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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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        <name>Dublin Core</name>
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            <name>Title</name>
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                <text>Quantifying the impact of physical distance measures on the transmission of COVID-19 in the UK</text>
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            <name>Creator</name>
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                <text>G James Rubin, Petra Klepac, W. John Edmunds, Kiesha Prem, Kevin van Zandvoort, Christopher I. Jarvis, Amy Gimma, CMMID COVID-19 working group</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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                <text>Abstract Background To mitigate and slow the spread of COVID-19, many countries have adopted unprecedented physical distancing policies, including the UK. We evaluate whether these measures might be sufficient to control the epidemic by estimating their impact on the reproduction number (R 0, the average number of secondary cases generated per case). Methods We asked a representative sample of UK adults about their contact patterns on the previous day. The questionnaire was conducted online via email recruitment and documents the age and location of contacts and a measure of their intimacy (whether physical contact was made or not). In addition, we asked about adherence to different physical distancing measures. The first surveys were sent on Tuesday, 24 March, 1 day after a “lockdown” was implemented across the UK. We compared measured contact patterns during the “lockdown” to patterns of social contact made during a non-epidemic period. By comparing these, we estimated the change in reproduction number as a consequence of the physical distancing measures imposed. We used a meta-analysis of published estimates to inform our estimates of the reproduction number before interventions were put in place. Results We found a 74% reduction in the average daily number of contacts observed per participant (from 10.8 to 2.8). This would be sufficient to reduce R 0 from 2.6 prior to lockdown to 0.62 (95% confidence interval [CI] 0.37–0.89) after the lockdown, based on all types of contact and 0.37 (95% CI = 0.22–0.53) for physical (skin to skin) contacts only. Conclusions The physical distancing measures adopted by the UK public have substantially reduced contact levels and will likely lead to a substantial impact and a decline in cases in the coming weeks. However, this projected decline in incidence will not occur immediately as there are significant delays between infection, the onset of symptomatic disease, and hospitalisation, as well as further delays to these events being reported. Tracking behavioural change can give a more rapid assessment of the impact of physical distancing measures than routine epidemiological surveillance.</text>
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                <text>2020</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>Disease outbreak, Reproduction number, Pandemic, nCoV, COVID-19, Contact survey</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>DOI: 10.1186/s12916-020-01597-8</text>
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                <text>BMC Medicine</text>
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                <text>BMC</text>
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                <text>Medicine</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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            <description>A name given to the resource</description>
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                <text>Quantifying the role of social distancing, personal protection and case detection in mitigating COVID-19 outbreak in Ontario, Canada</text>
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            <description>An entity primarily responsible for making the resource</description>
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                <text>Kyeongah Nah, Jianhong Wu, Nicola Luigi Bragazzi, Biao Tang, Zachary McCarthy</text>
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                <text>Abstract Public health interventions have been implemented to mitigate the spread of coronavirus disease 2019 (COVID-19) in Ontario, Canada; however, the quantification of their effectiveness remains to be done and is important to determine if some of the social distancing measures can be relaxed without resulting in a second wave. We aim to equip local public health decision- and policy-makers with mathematical model-based quantification of implemented public health measures and estimation of the trend of COVID-19 in Ontario to inform future actions in terms of outbreak control and de-escalation of social distancing. Our estimates confirm that (1) social distancing measures have helped mitigate transmission by reducing daily infection contact rate, but the disease transmission probability per contact remains as high as 0.145 and case detection rate was so low that the effective reproduction number remained higher than the threshold for disease control until the closure of non-essential business in the Province; (2) improvement in case detection rate and closure of non-essential business had resulted in further reduction of the effective control number to under the threshold. We predict the number of confirmed cases according to different control efficacies including a combination of reducing further contact rates and transmission probability per contact. We show that improved case detection rate plays a decisive role to reduce the effective reproduction number, and there is still much room in terms of improving personal protection measures to compensate for the strict social distancing measures.</text>
