1101 10 20655 https://www.socictopen.socict.org/files/original/963857253c869931bad85b1886374691.pdf 98f95bf93b423d85a1e06191c3d40eff Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The sharing of research data facing the COVID-19 pandemic. Creator An entity primarily responsible for making the resource Rut Lucas-Dominguez, Adolfo Alonso-Arroyo, Antonio Vidal-Infer, Rafael Aleixandre-Benavent Description An account of the resource During the previous Ebola and Zika outbreaks, researchers shared their data, allowing many published epidemiological studies to be produced only from open research data, to speed up investigations and control of these infections. This study aims to evaluate the dissemination of the COVID-19 research data underlying scientific publications. Analysis of COVID-19 publications from December 1, 2019, to April 30, 2020, was conducted through the PubMed Central repository to evaluate the research data available through its publication as supplementary material or deposited in repositories. The PubMed Central search generated 5,905 records, of which 804 papers included complementary research data, especially as supplementary material (77.4%). The most productive journals were The New England Journal of Medicine, The Lancet and The Lancet Infectious Diseases, the most frequent keyword was pneumonia, and the most used repositories were GitHub and GenBank. An expected growth in the number of published articles following the course of the pandemics is confirmed in this work, while the underlying research data are only 13.6%. It can be deduced that data sharing is not a common practice, even in health emergencies, such as the present one. High-impact generalist journals have accounted for a large share of global publishing. The topics most often covered are related to epidemiological and public health concepts, genetics, virology and respiratory diseases, such as pneumonia. However, it is essential to interpret these data with caution following the evolution of publications and their funding in the coming months. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource covid-19, data-sharing, supplementary material, repository, PubMed central Identifier An unambiguous reference to the resource within a given context 10.1007/s11192-021-03971-6 Source A related resource from which the described resource is derived Scientometrics https://www.socictopen.socict.org/files/original/ff363c07d727ee861d38a478a888a8fd.pdf 3e3bc05669ca672c6d46223804d43c40 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Effectiveness of anaesthesia ventilator use for mechanical ventilation in critically ill patients during the COVID-19 pandemic. Creator An entity primarily responsible for making the resource Aurélie Gouel-Cheron, Yoann Elmaleh, Camille Couffignal, Elie Kantor, Simon Meslin, Anaïs Caillard, Arthur Salome, Sophie Hamada, Bernard Cholley, Alexandre Mebazaa, Dan Longrois, Jean-Louis Bourgain, Valérie Billard, Frédérique Servin, Philippe Montravers Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource covid-19, acute respiratory distress syndrome, mechanical ventilation, anaesthesia ventilator, heat and moisture exchange filter Identifier An unambiguous reference to the resource within a given context 10.1016/j.bja.2021.04.001 Source A related resource from which the described resource is derived British journal of anaesthesia https://www.socictopen.socict.org/files/original/25d9061488257e0709ad40d74a90321e.pdf 8e90a9c9b0c2b66713594bb2bf2b02f8 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus disease 2019 (COVID-19): Faith healing or science? An old-time problem. Creator An entity primarily responsible for making the resource Marios Papadakis Date A point or period of time associated with an event in the lifecycle of the resource 2021 Identifier An unambiguous reference to the resource within a given context 10.1017/ice.2021.198 Source A related resource from which the described resource is derived Infection control and hospital epidemiology https://www.socictopen.socict.org/files/original/7f868b17d9c56f4ae1e532fed351271e.pdf 6e35a4b297b349daac5d19ed0b5f6449 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Bacterial coinfections in coronavirus disease 2019. Creator An entity primarily responsible for making the resource Lars F Westblade, Matthew S Simon, Michael J Satlin Description An account of the resource Bacterial coinfections increase the severity of respiratory viral infections and were frequent causes of mortality in influenza pandemics but have not been well characterized in patients with coronavirus disease 2019 (COVID-19). The aim of this review was to identify the frequency and microbial etiologies of bacterial coinfections that are present upon admission to the hospital and that occur during hospitalization for COVID-19. We found that bacterial coinfections were present in <4% of patients upon admission and the yield of routine diagnostic tests for pneumonia was low. When bacterial coinfections did occur, Staphylococcus aureus, Streptococcus pneumoniae, and Haemophilus influenzae were the most common pathogens and atypical bacteria were rare. Although uncommon upon admission, bacterial infections frequently occurred in patients with prolonged hospitalization, and Pseudomonas aeruginosa, Klebsiella spp., and S. aureus were common pathogens. Antibacterial therapy and diagnostic testing for bacterial infections are unnecessary upon admission in most patients hospitalized with COVID-19, but clinicians should be vigilant for nosocomial bacterial infections. