1033 10 20655 https://www.socictopen.socict.org/files/original/419630d5f6246370da0c8086a7222f8b.pdf b8222458ea32e0601816f9cf0ca73b90 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The Costs of the COVID-19 on Subjective Well-Being: An Analysis of the Outbreak in Spain Creator An entity primarily responsible for making the resource Ana Blasco-Belled, Claudia Tejada-Gallardo, Cristina Torrelles-Nadal, Carles Alsinet Description An account of the resource The COVID-19 outbreak entailed radical shifts to individuals’ daily habits that challenged their subjective well-being (SWB). Knowledge about the impact of COVID-19 on SWB is paramount for developing public policies to tackle mental health during health emergency periods. Decreases in life satisfaction are likely not only due to exposure to daily negative emotions but also due to hopelessness, fear, and avoidance of social interactions. We examined in a sample of 541 Spanish adults (1) reactions to the COVID-19 outbreak and (2) the mediating role of these reactions in the associations of hope and social phobia with life satisfaction through different levels of positive and negative affect. A moderated mediation analysis showed that the conditional indirect effect of hope and social anxiety on life satisfaction through information depended on the participants’ having high positive affect and low negative affect. Affect seems to be a mechanism that modulates the influence of individuals’ perception about COVID-19 on their life satisfaction. Those with high positive affect might see the “general picture” and search for adequate information as they avoid focusing on the problem and on specific information that precludes preventive behaviors. Having a positive affect might help individuals to adopt information-processing strategies during the COVID-19 outbreak that will improve their life satisfaction. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource coronavirus, mental health, covid-19, subjective wellbeing, Hope, social phobia Identifier An unambiguous reference to the resource within a given context 10.3390/su12156243 Source A related resource from which the described resource is derived Biotemas Publisher An entity responsible for making the resource available Universidade Federal de Santa Catarina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Environmental effects of industries and plants, Renewable energy sources, Environmental sciences https://www.socictopen.socict.org/files/original/e8f4c56d37718100f9d72cfeb67764ab.pdf c795ea3ea78173b9ca0954a6ae1e22a5 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Blockchain and Artificial Intelligence Technology for Novel Coronavirus Disease 2019 Self-Testing Creator An entity primarily responsible for making the resource Tivani P. Mashamba-Thompson, Ellen Debra Crayton Description An account of the resource The novel coronavirus disease 2019 (COVID-19) is rapidly spreading with a rising death toll and transmission rate reported in high income countries rather than in low income countries. The overburdened healthcare systems and poor disease surveillance systems in resource-limited settings may struggle to cope with this COVID-19 outbreak and this calls for a tailored strategic response for these settings. Here, we recommend a low cost blockchain and artificial intelligence-coupled self-testing and tracking systems for COVID-19 and other emerging infectious diseases. Prompt deployment and appropriate implementation of the proposed system have the potential to curb the transmissions of COVID-19 and the related mortalities, particularly in settings with poor access to laboratory infrastructure. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource artificial intelligence, blockchain, Self-testing, novel coronavirus disease-19 Identifier An unambiguous reference to the resource within a given context 10.3390/diagnostics10040198 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine (General) https://www.socictopen.socict.org/files/original/379a9eb366193c562dece7b9dc69f089.pdf c3c4d72c58079dab3e861303d071271b Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Convalescent plasma therapy in COVID-19 patients, in the Province of Buenos Aires Creator An entity primarily responsible for making the resource Soledad E. González, Lorena Regairaz, Noelia S. Ferrando, Veronica V. González Martínez, Martín R. Salazar, Elisa Estenssoro Description An account of the resource This is a preliminary, multicenter, retrospective cohort study, including 272 consecutive patients with COVID-19 admitted to hospitals in Buenos Aires Province, between May 15th and July 1st, 2020, included in an expanded access program