1633 10 20655 https://www.socictopen.socict.org/files/original/0e3fdf1aeb356b6f3f1fdd1c72171ac7.pdf 7d8c2489cb2f5fac70344fe786684975 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Lineamientos del Colegio Colombiano de Terapia Ocupacional para la atención hospitalaria aguda y subaguda de pacientes con COVID-19 Creator An entity primarily responsible for making the resource Sylvia Cristina Duarte Torres, Pamela Talero Cabrejo, Viviana Marcela León Perilla, Francy Guacaneme García, Ruth Montufar Dulce, María Helena Rubio Grillo, Laine Yolanda Beltrán Description An account of the resource El amplio espectro clínico de la enfermedad COVID-19 tiene importantes implicaciones funcionales para el cuidado hospitalario agudo y subagudo en unidades de cuidado intensivo. Ante la emergencia sanitaria desencadenada por esta enfermedad, el Colegio Colombiano de Terapia Ocupacional convocó a un grupo de profesionales expertas en el área para proveer lineamientos para terapeutas ocupacionales que participan en la rehabilitación temprana de pacientes con COVID-19 en Colombia. Se realizó una revisión de literatura sobre la clasificación y las manifestaciones clínicas de la enfermedad, la efectividad de la rehabilitación temprana adulta, pediátrica y neonatal, y el rol y la experiencia de profesionales en Terapia Ocupacional en el uso de guías de salud existentes. Un consenso de expertas determinó la aplicabilidad de los lineamientos al contexto colombiano. Terapia Ocupacional, como parte del equipo de rehabilitación temprana, juega un papel fundamental en la restauración y el mantenimiento de la independencia funcional; la adaptación del ambiente y el acondicionamiento holístico gradual de las funciones respiratorias, cardiovasculares, sensoriomotoras y cognitivas durante las actividades básicas cotidianas, y la prevención del deterioro físico, mental, espiritual y social de la persona hospitalizada y su familia. Estos lineamientos constituyen un recurso técnico y educativo relevante para la Terapia Ocupacional hospitalaria. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource hospital, covid-19, Terapia Ocupacional, cuidado intensivo, servicios de rehabilitación Identifier An unambiguous reference to the resource within a given context 10.25214/25907816.951 Source A related resource from which the described resource is derived Ocupación Humana Publisher An entity responsible for making the resource available Colegio Colombiano de Terapia Ocupacional Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Public aspects of medicine, Industrial hygiene. Industrial welfare https://www.socictopen.socict.org/files/original/b9ecb2d6b779bebcb7888d9dd951c144.pdf d566ced22734f1a3a2044035f794c95d Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Doing Qualitative Research during the Covid-19 Pandemic of 2020 Creator An entity primarily responsible for making the resource Anna Sedysheva Description An account of the resource In this paper I examine how the pandemic and quarantine of 2020 affected qualitative research. Employing personal narrative as a method, I show what disadvantages researchers may have met with whilst conducting their studies. The unprecedented circumstances of the restrictions and uncertainty caused by the Covid-19 crisis have had a dramatic impact on the public mental health of individuals, including academic researchers. Many online tools are very useful for qualitative researchers, but are not a substitute for face-to-face research. In this article I explain these issues more thoroughly and discuss the challenges that researchers have faced during the period of the Covid-19 pandemic. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource mental health, Pandemic, feminist research Identifier An unambiguous reference to the resource within a given context 10.18061/ask.v29i1.0005 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Social sciences (General) https://www.socictopen.socict.org/files/original/d77a4732575da413da91c3c6d9536cfe.pdf 0599ed2977a23577ee320dbf9812a974 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Proposal for a Fuzzy Model to Assess Cost Overrun in Healthcare Due to Delays in Treatment Creator An entity primarily responsible for making the resource José M. Brotons-Martínez, Manuel E. Sansalvador-Sellés Description An account of the resource Apart from the effects of treating those infected with COVID-19, the pandemic has also affected treatment for other diseases, which has been either interrupted or canceled. The aim of this paper