126 10 20655 https://www.socictopen.socict.org/files/original/86574e8a9c5e8cb956f1967d08d0148c.pdf f4e2f1ee4dbd817ac5ada880572bf826 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource 2019-nCoV: Polite with children! Creator An entity primarily responsible for making the resource Désirée Caselli, Maurizio Aricò Description An account of the resource A novel epidemic is challenging the global health care system. Starting from probably November to December 2019, another Coronavirus entered the arena of human pathogens, to be then defined 2019- nCoV [...]. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context DOI: 10.4081/pr.2020.8495 Source A related resource from which the described resource is derived Pediatric Reports Publisher An entity responsible for making the resource available PAGEPress Publications Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Pediatrics, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/f60bcdc1ecb6419815c1c380a16871a4.pdf e31e66f6711086f46620871fbbe6bdc0 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Estimation Of Direct Medical Costs Of Middle East Respiratory Syndrome Coronavirus Infection: A Single-Center Retrospective Chart Review Study Creator An entity primarily responsible for making the resource AlRuthia Y, Somily AM, Alkhamali AS, Bahari OH, AlJuhani RJ, Alsenaidy M, Balkhi B Description An account of the resource Yazed AlRuthia,1,2 Ali M Somily,3 Amal S Alkhamali,1 Ohud H Bahari,1 Raneem J AlJuhani,1 Mohammad Alsenaidy,4 Bander Balkhi1,2 1Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia; 2Pharmacoeconomics Research Unit, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia; 3Microbiology Department, College of Medicine, King Saud University, Riyadh, Saudi Arabia; 4Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi ArabiaCorrespondence: Yazed AlRuthiaDepartment of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi ArabiaTel +996 114677483Fax +966 114677480Email yazeed@ksu.edu.saBackground: Among the countries affected by Middle East respiratory syndrome (MERS), Saudi Arabia was impacted the most, with 2,058 cases reported as of June 2019. However, the impact of the MERS epidemic on the Saudi economy is unknown.Purpose: The present study aimed to evaluate the direct medical costs associated with the management of MERS cases at a tertiary referral hospital in Riyadh, Saudi Arabia.Methods: The study involved a retrospective chart review of confirmed cases of MERS coronavirus (MERS-CoV) infections in a tertiary care referral center in Riyadh, Saudi Arabia, from January 2015 to October 2018. The collected data included sociodemographic characteristics, medical information, and the cost of hospitalization of each patient as estimated by micro-costing.Results: A complete set of relevant information was available only for 24 of 44 identified MERS-CoV cases. Patients were mostly females, and the mean age was 52 years. Diabetes, hypertension, and chronic kidney disease were the most frequent comorbidities. The length of hospital stay varied from 1 to 31 days, averaging 4.96 ± 7.29 days. Two of the 24 patients died. The total cost of managing a MERS case at the hospital ranged from $1278.41 to $75,987.95 with a mean cost of $12,947.03 ± $19,923.14.Conclusion: The findings of this study highlight the enormous expenses incurred by the Saudi health care system due to the MERS-CoV outbreak and the importance of developing an enforceable nationwide policy to control MERS-CoV transmission and infection.Keywords: Middle East respiratory syndrome coronavirus, costs and cost analysis, Saudi Arabia Date A point or period of time associated with an event in the lifecycle of the resource 2019 Subject The topic of the resource Middle East respiratory syndrome coronavirus, costs and cost analysis, Saudi Arabia Identifier An unambiguous reference to the resource within a given context DOI: Source A related resource from which the described resource is derived Infection and Drug Resistance Publisher An entity responsible for making the resource available Dove Medical Press Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases Language A language of the resource EN https://www.socictopen.socict.org/files/original/de735ecee5357eadcd1d6755d8d8bda6.pdf 1cb5c73952db52c92c10a0eefe48dc8c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus. Creator An entity primarily responsible for making the resource Ben Hu, Lei-Ping Zeng, Xing-Lou Yang, Xingyi Ge, Wei Zhang, Bei Li, Jiazheng Xie, Xurui Shen, Yunzhi Zhang, Ning Wang, Dongsheng Luo, Xiao-Shuang Zheng, Mei-Niang Wang, Peter Daszak, Lin-Fa Wang, Jie Cui, Zhengli Shi Description An account of the resource A large number of SARS-related coronaviruses (SARSr-CoV) have been detected in horseshoe bats since 2005 in different areas of China. However, these bat SARSr-CoVs show sequence differences from SARS coronavirus (SARS-CoV) in different genes (S, ORF8, ORF3, etc) and are considered unlikely to represent the direct progenitor of SARS-CoV. Herein, we report the findings of our 5-year surveillance of SARSr-CoVs in a cave inhabited by multiple species of horseshoe bats in Yunnan