1050 10 20655 https://www.socictopen.socict.org/files/original/868d5770940b9bfbe26757a3c2093caa.pdf 09f5c77e0182b3babc2fe6ee2a0d2c94 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource An Italian Neurology Outpatient Clinic Facing SARS-CoV-2 Pandemic: Data From 2,167 Patients Creator An entity primarily responsible for making the resource Paolo Calabresi, Carla Piano, Enrico Di Stasio, Enrico Di Stasio, Guido Primiano, Delfina Janiri, Delfina Janiri, Marco Luigetti, Marco Luigetti, Giovanni Frisullo, Catello Vollono, Catello Vollono, Matteo Lucchini, Matteo Lucchini, Valerio Brunetti, Mauro Monforte, Valeria Guglielmi, Giacomo Della Marca, Giacomo Della Marca, Amelia Evoli, Amelia Evoli, Camillo Marra, Camillo Marra, Massimiliano Mirabella, Massimiliano Mirabella, Davide Quaranta, Davide Quaranta, Enzo Ricci, Enzo Ricci, Serenella Servidei, Serenella Servidei, Gabriella Silvestri, Gabriella Silvestri, Simone Bellavia, Sara Bortolani, Francesco Bove, Riccardo Di Iorio, Andrea Di Paolantonio, Danilo Genovese, Tamara Ialongo, Maria Rita Lo Monaco, Jessica Marotta, Agata Katia Patanella, Alessia Perna, Martina Petracca, Giorgia Presicce, Vittorio Riso, Eleonora Rollo, Angela Romano, Marina Romozzi, Cristina Sancricca, Irene Scala, Gregorio Spagni, Marcella Solito, Luca Tricoli, Paola Zinzi, Paolo Calabresi, Anna Rita Bentivoglio, Anna Rita Bentivoglio Description An account of the resource Objective: Neurological sequelae of SARS-CoV-2 infection have already been reported, but there is insufficient data about the impact of the pandemic on the management of the patients with chronic neurological diseases. We aim to analyze the effect of COVID-19 pandemic and social restriction rules on these fragile patients.Methods: Patients with chronic neurologic diseases routinely followed at the outpatient clinic of Gemelli University Hospital, Rome, were assessed for symptoms suggestive of SARS-CoV-2 infection in the pandemic period, consequences of social restrictions, and neurological disease features, concomitant medical conditions, current medical and disease-specific treatments. Data source: a dedicated telephone survey designed to encompass questions on COVID-19 symptoms and on pandemic effects in chronic neurologic conditions.Results: Overall, 2,167 individuals were analyzed: 63 patients reported contact with COVID-19 positive cases, 41 performed the swab, and 2 symptomatic patients tested positive for COVID-19 (0.09%). One hundred fifty-eight individuals (7%) needed urgent neurological care, deferred due to the pandemic; 641 patients (30%) suspended hospital treatments, physiotherapy or other support interventions; 405 individuals (19%) reported a subjective worsening of neurological symptoms.Conclusions: In our population, the presence of neurological chronic diseases did not increase the prevalence of COVID-19 infection. Nevertheless, the burden of neurological disorders has been worsened by the lockdown. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource coronavirus, covid-19, Pandemic, infection, health care, neurology Identifier An unambiguous reference to the resource within a given context 10.3389/fneur.2020.00564 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Neurology. Diseases of the nervous system https://www.socictopen.socict.org/files/original/72591034ca3fcaa414e8bc466f719b81.pdf 215060e40df4ba574f5ea9b458a65c29 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource HLA, Immune Response, and Susceptibility to COVID-19 Creator An entity primarily responsible for making the resource Gholamreza Hatam, Ahmad Zavaran Hosseini, Marjan Jeddi, Fataneh Tavasolian, Mohsen Rashidi, Sayed Hussain Mosawi, Sayed Hussain Mosawi, Elham Abdollahi, Robert D. Inman, Robert D. Inman Description An account of the resource The severe acute respiratory syndrome caused by Coronavirus 2 (SARS-CoV-2) that appeared in December 2019 has precipitated the global pandemic Coronavirus Disease 2019 (COVID-19). However, in many parts of Africa fewer than expected cases of COVID-19, with lower rates of mortality, have been reported. Individual human leukocyte antigen (HLA) alleles can affect both the susceptibility and the severity of viral infections. In the case of COVID-19 such an analysis may contribute to identifying individuals at higher risk of the disease and the epidemiological level to understanding the differences between countries in the epidemic patterns. It is also recognized that first antigen exposure influences the consequence of subsequent exposure. We thus propose a theory incorporating HLA antigens, the “original antigenic sin (OAS)” effect, and presentation of viral peptides which could explain with differential susceptibility or resistance to SARS-CoV-2 infections. