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Structure and inhibition of the SARS coronavirus envelope protein ion channel.
The envelope (E) protein from coronaviruses is a small polypeptide that contains at least one alpha-helical transmembrane domain. Absence, or inactivation, of E protein results in attenuated viruses, due to alterations in either virion morphology or…
Position: 7002 (34 views)
El fin de la frontera agrícola en Nicaragua y su impacto en el desarrollo nacional
El fin de la frontera agrícola en Nicaragua significa el fin de la disponibilidad de tierra para aumentar la producción agropecuaria extensiva, la cual, desde 1950 hasta ahora, es la principal base de la economía Nicaragüense. El presente estudio…
Position: 2350 (54 views)
[Lactate dehydrogenase, COVID-19 and mortality].
Position: 4359 (42 views)
Modeling and Forecasting the COVID-19 Temporal Spread in Greece: An Exploratory Approach based on Complex Network Defined Splines
Within the complex framework of anti-COVID-19 health management, where the criteria of diagnostic testing, the availability of public-health resources and services, and the applied anti-COVID-19 policies vary between countries, the reliability and…
Position: 13248 (25 views)
Activation of TRL-7 and Innate Immunity as an Efficient Method Against COVID-19 Pandemic: Imiquimod as a Potential Therapy
Position: 14996 (23 views)
Anticoagulation therapy in COVID-19: Is there a dose-dependent benefit?
Position: 15880 (22 views)
When there is a pandemic there is no time to waste: should we have hydroxychloroquine in our armoury against COVID-19 infected patients?
The current use of chloroquine and/or hydroxychloroquine, a drug currently used to treat autoimmune rheumatic diseases, in treating severe acute respiratory syndrome caused by coronavirus 2 (SARSCoV-2) or COVID-19-infected patients with pneumonia is…
Position: 3045 (49 views)
Online education and best practices for the development of a distance education program
This article discusses the benefits and challenges of online teaching and learning and details the process for creating a distance education program from the formation of a development team through the creation, implementation and evaluation of…
Position: 11508 (27 views)
Multisystem Inflammatory Syndrome in Children (MIS-C) associated with Kawasaki Disease in a three-year-old girl with SARS-CoV-2 infection
Kawasaki Disease (KD) is an acute and restrictive vasculitis. Studies have noted a viral association with the occurrence of this syndrome. This article reports a child with several severe inflammatory syndrome symptoms associated with COVID-19 and…
Position: 16702 (21 views)
Structure–Activity Relationships and Molecular Docking Analysis of Mcl-1 Targeting Renieramycin T Analogues in Patient-derived Lung Cancer Cells
Myeloid cell leukemia 1 (Mcl-1) and B-cell lymphoma 2 (Bcl-2) proteins are promising targets for cancer therapy. Here, we investigated the structure–activity relationships (SARs) and performed molecular docking analysis of renieramycin T (RT) and its…
Position: 12343 (26 views)