is to provide a financial model for obtaining the cost overrun resulting from the worsening of illnesses and deaths for each of the causes considered. To achieve this, first deaths have been classified into causes of death and for each of these causes, an estimation has been made of the worsening condition of patients due to delay in treatment. Through these data, a fuzzy relation between deaths and the worsening condition of patients can be obtained. Next, the expertise process has been used to estimate cost overrun in relation to patients’ pathologies. The experts’ opinions have been aggregated using ordered weighted average (OWA). Lastly, using fuzzy logic again, a correction coefficient has been determined, which optimizes the future implementation of the proposed model without the need for a new estimation of inputs. The paper concludes with a numerical example for a better comprehension of the proposed theoretical model. Ultimately, it provides the scientific community in general and in particular managers of public administration entities with a novel tool for improving the efficiency of the healthcare system. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource covid-19, healthcare cost, Financial model, ordered weighted average, <b>Keywords: f</b>uzzy logic Identifier An unambiguous reference to the resource within a given context 10.3390/math9040408 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Mathematics https://www.socictopen.socict.org/files/original/6146c2c7c4138ceef4f2e5c0f60b3ccf.pdf 3212be60b5e5bb9f28675687126afc7a Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource DARI TRADISIONAL MENUJU DIGITAL: ADOPSI INTERNET OLEH NAHDLATUL ULAMA SELAMA PANDEMI COVID-19 Creator An entity primarily responsible for making the resource Muhammad Irfan Wahid Description An account of the resource This article discussed on how religious organizations see and use the internet. The example of a case presented in this article was a mass organization of Nahdlatul Ulama. This article was based on assumption that Nahdlatul Ulama as a traditionalist religious organization tends to be conservative towards the development of information technology was an inaccurate analysis. The data in this article were obtained from Nahdlatul Ulama official website and literature. The findings indicated that despite having a traditionalist character, Nahdlatul Ulama was able to adopt internet technology as an information media for its religious worldviews. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Internet, digital, traditional, nahdlatul ulama Identifier An unambiguous reference to the resource within a given context 10.23971/jsam.v16i1.1745 Source A related resource from which the described resource is derived Jurnal Studi Agama dan Masyarakat Publisher An entity responsible for making the resource available LP2M IAIN Palangka Raya Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Islam https://www.socictopen.socict.org/files/original/6a47a80a709e5cda71503c09f6d77d92.pdf 2380f774d349b3c7d3d108eff2e5dbba Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Disease 2019 (COVID-19) in Children: Prevalence, Diagnosis, Clinical Symptoms, and Treatment Creator An entity primarily responsible for making the resource Zare-Zardini H, Soltaninejad H, Ferdosian F, Hamidieh AA, Memarpoor-Yazdi M Description An account of the resource Hadi Zare-Zardini,1,2 Hossein Soltaninejad,3 Farzad Ferdosian,4 Amir Ali Hamidieh,5 Mina Memarpoor-Yazdi6 1Department of Sciences, Farhangian University, Isfahan, Iran; 2Hematology and Oncology Research Center, Shahid Sadoughi Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran; 3Stem Cell and Regenerative Medicine Institute, Tehran University of Medical Sciences, Tehran, Iran; 4Department of Pediatrics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran; 5Pediatric Cell Therapy Research Center, Tehran University of Medical Sciences, Tehran, Iran; 6Faculty of Pharmacy, Mashhad University of Medical Sciences, Mashhad, IranCorrespondence: Mina Memarpoor-YazdiFaculty of Pharmacy, Mashhad University of Medical Sciences, Mashhad, IranEmail memarpooryazdi@gmail.comAbstract: In this article, we have reviewed the prevalence, diagnosis, symptoms, and treatment of COVID-19 in children. The incidence of COVID-19 among children under 18 years was 2.1% based on the reported studies, where the mortality rate in the same age group was 0.2%. No death has been reported in children under 9-years old. There are some articles that report children with