106 10 20655 https://www.socictopen.socict.org/files/original/c3db8906f5169f710a578b9eb9107029.pdf e15db44636e51adf9a7289b958c743cd Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Hospital Preparedness and SARS Creator An entity primarily responsible for making the resource Mona R Loutfy, Tamara Wallington, Tim Rutledge, Barbara Mederski, Keith Rose, Sue Kwolek, Donna McRitchie, Azra Ali, Bryan Wolff, Diane White, Edward Glassman, Marianna Ofner, Don E. Low, Lisa Berger, Allison McGeer, Tom Wong, David Baron, Glenn Berall Description An account of the resource On May 23, 2003, Toronto experienced the second phase of a severe acute respiratory syndrome (SARS) outbreak. Ninety cases were confirmed, and >620 potential cases were managed. More than 9,000 persons had contact with confirmed or potential case-patients; many required quarantine. The main hospital involved during the second outbreak was North York General Hospital. We review this hospital’s response to, and management of, this outbreak, including such factors as building preparation and engineering, personnel, departmental workload, policies and documentation, infection control, personal protective equipment, training and education, public health, management and administration, follow-up of SARS patients, and psychological and psychosocial management and research. We also make recommendations for other institutions to prepare for future outbreaks, regardless of their origin. Date A point or period of time associated with an event in the lifecycle of the resource 2004 Subject The topic of the resource severe acute respiratory syndrome, Outbreak, hospital, Management, Canada Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid1005.030717 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/634b051701a72e9d9cdc0a0e3fbadd95.pdf a29fc8a13f0d4b93efdd23c2e1cdba44 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Social Factors Associated with AIDS and SARS Creator An entity primarily responsible for making the resource Don C. Des Jarlais, Jennifer Stuber, Melissa Tracy, Susan Tross, Sandro Galea Description An account of the resource We conducted a survey of 928 New York City area residents to assess knowledge and worry about AIDS and SARS. Specific sociodemographic groups of persons were more likely to be less informed and more worried about contracting the diseases. Date A point or period of time associated with an event in the lifecycle of the resource 2005 Subject The topic of the resource stigmatization, Aids, SARS, Mental health, dispatch, United States Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid1111.050424 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/7b902ae4bea9a50fec11b26cc046ed48.pdf c738d8b44bfca72e9f48733f6ceece4a Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource SARS Coronavirus Detection Creator An entity primarily responsible for making the resource Andreas Nitsche, Brunhilde Schweiger, Heinz Ellerbrok, Matthias Niedrig, Georg Pauli Description An account of the resource We developed a set of three real-time reverse transcription–polymerase chain reaction (PCR) assays that amplify three different regions of the SARS-associated coronavirus (SARS-CoV), can be run in parallel or in a single tube, and can detect Date A point or period of time associated with an event in the lifecycle of the resource 2004 Subject The topic of the resource coronavirus, SARS, Real-time RT-PCR, molecular diagnostics Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid1007.030678 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/438b5ad9555e6272506908cdd4d98b46.pdf 03f62ae15a901c0ece35331b8ddb32ea Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Acute Middle East Respiratory Syndrome Coronavirus Infection in Livestock Dromedaries, Dubai, 2014 Creator An entity primarily responsible for making the resource Sung Sup Park, Ulrich Wernery, Victor M. Corman, Emily Y.M. Wong, Alan K.L. Tsang, Doreen Muth, Susanna K. P. Lau, Kamal Khazanehdari, Florian Zirkel, Mansoor Ali, Péter Nagy, Jutka Juhasz, Renate Wernery, Sunitha Joseph, Ginu Syriac, Shyna K. Elizabeth, Nissy Annie Georgy Patteril, Patrick C. Y. Woo, Christian Drosten Description An account of the resource Camels carry Middle East respiratory syndrome coronavirus, but little is known about infection age or prevalence. We studied >800 dromedaries of all ages and 15 mother–calf pairs. This syndrome constitutes an acute, epidemic, and time-limited infection in camels Date A point or period of time associated with an event in the lifecycle of the resource 2015 Subject The topic of the resource MERS-CoV, Middle East respiratory syndrome coronavirus, camels, coronavirus, Viruses, Dubai Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid2106.150038 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/63109bc18239f7e66d786a4cff19de04.pdf 9c715884f572f2db1862387ea94a4d69 