text>
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              <elementText elementTextId="86485">
                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Medicine</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>DOES THE PRUNING ON THE REFERENCE INTEREST RATE BY BANK INDONESIA INFLUENCE INTEREST RATE SENSITIVITY TOWARDS BANKING NET INTEREST MARGIN DURING EARLY PERIOD IN FACING COVID-19 IN INDONESIA?</text>
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                <text>M Rizki Nurhuda, Muhammad Rozali, Latifa Rakhmatillah, Hendri Hermawan Adinugraha</text>
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                <text>On March 2, 2020, Indonesian citizens tested positive for Coronavirus Disease (COVID-19) for the first time, making Indonesia the start of facing various problems in the health and economic sectors. All ministries or agencies are mitigating it using the extraordinary policy which adapts to the rapid growth in the number of positive patients for COVID-19 in Indonesia, including Bank Indonesia by gradually lowering the Reference Interest Rate, causing changes in the Interest Rates Sensitivity (Asset or Liability) Banking. It should be noted that interest income contributes greatly to the income of a bank. Based on this, this study aims to test whether the Bank Indonesia policy affects the Banking Net Interest Margin during the first four months since the detection of the first positive case of COVID-19 in Indonesia. By using Multiple Linear Regression Analysis, this paper concludes that changes in the reference interest rate made by Bank Indonesia in the face of the impact of the COVID-19 Pandemic strongly affects the Rate of Fixed / Sensitive Assets and Liabilities to the ratio of Net Interest Margin (NIM). Where the correlation is strong. This shows that changes in the Reference interest rate carried out by Bank Indonesia must be carried out gradually and carefully so as not to cause major changes to banking performance during the face of the COVID-19) Pandemic in Indonesia.</text>
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                <text>covid-19, net interest margin, interest rate sensitivity, bank of indonesia</text>
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                <text>Biotemas</text>
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                <text>Universidade Federal de Santa Catarina</text>
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                <text>Journalism. The periodical press, etc.</text>
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