to convalescent plasma. Our objectives were to analyze mortality and its independent risk factors, and to assess the occurrence of a favorable evolution, defined as hospital discharge, or stay at the ward, or transfer from ICU to ward. Patients were stratified int o 4 subgroups: admission to the ward with pneumonia and/or oxygen requirement (WARD; n = 100); ICU admission (ICU; n = 87); ICU admission with requirement of mechanical ventilation (ICU-MV; n = 56), and ICU-MV plus septic shock (ICU-MV-SS; N = 29). Mortality at 28 days was 26.1% for the entire group, 14.0% for WARD group, 18.4% for ICU, 44.6% for ICU-MV, and 55.2% for ICU-MV-SS. Mean survival time (days) was 25.6 ± 0.6 (WARD); 25.3 ± 0.7 (ICU); 20.8 ± 1.2 (ICU-MV) and 18.2 ± 1.8 (ICU-MV-SS). Independent predictors of mortality were MV, septic shock and weight. A favorable evolution occurred in 81.4% of WARD patients; in 70.9% of ICU; in 39.6% of ICU-MV and in 27.6% of ICU-MV-SS patients. Severity of illness on admission, age, weight and heart rate were independently associated with evolution. No major adverse effects were recorded. The lack of a control group precluded the estimation of efficacy. However, our 26% mortality rate was higher than that of the treatment arm of clinical trials comparing plasma with usual treatment, which might be ascribed to higher proportion of patients with MV and septic shock in our cohort. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, convalescent plasma, expanded access program Source A related resource from which the described resource is derived Medicina (Buenos Aires) Publisher An entity responsible for making the resource available Fundación Revista Medicina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine, Infectious and parasitic diseases, Immunologic diseases. Allergy https://www.socictopen.socict.org/files/original/28664a9d0c4c2099188efdcb33a4b14e.pdf 43750d8a9ffa5e37a5ee2eb9230a7e12 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource COVID-19 and the UN Sustainable Development Goals: Threat to Solidarity or an Opportunity? Creator An entity primarily responsible for making the resource Walter Leal Filho, Luciana Londero Brandli, Amanda Lange Salvia, Lez Rayman-Bacchus, Johannes Platje Description An account of the resource COVID-19, as a pandemic, is impacting institutions around the world. Its scope and economic dimensions also mean that it poses a major threat towards achieving the UN Sustainable Development Goals (SDGs). This article discusses how the coronavirus pandemic may influence the SDGs and could affect their implementation. The methods used entail an analysis of the literature, observations and an assessment of current world trends. The results obtained point out that, while COVID-19 has become a priority to many health systems in developing nations, they still need to attend to many other existing diseases such as malaria, yellow fever and others. Further, the study shows that strong concerns in dealing with COVID-19 are disrupting other disease prevention programs. As a result, problems such as mental health are also likely to be overlooked, since the isolation of social distancing may mask or lead to an increase in the percentage of suffers. The paper suggests that, due to its wide scope and areas of influence, COVID-19 may also jeopardize the process of the implementation of the SDGs. It sends a cautious warning about the need to continue to put an emphasis on the implementation of the SDGs, so that the progress achieved to date is not endangered. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource un sustainable development goals, SDGs implementation, COVID-19 pandemic economic impact Identifier An unambiguous reference to the resource within a given context 10.3390/su12135343 Source A related resource from which the described resource is derived Biotemas Publisher An entity responsible for making the resource available Universidade Federal de Santa Catarina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Environmental effects of industries and plants, Renewable energy sources, Environmental sciences https://www.socictopen.socict.org/files/original/06c9ac74b77baf889f93b1333c59f4ce.pdf 988fce2434615ab29500f21113b7dc93 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The Impact of Isolation Due to COVID-19 on Physical Activity Levels in Adult Students Creator An entity primarily responsible for making the resource Anna Rutkowska, Katarzyna Kacperak, Sebastian Rutkowski, Luisa Cacciante, Pawel Kiper, Jan Szczegielniak Description An account of the resource The lockdown with a prohibition of free mobility introduced in many countries has affected restrictions