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                  <text>Dominio científico: Coronavirus</text>
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                <text>Increased physiological dead space in mechanically ventilated COVID-19 patients recovering from severe acute respiratory distress syndrome: a case report</text>
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                <text>Jingen Xia, Yingying Feng, Min Li, Xin Yu, Yi Zhang, Jun Duan, Qingyuan Zhan</text>
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                <text>Abstract Background An ongoing outbreak of coronavirus disease 2019 (COVID-19) is spreading globally. Recently, several articles have mentioned that the early acute respiratory distress syndrome (ARDS) caused by COVID-19 significantly differ from those of ARDS due to other causes. Actually, we newly observed that some mechanically ventilated COVID-19 patients recovering from severe ARDS (more than 14 days after invasive ventilation) often experienced evidently gradual increases in CO2 retention and minute ventilation. However, the underlying mechanics remain unclear. Case presentation To explain these pathophysiological features and discuss the ventilatory strategy during the late phase of severe ARDS in COVID-19 patients, we first used a metabolic module on a General Electric R860 ventilator (Engstrom Carestation; GE Healthcare, USA) to monitor parameters related to gas metabolism, lung mechanics and physiological dead space in two COVID-19 patients. We found that remarkably decreased ventilatory efficiency (e.g., the ratio of dead space to tidal volume 70–80%, arterial to end-tidal CO2 difference 18–23 mmHg and ventilatory ratio 3–4) and hypermetabolism (oxygen consumption 300–400 ml/min, CO2 elimination 200–300 ml/min) may explain why these patients experienced more severe respiratory distress and CO2 retention in the late phase of ARDS caused by COVID-19. Conclusion During the recovery period of ARDS among mechanically-ventilated COVID-19 patients, attention should be paid to the monitoring of physiological dead space and metabolism. Tidal volume (8–9 ml/kg) could be increased appropriately under the limited plateau pressure; however, barotrauma should still be kept in mind.</text>
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                <text>2020</text>
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                <text>Case report, acute respiratory distress syndrome, Coronavirus disease 2019, mechanical ventilation, Dead-space ventilation</text>
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                <text>10.1186/s12879-020-05360-5</text>
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                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Infectious and parasitic diseases</text>
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                <text>Increased post myocardial infarction complications in COVID-19 outbreak: Is it dilemma?</text>
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                <text>Azin Alizadehasl, Bahram Mohebbi, Shirin Habibi Khorasani</text>
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                <text>Journal of cardiovascular and thoracic research</text>
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                <text>Increased Risk of Acquisition of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) among a Cohort of COVID-19 Patients in a Teaching Hospital in Tuscany, Italy</text>
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                <text>Andrea  Davide Porretta, Angelo Baggiani, Guglielmo Arzilli, Virginia Casigliani, Tommaso Mariotti, Francesco Mariottini, Giuditta Scardina, Daniele Sironi, Michele Totaro, Simona Barnini, Gaetano  Pierpaolo Privitera</text>
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                <text>We describe the epidemiology of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) colonization/infection in a cohort of COVID-19 patients in an Italian teaching hospital. These patients had an increased risk of NDM-CRE acquisition versus the usual patients (75.9 vs. 25.3 cases/10,000 patient days). The co-infection significantly increased the duration of hospital stay (32.9 vs. 15.8 days).</text>
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                <text>surveillance, covid-19, New Delhi metallo-beta-lactamase, health care related infections</text>
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                <text>10.3390/pathogens9080635</text>
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                <text>Biotemas</text>
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                <text>Universidade Federal de Santa Catarina</text>
