1092 10 20655 https://www.socictopen.socict.org/files/original/923a6ffd492795c6983f4aad2fe25ef6.pdf beb7066326b33a3a5404c8b0c04765de Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Potential of DNA Intercalating Alkaloids and Other Plant Secondary Metabolites against SARS-CoV-2 Causing COVID-19 Creator An entity primarily responsible for making the resource Michael Wink Description An account of the resource Many plants produce secondary metabolites (PSMs) with antiviral activities. Among the antiviral PSMs, lipophilic terpenoids in essential oils can disturb the lipid envelope of viruses. Phenols and polyphenols (flavonoids, rosmarinic acid and tannins) attack viral proteins present in the viral membrane or inside the virus particle. Both phenolics and essential oils are active against free viral particles but not—or to a lesser degree—after a virus has entered a host cell. Another group of PSMs is directed against DNA or RNA. These are DNA intercalators such as sanguinarine, berberine, emetine and other isoquinoline alkaloids, ß-carboline, and quinoline alkaloids such as quinine, cinchonine, dictamine and skimmianine. The DNA intercalators stabilize double-stranded nucleic acids and inhibit the replication, transcription, and translation of genetic material. These alkaloids can inhibit viral development and viral replication in cells, as shown for SARS-CoV-1 and other viruses. Since chloroquine (which is also a DNA intercalator and a chemical derivative of the alkaloid quinine) is apparently clinically helpful against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, it is assumed that intercalating alkaloids, or the medicinal plants producing them, may be interesting candidates for the development of new antiviral drugs for the treatment of coronavirus disease 2019 (COVID-19). Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource polyphenols, essential oil, Plant secondary metabolites, intercalating alkaloids, inhibition of polymerases, inhibition of protein biosynthesis Identifier An unambiguous reference to the resource within a given context 10.3390/d12050175 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General) https://www.socictopen.socict.org/files/original/0b0c7aa9138650d126f3cb7daa546ed5.pdf ce4a9c27c8289fb3b1976242a893b132 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Propagation, Inactivation, and Safety Testing of SARS-CoV-2 Creator An entity primarily responsible for making the resource Alexander S. Jureka, Jesus A. Silvas, Christopher F. Basler Description An account of the resource In late 2019, a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, the capital of the Chinese province Hubei. Since then, SARS-CoV-2 has been responsible for a worldwide pandemic resulting in over 4 million infections and over 250,000 deaths. The pandemic has instigated widespread research related to SARS-CoV-2 and the disease that it causes, COVID-19. Research into this new virus will be facilitated by the availability of clearly described and effective procedures that enable the propagation and quantification of infectious virus. As work with the virus is recommended to be performed at biosafety level 3, validated methods to effectively inactivate the virus to enable the safe study of RNA, DNA, and protein from infected cells are also needed. Here, we report methods used to grow SARS-CoV-2 in multiple cell lines and to measure virus infectivity by plaque assay using either agarose or microcrystalline cellulose as an overlay as well as a SARS-CoV-2 specific focus forming assay. We also demonstrate effective inactivation by TRIzol, 10% neutral buffered formalin, beta propiolactone, and heat. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource coronavirus, virus, virology, SARS-CoV-2, plaque assay, inactivation Identifier An unambiguous reference to the resource within a given context 10.3390/v12060622 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology https://www.socictopen.socict.org/files/original/f7679ecdea819e82960e28f1f3a3bab5.pdf 64afcd43c12498bbd3249c8a3181b69c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Changes in Diet, Sleep, and Physical Activity Are Associated With Differences in Negative Mood During COVID-19 Lockdown Creator An entity primarily responsible for making the resource Joanne Ingram, Greg Maciejewski, Christopher J. Hand Description An account of the resource The United Kingdom and Scottish governments instigated a societal lockdown in response to the COVID-19 pandemic. Subsequently, many experienced substantial lifestyle changes alongside the stresses of potentially catching the virus or experiencing bereavement. Stressful situations and poorer health behaviors (e.g., higher alcohol consumption, unhealthy diet, poorer sleep quality, physical inactivity) are frequently linked to poor mental health. Our objective was to examine changes in health behaviors and their relationship with negative mood during COVID-19 lockdown. We also considered associations between health behaviors and socio-demographic differences and COVID-19-induced changes. 