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              <elementText elementTextId="32348">
                <text>2020</text>
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                <text>mathematical model, parameter estimation, personal protection, COVID-19, Control reproduction number, Effective reproduction number</text>
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            <name>Identifier</name>
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              <elementText elementTextId="32350">
                <text>DOI: 10.1186/s13362-020-00083-3</text>
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              <elementText elementTextId="32351">
                <text>Journal of Mathematics in Industry</text>
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                <text>SpringerOpen</text>
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                <text>Mathematics, Industry</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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              </elementTextContainer>
            </element>
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    <itemType itemTypeId="1">
      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="37099">
                <text>Quantifying the roles of vomiting, diarrhea, and residents vs. staff in norovirus transmission in U.S. nursing home outbreaks.</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="37100">
                <text>David Young, Benjamin A. Lopman, Aron J. Hall, Paul A. Gastañaduy, Prabasaj Paul, Carly Adams, Zach Marsh</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="37101">
                <text>The role of individual case characteristics, such as symptoms or demographics, in norovirus transmissibility is poorly understood. Six nursing home norovirus outbreaks occurring in South Carolina, U.S. from 2014 to 2016 were examined. We aimed to quantify the contribution of symptoms and other case characteristics in norovirus transmission using the reproduction number (REi) as an estimate of individual case infectivity and to examine how transmission changes over the course of an outbreak. Individual estimates of REi were calculated using a maximum likelihood procedure to infer the average number of secondary cases generated by each case. The associations between case characteristics and REi were estimated using a weighted multivariate mixed linear model. Outbreaks began with one to three index case(s) with large estimated REi's (range: 1.48 to 8.70) relative to subsequent cases. Of the 209 cases, 155 (75%) vomited, 164 (79%) had diarrhea, and 158 (76%) were nursing home residents (vs. staff). Cases who vomited infected 2.12 (95% CI: 1.68, 2.68) times the number of individuals as non-vomiters, cases with diarrhea infected 1.39 (95% CI: 1.03, 1.87) times the number of individuals as cases without diarrhea, and resident-cases infected 1.53 (95% CI: 1.15, 2.02) times the number of individuals as staff-cases. Index cases tended to be residents (vs. staff) who vomited and infected considerably more secondary cases compared to non-index cases. Results suggest that individuals, particularly residents, who vomit are more infectious and tend to drive norovirus transmission in U.S. nursing home norovirus outbreaks. While diarrhea also plays a role in norovirus transmission, it is to a lesser degree than vomiting in these settings. Results lend support for prevention and control measures that focus on cases who vomit, particularly if those cases are residents.</text>
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            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2020</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="37103">
                <text>DOI: 10.1371/journal.pcbi.1007271</text>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="37104">
                <text>PLoS Computational Biology</text>
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          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="37105">
                <text>Public Library of Science (PLoS)</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Biology (General)</text>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
              <elementTextContainer>
                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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              </elementTextContainer>
            </element>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="17201">
                <text>Quantitative detection of human Malawi polyomavirus in nasopharyngeal aspirates, sera, and feces in Beijing, China, using real-time TaqMan-based PCR</text>
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          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="17202">