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                <text>M Bistoquet, F Galtier, G Marin, O Villard, R Ferreira, S Hermabessiere, A Montoya, E Jumas-Bilak, G-P Pageaux, O Dereure, G Chanques, K Klouche, D Morquin, J Reynes, V Le Moing, M-C Picot, E Tuaillon, A Makinson</text>
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                <text>Mario Rodríguez Rodríguez, Nerea Castro Quismondo, Denis Zafra Torres, Daniel Gil Alos, Rosa Ayala, Joaquín Martinez-Lopez</text>
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                <text>O Restaurante Escola Bistrô Eco Sol é um projeto de extensão desenvolvido na Incubadora de Tecnologias Sociais e Solidárias da Universidade Federal da Grande Dourados (ITESS/UFGD), em parceria com o Curso de Nutrição,junto a Assentados da Reforma Agrária e Quilombolas, oriundos de grupos de empreendedorismo, baseado nos princípios da Economia Solidária, que careciam de ações específicas no que tange a conhecimentos aplicados de Gastronomia, produção de refeições e gestão de serviços de alimentação, com garantia de segurança do consumidor e como possibilidade de geração de renda. O projeto beneficia, tanto esse público, quanto a comunidade acadêmica. Estruturado no tripé qualidade (higênico-sanitária, sensorial e nutricional), ambiência e custo, funciona desde outubro de 2014.Com serviço de almoço, utiliza alimentos da agricultura familiar, em sua maioria orgânicos, garantindo cinco cores de frutas e hortaliças ao dia, suco natural, sobremesas caseiras e um prato típico. No vínculo ensino-pesquisa, se incluem acadêmicos de Mestrado em Agronegócios e de Graduação em Nutrição. O esperado é que, ao final de dois anos,as empreendedoras estejam preparadas para implantar um serviço semelhante em suas comunidades, proporcionando geração de renda, inclusão social, disseminação dos princípios da Economia Solidária e desenvolvimento local sustentável.</text>
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                <text>O presente trabalho é um resultado de uma pesquisa sobre o mapeamento das Incubadoras Tecnossociais de Cooperativas Populares (ITCP) realizada no sul do Brasil, cujo objetivo é analisar a situação atual destas. A metodologia utilizada para a realização desta pesquisa foi o método da revisão bibliográfica integrativa seguida pelos dados do mapeamento das incubadoras, construção e qualificação de um questionário quantitativo. O questionário foi aplicado em incubadoras da região sul do Brasil onde foram analisados e processadas as respostas das ITCPs do Rio Grande do Sul em uma Planilha Calc do software livre da LibreOffice. Com a pesquisa, observou-se que os empreendimentos incubados nas ITCPs enfrentam dificuldades no início da incubação, principalmente quanto aos custos de financiamento. Constatou-se também que muitos empreendimentos incubados não possuem legalização de suas atividades. Pôde-se observar que as principais linha de atuação dos empreendimentos incubados são a Economia Solidária, Cooperativas e Agricultura Familiar. Os dados obtidos com a presente pesquisa são de grande relevância para avaliar a situação atual das ITCPs do Rio Grande do Sul, porém é necessário um aprofundamento em futuras pesquisas para entender qualitativamente a situação e como esta pode ser melhorada.  Agradecimento especial ao CNPq, agente financiador desta pesquisa.</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="152619">
                <text>2016</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="152620">
                <text>Extensão Universitária, Incubadoras, Revisão Integrativa</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="152621">
                <text>10.5007/1983-4535.2016v9n4p189</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="152622">
                <text>Revista Gestão Universitária na América Latina</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="152623">
                <text>Universidade Federal de Santa Catarina</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="152624">
                <text>Special aspects of education, Education (General)</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="46">
            <name>Relation</name>
            <description>A related resource</description>
            <elementTextContainer>
              <elementText elementTextId="152625">
                <text>&lt;a href="https://periodicos.ufsc.br/index.php/gual/article/view/48286" target="_blank" rel="noreferrer noopener"&gt;https://periodicos.ufsc.br/index.php/gual/article/view/48286&lt;/a&gt;</text>
              </elementText>
            </elementTextContainer>
          </element>
        </elementContainer>
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