399 participants completed a questionnaire asking about their personal situation and health behaviors during lockdown as well as a negative mood scale. The significance threshold for all analyses was α = 0.05. Poorer diet was linked to more-negative mood, and to changes to working status. Poorer sleep quality was linked with more-negative mood, and with ‘shielding’ from the virus. Being less physically active was related to more-negative mood and student status, whereas being more physically active was linked to having or suspecting COVID-19 infection within the household. Increased alcohol consumption was linked to living with children, but not to negative mood. Changes to diet, sleep quality, and physical activity related to differences in negative mood during COVID-19 lockdown. This study adds to reports on poor mental health during lockdown and identifies lifestyle restrictions and changes to health behaviors which may, to some extent, be responsible for higher negative mood. Our data suggests that it is advisable to maintain or improve health behaviors during pandemic-associated restrictions. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, lockdown, physical activity, Sleep, diet, alcohol Identifier An unambiguous reference to the resource within a given context 10.3389/fpsyg.2020.588604 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Psychology https://www.socictopen.socict.org/files/original/8f66f4bfea93befd9e0542861d0d163b.pdf 60ea0e3ca116ea89dc484c043d4f7d93 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A University Students&rsquo; Response to an Article on the Psychological Impacts of COVID-19 Pandemic Among University Students in Bench-Sheko Zone [Letter] Creator An entity primarily responsible for making the resource Malik SI, Ahmed M, Khattab N Description An account of the resource Saba-Ikhlas Malik, Muna Ahmed, Nour Khattab Faculty of Medicine, St George&rsquo;s University of London, London, UKCorrespondence: Saba-Ikhlas MalikFaculty of Medicine, St George&rsquo;s University of London, London, UKEmail m1400090@sgul.ac.uk As university students, we read with great interest the article by Aylie et al about&nbsp;the effect of the COVID-19 pandemic on university student mental health. The&nbsp;article highlighted that there has been an increase in&nbsp; depression, anxiety and stress&nbsp;levels and the need for governmental organisations to integrate psychological&nbsp;support into upcoming initiatives.1 &nbsp; View the original paper by&nbsp;Aylie and colleagues Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Depression anxiety stress Source A related resource from which the described resource is derived Biotemas Publisher An entity responsible for making the resource available Universidade Federal de Santa Catarina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Psychology, Industrial psychology https://www.socictopen.socict.org/files/original/58ff4d77bf035820c82cf5ca4171706a.pdf f8ac21fffea67398f39cf21daa708ba1 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Tempos de re-invenção, re-criação e re-encontros Creator An entity primarily responsible for making the resource Sirlei Antoninha Kroth Gaspareto, Zenaide Collet Description An account of the resource Este texto busca fazer reflexões sobre o momento atual caracterizado pela pandemia da Covid-19. Evidenciamos, como ponto de partida, memórias de uma experiência fundamentada na Teologia da Libertação, a qual influenciou o surgimento dos Movimentos Sociais Populares, principalmente na região oeste de Santa Catarina. Realiza-se a análise de repetidas crises originadas no seio do sistema capitalista que, em sua perversidade, re-cria-se de múltiplas maneiras e se faz permanente na travessia de nossas vidas. E, em meio à pandemia, destaca-se a sofisticação tecnológica, os “paradigmas tecnocráticos” que, no dizer do Papa Francisco, orientam muitos governos ao redor do mundo, mas “não são suficientes para abordar esta crise, nem os outros grandes problemas da humanidade”. O texto menciona o importante papel das mulheres no enfrentamento à pandemia. Acrescenta-se à reflexão elementos do referencial bíblico cristão que fundamentam e provocam o questionamento: a que re-invenção, re-criação, re-encontros nos referimos? O propósito é refletir sobre a necessidade permanente de aprimorar os elementos narrativos e críticos considerados fundamentais enquanto perspectiva humana de continuidade da vida. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource pandemia, crise, Escolhas, Reinvenção Identifier An unambiguous reference to the resource within a given context 10.14393/REP-2020-55650 Source A related resource from which the described resource is derived Revista de Educação Popular Publisher An entity responsible for making the resource available Editora da Universidade Federal de Uberlândia Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Social Sciences, Labor in politics. Political activity of the working class https://www.socictopen.socict.org/files/original/b914981c8a16fcfee2f16b36d85fe50d.pdf f697004bfb505bc6157a29b260b39c5d Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Clinical Characteristics and Predictors of Mortality in Patients with COVID-19 Infection Outside Intensive Care Creator An entity primarily responsible for making the resource Moledina SM, Maini AA, Gargan A, Harland W, Jenney H, Phillips G, Thomas K, Chauhan D, Fertleman M Description An account of the resource Saadiq M Moledina,* Alexander A Maini,* Alice Gargan, William Harland, Heloise Jenney, Georgina Phillips, Kate Thomas, Devkishan Chauhan, Michael Fertleman From the Cutrale Perioperative &amp; Ageing Group, St Mary&rsquo;s Hospital, Imperial College London, London, UK*These authors contributed equally to this workCorrespondence: Saadiq M MoledinaSt Mary&rsquo;s Hospital, Imperial College London, Praed Street, Paddington, London W2 1NY, UKTel +44 02033126666Email smoledina1@doctors.org.ukBackground/Introduction: The coronavirus disease 2019 (COVID-19) pandemic has affected all aspects of inpatient hospital medicine with patients admitted from level 1 (general medical wards) to level 3 (intensive care). Often, there are subtle physiological differences in these cohorts of patients. In particular, in intensive care, patients tend to be younger and have increased disease severity. Data, to date, has combined outcomes from medical and intensive care cohorts, or looked exclusively at intensive care. We looked solely at the level 1 (medical) cohort to identify their clinical characteristics and predictors of outcome.Patients and Methods: This was a retrospective study of adult patients admitted to a central London teaching hospital with a diagnosis of COVID-19 from 23rd March to 7th April 2020 identified from the hospital electronic database. Any patients who required level 2 or 3 care were excluded.Results: A total of 229 patients were included for analysis. Increased age and frailty scores were associated with increased 30-day mortality. Reduced renal function and elevated troponin blood levels are also associated with poor outcome. Baseline observations showed that increased oxygen requirement was predictive for mortality. A trend of increased mortality with lower diastolic blood pressure was noted. Lymphopenia was not shown to be related to mortality.Conclusion: Urea and creatinine are the best predictors of mortality in the level 1 cohort. Unlike previous intensive care data, lymphopenia is not predictive of mortality. We suggest that these factors be considered when prognosticating and for resource allocation for the treatment and escalation of care for patients with COVID-19 infection.Keywords: COVID-19, mortality, frailty, ICU, renal dysfunction, lymphopenia Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource mortality, ICU, covid-19, Lymphopenia, Frailty, Renal dysfunction Source A related resource from which the described resource is derived Biotemas Publisher An entity responsible for making the resource available Universidade Federal de Santa Catarina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine (General) https://www.socictopen.socict.org/files/original/87e043448f2acae180489ce08fc9943b.pdf 4c070ceafba9845a84929b9a578d160c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource SARS-CoV-2 outbreak in immune-mediated inflammatory diseases: the Euro-COVIMID multicentre cross-sectional study. Creator An entity primarily responsible for making the resource David Saadoun, Matheus Vieira, Mathieu Vautier, Xenofon Baraliakos, Ioana Andreica, José A P da Silva, Marlene