1640 10 20655 https://www.socictopen.socict.org/files/original/8da3a56544464cda5088c3a37d8bec24.pdf 4360b1f61685387120b9a5dedafabacd Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Registro del atropellamiento de Herpailurus yagouarundi (Carnivora: Felidae) en la zona suburbana de Puerto Vallarta, México Creator An entity primarily responsible for making the resource Fabio Germán Cupul-Magaña Description An account of the resource Herpailurus yagouaroundi es uno de los felinos más atropellados en carretera de México. En esta nota, se presenta evidencia fotográfica de un jaguarundi arrollado en una carretera suburbana de Puerto Vallarta, México. Se comentan las características ambientales del sitio donde tuvo lugar el evento. Date A point or period of time associated with an event in the lifecycle of the resource 2019 Subject The topic of the resource Ecología de poblaciones, carretera, distribución, fauna arrollada, jaguarundi Identifier An unambiguous reference to the resource within a given context 10.47603/manovol5n2.16-19 Source A related resource from which the described resource is derived Mammalogy Notes Publisher An entity responsible for making the resource available Sociedad Colombiana de Mastozoología (SCMas) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Zoology Relation A related resource <a href="https://mammalogynotes.org/ojs/index.php/mn/article/view/127" target="_blank" rel="noreferrer noopener">https://mammalogynotes.org/ojs/index.php/mn/article/view/127</a> https://www.socictopen.socict.org/files/original/d9262aff7495ac22c7d3304cf47c5387.pdf 801310ded131f5a1cb4454ebe49488b5 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Registro fósil y distribución de Anadenathera en Argentina desde el Mioceno hasta la actualidad Creator An entity primarily responsible for making the resource L. Fernández-Pacella Description An account of the resource En la actualidad Fabaceae, es una de las familias dominantes de los Bosques Tropicales Estacionalmente Secos (Seasonally Dry Tropical Forests, SDNF o Bosques Secos Estacionales Neotropicales, BSEN. El género Anadenanthera, que integra dicha familia, tiene amplia distribución geográfica en el continente sudamericano y las Antillas, pero en Argentina sólo está presente Anadenantera colubrina var. cebil en el norte del país y sus registros están representados a partir del Mioceno Inferior hasta la actualidad por medio de palinomorfos y leños pemineralizados. El objetivo central de este trabajo es contribuir a la comprensión en el marco de la historia del género Anadenanthera durante el Neógeno y Cuaternario en Argentina, sobre la base de la revisión e integración de los antecedentes paleobotánicos, geológicos y climáticos disponibles que han afectado al género en el país. Los materiales fósiles estudiados provienen de diversas formaciones geológicas de Argentina: Formación Chenque (Mioceno Inferior), Formación Paraná (Mioceno Medio), Formación San José (Mioceno Medio), Formación Ituzaingó (Plioceno) y Esteros de Iberá (Holoceno). El material encontrado en la Formación Chenque es referido a Polyadopollenites coincide con el material descripto para el Mioceno Medio del centro-este de Argentina y para el Plioceno del noreste de Argentina. Por otra parte en la Formación Paraná e Ituzaingó se estudiaron ejemplares de leños permineralizados correspondientes a Anadenantheroxylon villaurquisense, por último, el ejemplar hallado en el Holoceno de los Esteros de Iberá en la provincia de Corrientes corresponde a Anadenanthera colubrina var. macrocarpa. Con estos datos se puede concluir que Anadenathera tuvo un registro geográfico amplio entre el Mioceno y Holoceno de Argentina, fue hallado en sedimentos del Mioceno Inferior de la Patagonia formando parte de una Paleoflora Subtropical. Desde el Mioceno Medio-Superior el género conformó parte de la vegetación del nordeste argentino constituyendo bosques xerófilos. Su último registro equivale al Holoceno Medio de sedimentos provenientes de los Esteros del Iberá, integrando la vegetación regional e indicando una vegetación abierta características de ambientes secos. Por último, es de destacar que la sucesión espacial y temporal del género Anadenanthera en la Argentina habría estado íntimamente asociada a los eventos tectónicos y climáticos acaecidos durante el Neógeno y Cuaternario. Date A point or period of time associated with an event in the lifecycle of the resource 2015 Subject The topic of the resource Anadenanthera, Argentina, Cambios Climáticos, Migración, registros fósiles Identifier An unambiguous reference to the resource within a given context 10.3989/egeol.41834.343 Source A related resource from which the described resource is derived Estudios Geologicos Publisher An entity responsible for making the resource available Consejo Superior de Investigaciones Científicas Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Geology