Province, China. The full-length genomes of 11 newly discovered SARSr-CoV strains, together with our previous findings, reveals that the SARSr-CoVs circulating in this single location are highly diverse in the S gene, ORF3 and ORF8. Importantly, strains with high genetic similarity to SARS-CoV in the hypervariable N-terminal domain (NTD) and receptor-binding domain (RBD) of the S1 gene, the ORF3 and ORF8 region, respectively, were all discovered in this cave. In addition, we report the first discovery of bat SARSr-CoVs highly similar to human SARS-CoV in ORF3b and in the split ORF8a and 8b. Moreover, SARSr-CoV strains from this cave were more closely related to SARS-CoV in the non-structural protein genes ORF1a and 1b compared with those detected elsewhere. Recombination analysis shows evidence of frequent recombination events within the S gene and around the ORF8 between these SARSr-CoVs. We hypothesize that the direct progenitor of SARS-CoV may have originated after sequential recombination events between the precursors of these SARSr-CoVs. Cell entry studies demonstrated that three newly identified SARSr-CoVs with different S protein sequences are all able to use human ACE2 as the receptor, further exhibiting the close relationship between strains in this cave and SARS-CoV. This work provides new insights into the origin and evolution of SARS-CoV and highlights the necessity of preparedness for future emergence of SARS-like diseases. Date A point or period of time associated with an event in the lifecycle of the resource 2017 Identifier An unambiguous reference to the resource within a given context DOI: 10.1371/journal.ppat.1006698 Source A related resource from which the described resource is derived PLoS Pathogens Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General), Immunologic diseases. Allergy Language A language of the resource EN https://www.socictopen.socict.org/files/original/2b4b1b9a02bad9d2a139e8fe0504d232.pdf e9914cbb70efad5a4368864796cda9ae Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Mapping the Global Network of Extracellular Protease Regulation in Staphylococcus aureus Creator An entity primarily responsible for making the resource Brittney D. Gimza, Maria I. Larias, Bridget G. Budny, Lindsey N. Shaw Description An account of the resource The complex regulatory role of the proteases necessitates very tight coordination and control of their expression. While this process has been well studied, a major oversight has been the consideration of proteases as a single entity rather than as 10 enzymes produced from four different promoters. As such, in this study, we comprehensively characterized the regulation of each protease promoter, discovering vast differences in the way each protease operon is controlled. Additionally, we broaden the picture of protease regulation using a global screen to identify novel loci controlling protease activity, uncovering a cadre of new effectors of protease expression. The impact of these elements on the activity of proteases and known regulators was characterized by producing a comprehensive regulatory circuit that emphasizes the complexity of protease regulation in Staphylococcus aureus.A primary function of the extracellular proteases of Staphylococcus aureus is to control the progression of infection by selectively modulating the stability of virulence factors. Consequently, a regulatory network exists to titrate protease abundance/activity to influence the accumulation, or lack thereof, of individual virulence factors. Herein, we comprehensively map this system, exploring the regulation of the four protease loci by known and novel factors. In so doing, we determined that seven major elements (SarS, SarR, Rot, MgrA, CodY, SaeR, and SarA) form the primary network of control, with the latter three being the most powerful. We note that expression of aureolysin is largely repressed by these factors, while the spl operon is subject to the strongest upregulation of any protease loci, particularly by SarR and SaeR. Furthermore, when exploring scpA expression, we find it to be profoundly influenced in opposing fashions by SarA (repressor) and SarR (activator). We also present the screening of >100 regulator mutants of S. aureus, identifying 7 additional factors (ArgR2, AtlR, MntR, Rex, XdrA, Rbf, and SarU) that form a secondary circuit of protease control. Primarily, these elements serve as activators, although we reveal XdrA as a new repressor of protease expression. With the exception or ArgR2, each of the new effectors appears to work through the primary network of regulation to influence protease production. Collectively, we present a comprehensive regulatory circuit that emphasizes the complexity of protease regulation and suggest that its existence speaks to the importance of these enzymes to S. aureus physiology and pathogenic potential. Date A point or period of time associated with an event in the lifecycle of the resource 2019 Subject The topic of the resource Staphylococcus aureus, gene regulation, proteases, transcriptional regulation, Virulence factors Identifier An unambiguous reference to the resource within a given context