                <text>Fen-lian Ma, Dan-di Li, Tianli Wei, Jin-song LI, Li-Shu Zheng</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>Abstract Background Human Malawi polyomavirus (MWPyV) was discovered in 2012, but its prevalence and clinical characteristics are largely unknown. Methods We used real-time TaqMan-based PCR to detect MWPyV in the feces (n = 174) of children with diarrhea, nasopharyngeal aspirates (n = 887) from children with respiratory infections, and sera (n = 200) from healthy adults, and analyzed its clinical characteristics statistically. All the MWPyV-positive specimens were also screened for other common respiratory viruses. Results Sixteen specimens were positive for MWPyV, including 13 (1.47%) respiratory samples and three (1.7%) fecal samples. The samples were all co-infected with other respiratory viruses, most commonly with influenza viruses (69.2%) and human coronaviruses (30.7%). The MWPyV-positive children were diagnosed with bronchopneumonia or viral diarrhea. They ranged in age from 12 days to 9 years, and the most frequent symptoms were cough and fever. Conclusions Real-time PCR is an effective tool for the detection of MWPyV in different types of samples. MWPyV infection mainly occurs in young children, and fecal–oral transmission is a possible route of its transmission.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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              <elementText elementTextId="17204">
                <text>2017</text>
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            <name>Subject</name>
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                <text>Human Malawi polyomavirus (MWPyV), Taqman real-time PCR, nasopharyngeal aspirate, feces, respiratory virus</text>
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            <name>Identifier</name>
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                <text>DOI: 10.1186/s12985-017-0817-2</text>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="17207">
                <text>Virology Journal</text>
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                <text>BMC</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Infectious and parasitic diseases</text>
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                <text>EN</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Quantitative Evaluation of Aerosol Generation from Non-contact Tonometry and its Correlation with Tear Film Characteristics.</text>
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                <text>Weiting Hao, Jianhui Wu, Xinheng Zhao, Danni Liang, Xingchen Yu, Huazheng Cao, Yan Wang</text>
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                <text>Ophthalmologists are inevitably exposed to tears and ocular discharge during ophthalmologic examinations and are at high risk for SARS-CoV-2 infection. To understand the role of aerosols in disease transmission, we adopted a prospective cross-sectional study design and investigated the count and size distribution of aerosols generated by a non-contact tonometer and its correlation with individual tear film characteristics. This study constituted two parts. The study population included outpatients who underwent an intraocular pressure examination in an intraocular pressure examination room (Part I) and 20 participants who underwent an intraocular pressure examination in a laboratory (Part II). The following main outcomes were measured: aerosol counts at 0, 50, 100, 150, and 200 cm from the non-contact tonometer (Part I); aerosol counts after each participant underwent non-contact tonometry, and lipid layer thickness score and tear film break-up time (Part II). The aerosol count decreased with increasing distance from the tonometer. The aerosol count at 0 cm had the highest value compared to that at other distances. For aerosols of diameters 0.25-0.5 μm and 0.5-1.0 μm, the count decreased at 50 cm and remained stable at further distances. For aerosols of diameters 1.0-2.5 μm and ≥ 2.5 μm, the count dropped progressively at all five distances. The aerosol count from each tonometer correlated positively with the lipid layer thickness score (r = 0.490, P = 0.028), whereas the aerosol count correlated negatively with the tear film break-up time (r =  - 0.675, P = 0.001). Aerosols tended to coagulate during diffusion. A 50-cm distance from the tonometer could confer safety from aerosols with &lt; 1.0-μm diameter. Aerosols generated during non-contact tonometry could contain a lipid layer component. Moreover, tear film stability could affect aerosol generation. Protective eyewear is recommended for reducing infection risk from aerosols. Individual tear film characteristics should be considered during non-contact tonometry.</text>
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                <text>2021</text>
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                <text>covid-19, ophthalmology, aerosols, SARS-CoV-2, tear film, Non-contact tonometry</text>
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                <text>10.1007/s12325-021-01740-8</text>
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                <text>Advances in therapy</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Quantitative lung lesion features and temporal changes on chest CT in patients with common and severe SARS-CoV-2 pneumonia.</text>
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              <elementText elementTextId="60992">
                <text>Yue Zhang, Ying Liu, Honghan Gong, Lin Wu</text>
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            <description>An account of the resource</description>