COVID-19 having symptoms similar to Kawasaki&rsquo;s disease. In these cases, heart complications were observed. The best markers for diagnosing the severity of the disease in children are the levels of bilirubin and hepatic enzymes. Large number of angiotensin converting enzyme 2 (ACE2) receptors on cell surfaces, effective innate immune system, and high level of blood lymphocyte have been reported to be the potent reasons for lower incidence of severe symptoms of COVID-19 among children. Children can very well be the carriers of this virus. Children with severe COVID-19 clinical symptoms, especially those suffering from pneumonia, must be hospitalized similar to adults, while quarantine is required for those having mild symptoms. Antiviral medication (lopinavir, darunavir, favipiravir, remdesivir, ribavirin, oseltamivir, tocilizumab, and umifenovir), ACE inhibitors, interferon-&alpha; 2b, co-therapy with azithromycin, inhaling iNO, and oxygen therapy can be used for treatment. For the treatment of children without any clinical and infection symptoms, home isolation protocol has been recommended.Keywords: COVID-19, coronavirus, SARS-CoV-2, children, angiotensin converting enzyme 2, infectious Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource coronavirus, Children, covid-19, Infectious, SARS-CoV-2, angiotensin-converting enzyme 2 Source A related resource from which the described resource is derived Biotemas Publisher An entity responsible for making the resource available Universidade Federal de Santa Catarina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine (General) https://www.socictopen.socict.org/files/original/b57d7d300566f0a8585165a931282ae6.pdf 2dcb41d8375eb7018e4ae444607da288 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Palliative and end-of-life care in COVID-19 management in sub-Saharan Africa: a matter of concern. Creator An entity primarily responsible for making the resource Marie Josiane Ntsama Essomba, Laura Ciaffi, Paul Owono Etoundi, Agnès Esiene Description An account of the resource The COVID-19 pandemic has strained health care systems beyond capacity resulting in many people not having access to life-sustaining measures even in well-resourced countries. Palliative and end-of-life care are therefore essential to alleviate suffering and ensure a continuum of care for patients unlikely to survive. This is challenging in sub-Saharan Africa where lack of trained teams on basic palliative care and reduced access to opioids limit implementation of palliative and end-of-life care. At the same time, health care providers have to cope with local cultural conceptions of death and absence of advance care directives. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, palliative care, Sub-Saharan Africa Identifier An unambiguous reference to the resource within a given context 10.11604/pamj.supp.2020.35.130.25288 Source A related resource from which the described resource is derived The Pan African medical journal https://www.socictopen.socict.org/files/original/74193e4965c267dfc4ba76ebdd493b2b.pdf ce88097a43090570c59d578dea3b9c51 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Investigating People’s Anxieties and Concerns About COVID-19 Creator An entity primarily responsible for making the resource Mohammad Hossein Javadi, Soraya Sayar, Mohammad Sabzi Khoshnami, Sara Noruzi, Mahdokht Memaryan, Tahereh Azari Arghun, Farzaneh Yaghob, Zahra Afshari, Fatemeh Motiei Description An account of the resource Background: In January 2020, the World Health Organization (WHO) declared the COVID-19’s outbreak as an international public health emergency. In March 2020, WHO evaluation showed that COVID-19 could be considered a pandemic disease. Nowadays, the spread of COVID-19 threatens all aspects of human living conditions. In this regard, the objectives of this research are to investigate the anxieties and concerns of the Iranian people regarding the spread of COVID-19 in the initial months of its outbreak. Materials and Methods: This study was conducted with a qualitative methodology employing the conventional content analysis method. Data of anxieties and concerns of the general population were collected through social workers working at university/ medical schools throughout the country, affiliated healthcare centers, hotline 190, and social networks. The data collection process was saturated with 2920 theoretical data from February 27, 2020, to April 3, 2020. Results: Anxieties and concerns of community members were categorized into 