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Functional studies of the coronavirus nonstructural proteins
Coronaviruses, including SARS-CoV, SARS-CoV-2, and MERS-CoV, have caused contagious and fatal respiratory diseases in humans worldwide. Notably, the coronavirus disease 19 (COVID-19) caused by SARS-CoV-2 spread rapidly in early 2020 and became a…
Position: 19767 (14 views)
Functional Role of Dietary Intervention to Improve the Outcome of COVID-19: A Hypothesis of Work
Background: On the 31 December 2019, the World Health Organization (WHO) was informed of a cluster of cases of pneumonia of unknown origin detected in Wuhan City, Hubei Province, China. The infection spread first in China and then in the rest of the…
Position: 16101 (19 views)
Functional genomics highlights differential induction of antiviral pathways in the lungs of SARS-CoV-infected macaques.
The pathogenesis of severe acute respiratory syndrome coronavirus (SARS-CoV) is likely mediated by disproportional immune responses and the ability of the virus to circumvent innate immunity. Using functional genomics, we analyzed early host…
Position: 1414 (56 views)
Functional Diversity in Ferns Is Driven by Species Richness Rather Than by Environmental Constraints
Functional traits determine how species interact with their abiotic and biotic environment. In turn, functional diversity describes how assemblages of species as a whole are adapted to their environment, which also determines how they might react to…
Position: 14099 (21 views)
Functional characterization of endogenous siRNA target genes in <it>Caenorhabditis elegans</it>
Abstract Background Small interfering RNA (siRNA) molecules mediate sequence specific silencing in RNA interference (RNAi), a gene regulatory phenomenon observed in almost all organisms. Large scale sequencing of small RNA libraries obtained from C.…
Position: 8735 (27 views)
Functional and Genetic Analysis of Coronavirus Replicase-Transcriptase Proteins.
The coronavirus replicase-transcriptase complex is an assembly of viral and cellular proteins that mediate the synthesis of genome and subgenome-sized mRNAs in the virus-infected cell. Here, we report a genetic and functional analysis of 19…
Position: 864 (64 views)
Functional and Genetic Analysis of Coronavirus Replicase-Transcriptase Proteins.
The coronavirus replicase-transcriptase complex is an assembly of viral and cellular proteins that mediate the synthesis of genome and subgenome-sized mRNAs in the virus-infected cell. Here, we report a genetic and functional analysis of 19…
Position: 781 (66 views)
Funciones de los servicios ecosistémicos en los sistemas ganaderos en Cuba
Objetivo: Analizar las funciones de los servicios ecosistémicos en los sistemas ganaderos para la producción de alimentos de forma sostenible en Cuba.Materiales y Métodos: Se analizó la situación actual de los servicios ecosistémicos como componentes…
Position: 8735 (27 views)
Funciones de costos internos y externos en un modelo estratégico de transporte de carga
Se revisan las funciones de costos internos y externos,con fines de modelación estratégica del transportede carga. Se estudian el costo interno del tiempo, elcosto interno de operación y cinco componentes delcosto externo: costo externo de la…
Position: 5213 (34 views)
Fulminant micro and macroangiopathic sequalae in a patient with COVID-19.
Position: 11177 (24 views)