1041 10 20655 https://www.socictopen.socict.org/files/original/52352df3859dc53c5ecb0ac5431fac8e.pdf a1d63d850e4be4a0634aa73e391280d4 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Analysis of Discussions within the Chinese Society on China’s Position in World in the Context of Sino-American Relations Deterioration during the Pandemic Period Creator An entity primarily responsible for making the resource A. N. Karneev, A. S. Pyatachkova Description An account of the resource During the pandemic, Sino-US relations have remarkably deteriorated. The institutionalization of such destructive practices as toughening rhetoric in the media and sanctions is becoming obvious. As the model of bilateral relations is now aimed at decoupling the degradation will continue. These trends inevitably affect the mood of the Chinese society. The article analyzes opinions on foreign policy in Chinese society in the context of Sino American relations within the pandemic period. The work is divided into two parts: the first assesses general trends in US-China relations. The second part traces the current trends in the modern ideological and political atmosphere in Chinese society. The episode with congratulations to the Chinese public from the American administration on the occasion of the 101st anniversary of the famous «May 4, 1919 movement» is analyzed as a case study. The research shows that this event received ambiguous and even opposite assessments: part of the society saw in it as an attempt to accuse China of the spread of coronavirus and the imposition of Western values. Another part emphasized M. Pottinger’s rather high level of spoken Chinese and noted that the very fact of congratulation can be viewed as a positive moment for bilateral relations. There were also positions combining both approaches. The case under consideration reveals the danger of decoupling initiated by the parties. The tension between the PRC and the United States leads to the fact that the partners are starting to interpret each other’s intentions as presumably hostile, even taking into account such a formally favorable occasion as congratulations on a significant historical date. Meanwhile, it seems that the presence of positive interpretations against the background of a general deterioration in bilateral relations also cannot be ignored. Although public opinion cannot be unambiguous and does not always directly influence specific political steps, it is important to take into account the full range of opinions for an objective and comprehensive analysis of Sino American relations. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource coronavirus pandemic, Chinese Foreign Policy, Sino-American relations, foreign policy discussions within chinese society, may 4th movement, values and historical memory in chinese society Identifier An unambiguous reference to the resource within a given context 10.24411/2221-3279-2020-10054 Source A related resource from which the described resource is derived Sravnitelʹnaâ Politika Publisher An entity responsible for making the resource available Jurist, Publishing Group Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Political science (General) https://www.socictopen.socict.org/files/original/308186641af2a00395664e36ab59ed6c.pdf 053622bb14f57e645e7bc879ad3a894f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Association of Comorbidities with Coronavirus Disease 2019: A Review Creator An entity primarily responsible for making the resource Prasenjit Mitra, Smriti Suri, Taru Goyal, Radhieka Misra, Kuldeep Singh, M. K. Garg, Sanjeev Misra, Praveen Sharma Description An account of the resource The novel Coronavirus disease 2019 (COVID-19) pandemic started with few cases of pneumonia of unknown origin in Wuhan, China. It has now become one of the significant public health emergencies of all time. Within 5 months of its existence, it has led to a significant impact on national and international policies. Apart from being a medical emergency, it is also affecting the global economy, and without proper measures, it may have severely impact the socioeconomic statuses of individuals. It has profoundly challenged the healthcare infrastructure, particularly in low- and middle-income nations. Every nation is trying to safeguard its population and the health workers as adequately as possible. While we still wait for the development of an absolute cure in the form of a vaccine, preventive measures have taken the lead in reducing the disease spread and breaking the chain of transmission. The knowledge gained from the clinical characteristics of patients has suggested markers or comorbid conditions that may aid in the risk assessment. This narrative review aims to provide an update on SARS-CoV-2, the causative virus of COVID-19, its pathogenesis, the clinical and laboratory features, and its association with several comorbid conditions that may influence the prognosis of this disease. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, ACE2, diabetes, aging, Hypovitaminosis Identifier An unambiguous reference to the resource within a given context 10.1055/s-0040-1714159 Source A related resource from which the described resource is derived Annals of the National Academy of Medical Sciences (India) Publisher An entity responsible for making the resource available Thieme Medical and Scientific Publishers Pvt. Ltd. Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Science, General works https://www.socictopen.socict.org/files/original/2bb768f7c5109e2c4944a43874410a82.pdf 8bd147ce400b4508d3ce61bdf3db6e30 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Evaluation of the Usefulness of CO-RADS for Chest CT in Patients Suspected of Having COVID-19 Creator An entity primarily responsible for making the resource Tomoyuki Fujioka, Mio Mori, Koichiro Kimura, Ukihide Tateishi, Marie Takahashi, Junichi Tsuchiya, Emi Yamaga, Toshihiro Horii, Hirofumi Yamada, Mizuki Kimura, Yoshio Kitazume, Mitsuhiro Kishino Description An account of the resource The purpose of this study was to use the Coronavirus Disease 2019 (COVID-19) Reporting and Data System (CO-RADS) to evaluate the chest computed tomography (CT) images of patients suspected of having COVID-19, and to investigate its diagnostic performance and interobserver agreement. The Dutch Radiological Society developed CO-RADS as a diagnostic indicator for assessing suspicion of lung involvement of COVID-19 on a scale of 1 (very low) to 5 (very high). We investigated retrospectively 154 adult patients with clinically suspected COVID-19, between April and June 2020, who underwent chest CT and reverse transcription-polymerase chain reaction (RT-PCR). The patients’ average age was 61.3 years (range, 21–93), 101 were male, and 76 were RT-PCR positive. Using CO-RADS, four radiologists evaluated the chest CT images. Sensitivity, specificity, and area under the receiver operating characteristic curve (AUC) were calculated. Interobserver agreement was calculated using the intraclass correlation coefficient (ICC) by comparing the individual reader’s score to the median of the remaining three radiologists. The average sensitivity was 87.8% (range, 80.2–93.4%), specificity was 66.4% (range, 51.3–84.5%), and AUC was 0.859 (range, 0.847–0.881); there was no significant difference between the readers (p > 0.200). In 325 (52.8%) of 616 observations, there was absolute agreement among observers. The average ICC of readers was 0.840 (range, 0.800–0.874; p < 0.001). CO-RADS is a categorical taxonomic evaluation scheme for COVID-19 pneumonia, using chest CT images, that provides outstanding performance and from substantial to almost perfect interobserver agreement for predicting COVID-19. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, pneumonia, computed tomography, radiology, Chest imaging, CO-RADS Identifier An unambiguous reference to the resource within a given context 10.3390/diagnostics10090608 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine (General) https://www.socictopen.socict.org/files/original/6dea924b9c56a09008664c392de80050.pdf ee3051c95b7389c2dacac1873bf05bfb Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource E-Learning Critical Success Factors during the COVID-19 Pandemic: A Comprehensive Analysis of E-Learning Managerial Perspectives Creator An entity primarily responsible for making the resource Ammar Y. Alqahtani, Albraa A. Rajkhan Description An account of the resource During the COVID-19 pandemic, educational institutions were shut down all over the world, which impacted over 60% of students and caused a massive disruption of the education system. The goal of this paper was to identify the critical success factors for E-learning during COVID-19 using the multi-criteria Analytic Hierarchy Process (AHP) and Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) techniques to enhance the educational process. Data were generated by interviewing 69 E-learning managers in educational institutions during COVID-19 based on defined evaluation criteria and E-learning approaches through several channels. We found that technology management, support from management, increased student awareness to use E-learning systems, and demanding a high level of information technology from instructors, students, and universities were the most influential factors for E-learning during COVID-19. Among the five learning systems, blended learning was the most suitable learning system to practice. These results demonstrated that, regardless of how extraordinary the technology is in an educational institution, the readiness of E-learning execution played a large role in boosting the educational process during the COVID-19 pandemic. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource e-learning, distance learning, COVID-19 coronavirus pandemic, Critical Success Factors, AHP-TOPSIS Identifier An unambiguous reference to the resource within a given context 10.3390/educsci10090216 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Education https://www.socictopen.socict.org/files/original/ecab882fec7421deb8fa70da7dc0bd38.pdf e3fe558d96e13bc07f94c58bd48a3d89 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Are SAARC countries prepared to combat COVID-19 to save young, working-age population? Creator An entity primarily responsible for making the resource Farhana Sultana, Hasan Mahmud Reza Description An account of the resource The COVID-19 outbreak has expanded across the globe. Most of the countries are launching different measures to stop the transmission of this virus. However, the death toll is steadily rising. Strikingly the rate of coronavirus infection among the young-age population is the highest in SAARC countries as more than 80% population of the SAARC countries are young who constitute the working-age group. The disease transmission also occurs at a slower rate presumably due to diverse lifestyles of different ethnicities, immunity and genetic traits; but not because of the hot and humid weather despite previous assumptions. Since SAARC countries comprise 23.75% of the world population and the largest portion of these people is the young working-class, some immediate measures need to be implemented to save these valuable lives from COVID-19. Till now, there is no specific treatment or vaccine available; hence timely-taken preventive measures are the only hope that can save the people of this region. Here we have demonstrated an altered disease transmission pattern in people of SAARC countries, measures initiated by the governments, causes of failure and further actions to be taken to control disease transmission. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, climate, SAARC, young population Identifier An unambiguous reference to the resource within a given context 10.3934/publichealth.2020036 Source A related resource from which the described resource is derived Biotemas Publisher An entity responsible for making the resource available Universidade Federal de Santa Catarina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Public aspects of medicine https://www.socictopen.socict.org/files/original/5364194fc662d9d56716a93c904140c1.pdf 1177f2000f5ff69e4ad61b8db14acb8c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Sustainable Development of an Individual as a Result of Mutual Enrichment of Professional and Personal Life Creator An entity primarily responsible for making the resource Katarzyna Mikołajczyk Description An account of the resource Presently, the development of civilization requires a vision of balancing the interests of employees and employers in the sphere of work as never before. Work-life balance is directly linked to social sustainability. The aim of this article is to analyze various dimensions of mutual enrichment of the professional and private life of an individual and to describe how positive experiences in professional and non-professional life influence the improvement of satisfaction, health, and achievements, thus enabling the sustainable development of the individual. The conducted research was of a qualitative nature. Thematic exploration was used to analyze the findings of 34 in-depth interviews with experienced HR managers and employees at various levels of enterprises in Poland. The research shows that the work and personal life of the respondents interact, complement, and enrich in different ways, depending on the stage of the employee’s life. Habits developed by practicing a specific sport discipline or other type of hobby are helpful in the effective implementation of professional tasks. In addition, non-professional interests, including communing with culture and art, have a positive impact on professional activities. On the other hand, the respondents emphasized that thanks to their professional activities, specific to the type of work they perform, they are sometimes more extroverted, meticulous, organized, and consistent when performing activities outside of work and in other aspects of private life. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource covid-19 pandemic, Work Life Balance, work-life enrichment, outside-of-work activity, sustainable human capital development Identifier An unambiguous reference to the resource within a given context 10.3390/su13020697 Source A related resource from which the described resource is derived Biotemas Publisher An entity responsible for making the resource available Universidade Federal de Santa Catarina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Environmental effects of industries and plants, Renewable energy sources, Environmental sciences https://www.socictopen.socict.org/files/original/9866ae7d9e147a6fd277191ea71bd550.pdf 5f82a54d11dd643ad4458fe6cc834019 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Transitioning University Courses Online in Response to COVID-19 Creator An entity primarily responsible for making the resource David Michael Telles-Langdon Description An account of the resource As the world reeled from the realization that a pandemic of a magnitude not seen in a century was upon us, and that physical distancing to reduce the speed of transmission was going to necessitate suspension of regular classes, university faculty members scrambled to convert their planned lectures from in-person to online formats. This article describes one faculty member’s experiences using a flipped classroom approach in a virtual teaching environment. The arrival of COVID-19 fractured the school year and put some students’ graduation in jeopardy. From a hasty search of literature on the process of teaching and evaluating in an online environment, to a selection of hardware and software to provide students with an optimal learning environment while ensuring the security and validity of online evaluation, this article will highlight some of the successes and pitfalls of a rapid transition to online instruction and evaluation. Although there is a body of literature on the process and efficacy of online teaching, the constantly evolving nature of technology not only continues to produce new online instruction tools, but also tools that can be used by students to circumvent most cheating prevention measures put in place. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.22329/jtl.v14i1.6262 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Education https://www.socictopen.socict.org/files/original/cfa543982ca76081731395bef54deb9a.pdf 07422598f412ed63043a5a9c1873fde7 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Influence of Personal Respiratory and Visual Protective Equipment on the Development and Progression of Dry Eye Syndrome Creator An entity primarily responsible for making the resource A. V. Kuroyedov, P. Ch. Zavadski, A. Yu. Brezhnev, V. V. Gorodnichii, I. R. Gazizova, A. V. Seleznev, O. N. Onufriichuk, Yu. I. Razhko, Z. M. Nagornova Description An account of the resource Purpose. To study the influence of personal protective equipment (PPE) of the respiratory and visual systems on the development and progression of dry eye syndrome (DES) and its relationship with other risk factors for medical workers.Patients and methods. The data of 243 people (male — 22.2 %, female — 77.8 %) were analyzed as part of a multi-center analytical scientific one-step study. Total tear production (Schirmer I test) was studied at the beginning and the end of the working day in persons used PPE of respiratory system (disposable medical face mask, gauze masks or different types of respirators), as well as PPE of the eyes (protective half-closed/closed glasses or protective screens). Risk factors for the development and progression of DES were registered (age, smoking, systemic hormones intake, soft contact lenses), as well as the use of artificial tears.Results. A decrease in the Schirmer I test score at the end of a 7–8 hour work shift was found by an average of 3 mm (from 13 (9; 16) mm to 10 (6; 15) mm, p &lt; 0.001). Statistically significant changes were typical mainly for medical personnel (p &lt; 0.001) with the maximum severity in persons working in outpatient sector. The presence of at least one DES risk factor was found in 30.5 % of patients, two factors — in 3.0 %, and three or more — in 7.0 %. There was no influence of risk factors on the degree of changes in total tear production. Reduced tear production is typical for some PPE of respiratory system (disposable masks and respirators) and the eye (screens and half-closed glasses) (p &lt; 0.001). In people who do not use PPE of the eye, significant changes were detected only in the presence of risk factors.Conclusion. The negative influence of various PPE of the respiratory system and eye on the total tear production was established. The decrease in the results of the Schirmer I test by the end of the working day was 20–25 % of the basic level, regardless of the presence of traditional risk factors for DES. The severity of changes depended on the type of PPE used. The data obtained are particularly relevant during the new COVID-19 coronavirus pandemic and justify the need to establish specific prophylactic measures. One of the possible methods is the preventive use of artificial tears. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, Personal protective equipment, dry eye syndrome Identifier An unambiguous reference to the resource within a given context 10.18008/1816-5095-2020-3-519-526 Source A related resource from which the described resource is derived Biotemas Publisher An entity responsible for making the resource available Universidade Federal de Santa Catarina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Ophthalmology https://www.socictopen.socict.org/files/original/09e630035f311dfb69c06d3c6351751d.pdf 009169040296c74b10b008f92bb25cf6 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource An engaged university: Rescuing SMES during the COVID-19 crisis Creator An entity primarily responsible for making the resource Daniela Francisco Brauner, Fernanda Maciel Reichert, Raquel Janissek-Muniz, Aurora Carneiro Zen, Daniela Callegaro de Menezes, Lisiane Quadrado Closs, Wendy Beatriz Witt Haddad Carraro, Carla Simone Ruppenthal, Fernanda Maria Müller, Marcelo Soares Lubaszewski, Marisa Ignez S. Rhoden Description An account of the resource The economic effects of isolation policies resulting from the COVID-19 pandemic have led small and medium-sized enterprises (SMEs) to look for alternatives to survive. Within this crisis scenario, an engaged university has an important role to play in a regional context in addressing not only health issues, but also any resultant social and economic problems. An engaged university needs to take actions that go beyond its traditional missions of education and research - it has to deliver knowledge to society. This paper analyzes a university-community project in Brazil to identify the necessary elements that help promote a regionally-engaged university: the SOS-PME Advisory Network project, which was originally designed to assist SMEs during the crisis. As a result, we identified elements necessary for promoting the university’s third mission - social engagement by way of a university-community project: an engaged team, multidisciplinarity, project management, agility, alliances, a communication strategy, institutional support, and reputation. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, engagement, project management, SMEs, engaged university Identifier An unambiguous reference to the resource within a given context http://dx.doi.org/10.1590/S0034-759020200607 Source A related resource from which the described resource is derived RAE: Revista de Administração de Empresas Publisher An entity responsible for making the resource available Fundação Getulio Vargas Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Business https://www.socictopen.socict.org/files/original/372bc84d2ae39f1d19ccab81930127fc.pdf 7b365b6d5c3681ec06dbe4ed339b4250 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A Putative Prophylactic Solution for COVID-19: Development of Novel Multiepitope Vaccine Candidate against SARS-COV-2 by Comprehensive Immunoinformatic and Molecular Modelling Approach Creator An entity primarily responsible for making the resource Muhammad Usman Mirza, Matheus Froeyen, Huda Ahmed Alghamdi, Hafiz Muzzammel Rehman, Mian Azhar Ahmad, Mahjabeen Saleem, Sarfraz Ahmad, Roquyya Gul, Muhammad Shahbaz Aslam, Muhammad Sajjad, Munir Ahmad Bhinder Description An account of the resource The outbreak of 2019-novel coronavirus (SARS-CoV-2) that causes severe respiratory infection (COVID-19) has spread in China, and the World Health Organization has declared it a pandemic. However, no approved drug or vaccines are available, and treatment is mainly supportive and through a few repurposed drugs. The urgency of the situation requires the development of SARS-CoV-2-based vaccines. Immunoinformatic and molecular modelling are time-efficient methods that are generally used to accelerate the discovery and design of the candidate peptides for vaccine development. In recent years, the use of multiepitope vaccines has proved to be a promising immunization strategy against viruses and pathogens, thus inducing more comprehensive protective immunity. The current study demonstrated a comprehensive in silico strategy to design stable multiepitope vaccine construct (MVC) from B-cell and T-cell epitopes of essential SARS-CoV-2 proteins with the help of adjuvants and linkers. The integrated molecular dynamics simulations analysis revealed the stability of MVC and its interaction with human Toll-like receptors (TLRs), which trigger an innate and adaptive immune response. Later, the in silico cloning in a known pET28a vector system also estimated the possibility of MVC expression in Escherichia coli. Despite that this study lacks validation of this vaccine construct in terms of its efficacy, the current integrated strategy encompasses the initial multiple epitope vaccine design concepts. After validation, this MVC can be present as a better prophylactic solution against COVID-19. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Multi-epitope Vaccine, spike protein, covid-19, SARS-CoV-2, molecular modeling Identifier An unambiguous reference to the resource within a given context 10.3390/biology9090296 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General)