8 areas: 1- Confusion in communication with the surrounding environment, 2- Concerns about vulnerable groups being affected, 3- The necessity of informational support, 4- Economic turmoil, 5- Shortage of preventive and treatment facilities, 6 -weakness of social capital, 7- Stressful and destructive atmosphere, 8- Approaches for crisis management situation. Conclusion: Based on the research findings, focusing and attention on people’s concerns in a transparent manner, and designing novel psychosocial support systems based on people’s real needs to control the disease spread result in the enhancement of social capital between community members to get through this crisis quickly. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, Concerns, anxietiy, psycosocia Source A related resource from which the described resource is derived Health in Emergencies & Disasters Quarterly Publisher An entity responsible for making the resource available Negah Institute for Scientific Communication Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medical emergencies. Critical care. Intensive care. First aid https://www.socictopen.socict.org/files/original/a67d06ff5b6e0397e97ec06bf8c0ef56.pdf 5ce4b437b934b5f2645623adf037bb0f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Aplicación de Machine Learning en la Indutria 4.0 en tiempos de pandemia Creator An entity primarily responsible for making the resource Romero Bravo, Guadalupe Janette, Espinoza Maza, Jonathan de Jesús, Macgluf Issasi, Arturo, Suárez Álvarez, Ángel, Rodríguez Rodríguez, Luis Alberto Description An account of the resource Los mayores crecimientos económicos vienen impulsados por grandes innovaciones tecnológicas. La industria, por su parte, trata de aprovechar estas revolucionarias tecnologías para crear nuevos modelos de negocio y generar altos beneficios con mínimo costo. Actualmente, nos encontramos en la cuarta revolución industrial, donde una de las tecnologías más importantes es la inteligencia artificial. En concreto, el aprendizaje automático o Machine Learning surge como un subcampo de la inteligencia artificial que da a las computadoras la habilidad de aprender sobre algo para lo que no han sido explícitamente programadas. Durante la reciente urgencia global, los científicos, médicos y expertos en atención médica de todo el mundo siguen buscando una nueva tecnología para ayudar a abordar la pandemia de Covid-19 y prevenir futuras pandemias. La evidencia de la aplicación de Machine Learning e Inteligencia Artificial en la epidemia alienta a los investigadores al brindar un nuevo ángulo para luchar contra el Coronavirus. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource covid-19, pandemia, Aprendizaje profundo, aprendizaje automático, Inteligência Artificial, tecnología, indústria 4.0, fábrica inteligente Identifier An unambiguous reference to the resource within a given context https://doi.org/10.25009/is.v0i11.2692 Source A related resource from which the described resource is derived Biotemas Publisher An entity responsible for making the resource available Universidade Federal de Santa Catarina Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Social history and conditions. Social problems. Social reform, Economic history and conditions https://www.socictopen.socict.org/files/original/cd7fcb3d391e9705f42cdd9ab3678021.pdf cd129fb0feab4b3f6a97f0610d9dc206 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The Impact of the Control Measures during the COVID-19 Outbreak on Air Pollution in China Creator An entity primarily responsible for making the resource Mona Allam, Ying Li, Cheng Fan, Jie Guang, Zhengqiang Li, Abdelrazek Elnashar, Gerrit de Leeuw Description An account of the resource The outbreak of the COVID-19 virus in Wuhan, China, in January 2020 just before the Spring Festival and subsequent country-wide measures to contain the virus, effectively resulted in the lock-down of the country. Most industries and businesses were closed, traffic was largely reduced, and people were restrained to their homes. This resulted in the reduction of emissions of trace gases and aerosols, the concentrations of which were strongly reduced in many cities around the country. Satellite imagery from the TROPOspheric Monitoring Instrument (TROPOMI) showed an enormous reduction of tropospheric NO2 concentrations, but aerosol optical depth (AOD), as a measure of the amount of aerosols, was less affected, likely due to the different formation mechanisms and the influence of meteorological factors. In