Relation A related resource <a href="http://estudiosgeol.revistas.csic.es/index.php/estudiosgeol/article/view/925" target="_blank" rel="noreferrer noopener">http://estudiosgeol.revistas.csic.es/index.php/estudiosgeol/article/view/925</a> https://www.socictopen.socict.org/files/original/1d9bac38955457572fa487ee2e71fd69.pdf e0e9d9fbff2a1067ebb93c16a887febb Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Agricultura sostenible Description An account of the resource Dominio científico: Agricultura sostenible Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Regulador vegetal e bioestimulante na indução floral do maracujazeiro-amarelo em condições de entressafra Plant regulator and biostimulant in yellow passion-fruit floral induction under non inductive condition Creator An entity primarily responsible for making the resource Elma Machado Ataíde, Carlos Ruggiero, João Carlos de Oliveira, João Domingos Rodrigues, Teresinha de Jesus Déleo Rodrigues, José Rafael da Silva Description An account of the resource O objetivo do trabalho foi avaliar o efeito de regulador vegetal e de bioestimulante na indução floral do maracujazeiro-amarelo em condições não-indutivas, em Araguari-MG. Foram identificados e podados 12 ramos terciários por parcela (02-04-05), sendo 6 deles expostos de um lado da espaldeira, com luminosidade predominante pela manhã e 6 do outro lado da espaldeira, com luminosidade à tarde. O delineamento experimental foi em parcelas subdivididas, com 7 tratamentos principais (parcelas): 0mg L-1 (testemunha); 100mg L-1; 200mg L-1 e 300mg L-1 de regulador vegetal GA3 (i.a.); 2,08 mL L-1; 4,17mL L-1 e 6,25mL L-1 de bioestimulante Stimulate® (i.a.), em duas aplicações foliares (09-04-02 e 09-05-02), acrescidas de espalhante adesivo Silwett® a 0,05%. Além desses, foram utilizados 2 tratamentos secundários (subparcelas): exposição dos ramos à luminosidade da manhã e da tarde, com 4 repetições de 3 plantas por parcela. Cada subparcela foi um dos dois lados da espaldeira. As médias foram comparadas pelo teste de Tukey, a 5% de probabilidade. Realizou-se, aos 75 dias, a avaliação nos dois lados da espaldeira do comprimento dos ramos e entrenós, número de nós, de folhas e de botões florais. As variáveis estudadas não foram influenciadas pelo uso de GA3 e Stimulate®, no entanto houve diferença quando os ramos ficaram expostos à luminosidade da manhã em relação àqueles com luminosidade à tarde.The objective of the present work was to evaluate the effect of plant regulator and biostimulant in the floral induction of yellow passion-fruit under non inductive conditions in Araguari-MG. Twelve tertiary branches were identified and trimmed per plot (04/02/04), whereas six were exposed, on one side of the supporting stick, with predominant luminosity during the morning and six on the other side of the supporting stick, with luminosity during the evening. The experimental design was subdivided plots, with main treatments (plots): 0mg L-1 (control); 100mg L-1; 200mg L-1 and 300mg L-1 of plant regulator GA3 (i.a.); 2.08 mL L-1; 4,17mL L-1 and 6.25mL L-1 of StimulateTM biostimutant (i.a.), in two leaf applications (04/09/02 e 05/09/02), supplemented with SilwettTM adhesive spread at 0.05%. Besides those treatments, secondary treatments were used (subplots): exposition of the branches to morning and evening light, with four repetitions and three plants per plot. Each subplot was one of the sides of the supporting stick. The data was submitted to the analysis of variance. In both sides of the supporting stick, the length of the branches and internodes, the numbers of nodes, of leaves and of floral buds were evaluated at 75 days after the first application of the treatments. The variables studied were not influenced by the use of GA3 and StimulateTM, however, there was difference when the branches were exposed to morning light in relationship to those exposed to evening light. Date A point or period of time associated with an event in the lifecycle of the resource 2006 Subject The topic of the resource Giberelina, Passiflora edulis Sims f. flavicarpa, Stimulate, florescimento, flowering, gibberelin Identifier An unambiguous reference to the resource within a given context 10.1590/S0100-29452006000300003 Source A related resource from which the described resource is derived Revista Brasileira de Fruticultura Publisher An entity responsible for making the resource available Sociedade Brasileira de Fruticultura Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Plant culture Relation A related resource <a href="http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-29452006000300003" target="_blank" rel="noreferrer noopener">http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-29452006000300003</a> https://www.socictopen.socict.org/files/original/29a57fa3a7efa0cd512bcdb53168fc54.pdf 2d71ee305fdd6f8b7cea6b27b27fe2cc Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Regulation