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                <text>The purpose of this study was to describe the temporal evolution of quantitative lung lesion features on chest computed tomography (CT) in patients with common and severe types of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia. Records of patients diagnosed with SARS-CoV-2 pneumonia were reviewed retrospectively from 24 January 2020 to 15 March 2020. Patients were classified into common and severe groups according to the diagnostic criteria of severe pneumonia. The quantitative CT features of lung lesions were automatically calculated using artificial intelligence algorithms, and the percentages of ground-glass opacity volume (PGV), consolidation volume (PCV) and total lesion volume (PTV) were determined in both lungs. PGV, PCV and PTV were analyzed based on the time from the onset of initial symptoms in the common and severe groups. In the common group, PTV increased slowly and peaked at approximately 12 days from the onset of the initial symptoms. In the severe group, PTV peaked at approximately 17 days. The severe pneumonia group exhibited increased PGV, PCV and PTV compared with the common group. These features started to appear in Stage 2 (4-7 days from onset of initial symptoms) and were observed in all subsequent stages (p</text>
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                <text>10.1371/journal.pone.0236858</text>
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                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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              <description>A name given to the resource</description>
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                  <text>Agricultura sostenible</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Agricultura sostenible</text>
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                <text>Quanto Mais, Melhor? O Desafio da Gestão de Projetos no Programa Semiárido da ONG Agricultura Sustentável</text>
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                <text>Milene Felix de Almeida, Diana Lúcia Teixeira de Carvalho</text>
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            <description>An account of the resource</description>
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                <text>O caso de ensino aborda os desafios relacionados ao gerenciamento de projetos vivenciados por uma Organização Não Governamental, a “Agricultura Sustentável”. O foco do caso é direcionado para um dos programas que a organização desenvolve, o Programa Semiárido, que tem como objetivo fortalecer a agricultura familiar e promover o desenvolvimento rural por meio de um modelo de agricultura que valoriza o respeito à natureza, aos recursos naturais e ao homem do campo. Ao longo dos anos, o programa cresceu devido à aprovação de novos projetos, captação de maior volume de recursos e contratação de pessoal, consequência das parcerias realizadas com cooperação internacional, agentes públicos federais e estaduais, que viabilizam ações em 14 municípios de atuação. Contudo, surgiram desafios e inconvenientes na gestão dos projetos, o que exigiu novas estratégias de atuação, bem como tomadas de decisão relativas à continuidade do desenvolvimento apenas dos projetos atuais, o que já tem sido difícil de gerenciar, ou da ampliação da quantidade de projetos, considerando o aumento da demanda dos beneficiários e a disponibilidade de recursos.</text>
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                <text>2019</text>
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            <name>Subject</name>
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                <text>Agricultura Familiar, Gestão de Projetos, ONGS</text>
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            <description>An unambiguous reference to the resource within a given context</description>
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                <text>10.21714/2019_v9i241973</text>
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            <description>A related resource from which the described resource is derived</description>
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                <text>Teoria e Prática em Administração</text>
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            <description>An entity responsible for making the resource available</description>
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                <text>Universidade Federal da Paraíba</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Social Sciences, Business, Commerce</text>
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            <description>A related resource</description>
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                <text>&lt;a href="http://periodicos.ufpb.br/index.php/tpa/article/view/41973" target="_blank" rel="noreferrer noopener"&gt;http://periodicos.ufpb.br/index.php/tpa/article/view/41973&lt;/a&gt;</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Quantum Leap from Gold and Silver to Aluminum Nanoplasmonics for Enhanced Biomedical Applications</text>
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                <text>Dang Nguyen, Sharad Ambardar, Grace Binder, Zachary  W. Withers, Dmitri  V. Voronine</text>
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            <description>An account of the resource</description>
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                <text>Nanotechnology has been used in many biosensing and medical applications, in the form of noble metal (gold and silver) nanoparticles and nanostructured substrates. However, the translational clinical and industrial applications still need improvements of the efficiency, selectivity, cost, toxicity, reproducibility, and morphological control at the nanoscale level. In this review, we highlight the recent progress that has been made in the replacement of expensive gold and silver metals with the less expensive aluminum. In addition to low cost, other advantages of the aluminum plasmonic nanostructures include a broad spectral range from deep UV to near IR, providing additional signal enhancement and treatment mechanisms. New synergistic treatments of bacterial infections, cancer, and coronaviruses are envisioned. Coupling with gain media and quantum optical effects improve the performance of the aluminum nanostructures beyond gold and silver.</text>