this study, satellite data and ground-based observations were used together to estimate the separate effects of the Spring Festival and the COVID-19 containment measures on atmospheric composition in the winter of 2020. To achieve this, data were analyzed for a period from 30 days before to 60 days after the Spring Festivals in 2017–2020. This extended period of time, including similar periods in previous years, were selected to account for both the decreasing concentrations in response to air pollution control measures, and meteorological effects on concentrations of trace gases and aerosols. Satellite data from TROPOMI provided the spatial distributions over mainland China of the tropospheric vertical column density (VCD) of NO2, and VCD of SO2 and CO. The MODerate resolution Imaging Spectroradiometer (MODIS) provided the aerosol optical depth (AOD). The comparison of the satellite data for different periods showed a large reduction of, e.g., NO2 tropospheric VCDs due to the Spring Festival of up to 80% in some regions, and an additional reduction due to the COVID-19 containment measures of up to 70% in highly populated areas with intensive anthropogenic activities. In other areas, both effects are very small. Ground-based in situ observations from 26 provincial capitals provided concentrations of NO2, SO2, CO, O3, PM2.5, and PM10. The analysis of these data was focused on the situation in Wuhan, based on daily averaged concentrations. The NO2 concentrations started to decrease a few days before the Spring Festival and increased after about two weeks, except in 2020 when they continued to be low. SO2 concentrations behaved in a similar way, whereas CO, PM2.5, and PM10 also decreased during the Spring Festival but did not trace NO2 concentrations as SO2 did. As could be expected from atmospheric chemistry considerations, O3 concentrations increased. The analysis of the effects of the Spring Festival and the COVID-19 containment measures was complicated due to meteorological influences. Uncertainties contributing to the estimates of the different effects on the trace gas concentrations are discussed. The situation in Wuhan is compared with that in 26 provincial capitals based on 30-day averages for four years, showing different effects across China. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource covid-19, air pollution, spring festival Identifier An unambiguous reference to the resource within a given context 10.3390/rs12101613 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Science https://www.socictopen.socict.org/files/original/eb42e0d64d2cfbf2e6cb5bcc4a65572f.pdf bd8bda0b7f76262ff3a277c02c5a2436 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Transient oligomerization of the SARS-CoV N protein--implication for virus ribonucleoprotein packaging. Creator An entity primarily responsible for making the resource Chung-ke Chang, Chia-Min Michael Chen, Ming-hui Chiang, Yen-lan Hsu, Tai-huang Huang Description An account of the resource The nucleocapsid (N) phosphoprotein of the severe acute respiratory syndrome coronavirus (SARS-CoV) packages the viral genome into a helical ribonucleocapsid and plays a fundamental role during viral self-assembly. The N protein consists of two structural domains interspersed between intrinsically disordered regions and dimerizes through the C-terminal structural domain (CTD). A key activity of the protein is the ability to oligomerize during capsid formation by utilizing the dimer as a building block, but the structural and mechanistic bases of this activity are not well understood. By disulfide trapping technique we measured the amount of transient oligomers of N protein mutants with strategically located cysteine residues and showed that CTD acts as a primary transient oligomerization domain in solution. The data is consistent with the helical oligomer packing model of N protein observed in crystal. A systematic study of the oligomerization behavior revealed that altering the intermolecular electrostatic repulsion through changes in solution salt concentration or phosphorylation-mimicking mutations affects oligomerization propensity. We propose a biophysical mechanism where electrostatic repulsion acts as a switch to regulate N protein oligomerization. Date A point or period of time associated with an event in the lifecycle of the resource 2013 Identifier An unambiguous reference to the resource within a given context 10.1371/journal.pone.0065045 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Science, Medicine