of coronaviral poly(A) tail length during infection. Creator An entity primarily responsible for making the resource Hung-Yi Wu, Ting-Yung Ke, Wei-Yu Liao, Nai-Yun Chang Description An account of the resource The positive-strand coronavirus genome of ~30 kilobase in length and subgenomic (sg) mRNAs of shorter lengths, are 5' and 3'-co-terminal by virtue of a common 5'-capped leader and a common 3'-polyadenylated untranslated region. Here, by ligating head-to-tail viral RNAs from bovine coronavirus-infected cells and sequencing across the ligated junctions, it was learned that at the time of peak viral RNA synthesis [6 hours postinfection (hpi)] the 3' poly(A) tail on genomic and sgmRNAs is ~65 nucleotides (nt) in length. Surprisingly, this length was found to vary throughout infection from ~45 nt immediately after virus entry (at 0 to 4 hpi) to ~65 nt later on (at 6 h to 9 hpi) and from ~65 nt (at 6 h to 9 hpi) to ~30 nt (at 120-144 hpi). With the same method, poly(U) sequences of the same lengths were simultaneously found on the ligated viral negative-strand RNAs. Functional analyses of poly(A) tail length on specific viral RNA species, furthermore, revealed that translation, in vivo, of RNAs with the longer poly(A) tail was enhanced over those with the shorter poly(A). Although the mechanisms by which the tail lengths vary is unknown, experimental results together suggest that the length of the poly(A) and poly(U) tails is regulated. One potential function of regulated poly(A) tail length might be that for the coronavirus genome a longer poly(A) favors translation. The regulation of coronavirus translation by poly(A) tail length resembles that during embryonal development suggesting there may be mechanistic parallels. Date A point or period of time associated with an event in the lifecycle of the resource 2013 Identifier An unambiguous reference to the resource within a given context DOI: 10.1371/journal.pone.0070548 Source A related resource from which the described resource is derived PLoS ONE Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Science, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/00f4f5e487e03b6a7eb70ea711e904d2.pdf 7947121d0f96624996720b3284e555d6 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Regulation of programmed ribosomal frameshifting by co-translational refolding RNA hairpins. Creator An entity primarily responsible for making the resource Che-Pei Cho, Szu-Chieh Lin, Ming-Yuan Chou, Hsiu-Ting Hsu, Kung-Yao Chang Description An account of the resource RNA structures are unwound for decoding. In the process, they can pause the elongating ribosome for regulation. An example is the stimulation of -1 programmed ribosomal frameshifting, leading to 3' direction slippage of the reading-frame during elongation, by specific pseudoknot stimulators downstream of the frameshifting site. By investigating a recently identified regulatory element upstream of the SARS coronavirus (SARS-CoV) -1 frameshifting site, it is shown that a minimal functional element with hairpin forming potential is sufficient to down-regulate-1 frameshifting activity. Mutagenesis to disrupt or restore base pairs in the potential hairpin stem reveals that base-pair formation is required for-1 frameshifting attenuation in vitro and in 293T cells. The attenuation efficiency of a hairpin is determined by its stability and proximity to the frameshifting site; however, it is insensitive to E site sequence variation. Additionally, using a dual luciferase assay, it can be shown that a hairpin stimulated +1 frameshifting when placed upstream of a +1 shifty site in yeast. The investigations indicate that the hairpin is indeed a cis-acting programmed reading-frame switch modulator. This result provides insight into mechanisms governing-1 frameshifting stimulation and attenuation. Since the upstream hairpin is unwound (by a marching ribosome) before the downstream stimulator, this study's findings suggest a new mode of translational regulation that is mediated by the reformed stem of a ribosomal unwound RNA hairpin during elongation. Date A point or period of time associated with an event in the lifecycle of the resource 2013 Identifier An unambiguous reference to the resource within a given context DOI: 10.1371/journal.pone.0062283 Source A related resource from which the described resource is derived PLoS ONE Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Science, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/514e047cf77ca5751be38abf612bdda5.pdf fb8a04707e757a3e2316d0cfef755d4f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Regulation of Stress Responses and Translational Control by Coronavirus Creator An entity primarily responsible for making the resource To Sing Fung, Ying Liao, Ding Xiang Liu Description An account of the resource Similar to other viruses, coronavirus infection triggers cellular stress