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                  <text>Agricultura sostenible</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Agricultura sostenible</text>
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                <text>Hyphomycetes from soil of an area affected by copper mining activities in the State of Bahia, Brazil Hyphomycetes de solo de uma área de mineração de cobre no Estado da Bahia, Brasil</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="193482">
                <text>Isabella P.M. Wanderley Costa, Maria Auxiliadora Q. Cavalcanti, Maria José S. Fernandes, Débora M.M. Lima</text>
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            <description>An account of the resource</description>
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                <text>With the aim of observing the impact produced by copper-mining activities on soil fungi, samples were collected from an area at the Caraíba Mining, in the State of Bahia, Brazil. This area was divided in six sub-areas: one had native vegetation and was used as control, while the others varied according to degrees of impact. The samples, collected during the dry and the rainy seasons, were submitted to serial dilutions and placed on Petri dishes with Sabouraud medium plus antibiotic. Sixty five species and 16 genera of Hyphomycetes were identified: Acremonium, Acrophialophora, Aspergillus, Cladosporium, Chrysosporium, Curvularia, Fusarium, Humicola, Malbranchea, Myrothecium, Paecilomyces, Penicillium, Scolecobasidium, Staphylotrichum, Stilbella and Trichoderma.Acrophialophora levis, Crhysosporium merdarium, Curvularia verruculosa, Malbranchea chrysosporoidea, Penicillium adametzii, Staphylotrichum coccosporum and Stilbella sebacea were isolated for the first time in Brazil.Com o objetivo de observar o impacto produzido pelas atividades da mineração de cobre em fungos do solo, amostras foram coletadas de uma área da Mineração Caraíba no Estado da Bahia, Brasil. Esta área foi dividida em seis sub-áreas: uma com vegetação nativa, usada como controle enquanto as outras variavam de acordo com os graus de impacto. As amostras, coletadas durante os períodos de estiagem e chuvoso, foram submetidas a diluições sucessivas e colocadas em placas de Petri contendo meio Sabouraud acrescido de antibiótico. Sessenta e cinco espécies e 16 gêneros de Hyphomycetes foram identificados: Acremonium, Acrophialophora, Aspergillus, Cladosporium, Chrysosporium, Curvularia, Fusarium, Humicola, Malbranchea, Myrothecium, Paecilomyces, Penicillium, Scolecobasidium, Staphilotricum, Stilbella e Trichoderma.Acrophialophora levis, Chrysosporium merdarium, Curvularia verruculosa, Malbranchea chrysosporoidea, Penicillium adametzii, Staphylotrichum coccosporum e Stilbella sebacea foram isoladas pela primeira vez no Brasil.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="193484">
                <text>2006</text>
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            </elementTextContainer>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="193485">
                <text>ecology, ecología, fungos de solo, impacted area, micologia, mycology, soil fungi, área impactada</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="193486">
                <text>10.1590/S1517-83822006000300017</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="193487">
                <text>Brazilian Journal of Microbiology</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>Sociedade Brasileira de Microbiologia</text>
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                <text>Microbiology</text>
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            <description>A related resource</description>
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                <text>&lt;a href="http://www.scielo.br/scielo.php?script=sci_arttext&amp;amp;pid=S1517-83822006000300017" target="_blank" rel="noreferrer noopener"&gt;http://www.scielo.br/scielo.php?script=sci_arttext&amp;amp;pid=S1517-83822006000300017&lt;/a&gt;</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Hypoalbuminemia as Surrogate and Culprit of Infections</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="79708">
                <text>Christian  J. Wiedermann</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="79709">
                <text>Hypoalbuminemia is associated with the acquisition and severity of infectious diseases, and intact innate and adaptive immune responses depend on albumin. Albumin oxidation and breakdown affect interactions with bioactive lipid mediators that play important roles in antimicrobial defense and repair. There is bio-mechanistic plausibility for a causal link between hypoalbuminemia and increased risks of primary and secondary infections. Serum albumin levels have prognostic value for complications in viral, bacterial and fungal infections, and for infectious complications of non-infective chronic conditions. Hypoalbuminemia predicts the development of healthcare-associated infections, particularly with Clostridium difficile. In coronavirus disease 2019, hypoalbuminemia correlates with viral load and degree of acute lung injury and organ dysfunction. Non-oncotic properties of albumin affect the pharmacokinetics and pharmacodynamics of antimicrobials. Low serum albumin is associated with inadequate antimicrobial treatment. Infusion of human albumin solution (HAS) supplements endogenous albumin in patients with cirrhosis of the liver and effectively supported antimicrobial therapy in randomized controlled trials (RCTs). Evidence of the beneficial effects of HAS on infections in hypoalbuminemic patients without cirrhosis is largely observational. Prospective RCTs are underway and, if hypotheses are confirmed, could lead to changes in clinical practice for the management of hypoalbuminemic patients with infections or at risk of infectious complications.</text>
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              <elementText elementTextId="79710">
                <text>2021</text>
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              <elementText elementTextId="79711">