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                <text>cancer, Bacteria, UV, photothermal therapy, hot electron, aluminum plasmonics</text>
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                <text>DOI: 10.3390/app10124210</text>
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                <text>Applied Sciences</text>
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                <text>MDPI AG</text>
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                <text>Biology (General), Technology, Physics, Chemistry, Engineering (General). Civil engineering (General)</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Quarantine acceptance and adherence: qualitative evidence synthesis and conceptual framework.</text>
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                <text>Pradeep Sopory, Julie M Novak, Jane P Noyes</text>
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                <text>Emergent infectious diseases often lack medical treatment or preventive vaccines, thus requiring non-pharmaceutical interventions such as quarantine to reduce disease transmission. Quarantine, defined as the separation and restriction of movement of healthy people who have potentially been exposed to the disease, remains contentious especially when the risks and benefits are not fully discussed and not effectively communicated to the people by the organizations who impose this public health measure. A qualitative evidence synthesis was conducted to examine the phenomenon of adherence to quarantine focused on the following questions: What strategies affect adherence to quarantine? What are the barriers and facilitators to quarantine acceptance? What benefits and harms of quarantine have been described or measured? The evidence synthesis produced 18 findings assessed with high confidence. The findings were used to construct a conceptual framework for inter- and within-organization coordination and public communication that includes the following topics for consideration: desired orientation for implementation; population demographics; perceptions of messages; prior acceptance of quarantine; likelihood of impacts of quarantine; perceptions of health infrastructure; and perceptions of policy importance. The findings and conceptual framework can guide development of effective non-pharmaceutical interventions and as such have direct relevance to public health policy and decision-making for intervening in emergent infectious diseases outbreak such as the ongoing COVID-19 pandemic.</text>
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                <text>nonpharmaceutical interventions, Qualitative evidence synthesis, conceptual framework, infectious disease pandemic, Public health quarantine</text>
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                <text>10.1007/s10389-021-01544-8</text>
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                <text>Zeitschrift fur Gesundheitswissenschaften = Journal of public health</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Ying-Hen Hsieh, Chwan-Chuan King, Cathy W.S. Chen, Mei-Shang Ho, Jen-Yu Lee, Feng-Chi Liu, Yi-Chun Wu</text>
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                <text>During the 2003 outbreak of severe acute respiratory syndrome (SARS) in Taiwan, &gt;150,000 persons were quarantined, 24 of whom were later found to have laboratory-confirmed SARS-coronavirus (SARS-CoV) infection. Since no evidence exists that SARS-CoV is infective before the onset of symptoms and the quarantined persons were exposed but not symptomatic, we questioned the quarantine’s effectiveness. Using the SARS Taiwan quarantine data, we found that the onset-to-diagnosis time of previously quarantined confirmed case-patients was significantly shortened compared to that for those who had not been quarantined. Thus, quarantine for SARS in Taiwan screened potential infective persons for swift diagnosis and hospitalization after onset, thereby indirectly reducing infections. Full-scale quarantine measures implemented on April 28 led to a significant improvement in onset-to-diagnosis time of all SARS patients, regardless of previous quarantine status. We discuss the temporal effects of quarantine measures and other interventions on detection and isolation as well as the potential usefulness of quarantine in faster identification of persons with SARS and in improving isolation measures.</text>
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                <text>2005</text>
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                <text>SARS, emerging infectious disease, quarantine, intervention, Taiwan, research</text>
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                <text>DOI: 10.3201/eid1102.040190</text>
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                <text>Emerging Infectious Diseases</text>
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                <text>Centers for Disease Control and Prevention</text>
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            <name>Coverage</name>
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                <text>Infectious and parasitic diseases, Medicine</text>
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            <name>Language</name>
            <description>A language of the resource</description>
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                <text>EN</text>
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