DOI: 10.1128/mSphere.00676-19 Source A related resource from which the described resource is derived mSphere Publisher An entity responsible for making the resource available American Society for Microbiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology Language A language of the resource EN https://www.socictopen.socict.org/files/original/42ab98a820134d170bf59a3582f2173f.pdf aac8986ae64ce109827b6758954f9292 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The Experience of a Comparative Analysis of the Incidence of Pneumonia and Acute Respiratory Infections of the Upper Respiratory Tract after the Introduction of a System of Epidemiological Monitoring of Pneumonia Creator An entity primarily responsible for making the resource N.A. Kravchenko, T.A. Gavrilova, M. I. Khakimova, V. B. Kazanova, E. I. Vasilyeva, A. D. Botvinkin Description An account of the resource The system of epidemiological surveillance of community-acquired pneumonia (VP) in the Russian Federation (RF) has changed since 2011. As a result, additional opportunities have emerged for a comparative analysis of the incidence of EP and ARVI. The goal is to give a comparative description of the incidence of CAP and ARVI by age groups, territories and seasonality, taking into account the results of a selective laboratory examination of patients.Materials and methods. A retrospective descriptive epidemiological study on the results of epidemiological surveillance at the regional level (Irkutsk Region, 2012–2016) was conducted. For 2016, the dynamics of the patient’s number with influenza and acute respiratory viral infections (n = 706460) and VP (n = 15279) reported by weeks, as well as the results of selective PCR examination of 1788 patients for 13 viral and bacterial pathogens were analyzed.Results. Over 5 years, the incidence of the VP increased from 377.6 (370.0–385.2) per 100 thousand to 588.3 (578.7–597.9), the average annual growth rate was + 35.8%. At the same time, the incidence of ARVI decreased at an average annual rate of –2.9%. When comparing the incidence of CAP and ARVI in municipalities, it was found weakly correlation only (ρ = 0.172, p> 0.05). In contrast, in the analysis of seasonality, a direct strong correlation was found between SARS and EP by weeks of the year (ρ = 0.887, p <0.05). For an average of 5 years, there were 52 cases of ARVI per 1 case of EP. For children, there were no significant differences in this indicator by the seasons of the year, whereas in adults, EP were recorded relatively more often in summer and spring than in winter and autumn (p <0.05). Significant differences in the frequency of positive findings for the seasons of the year were found for pneumococcus, rhinoviruses, influenza A and RS viruses. The recorded incidence of CAP and ARVI was characterized by a weak correlation link by territory and a strong link by weeks.Conclusion. The introduction of the epidemiological monitoring system for pneumonia allowed to identify differences in the intra-annual dynamics of EF and ARVI among adults and children. This is the basis for correcting the tactics laboratory monitoring and prophylaxis of acute respiratory infections. Date A point or period of time associated with an event in the lifecycle of the resource 2019 Subject The topic of the resource Community-acquired pneumonia, acute respiratory infections, incidence, seasonality, pcr monitoring Identifier An unambiguous reference to the resource within a given context DOI: 10.31631/2073-3046-2019-18-1-96-104 Source A related resource from which the described resource is derived Эпидемиология и вакцинопрофилактика Publisher An entity responsible for making the resource available Numikom LLC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Epistemology. Theory of knowledge Language A language of the resource RU https://www.socictopen.socict.org/files/original/7cc6b895efeb9f50dea76ee22c6611b5.pdf 2872bf07434a5c55d21a0c4a47a0bcdf Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Occurrence of Influenza A (H1N1) in Alagoas (2016-2019)/ Ocorrência de Influenza A (H1N1) em Alagoas (2016-2019) Creator An entity primarily responsible for making the resource Ellen Karollyne Santos Lopes, Allana Caroline Bonfim Costa, Karoline Barbosa Gomes, Samara dos Santos Oliveira, Tariqat Sofia Machado Montiel, Claudimary Bispo dos Santos Description An account of the resource : Influenza A is a viral respiratory tract disease, which is transmitted on a large scale by theMyxovirus influenzae virus, through person-to-person contact by dissemination of droplets containing viralparticles. Among influenza A subtypes, the H1N1 and H3N2 subtypes are those that are in activecirculation among humans. The main symptoms arising from the infection are high fever, muscle pain,headache, cough and tiredness. In this context, the present study aimed to quantify the cases of InfluenzaA of the subtype H1N1, in the State of Alagoas, during the period from 2016 to the first half of 2019. Datawere collected through a search on the Ministry of Health website of SARS cases for influenza A of theH1N1 subtype registered in epidemiological reports. In Alagoas, 2016 presented the highest number ofcases of H1N1, 52 cases and 12 deaths, while in 2017 there was the lowest expressiveness, with 06positive cases and 03 deaths. In 2018, 32 cases of H1N1 and 03 deaths were reported. In the first half of2019, 21 cases and 3 deaths were confirmed, but 37 cases and 05 deaths are still being investigated.According to the data obtained, it was concluded that, in 2016, the H1N1 viral disease in Alagoas wasmore expressive, whereas in 2017, there were few cases, as was also observed in the country in general. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource viral disease; epidemiological reports; respiratory tract Identifier An unambiguous reference to the resource within a given context DOI: 10.17648/diversitas-journal-v5i1-925 Source A related resource from which the described resource is derived Diversitas Journal Publisher An entity responsible for making the resource available Universidade Estadual de Alagoas Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Education, Science, Social Sciences Language A language of the resource EN, PT https://www.socictopen.socict.org/files/original/dfa64c080c6f6d703063ab6cb941e13a.pdf af8588027a29485bd5630a80ec6509cc Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource EVALUATION OF FORMAL RISK ASSESSMENT IMPLEMENTATION OF MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS IN 2018 Creator An entity primarily responsible for making the resource Della Safera Pradanti Description An account of the resource Background: Confirmed cases of Middle East respiratory syndrome caused by coronavirus (MERS-CoV) were not found until the end of February 2019 in Indonesia. The spreading threat of MERS-CoV disease in Indonesia is still quite vast, mainly because of the amount of international travel from Indonesia to Saudi Arabia for the purpose of Hajj and Umrah, vacationing, working, or settling in the Arabian Peninsula. Purpose: The aim of this study is to evaluate the implementation of formal risk assessment (FRA) and MERS-CoV risk in Indonesia in 2018, having regard to threat, vulnerability, and capacity. Method: This study is a non-reactive observation study presented descriptively using the literature method and in-depth interviews with staff of the subdirectorat of Penyakit Infeksi Emerging Kementerian Kesehatan Republik. Decision-making for the threat category and vulnerability category is based on the highest threat index and vulnerability values, while the capacity category is based on the lowest capacity index value. Results: This study shows that there are three threat subcategories and two vulnerability subcategories that have high index scores and eight capacity subcategories that have low scores. Conclusion: The implementation of risk assessment for MERS-CoV with the FRA method as a whole has been maximally pursued. However, there are still shortcomings in the results of the research that need to be improved through further interventions to reduce the subcategory values that are high in the threat and vulnerability index and to increase the value of the low capacity index. Date A point or period of time associated with an event in the lifecycle of the resource 2019 Subject The topic of the resource Evaluation, Middle East respiratory syndrome coronavirus, formal risk assessment, emerging infectious disease Identifier An unambiguous reference to the resource within a given context DOI: 10.20473/jbe.V7I32019.197-206 Source A related resource from which the described resource is derived Jurnal Berkala Epidemiologi Publisher An entity responsible for making the resource available Universitas Airlangga Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Public aspects of medicine Language A language of the resource ID https://www.socictopen.socict.org/files/original/02a6a52198e6f2682662b092f29df9a8.pdf cfb9c514d79a0d7419d95bdba765d667 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource COMPOUNDS OF BISMUTH AND ITS PORPHYRINE COMPLEXES: APPLICATION, STRUCTURE AND PROPERTIES Creator An entity primarily responsible for making the resource A. S. Gorshkova, V. D. Rumyantseva, A. F. Mironov Description An account of the resource Bismuth and its compounds have been known since ancient times and now are widely used in practice in various fields. Bismuth use in medicine can be traced back to the Middle Ages, and its wide application is due to its very low toxicity - for most bismuth compounds it is less than for sodium chloride. Bismuth and its compounds, in particular salts, are used in medical practice in the treatment of diseases such as spirochetosis, gastric and duodenal ulcer, leishmaniasis and coronaviral infection, as well as in cancer therapy. In addition to solid preparations liquid peroral pharmaceutical forms have been developed for the treatment of diarrhea, colitis, ulcers etc. Bismuth preparations are used in stomatology for the treatment of inflammatory diseases of paradontium. The review considers the syntheses and properties of bismuth complexes with natural and synthetic porphyrins, which are used in medicine and other fields of science and technology. Considerable attention is paid to