in physical activity (PA). The purpose of the study was to compare PA during restrictions and the “unfreezing” stage. The study group consisted of 89 healthy adult students. To assess the level of PA, a long version of the International Physical Activity Questionnaire (IPAQ) was used. The first evaluation was carried out in the period from 16 to 20 April 2020 at the time of the lockdown and the second in the period from 11 to 14 May 2020 during the so-called “unfreezing”. The average total PA rate during the first measurement was 8640 metabolic equivalent (MET)-min/week and in the second, 10,560 MET-min/week. The analysis of total energy expenditure showed a statistically significant difference (p < 0.029). The establishment of “unfreezing” laws for sport and recreation and the reduction of restrictions have significantly contributed to an increase in the overall level of PA. Based on our outcomes, we recommend students follow the scientific guidelines for undertaking PA (i.e., WHO) during the pandemic in order to maintain an appropriate pro-healthy dose of exercise. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource covid-19, physical activity, energy expenditure, International Physical Activity Questionnaire (IPAQ) Identifier An unambiguous reference to the resource within a given context 10.3390/su13020446 Source A related resource from which the described resource is derived Biotemas Publisher An entity responsible for making the resource available Universidade Federal de Santa Catarina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Environmental effects of industries and plants, Renewable energy sources, Environmental sciences https://www.socictopen.socict.org/files/original/52f324eccb84acc75e497776caa8bdb2.pdf d7e93a8d025850bb3f1ca03a7374a3bf Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Social Distancing among Medical Students during the 2019 Coronavirus Disease Pandemic in China: Disease Awareness, Anxiety Disorder, Depression, and Behavioral Activities Creator An entity primarily responsible for making the resource Huidi Xiao, Wen Shu, Menglong Li, Ziang Li, Fangbiao Tao, Xiaoyan Wu, Yizhen Yu, Heng Meng, Sten H. Vermund, Yifei Hu Description An account of the resource Background: During the coronavirus disease (COVID-19) pandemic, harsh social distancing measures were taken in China to contain viral spread. We examined their impact on the lives of medical students. Methods: A nation-wide cross-sectional survey of college students was conducted from 4–12 February 2020. We enrolled medical students studying public health in Beijing and Wuhan to assess their COVID-19 awareness and to evaluate their mental health status/behaviors using a self-administered questionnaire. We used the Patient Generalized Anxiety Disorder-7 and Health Questionnaire-9 to measure anxiety disorders and depression. We used multivariable logistic regression and path analysis to assess the associations between covariates and anxiety disorder/depression. Results: Of 933 students, 898 (96.2%) reported wearing masks frequently when going out, 723 (77.5%) reported daily handwashing with soap, 676 (72.5%) washed hands immediately after arriving home, and 914 (98.0%) reported staying home as much as possible. Prevalence of anxiety disorder was 17.1% and depression was 25.3%. Multivariable logistic regression showed anxiety to be associated with graduate student status (odds ratio (aOR) = 2.0; 95% confidence interval (CI): 1.2–3.5), negative thoughts or actions (aOR = 1.6; 95% CI: 1.4–1.7), and feeling depressed (aOR = 6.8; 95% CI: 4.0–11.7). Beijing students were significantly less likely to have anxiety than those in the Wuhan epicenter (aOR = 0.9; 95% CI: 0.8–1.0), but depression did not differ. Depression was associated with female students (aOR = 2.0; 95% CI: 1.2–3.3), negative thoughts or actions (aOR = 1.7; 95% CI: 1.5–1.9), and anxiety disorder (aOR = 5.8; 95% CI: 3.4–9.9). Path analysis validated these same predictors. Conclusions: Despite medical students’ knowledge of disease control and prevention, their lives were greatly affected by social distancing, especially in the Wuhan epicenter. Even well-informed students needed psychological support during these extraordinarily stressful times. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, medical students, Depression, social distancing, anxiety disorder, personal protective measures Identifier An unambiguous reference to the resource within a given context 10.3390/ijerph17145047 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/74391d97e54d13c800cd04044fdb73e1.pdf dfa71ea08ddd6cadce0e48e24528fe5e Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Phosphate Derivatives of 3-Carboxyacylbetulin: SynThesis, In Vitro Anti-HIV and Molecular Docking Study Creator An entity primarily responsible for making the resource Elwira Chrobak, Krzysztof Marciniec, Aleksandra Dąbrowska, Paweł Pęcak, Ewa Bębenek, Monika Kadela-Tomanek, Stanisław Boryczka Description An account of the resource Lupane-type pentacyclic triterpenes such as betulin and betulinic acid play an important role in the search for new therapies that would be effective in controlling viral infections. The aim of this study was the synthesis and evaluation of in vitro anti-HIV-1 activity for phosphate derivatives of 3-carboxyacylbetulin 3–5 as well as an in silico study of new compounds as potential ligands of the C-terminal domain of the HIV-1 capsid–spacer peptide 1 (CA-CTD-SP1) as a molecular target of HIV-1 maturation inhibitors. In vitro studies showed that 28-diethoxyphosphoryl-3-O-(3′,3′-dimethylsuccinyl)betulin (compound 3), the phosphate analog of bevirimat (betulinic acid derivative, HIV-1 maturation inhibitor), has IC50 (half maximal inhibitory concentration) equal to 0.02 μM. Compound 3 inhibits viral replication at a level comparable to bevirimat and is also more selective (selectivity indices = 1250 and 967, respectively). Molecular docking was used to examine the probable interaction between the phosphate derivatives of 3-carboxyacylbetulin and C-terminal domain (CTD) of the HIV-1 capsid (CA)–spacer peptide 1 (SP1) fragment of Gag protein, designated as CTD-SP1. Compared with interactions between bevirimat (BVM) and the protein, an increased number of strong interactions between ligand 3 and the protein, generated by the phosphate group, were observed. These compounds might have the potential to also inhibit SARS-CoV2 proteins, in as far as the intrinsically imprecise docking scores suggest. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource SARS-CoV-2, triterpenes, anti HIV, Bevirimat Identifier An unambiguous reference to the resource within a given context 10.3390/biom10081148 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology https://www.socictopen.socict.org/files/original/ac9c6cff5620cc7840d8d475624096ba.pdf eb2a7fd4c9a5f6bca74df2d25e8d4979 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Changes in Tongue Kissing in Hook-Ups after COVID-19 Creator An entity primarily responsible for making the resource Laura Ruiz-Eugenio, Elisabeth Torras-Gómez, Garazi López de Aguileta-Jaussi, Nerea Gutiérrez-Fernández Description An account of the resource A growing body of social and behavioral sciences studies are providing evidence on how COVID-19 is influencing changes in society and among individuals. A few of those studies focus on how it is affecting behavioral and habit changes in stable couples. Yet its influence on changes in hook-ups remains understudied. To contribute to filling this gap, this exploratory study analyzes changes related to tongue kissing in hook-ups promoted by increased awareness of tongue kissing certain people as a potential source of transmission. Through pre- and post-test questionnaires given to 20 girls (18–30 years old), potential changes in the memories of past tongue-kissing hook-ups and in intentions and perceptions towards future ones can be observed among 12 participants. The implications of these findings suggest not only how the new normal might affect tongue kissing in hook-ups among these girls but also how these girls might freely decide with whom to engage in sexual-affective relationships in the future. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Prevention, covid-19, New normal, hookups, tongue kissing Identifier An unambiguous reference to the resource within a given context 10.3390/su12166309 Source A related resource from which the described resource is derived Biotemas Publisher An entity responsible for making the resource available Universidade Federal de Santa Catarina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Environmental effects of industries and plants, Renewable energy sources, Environmental sciences https://www.socictopen.socict.org/files/original/c6625a6c8d56415b6c3421d380d187d1.pdf 31e28b91b53d73dca878667b5cb313dc Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Winter Is Coming: A Southern Hemisphere Perspective of the Environmental Drivers of SARS-CoV-2 and the Potential Seasonality of COVID-19 Creator An entity primarily responsible for making the resource Robert J. Scholes, Albertus J. Smit, Jennifer M. Fitchett, Francois A. Engelbrecht, Godfrey Dzhivhuho, Neville A. Sweijd Description An account of the resource SARS-CoV-2 virus infections in humans were first reported in December 