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Antibody Response and Disease Severity in Healthcare Worker MERS Survivors Creator An entity primarily responsible for making the resource Abeer N. Alshukairi, Imran Khalid, Waleed A. Ahmed, Ashraf M. Dada, Daniyah T. Bayumi, Laut S. Malic, Sahar Al Thawadi, Kim Ignacio, Hanadi S. Alsalmi, Hail M. Al-Abdely, Ghassan Y. Wali, Ismael A. Qushmaq, Basem M. Alraddadi, Stanley Perlman Description An account of the resource We studied antibody response in 9 healthcare workers in Jeddah, Saudi Arabia, who survived Middle East respiratory syndrome, by using serial ELISA and indirect immunofluorescence assay testing. Among patients who had experienced severe pneumonia, antibody was detected for >18 months after infection. Antibody longevity was more variable in patients who had experienced milder disease. Date A point or period of time associated with an event in the lifecycle of the resource 2016 Subject The topic of the resource Antibody, Middle East respiratory syndrome coronavirus, MERS-CoV, ELISA, Indirect immunofluorescence assay, IFA Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid2206.160010 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/5ca7043b6c4edadb2559d45013958554.pdf 4b240d4a4fdb64b2bfc56a4836b4c363 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource International Health Regulations—What Gets Measured Gets Done Creator An entity primarily responsible for making the resource Kashef Ijaz, Eric Kasowski, Ray R. Arthur, Frederick J. Angulo, Scott F. Dowell Description An account of the resource The global spread of severe acute respiratory syndrome highlighted the need to detect and control disease outbreaks at their source, as envisioned by the 2005 revised International Health Regulations (IHR). June 2012 marked the initial deadline by which all 194 World Health Organization (WHO) member states agreed to have IHR core capacities fully implemented for limiting the spread of public health emergencies of international concern. Many countries fell short of these implementation goals and requested a 2-year extension. The degree to which achieving IHR compliance will result in global health security is not clear, but what is clear is that progress against the threat of epidemic disease requires a focused approach that can be monitored and measured efficiently. We developed concrete goals and metrics for 4 of the 8 core capacities with other US government partners in consultation with WHO and national collaborators worldwide. The intent is to offer an example of an approach to implementing and monitoring IHR for consideration or adaptation by countries that complements other frameworks and goals of IHR. Without concrete metrics, IHR may waste its considerable promise as an instrument for global health security against public health emergencies. Date A point or period of time associated with an event in the lifecycle of the resource 2012 Subject The topic of the resource International Health Regulations, monitoring and evaluation, implementation, IHR, Disease notification, Public Health Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid1807.120487 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/4e62fa4309176477de5db03eb91a91e0.pdf 7d375950f9150c6b8133dfc925563364 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Severe Respiratory Illness Outbreak Associated with Human Coronavirus NL63 in a Long-Term Care Facility Creator An entity primarily responsible for making the resource Julie Hand, Erica Billig Rose, Andrea Salinas, Xiaoyan Lu, Senthil Kumar K. Sakthivel, Eileen Schneider, John T. Watson Description An account of the resource We describe an outbreak of severe respiratory illness associated with human coronavirus NL63 in a long-term care facility in Louisiana in November 2017. Six of 20 case-patients were hospitalized with pneumonia, and 3 of 20 died. Clinicians should consider human coronavirus NL63 for patients in similar settings with respiratory disease. Date A point or period of time associated with an event in the lifecycle of the resource 2018 Subject The topic of the resource Outbreak, coronavirus, long-term care facility, Respiratory Infections, Louisiana, USA Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid2410.180862 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/ec84ae66d692d17a0678fd6fc2878b20.pdf e5bf486d5e8d1648e28c688256141a61 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Novel Avian Coronavirus and Fulminating Disease in Guinea Fowl, France Creator An entity primarily responsible for making the resource Etienne Liais, Guillaume Croville, Jérôme Mariette, Maxence Delverdier, Marie-Noëlle Lucas, Christophe Klopp, Jérôme Lluch, Cécile Donnadieu, James S. Guy, Léni Corrand, Mariette F. Ducatez, Jean-Luc Guérin Description An account of the resource For decades, French guinea fowl have been affected by