Sousa, Mariana Luis, Nikita Khmelinskii, José María Alvaro Gracía, Isabel Castrejon, Juan Carlos Nieto Gonzalez, Carlo Alberto Scirè, Ettore Silvagni, Alessandra Bortoluzzi, Henry Penn, Shahir Hamdulay, Pedro M Machado, Bruno Fautrel, Patrice Cacoub, Matthieu Resche-Rigon, Laure Gossec Description An account of the resource The COVID-19 pandemic has raised numerous questions among patients with immune-mediated inflammatory diseases regarding potential reciprocal effects of COVID-19 and their underlying disease, and potential effects of immunomodulatory therapy on outcomes related to COVID-19. The seroprevalence of SARS-CoV-2 and factors associated with symptomatic COVID-19 in patients with immune-mediated inflammatory diseases are still unclear. The Euro-COVIMID study aimed to determine the serological and clinical prevalence of COVID-19 among patients with immune-mediated inflammatory diseases, as well as factors associated with COVID-19 occurrence and the impact of the pandemic in its management. In this multicentre cross-sectional study, patients aged 18 years or older with a clinical diagnosis of rheumatoid arthritis, axial spondyloarthritis, systemic lupus erythematosus, Sjögren's syndrome, or giant cell arteritis were recruited from six tertiary referral centres in France, Germany, Italy, Portugal, Spain, and the UK. Demographics, comorbidities, treatments, and recent disease flares, as well as information on COVID-19 symptoms, were collected through a questionnaire completed by participants. SARS-CoV-2 serology was systematically tested. The main outcome was the serological and clinical prevalence of COVID-19. Factors associated with symptomatic COVID-19 were assessed by multivariable logistic regression, and incidence of recent disease flares, changes in treatments for underlying disease, and the reasons for treatment changes were also assessed. This study is registered with ClinicalTrials.gov, NCT04397237. Between June 7 and Dec 8, 2020, 3136 patients with an immune-mediated inflammatory disease answered the questionnaire. 3028 patients (median age 58 years [IQR 46-67]; 2239 [73·9%] women and 789 [26·1%] men) with symptomatic COVID-19, serological data, or both were included in analyses. SARS-CoV-2 antibodies were detected in 166 (5·5% [95% CI 4·7-6·4]) of 3018 patients who had serology tests. Symptomatic COVID-19 occurred in 122 (4·0% [95% CI 3·4-4·8]) of 3028 patients, of whom 24 (19·7%) were admitted to hospital and four (3·3%) died. Factors associated with symptomatic COVID-19 were higher concentrations of C-reactive protein (odds ratio 1·18, 95% CI 1·05-1·33; p=0·0063), and higher numbers of recent disease flares (1·27, 1·02-1·58; p=0·030), whereas use of biological therapy was associated with reduced risk (0·51, 0·32-0·82; p=0·0057). At least one disease flare occurred in 654 (21·6%) of 3028 patients. Over the study period, 519 (20·6%) of 2514 patients had treatment changes, of which 125 (24·1%) were due to the pandemic. This study provides key insights into the epidemiology and risk factors of COVID-19 among patients with immune-mediated inflammatory diseases. Overall, immunosuppressants do not seem to be deleterious in this scenario, and the control of inflammatory activity seems to be key when facing the pandemic. Pfizer, Sanofi, Amgen, Galapagos, and Lilly. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Identifier An unambiguous reference to the resource within a given context 10.1016/S2665-9913(21)00112-0 Source A related resource from which the described resource is derived The Lancet. Rheumatology https://www.socictopen.socict.org/files/original/7bfc5f4e25f561e2012c121e62b2901d.pdf 443e4f6b1b76d8dea904081eecfde06d Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The Association of Subacute Thyroiditis with COVID-19: a Systematic Review. Creator An entity primarily responsible for making the resource Muhammad Aemaz Ur Rehman, Hareem Farooq, Muhammad Mohsin Ali, Muhammad Ebaad Ur Rehman, Qudsia Anwar Dar, Awab Hussain Description An account of the resource The multisystem effects of SARS-CoV-2 encompass the thyroid gland as well. Emerging evidence suggests that SARS-CoV-2 can act as a trigger for subacute thyroiditis (SAT). We conducted a systematic literature search using PubMed/Medline and Google Scholar to identify cases of subacute thyroiditis associated with COVID-19 and evaluated patient-level demographics, major clinical features, laboratory findings and outcomes. In the 21 cases that we reviewed, the mean age of patients was 40.0 ± 11.3 years with