                <text>infections, Community-acquired pneumonia, innate immunity, Hypoalbuminemia, albumins/pharmacology, bioactive lipid mediators</text>
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              <elementText elementTextId="79712">
                <text>10.3390/ijms22094496</text>
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            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="79713">
                <text>Epidemiology and Health</text>
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          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="79714">
                <text>Korean Society of Epidemiology</text>
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            </elementTextContainer>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="79715">
                <text>Biology (General), Chemistry</text>
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                  <text>Coronavirus</text>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
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              <elementText elementTextId="71705">
                <text>Hypocalcemia and hypoalbuminemia during COVID-19 infection: Opportunities for therapeutic intervention.</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="71706">
                <text>Biswajit Khatua, Bara El-Kurdi, Vijay P Singh</text>
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            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2020</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="71708">
                <text>10.1016/j.jiph.2020.09.019</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="71709">
                <text>Journal of infection and public health</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Hypocalcemia: the quest for the cause of a major biochemical feature of COVID-19.</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="59974">
                <text>Luigi di Filippo, Anna Maria Formenti, Andrea Giustina</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2020</text>
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            <name>Identifier</name>
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              <elementText elementTextId="59976">
                <text>10.1007/s12020-020-02525-9</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="59977">
                <text>Endocrine</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                <elementText elementTextId="1">
                  <text>Coronavirus</text>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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              </elementTextContainer>
            </element>
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    </collection>
    <itemType itemTypeId="1">
      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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    <elementSetContainer>
      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="9637">
                <text>Hypomethylated domain-enriched DNA motifs prepattern the accessible nucleosome organization in teleosts</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="9638">
                <text>Ryohei Nakamura, Ayako Uno, Masahiko Kumagai, Shinichi Morishita, Hiroyuki Takeda</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="9639">
                <text>Abstract Background Gene promoters in vertebrate genomes show distinct chromatin features such as stably positioned nucleosome array and DNA hypomethylation. The nucleosomes are known to have certain sequence preferences, and the prediction of nucleosome positioning from DNA sequence has been successful in some organisms such as yeast. However, at gene promoters where nucleosomes are much more stably positioned than in other regions, the sequence-based model has failed to work well, and sequence-independent mechanisms have been proposed. Results Using DNase I-seq in medaka embryos, we demonstrated that hypomethylated domains (HMDs) specifically possess accessible nucleosome organization with longer linkers, and we reassessed the DNA sequence preference for nucleosome positioning in these specific regions. Remarkably, we found with a supervised machine learning algorithm, k-mer SVM, that nucleosome positioning in HMDs is accurately predictable from DNA sequence alone. Specific short sequences (6-mers) that contribute to the prediction are specifically enriched in HMDs and distribute periodically with approximately 200-bp intervals which prepattern the position of accessible linkers. Surprisingly, the sequence preference of the nucleosome and linker in HMDs is opposite from that reported previously. Furthermore, the periodicity of specific motifs at hypomethylated promoters was conserved in zebrafish. Conclusion This study reveals strong link between nucleosome positioning and DNA sequence at vertebrate promoters, and we propose hypomethylated DNA-specific regulation of nucleosome positioning.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="9640">
                <text>2017</text>
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            </elementTextContainer>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="9641">
                <text>nucleosome positioning, DNA methylation, DNA sequence, vertebrate</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="9642">
                <text>DOI: 10.1186/s13072-017-0152-2</text>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="9643">
                <text>Epigenetics &amp; Chromatin</text>
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            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="9644">
                <text>BMC</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="9645">
                <text>Genetics</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="44">
            <name>Language</name>
            <description>A language of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="9646">
                <text>EN</text>
              </elementText>
            </elementTextContainer>
          </element>
        </elementContainer>
      </elementSet>
    </elementSetContainer>
  </item>
</itemContainer>