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource hospital-acquired infections, coronavirus disease 2019 (covid-19), severe acute respiratory syndrome coronavirus 2 (sars-cov-2), multidrug resistance (MDR), bacterial coinfection Identifier An unambiguous reference to the resource within a given context 10.1016/j.tim.2021.03.018 Source A related resource from which the described resource is derived Trends in microbiology https://www.socictopen.socict.org/files/original/14090ac0a128053b74fedf69ab270576.pdf e73494539af876705be6c06f58e3a480 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource In silico screening of potent bioactive compounds from honeybee products against COVID-19 target enzymes. Creator An entity primarily responsible for making the resource Mohamed M. Abdel-DAIM, Moataz A Shaldam, Galal Yahya, Nashwa H Mohamed, Yahya Al Naggar Description An account of the resource After the early advent of the Coronavirus Disease 2019 (COVID-19) pandemic, myriads of FDA-approved drugs have been massively repurposed for COVID-19 treatment based on molecular docking against selected protein targets that play fundamental roles in the replication cycle of the novel coronavirus. Honeybee products are well known of their nutritional values and medicinal effects. Bee products contain bioactive compounds in the form of a collection of phenolic acids, flavonoids, and terpenes of natural origin that display wide spectrum antiviral effects. We revealed by molecular docking the profound binding affinity of 14 selected phenolics and terpenes present in honey and propolis (bees glue) against the main protease (Mpro) and RNA-dependent RNA polymerase (RdRp) enzymes of the novel SARS-CoV-2 virus (the causative agent of COVID-19) using AutoDock Vina software. Of these compounds, p-coumaric acid, ellagic acid, kaempferol, and quercetin have the strongest interaction with the SARS-CoV-2 target enzymes, and it may be considered an effective COVID-19 inhibitor. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource molecular docking, covid-19, drug repurposing, Phenolic compounds, Natural products, Honeybee products Identifier An unambiguous reference to the resource within a given context 10.1007/s11356-021-14195-9 Source A related resource from which the described resource is derived Environmental science and pollution research international https://www.socictopen.socict.org/files/original/1234a33178cddb84c7e907d5faadb9fb.pdf 1b4165ea0e8380fbd80f2d88fc6b7427 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Demyelination as a result of an immune response in patients with COVID-19. Creator An entity primarily responsible for making the resource Zahra Shabani Description An account of the resource The coronavirus disease of 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus-2 (SARS CoV-2), that already appeared as a global pandemic. Presentation of the disease often includes upper respiratory symptoms like dry cough, dyspnea, chest pain, and rhinorrhea that can develop to respiratory failure, needing intubation. Furthermore, the occurrence of acute and subacute neurological manifestations such as stroke, encephalitis, headache, and seizures are frequently stated in patients with COVID-19. One of the reported neurological complications of severe COVID-19 is the demolition of the myelin sheath. Indeed, the complex immunological dysfunction provides a substrate for the development of demyelination. Nevertheless, few published reports in the literature describe demyelination in subjects with COVID-19. In this short narrative review, we discuss probable pathological mechanisms that may trigger demyelination in patients with SARS-CoV-2 infection and summarize the clinical evidence, confirming SARS-CoV-2 condition as a risk factor for the destruction of myelin. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource covid-19, SARS‐CoV‐2, immune response, demyelination, multiple sclerosis Identifier An unambiguous reference to the resource within a given context 10.1007/s13760-021-01691-5 Source A related resource from which the described resource is derived Acta neurologica Belgica https://www.socictopen.socict.org/files/original/ba6d32ec7b1fa2119ed914bf23eadc5e.pdf 24c145a4e652ab4f2b1595f091c96bde Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Human gene polymorphisms and their possible impact on the clinical outcome of SARS-CoV-2 infection. Creator An entity primarily responsible for making the resource Seyed Mohammad Ali Hashemi, Marijn Thijssen, Seyed Younes Hosseini, Alijan Tabarraei, Mahmoud Reza Pourkarim, Jamal Sarvari Description An account of the resource The SARS-CoV-2 pandemic has become one of the most serious health concerns globally. Although multiple vaccines have recently been approved for the prevention of coronavirus disease 2019 (COVID-19), an effective treatment is still lacking. Our knowledge of the pathogenicity of this virus is still incomplete. Studies have revealed that viral factors such as the viral load, duration of exposure to the virus, and viral mutations are important variables in COVID-19 outcome. Furthermore, host factors, including age, health condition, co-morbidities, and genetic background, might also be involved in clinical manifestations and infection outcome. This review focuses on the importance of variations in the host genetic background and pathogenesis of SARS-CoV-2. We will discuss the significance of polymorphisms in the ACE-2, TMPRSS2, vitamin D receptor, vitamin D binding protein, CD147, glucose-regulated protein 78 kDa, dipeptidyl peptidase-4 (DPP4), neuropilin-1, heme oxygenase, apolipoprotein L1, vitamin K epoxide reductase complex 1 (VKORC1), and immune system genes for the clinical outcome of COVID-19. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Identifier An unambiguous reference to the resource within a given context 10.1007/s00705-021-05070-6 Source A related resource from which the described resource is derived Archives of virology https://www.socictopen.socict.org/files/original/4867cba13b4361b247e16db667a77886.pdf 0aa7e77911f466ae29648a8388f3503a Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Quantification of Neurological Blood-Based Biomarkers in Critically Ill Patients With Coronavirus Disease 2019. Creator An entity primarily responsible for making the resource Ryan L Hoiland, Sonny Thiara, Denise Foster, Jennifer Cooper, Sophie Stukas, Nicholas A Fergusson, Anish Mitra, Jon A Stoessl, William J Panenka, Mypinder S Sekhon, Cheryl L Wellington Description An account of the resource To provide an objective characterization of acute neurologic injury in critically ill patients with coronavirus disease 2019. Prospective observational study. Demographics, comorbidities, and daily clinical physiologic and laboratory data were collected. Plasma levels of neurofilament-light chain, total tau, ubiquitin carboxy-terminal hydrolase L1, and glial fibrillary acidic protein were measured. The primary neurologic outcome was delirium defined by the Intensive Care Delirium Screening Checklist (scale 1-8). Associations among plasma biomarkers, respiratory failure, and inflammation were analyzed. Multicenter study in ICUs. Critically ill patients with respiratory failure, with coronavirus disease 2019, or without (ICU control). A total of 27 patients with coronavirus disease 2019 and 19 ICU controls were enrolled. Compared with ICU controls with pneumonia of other etiology, patients with coronavirus disease 2019 had significantly higher glial fibrillary acidic protein (272 pg/mL [150-555 pg/mL] vs 118 pg/mL [78.5-168 pg/mL]; p = 0.0009). In coronavirus disease 2019 patients, glial fibrillary acidic protein (rho = 0.5115, p = 0.0064), ubiquitin carboxy-terminal hydrolase L1 (rho = 0.4056, p = 0.0358), and neurofilament-light chain (rho = 0.6223, p = 0.0005) positively correlated with Intensive Care Delirium Screening Checklist score and were increased in patients with delirium (Intensive Care Delirium Screening Checklist ≥ 4) in the coronavirus disease 2019 group but not in ICU controls. There were no associations between the measures of respiratory function or cytokines with glial fibrillary acidic protein, total tau, ubiquitin carboxy-terminal hydrolase L1, or neurofilament-light chain levels in patients with coronavirus disease 2019. Plasma glial fibrillary acidic protein is two-fold higher in critically ill patients with coronavirus disease 2019 compared with ICU controls. Higher levels of glial fibrillary acidic protein, ubiquitin carboxy-terminal hydrolase L1, and neurofilament-light chain associate with delirium in patients with coronavirus disease 2019. Elevated plasma glial fibrillary acidic protein, ubiquitin carboxy-terminal hydrolase L1, and neurofilament-light chain are independent of respiratory function and peripheral cytokines. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Delirium, Coronavirus disease 2019, severe acute respiratory syndrome coronavirus 2, glial fibrillary acidic protein, neurofilament-light Identifier An unambiguous reference to the resource within a given context 10.1097/CCE.0000000000000238 Source A related resource from which the described resource is derived Critical care explorations https://www.socictopen.socict.org/files/original/1db7e99d02e3536a254a3e6fd91ad564.pdf 6a8c9969d73e1ebbd60b2bf3a3485932 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Modelling studies reveal the importance of the C-terminal inter motif loop of NSP1 as a promising target site for drug discovery and screening of potential phytochemicals to combat SARS-CoV-2. Creator An entity primarily responsible for making the resource Dhamodharan Prabhu, Sundaraj Rajamanikandan, Muthusamy Sureshan, Jeyaraman Jeyakanthan, Kadhirvel Saraboji Description An account of the resource COVID-19 pandemic causative SARS-CoV-2 coronavirus is still rapid in progression and transmission even after a year. Understanding the viral transmission and impeding the replication process within human cells are considered as the vital point to control and overcome COVID-19 infection. Non-structural Protein 1, one among the proteins initially produced upon viral entry into human cells, instantly binds with the human ribosome and inhibit the host translation process by preventing the mRNA attachment. However, the formation of NSP1 bound Ribosome complex does not affect the viral replication process. NSP1 plays an indispensable role in modulating the host gene expression and completely steals the host cellular machinery. The full-length structure of NSP1 is essential for the activity in the host cell and importantly the loop connecting N and C-terminal domains are reported to play a role in ribosome binding. Due to the unavailability of the experimentally determined full-length structure of NSP1, we have modelled the complete structure using comparative modelling and the stability and conformational behaviour of the modelled structure was evaluated through molecular dynamics simulation. Interestingly, the present study reveals the significance of the inter motif loop to serves as a potential binding site for drug discovery experiments. Further, we have screened the phytochemicals from medicinal plant sources since they were used for several hundred years that minimizes the traditional drug development time. Among the 5638 phytochemicals screened against the functionally associated binding site of NSP1, the best five phytochemicals shown high docking score of -9.63 to -8.75 kcal/mol were further evaluated through molecular dynamics simulations to understand the binding affinity and stability of the complex. Prime MM-GBSA analysis gave the relative binding free energies for the top five compounds (dihydromyricetin, 10-demethylcephaeline, dihydroquercetin, pseudolycorine and tricetin) in the range of -45.17 kcal/mol to -37.23 kcal/mol, indicating its binding efficacy in the predicted binding site of NSP1. The density functional theory calculations were performed for the selected five phytochemicals to determine the complex stability and chemical reactivity. Thus, the identified phytochemicals could further be used as effective anti-viral agents to overcome COVID-19 and as well as several other viral infections. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource covid-19, virtual screening, Nonstructural protein 1, antiviral molecules, β-CoV Identifier An unambiguous reference to the resource within a given context 10.1016/j.jmgm.2021.107920 Source A related resource from which the described resource is derived Journal of molecular graphics & modelling https://www.socictopen.socict.org/files/original/58f4137a00304b9eecf5d567ee643e32.pdf 9a0c70d644c22b9285ce6584ce00634d Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Pneumoperitoneum in a COVID-19 Patient Due to the Macklin Effect. Creator An entity primarily responsible for making the resource Ramon Vidrio Duarte, Eduardo Vidrio Duarte, Juan Gutierrez Ochoa, Maria Camila Gaviria Leiva, Joaquin A Pimentel-Hayashi Description An account of the resource A 63-year-old male with coronavirus disease 2019 (COVID-19) pneumonia presented to the emergency department, supplementary oxygen is delivered via nasal cannula, and invasive ventilation was not needed; there was significant pneumoperitoneum on radiologic control. After a meticulous examination of the thoracic tomography, there were some linear air collections adjacent to the bronchovascular sheaths, indicative of the Macklin effect, without abdominal alterations, and the patient remained stable; therefore, we did not perform a surgical procedure, and the pneumoperitoneum reabsorbed spontaneously on radiologic control. The pulmonary origin of pneumoperitoneum is unusual and is associated with mechanical ventilation and alveolar leak; the air leak with subsequent dissection into other anatomical spaces is called the Macklin effect. It is essential to have this mechanism in mind because most of these patients respond well to conservative treatment. When studying primary pneumoperitoneum, the cause should be studied carefully to discard visceral perforation, tracheal or esophageal rupture. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource covid-19, Pneumoperitoneum, barotrauma, macklin effect Identifier An unambiguous reference to the resource within a given context 10.7759/cureus.13200 Source A related resource from which the described resource is derived Cureus