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource Coronavirus disease 2019, immune response, vaccine design, human leukocyte antigens, original antigenic sin Identifier An unambiguous reference to the resource within a given context 10.3389/fimmu.2020.601886 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Immunologic diseases. Allergy https://www.socictopen.socict.org/files/original/cad32c8b9fbc2dbb259518d1a11e8ed1.pdf 247d83160b12b51072d53faf7f8b7221 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Social, Psychological, and Philosophical Reflections on Pandemics and Beyond Creator An entity primarily responsible for making the resource Abraham Rudnick Description An account of the resource This conceptual paper presents social, psychological and philosophical (ethical and epistemological) reflections regarding the current (COVID-19) pandemic and beyond, using an analytic and comparative approach. For example, Taiwan and Canada are compared, addressing Taiwan’s learning from SARS. Suggestions are made in relation to current and future relevant practice, policy, research and education. For example, highly exposed individuals and particularly vulnerable populations, such as health care providers and socially disadvantaged (homeless and other) people, respectively, are addressed as requiring special attention. In conclusion, more reflection on and study of social and psychological challenges as well as underlying philosophical issues related to the current pandemic and more generally to global crises is needed. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource practice, Pandemic, education, policy, Psychology, Philosophy Identifier An unambiguous reference to the resource within a given context 10.3390/soc10020042 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Social sciences (General) https://www.socictopen.socict.org/files/original/7d0cba10a4d3faf4a035c4c8b90ed2e8.pdf ff4ddd87414e17d91f2166ee6f9aa476 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource An Overview of the Most Significant Zoonotic Viral Pathogens Transmitted from Animal to Human in Saudi Arabia Creator An entity primarily responsible for making the resource Omar A. Al-Tayib Description An account of the resource Currently, there has been an increasing socioeconomic impact of zoonotic pathogens transmitted from animals to humans worldwide. Recently, in the Arabian Peninsula, including in Saudi Arabia, epidemiological data indicated an actual increase in the number of emerging and/or reemerging cases of several viral zoonotic diseases. Data presented in this review are very relevant because Saudi Arabia is considered the largest country in the Peninsula. We believe that zoonotic pathogens in Saudi Arabia remain an important public health problem; however, more than 10 million Muslim pilgrims from around 184 Islamic countries arrive yearly at Makkah for the Hajj season and/or for the Umrah. Therefore, for health reasons, several countries recommend vaccinations for various zoonotic diseases among preventive protocols that should be complied with before traveling to Saudi Arabia. However, there is a shortage of epidemiological data focusing on the emerging and reemerging of zoonotic pathogens transmitted from animal to humans in different densely populated cities and/or localities in Saudi Arabia. Therefore, further efforts might be needed to control the increasing impacts of zoonotic viral disease. Also, there is a need for a high collaboration to enhance the detection and determination of the prevalence, diagnosis, control, and prevention as well as intervention and reduction in outbreaks of these diseases in Saudi Arabia, particularly those from other countries. Persons in the health field including physicians and veterinarians, pet owners, pet store owners, exporters, border guards, and people involved in businesses related to animal products have adopted various preventive strategies. Some of these measures might pave the way to highly successful prevention and control results on the different transmission routes of these viral zoonotic diseases from or to Saudi Arabia. Moreover, the prevention of these viral pathogens depends on socioeconomic impacts, available data, improved diagnosis, and highly effective therapeutics or prophylaxis. Date A point or period of time associated with an event in the lifecycle of the resource 2019 Subject The topic of the resource MERS-CoV, Saudi Arabia, Zoonosis, Public health, Animal, viral pathogens, AHFV, Hajj and Umrah Identifier An unambiguous reference to the resource within a given context 10.3390/pathogens8010025 Source A related resource from which the described resource is derived Biotemas Publisher An entity responsible for making the resource available Universidade Federal de Santa Catarina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/66f9a392cbf33e10a894c0686d197dd3.pdf 297f69dbaab8d14b8b736e764434d272 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Covid-19 Salgın Döneminde Hava Taşımacılığının Yeniden Başlatılması: Yolcuları ve Havacılık Personelini Korumak için Temel Önlemler Creator An entity primarily responsible for making the resource Yeşim Kurt Description An account of the resource Bu çalışmanın konusu Covid-19 virüsüne karşı hava taşımacılığında alınan önlemlerdir. Araştırmanın amacı, Covid-19 salgını sürecinde hava taşımacılığında müşteriler ve insan kaynağı için ne tür önlemler alındığını ortaya koymaktır. Bu amaca ulaşmak adına ikincil veri kaynaklarından olan belge incelmesinden yararlanılmıştır. Konuyla ilgili olarak elde edilen veriler tümevarımsal biçimde analiz edilmiştir. Analiz sonucunda ortaya çıkan önlemler, yolculara yönelik ve çalışanlara yönelik olmak üzere iki ana temada tartışılmıştır. Yolculara yönelik önlemler üç kategoriden oluşmaktadır. Bunlar havalimanına gelmeden önce alınan önlemler, havalimanında alınan önlemler ve uçak içinde alınan önlemlerdir. Çalışanlara yönelik önlemler ise iki alt kategoriyle açıklanmaktadır. Bunlar yerde görevli personele yönelik önlemler ve uçuş görevlilerine yönelik önlemlerdir.Bu araştırmayla çerçevesi çizilen önlemler, havacılık işletmelerinin bu krizin üstesinden gelebilmesinde kritik öneme sahiptir. Bu önlemler havacılık işletmelerinin hem yolcuların hem de çalışanların gözünde güvenilir oldukları yönünde bir imaj yaratacak ve itibarlarını kazanmalarına katkı sağlayacaktır. Hava taşımacılığında risklerin yönetilebildiği konusunda ikna olan müşteriler bilet satın alarak havalimanlarına ve havayollarına yolcu olarak değer katacaklardır. İnsan kaynaklarına yönelik önlemler ise çalışanların güvende hissetmelerine katkı sağlayarak; baskı altında hissetmeden, motive edilmiş bir şekilde çalışarak verimliliklerini sürdürmelerine katkı sağlayacaktır. Hem çalışanlar hem de müşteriler gözünde yaratılan bu fark, işletmelerin bu krizin üstesinden gelmelerine ve sürdürülebilirliklerine doğrudan katkı sağlayacaktır. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, human resources, Air Transportation, Risk yönetimi, İnsan kaynakları, halk sağlığı, risk maganement, publich healt, hava taşımacılığı Identifier An unambiguous reference to the resource within a given context 10.21547/jss.758434 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Social sciences (General), Social Sciences https://www.socictopen.socict.org/files/original/656a8348d2e8bd3bd8b0b50b074d874b.pdf e3fe558d96e13bc07f94c58bd48a3d89 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus disease 2019 in children: Clinical & epidemiological implications Creator An entity primarily responsible for making the resource Vijesh Sreedhar Kuttiatt, Philip Raj Abraham, Ramesh P Menon, Pankaj C Vaidya, Manju Rahi Description An account of the resource Despite the global spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, there are limited data emerging in children. This review provides an update on clinical features, diagnosis, epidemiology, management and prevention of coronavirus disease 2019 (COVID-19) in children. Specific characteristics noted in children and their implications in disease management as well as transmission control are highlighted. Besides respiratory symptoms, gastrointestinal and atypical features such as chilblains, neurological symptoms and multisystem inflammation are also reported. Younger infants and those with comorbidity were found to be at risk of severe illness. Infected pregnant women and neonates were reported to have good prognosis. It is possible to manage the children with mild disease at home, with strict infection prevention control measures; severely affected require respiratory support and intensive care management. There are anecdotal reports of using antiviral and immunomodulatory drugs, benefit of which needs to be confirmed in clinical trials. A significant percentage of asymptomatic infection in children has epidemiological implication as these may act as links in transmission chain in the community. There is a need for systematic data on extra-pulmonary manifestations and atypical features, risk factors of severity, role of imaging and biomarkers, testing and management strategies and trials with antivirals and immunomodulatory drugs in children. The psychosocial effects of quarantine, closure of schools, lack of play activities and impact of lockdown need to be addressed. Understanding the biological basis for the profound age-dependent differential outcome of COVID-19 infection is important. Elucidating the protective mechanisms in children may aid in developing novel treatment strategies. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource children - clinical features - covid-2019 - epidemiology - prevention - sars-cov-2 - severity of illness - treatment Identifier An unambiguous reference to the resource within a given context 10.4103/ijmr.IJMR_977_20 Source A related resource from which the described resource is derived Biotemas Publisher An entity responsible for making the resource available Universidade Federal de Santa Catarina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/64c222c2ce09e3108d76a7d5cc9e8fe5.pdf 75fde4a478d42afe3cb8889b11e3c4e6 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Dental practice during the COVID.19 pandemic: Challenges and the way forward Creator An entity primarily responsible for making the resource Byalakere Rudraiah Chandrashekar, S Suma, A Bhagyalakshmi Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context 10.4103/CRST.CRST_312_20 Source A related resource from which the described resource is derived Cancer Research, Statistics, and Treatment Publisher An entity responsible for making the resource available Wolters Kluwer Medknow Publications Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Neoplasms. Tumors. Oncology. Including cancer and carcinogens https://www.socictopen.socict.org/files/original/ef74d0a60f0bda2d6854df5459c32c50.pdf e4c2e21369d5fe739de0128c0808b265 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Epidemiology of COVID-19 Creator An entity primarily responsible for making the resource Selma Metintas Description An account of the resource Acknowledging the epidemiological parameters is essential in the control of coronavirus disease 2019, which has been declared a pandemic by the World Health Organization. To define the macroscopic behavior and control of the disease in the society, the incubation period, serial interval, reproductive coefficient, doubling time of the infection, growth rate, curve flattening index, case fatality rate, and the rate of asymptomatic cases should be well known. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource epidemiology, Pandemic, Coronavirus disease 2019 Identifier An unambiguous reference to the resource within a given context 10.4103/ejop.ejop_55_20 Source A related resource from which the described resource is derived Eurasian Journal of Pulmonology Publisher An entity responsible for making the resource available Wolters Kluwer Medknow Publications Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Internal medicine https://www.socictopen.socict.org/files/original/efad65b3a973de214eae5350e1774617.pdf d4160c80d25db872c90486e5d5d217f7 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Clinical Trials for Use of Melatonin to Fight against COVID-19 Are Urgently Needed Creator An entity primarily responsible for making the resource Konrad Kleszczyński, Andrzej T. Slominski, Russel J. Reiter, Kerstin Steinbrink Description An account of the resource The recent pandemic of COVID-19 has already infected millions of individuals and has resulted in the death of hundreds of thousands worldwide. Based on clinical features, pathology, and the pathogenesis of respiratory disorders induced by this and other highly homogenous coronaviruses, the evidence suggests that excessive inflammation, oxidation, and an exaggerated immune response contribute to COVID-19 pathology; these are caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This leads to a cytokine storm and subsequent progression triggering acute lung injury (ALI)/acute respiratory distress syndrome (ARDS), and often death. We and others have reported melatonin to be an anti-inflammatory and anti-oxidative molecule with a high safety profile. It is effective in critical care patients by reducing their vascular permeability and anxiety, inducing sedation, and improving their quality of sleep. As melatonin shows no harmful adverse effects in humans, it is imperative to introduce this indoleamine into clinical trials where it might be beneficial for better clinical outcomes as an adjuvant treatment of COVID-19-infected patients. Herein, we strongly encourage health care professionals to test the potential of melatonin for targeting the COVID-19 pandemic. This is urgent, since there is no reliable treatment for this devastating disease. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource inflammation, covid-19, Clinical trials, immune response, melatonin Identifier An unambiguous reference to the resource within a given context 10.3390/nu12092561 Source A related resource from which the described resource is derived Biotemas Publisher An entity responsible for making the resource available Universidade Federal de Santa Catarina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Nutrition. Foods and food supply https://www.socictopen.socict.org/files/original/c7bd1f0f526b95ab9c70375c70f730ef.pdf 20b8212560e920ac3700c36ffcd2ec47 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Predictors of fatality including radiographic findings in adults with COVID-19 Creator An entity primarily responsible for making the resource Kaiyan Li, Dian Chen, Shengchong Chen, Yuchen Feng, Chenli Chang, Zi Wang, Nan Wang, Guohua Zhen Description An account of the resource Abstract Background Older age and elevated d-dimer are reported risk factors for coronavirus disease 2019 (COVID-19). However, whether early radiographic change is a predictor of fatality remains unknown. Methods We retrospectively reviewed records of all laboratory-confirmed patients admitted to a quarantine unit at Tongji Hospital, a large regional hospital in Wuhan, China, between January 31 and March 5, 2020. Confirmed cases were defined by positive RT-PCR detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in throat-swab specimens. Chest CT images were reviewed independently by two radiologists. The Tongji Hospital ethics committee approved this study. Results A total of 102 patients were confirmed to have SARS-CoV-2 infection. As of March 25, 85 confirmed patients were discharged, 15 died, and 2 remained hospitalized. When compared with survivors, non-survivors were older (median age, 69 [interquartile range, 58–77] vs. 55 [44–66], p = 0.003), and more likely to have decreased lymphocyte count (0.5 vs. 0.9 ×  109/L, p = 0.006), elevated lactate dehydrogenase (LDH) (569.0 vs. 272.0 U/L, p  1 μg/mL, 86% vs. 37%, p = 0.002) on admission. Older age and elevated LDH were independent risk factors for fatality in a multivariate regression model included the above variables. In a subset of patients with CT images within the first week, higher total severity score, and more involved lung lobes (5 involved lobes) in CT images within the first week were significantly associated with fatality. Moreover, in this subset of patients, higher total severity score was the only independent risk factor in a multivariate analysis incorporating the above mentioned variables. Conclusions Older age, elevated LDH on admission, and higher severity score of CT images within the first week are potential predictors of fatality in adults with COVID-19. These predictors may help clinicians identify patients with a poor prognosis at an early stage. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, Fatality, Predictor, Radiographic findings Identifier An unambiguous reference to the resource within a given context 10.1186/s12931-020-01411-2 Source A related resource from which the described resource is derived Biotemas Publisher An entity responsible for making the resource available Universidade Federal de Santa Catarina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Diseases of the respiratory system