responses in infected host cells. The close association of coronavirus replication with the endoplasmic reticulum (ER) results in the ER stress responses, which impose a challenge to the viruses. Viruses, in turn, have come up with various mechanisms to block or subvert these responses. One of the ER stress responses is inhibition of the global protein synthesis to reduce the amount of unfolded proteins inside the ER lumen. Viruses have evolved the capacity to overcome the protein translation shutoff to ensure viral protein production. Here, we review the strategies exploited by coronavirus to modulate cellular stress response pathways. The involvement of coronavirus-induced stress responses and translational control in viral pathogenesis will also be briefly discussed. Date A point or period of time associated with an event in the lifecycle of the resource 2016 Subject The topic of the resource coronavirus, ER stress, Unfolded Protein Response, p38, JNK, eIF2α, PKR, p-ERK, GADD34/PP1, nsp1, translational control Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/v8070184 Source A related resource from which the described resource is derived Viruses Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology Language A language of the resource EN https://www.socictopen.socict.org/files/original/dc893d248acb00bc24016f55771d6e12.pdf 663265af696621d64f2d24f2c9570a6b Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Regulation of the ER Stress Response by the Ion Channel Activity of the Infectious Bronchitis Coronavirus Envelope Protein Modulates Virion Release, Apoptosis, Viral Fitness, and Pathogenesis Creator An entity primarily responsible for making the resource Shu-Min Li, Li-xia Yuan, Guo Dai, Ruiai Chen, Ding Xiang Liu, To Sing Fung Description An account of the resource Coronavirus (CoV) envelope (E) protein is a small structural protein critical for virion morphogenesis and release. The recently characterized E protein ion channel activity (EIC) has also been implicated in modulating viral pathogenesis. In this study, we used infectious bronchitis coronavirus (IBV) as a model to study EIC. Two recombinant IBVs (rIBVs) harboring EIC-inactivating mutations – rT16A and rA26F – were serially passaged, and several compensatory mutations were identified in the transmembrane domain (TMD). Two rIBVs harboring these putative EIC-reverting mutations – rT16A/A26V and rA26F/F14N – were recovered. Compared with the parental rIBV-p65 control, all four EIC mutants exhibited comparable levels of intracellular RNA synthesis, structural protein production, and virion assembly. Our results showed that the IBV EIC contributed to the induction of ER stress response, as up-regulation of ER stress-related genes was markedly reduced in cells infected with the EIC-defective mutants. EIC-defective mutants also formed smaller plaques, released significantly less infectious virions into the culture supernatant, and had lower levels of viral fitness in cell culture. Significantly, all these defective phenotypes were restored in cells infected with the putative EIC revertants. EIC mutations were also implicated in regulating IBV-induced apoptosis, induction of pro-inflammatory cytokines, and viral pathogenicity in vivo. Taken together, this study highlights the importance of CoV EIC in modulating virion release and various aspects of CoV – host interaction. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource coronavirus, Viroporin, ion channel activity, ER stress response, proinflammatory cytokine, pathogenesis Identifier An unambiguous reference to the resource within a given context DOI: 10.3389/fmicb.2019.03022 Source A related resource from which the described resource is derived Frontiers in Microbiology Publisher An entity responsible for making the resource available Frontiers Media S.A. Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology Language A language of the resource EN https://www.socictopen.socict.org/files/original/e989f6b50fb805bf6e31f50faeed2c9b.pdf 573c867045a2a17980ddeb48dd3ae727 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Regulatory Cross Talk Between SARS-CoV-2 Receptor Binding and Replication Machinery in the Human Host Creator An entity primarily responsible for making the resource Shiek S. S. J. Ahmed, Prabu Paramasivam, Prabu Paramasivam, Kamal Raj, Vishal Kumar, Ram Murugesan, V. Ramakrishnan Description An account of the resource We dissect the mechanism of SARS-CoV-2 in human lung host from the initial phase of receptor binding to viral replication machinery. Two independent lung protein interactome were constructed to reveal the signaling process on receptor activation and host protein hijacking machinery in the pathogenesis of virus. Further, we test the functional role of the hubs derived from the interactome. Most hubs proteins were differentially regulated on SARS-CoV-2 infection. Also, the proteins in viral replication hubs were related with cardiovascular disease, diabetes and hypertension confirming the vulnerability and severity of infection in the risk individual. Additionally, the hub proteins were closely linked with other viral infection, including MERS and HCoVs which suggest similar infection pattern in SARS-CoV-2. We identified five hubs that interconnect both networks that show the preparation of optimal environment in the host for viral replication process upon receptor attachment. Interestingly, we propose that seven potential miRNAs, targeting the intermediate phase that connects receptor and viral replication process a better choice as a drug for SARS-CoV-2. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource systems biology, covid-19, SARS-CoV-2, transcriptome, miRNA targets, host mechanism Identifier An unambiguous reference to the resource within a given context 10.3389/fphys.2020.00802 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Physiology https://www.socictopen.socict.org/files/original/50901a9a08755a1914a4de221e222240.pdf 592b900ea47ef1006ffc15e2ca840e45 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Regulatory T Cells in Arterivirus and Coronavirus Infections: Do They Protect Against Disease or Enhance it? Creator An entity primarily responsible for making the resource Tanya LeRoith, S. Michelle Todd, Thomas E. Cecere Description An account of the resource Regulatory T cells (Tregs) are a subset of T cells that are responsible for maintaining peripheral immune tolerance and homeostasis. The hallmark of Tregs is the expression of the forkhead box P3 (FoxP3) transcription factor. Natural regulatory T cells (nTregs) are a distinct population of T cells that express CD4 and FoxP3. nTregs develop in the thymus and function in maintaining peripheral immune tolerance. Other CD4+, CD4-CD8-, and CD8+CD28- T cells can be induced to acquire regulatory function by antigenic stimulation, depending on the cytokine milieu. Inducible (or adaptive) Tregs frequently express high levels of the interleukin 2 receptor (CD25). Atypical Tregs express FoxP3 and CD4 but have no surface expression of CD25. Type 1 regulatory T cells (Tr1 cells) produce IL-10, while T helper 3 cells (Th3) produce TGF-β. The function of inducible Tregs is presumably to maintain immune homeostasis, especially in the context of chronic inflammation or infection. Induction of Tregs in coronaviral infections protects against the more severe forms of the disease attributable to the host response. However, arteriviruses have exploited these T cell subsets as a means to dampen the immune response allowing for viral persistence. Treg induction or activation in the pathogenesis of disease has been described in both porcine reproductive and respiratory syndrome virus, lactate dehydrogenase elevating virus, and mouse hepatitis virus. This review discusses the development and biology of regulatory T cells in the context of arteriviral and coronaviral infection. Date A point or period of time associated with an event in the lifecycle of the resource 2012 Subject The topic of the resource regulatory T cell, arterivirus, porcine reproductive and respiratory syndrome virus, lactate dehydrogenase-elevating virus, coronavirus Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/v4050833 Source A related resource from which the described resource is derived Viruses Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology Language A language of the resource EN https://www.socictopen.socict.org/files/original/9d064edc31bf343385b22a9234f4caeb.pdf f8d68941b588433a748336d44b863599 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource REIMAGINAÇÕES CRÍTICAS DA POLÍTICA E DA HISTÓRIA NO ANIME “PATRULHA ESTELAR”, DE LEIJI MATSUMOTO Creator An entity primarily responsible for making the resource Luis Mauro Sá Martino Description An account of the resource Este artigo delieneia algumas das representações de história e da política no anime Uchuu Senkan Yamato, exibido pela primeira vez em 1977, e no Brasil, na década de 1980 pela TV Manchete, como “Patrulha Estelar”. O anime narra as aventuras do navio japonês Yamato, destruído na 2a. Guerra, transformado, no século 23, em uma nave espacial para salvar a Terra de ameaças alienígenas. A análise narrativa dos 77 episódios do anime sugere que o tratamento de questões históricas e políticas acontece de duas maneiras: (1) uma reinterpretação imaginativa da História, particularmente da 2a. Guerra, com o Yamato se juntando ao lado dos “aliados”; (2) uma crítica ao consumismo e materialismo, bem como ao militarismo, mostrados em oposição a valores como amizade e entendimento. Esses pontos são discutidos a partir dos estudos recentes sobre entretenimento e política. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource coronavirus, fact-checking, jornalismo Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Visual arts