the structure features of bismuth porphyrins complexes, their dimeric structures, and the influence of various extra ligands. The counterion nature and structure make a substantial contribution in solving the problem of complexes stability. The central bismuth atom in these complexes extends far above the plane of the macrocycle due to the large ionic radius. Thus, the counterions action on the conformation, physicochemical properties and stability of metal porphyrins complexes is shown. A separate section is devoted to unique and interesting properties of bismuth porphyrins complexes, such as fluorescence and color variation of crystals. Date A point or period of time associated with an event in the lifecycle of the resource 2018 Subject The topic of the resource bismuth, porphyrins, bismuth complexes, dimer structures, Leishmaniasis, SARS, coronaviral infection Identifier An unambiguous reference to the resource within a given context DOI: 10.32362/2410-6593-2018-13-2-5-20 Source A related resource from which the described resource is derived Тонкие химические технологии Publisher An entity responsible for making the resource available MIREA - Russian Technological University Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Chemistry Language A language of the resource RU https://www.socictopen.socict.org/files/original/99c63075f8319f9821ae555dd2ef8cfd.pdf aca7970082baf19a9794f0f4387d6341 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource La comunicación científica y el acceso abierto en la contención de enfermedades: El caso del Coronavirus novel 2019 (2019-nCoV) Creator An entity primarily responsible for making the resource Franz K. Arteaga-Livias, Alfonso J. Rodriguez-Morales Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context DOI: 10.35839/repis.4.1.613 Source A related resource from which the described resource is derived Revista Peruana de Investigación en Salud Publisher An entity responsible for making the resource available Universidad Nacional Hermilio Valdizán Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Public aspects of medicine, Medicine (General) Language A language of the resource ES https://www.socictopen.socict.org/files/original/c966db586949712bd0320bbf40c0e46e.pdf 75ddca6b898ec42bb63e6d6039c767eb Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Respiratory viruses in mechanically ventilated patients: a pilot study Creator An entity primarily responsible for making the resource Raquel Nazareth, Maria-Jesus Chasqueira, Maria-Lúcia Rodrigues, Carolina Paulino, Catarina Conceição, Lia Lêdo, Úrsula Segura, Madalena Santos, António Messias, Pedro Póvoa, Paulo Paixão Description An account of the resource Abstract Background Respiratory virome is an integral part of the human microbiome and its characterization may contribute to a better understanding of the changes that arise in the disease and, consequently, influence the approach and treatment of patients with acute lower respiratory infections. The aim of this study was to evaluate the presence of respiratory viruses in the lower airways of individuals undergoing invasive mechanical ventilation, with and without acute lower respiratory infection (respectively WRI and WORI groups). Methods We studied 44 mini-bronchoalveolar lavage samples (collected with a double catheter, Combicath® kit) from patients with mean age in the seventh decade, 20 from WORI group and 24 from WRI group, who were hospitalized for acute respiratory failure in Intensive Care Units of two hospitals in the Lisbon area. Real-time PCR was applied to verify analyse the presence of 15 common respiratory viruses (adenovirus, human bocavirus, influenza virus A and B, repiratory syncytial virus, human parainfluenza virus types 1, 2, 3 and 4, human enterovirus, human rhinovirus, human metapneumovirus, human coronavirus group 1 (229E, NL63) and 2 (OC43, HKU1). Results Respiratory viruses were detected in six of the 20 patients in the WORI group: influenza AH3 (n = 2), parainfluenza virus 1/3 (n = 2), human rhinovirus (n = 2), respiratory syncytial virus (n = 1) and human metapneumovirus (n = 1). In the WRI group, respiratory viruses were detected in 12 of the 24 patients: influenza AH3 (n = 3), human rhinovirus (n = 3), respiratory syncytial virus (n = 3), human metapneumovirus (n = 3), human bocavirus (n = 2) and human enterovirus (n = 1). Simultaneous detection of two viruses was recorded in two samples in both groups. Conclusions The results of this study suggest the presence of common respiratory viruses in the lower respiratory tract without causing symptomatic infection, even in carefully collected lower samples. This may have important implications on the interpretation of the results on the diagnostic setting. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Human microbiome, respiratory virome, Respiratory viruses, real-time PCR Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s12890-020-1082-5 Source A related resource from which the described resource is derived BMC Pulmonary Medicine Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Diseases of the respiratory system Language A language of the resource EN