2019, the boreal winter. The resulting COVID-19 pandemic was declared by the WHO in March 2020. By July 2020, COVID-19 was present in 213 countries and territories, with over 12 million confirmed cases and over half a million attributed deaths. Knowledge of other viral respiratory diseases suggests that the transmission of SARS-CoV-2 could be modulated by seasonally varying environmental factors such as temperature and humidity. Many studies on the environmental sensitivity of COVID-19 are appearing online, and some have been published in peer-reviewed journals. Initially, these studies raised the hypothesis that climatic conditions would subdue the viral transmission rate in places entering the boreal summer, and that southern hemisphere countries would experience enhanced disease spread. For the latter, the COVID-19 peak would coincide with the peak of the influenza season, increasing misdiagnosis and placing an additional burden on health systems. In this review, we assess the evidence that environmental drivers are a significant factor in the trajectory of the COVID-19 pandemic, globally and regionally. We critically assessed 42 peer-reviewed and 80 preprint publications that met qualifying criteria. Since the disease has been prevalent for only half a year in the northern, and one-quarter of a year in the southern hemisphere, datasets capturing a full seasonal cycle in one locality are not yet available. Analyses based on space-for-time substitutions, i.e., using data from climatically distinct locations as a surrogate for seasonal progression, have been inconclusive. The reported studies present a strong northern bias. Socio-economic conditions peculiar to the ‘Global South’ have been omitted as confounding variables, thereby weakening evidence of environmental signals. We explore why research to date has failed to show convincing evidence for environmental modulation of COVID-19, and discuss directions for future research. We conclude that the evidence thus far suggests a weak modulation effect, currently overwhelmed by the scale and rate of the spread of COVID-19. Seasonally modulated transmission, if it exists, will be more evident in 2021 and subsequent years. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, SARS-CoV-2, temperature, seasonality, humidity, environmental influences Identifier An unambiguous reference to the resource within a given context 10.3390/ijerph17165634 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/41edf52a51934d0a4a36a3127a976a19.pdf e558a2c95f5de35cccef5ae2a32bf89a Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Biochemical and Computational Approach of Selected Phytocompounds from <i>Tinospora crispa</i> in the Management of COVID-19 Creator An entity primarily responsible for making the resource Jesus Simal-Gandara, Ahmed Rakib, Saad Ahmed Sami, Talha Bin Emran, Arkajyoti Paul, Abu Montakim Tareq, Md. Nazim Uddin Chy, Sumit Kumar Baral, Mohuya Majumder, Mohammad Nurul Amin, Asif Shahriar, Md. Zia Uddin, Mycal Dutta, Trina Ekawati Tallei Description An account of the resource A pandemic caused by the novel coronavirus (SARS-CoV-2 or COVID-19) began in December 2019 in Wuhan, China, and the number of newly reported cases continues to increase. More than 19.7 million cases have been reported globally and about 728,000 have died as of this writing (10 August 2020). Recently, it has been confirmed that the SARS-CoV-2 main protease (Mpro) enzyme is responsible not only for viral reproduction but also impedes host immune responses. The Mpro provides a highly favorable pharmacological target for the discovery and design of inhibitors. Currently, no specific therapies are available, and investigations into the treatment of COVID-19 are lacking. Therefore, herein, we analyzed the bioactive phytocompounds isolated by gas chromatography–mass spectroscopy (GC-MS) from Tinospora crispa as potential COVID-19 Mpro inhibitors, using molecular docking study. Our analyses unveiled that the top nine hits might serve as potential anti-SARS-CoV-2 lead molecules, with three of them exerting biological activity and warranting further optimization and drug development to combat COVID-19. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, SARS-CoV-2, Natural products, phytochemicals, secondary metabolites, <i>Tinospora crispa</i> Identifier An unambiguous reference to the resource within a given context 10.3390/molecules25173936 Source A related resource from which the described resource is derived Biotemas Publisher An entity responsible for making the resource available Universidade Federal de Santa Catarina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Organic chemistry