a greater female preponderance (71.4%). Mean number days between the start of COVID-19 illness and the appearance of SAT symptoms were 25.2 ± 10.1. Five patients were confirmed to have ongoing COVID-19, whereas the infection had resolved in 16 patients before onset of SAT symptoms. Fever and neck pain were the most common presenting complaints (81%). Ninety-four percent of patients reported some type of hyperthyroid symptoms, while the labs in all 21 patients (100%) confirmed this with low TSH and high T3 or T4. Inflammatory markers were elevated in all cases that reported ESR and CRP. All 21 cases (100%) had ultrasound findings suggestive of SAT. Steroids and anti-inflammatory drugs were the mainstay of treatment, and all patients reported resolution of symptoms; however, 5 patients (23.8%) were reported to have a hypothyroid illness on follow-up. Large-scale studies are needed for a better understanding of the underlying pathogenic mechanisms, but current evidence suggests that clinicians need to recognize the possibility of SAT both in ongoing and resolved COVID-19 infection to optimize patient care. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource covid-19, SARS-CoV-2, subacute thyroiditis, Viral thyroiditis, De Quervain’s thyroiditis Identifier An unambiguous reference to the resource within a given context 10.1007/s42399-021-00912-5 Source A related resource from which the described resource is derived SN comprehensive clinical medicine https://www.socictopen.socict.org/files/original/28dd4fa7508135b97e636633e1513b70.pdf a11005f5a64d89c2dc77df68c28f1b87 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource High incidence of stroke and mortality in pediatric critical care patients with COVID-19 in Peru. Creator An entity primarily responsible for making the resource Alvaro Coronado Munoz, Jaime Tasayco, Willy Morales, Luis Moreno, David Zorrilla, Angie Stapleton, Patricia Pajuelo, Giuliana Reyes, Matilde Estupiñan, Ricardo Seminario, Manuel Ortiz, Jesús Domínguez Description An account of the resource Pediatric critical care patients with COVID-19 treated in Peru have higher mortality than those previously reported from other countries. Pediatric providers have reported a high number of patients without comorbidities presenting with hemorrhagic strokes associated with COVID-19. We present a study analyzing the factors associated with mortality in this setting. Prospective case-control study that included patients <17 years old admitted to a pediatric critical care unit with a positive test confirming COVID-19. The primary outcome was mortality. Fisher's exact test and the Mann-Whitney U test were used for the analysis. Forty-seven patients were admitted to critical care. The mortality of our study is 21.3%. The mortality of patients with neurological presentation was 45.5%, which was significantly higher than the mortality of acute COVID-19 (26.7%) and MIS-C (4.8%), p 0.18. Other risk factors for mortality in our cohort were strokes and comorbidities. Only one patient presenting with hemorrhagic stroke had an undiagnosed comorbidity. Cerebrovascular events associated with COVID-19 in pediatric patients, including infants, must be recognized as one of the more severe presentations of this infection in pediatric patients. Pediatric patients with COVID-19 can present with hemorrhagic and ischemic strokes on presentation. Neurological presentation in pediatric patients with COVID-19 has high mortality. Mortality of pediatric patients with COVID-19 is associated with comorbidities. Pediatric presentation and outcomes of COVID-19 in different regions can be novel to previously described. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Identifier An unambiguous reference to the resource within a given context 10.1038/s41390-021-01547-x Source A related resource from which the described resource is derived Pediatric research https://www.socictopen.socict.org/files/original/079ba742f5047ca40a4eb527108c8abf.pdf eba047ae0af25a6afc2e293f02037003 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource COVID-19 vaccine exclusion based on legal residence is unwise and unethical. Creator An entity primarily responsible for making the resource Lisa M Lee, Abigail E Lowe, Matthew K Wynia Date A point or period of time associated with an event in the lifecycle of the resource 2021 Identifier An unambiguous reference to the resource within a given context 10.1057/s41271-021-00286-x Source A related resource from which the described resource is derived Journal of public health policy