fulminating enteritis of unclear origin. By using metagenomics, we identified a novel avian gammacoronavirus associated with this disease that is distantly related to turkey coronaviruses. Fatal respiratory diseases in humans have recently been caused by coronaviruses of animal origin. Date A point or period of time associated with an event in the lifecycle of the resource 2014 Subject The topic of the resource coronavirus, Guineafowl, metagenomics, Next-generation sequencing, Viruses, France Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid2001.130774 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/a73935bcd3dafcad901cef6401141543.pdf 65ed04a1a792143a96403960c1c1f4e6 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource MERS Coronavirus Neutralizing Antibodies in Camels, Eastern Africa, 1983–1997 Creator An entity primarily responsible for making the resource Marcel A. Müller, Victor Max Corman, Joerg Jores, Benjamin Meyer, Mario Younan, Anne M. Liljander, Berend-Jan Bosch, Erik Lattwein, Mosaad Hilali, Bakri E. Musa, Set Bornstein, Sung Sup Park Description An account of the resource To analyze the distribution of Middle East respiratory syndrome coronavirus (MERS-CoV)–seropositive dromedary camels in eastern Africa, we tested 189 archived serum samples accumulated during the past 30 years. We identified MERS-CoV neutralizing antibodies in 81.0% of samples from the main camel-exporting countries, Sudan and Somalia, suggesting long-term virus circulation in these animals. Date A point or period of time associated with an event in the lifecycle of the resource 2014 Subject The topic of the resource dromedary camel, reservoir, Middle East respiratory syndrome (MERS), coronavirus, Antibody, Viruses Identifier An unambiguous reference to the resource within a given context DOI: 10.3201/eid2012.141026 Source A related resource from which the described resource is derived Emerging Infectious Diseases Publisher An entity responsible for making the resource available Centers for Disease Control and Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/adaf9510fbf69c08fe4b4492d59248d4.pdf c47ec33e27f3ffcfc8bf46b44f568e5c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner. Creator An entity primarily responsible for making the resource Christine Burkard, Monique H. Verheije, Oliver Wicht, Sander I. van Kasteren, Frank J van Kuppeveld, Bart L. Haagmans, Lucas Pelkmans, Peter J.M. Rottier, Berend-Jan Bosch, Cornelis A.M. De Haan Description An account of the resource Enveloped viruses need to fuse with a host cell membrane in order to deliver their genome into the host cell. While some viruses fuse with the plasma membrane, many viruses are endocytosed prior to fusion. Specific cues in the endosomal microenvironment induce conformational changes in the viral fusion proteins leading to viral and host membrane fusion. In the present study we investigated the entry of coronaviruses (CoVs). Using siRNA gene silencing, we found that proteins known to be important for late endosomal maturation and endosome-lysosome fusion profoundly promote infection of cells with mouse hepatitis coronavirus (MHV). Using recombinant MHVs expressing reporter genes as well as a novel, replication-independent fusion assay we confirmed the importance of clathrin-mediated endocytosis and demonstrated that trafficking of MHV to lysosomes is required for fusion and productive entry to occur. Nevertheless, MHV was shown to be less sensitive to perturbation of endosomal pH than vesicular stomatitis virus and influenza A virus, which fuse in early and late endosomes, respectively. Our results indicate that entry of MHV depends on proteolytic processing of its fusion protein S by lysosomal proteases. Fusion of MHV was severely inhibited by a pan-lysosomal protease inhibitor, while trafficking of MHV to lysosomes and processing by lysosomal proteases was no longer required when a furin cleavage site was introduced in the S protein immediately upstream of the fusion peptide. Also entry of feline CoV was shown to depend on trafficking to lysosomes and processing by lysosomal proteases. In contrast, MERS-CoV, which contains a minimal furin cleavage site just upstream of the fusion peptide, was negatively affected by inhibition of furin, but not of lysosomal proteases. We conclude that a proteolytic cleavage site in the CoV S protein directly upstream of the fusion peptide is an essential determinant of the intracellular site of fusion. Date A point or period of time associated with an event in the lifecycle of the resource 2014 Identifier An unambiguous reference to the resource within a given context DOI: 10.1371/journal.ppat.1004502 Source A related resource from which the described resource is derived PLoS Pathogens Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General), Immunologic diseases. Allergy Language A language of the resource EN