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                  <text>Dominio científico: Coronavirus</text>
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                <text>Particulate Matter and COVID-19 Disease Diffusion in Emilia-Romagna (Italy). Already a Cold Case?</text>
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                <text>Marco Roccetti, Silvia Mirri, Giovanni Delnevo</text>
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                <text>As we prepare to emerge from an extensive and unprecedented lockdown period, due to the COVID-19 virus infection that hit the Northern regions of Italy with the Europe’s highest death toll, it becomes clear that what has gone wrong rests upon a combination of demographic, healthcare, political, business, organizational, and climatic factors that are out of our scientific scope. Nonetheless, looking at this problem from a patient’s perspective, it is indisputable that risk factors, considered as associated with the development of the virus disease, include older age, history of smoking, hypertension and heart disease. While several studies have already shown that many of these diseases can also be favored by a protracted exposure to air pollution, there has been recently an insurgence of negative commentary against authors who have correlated the fatal consequences of COVID-19 (also) to the exposition of specific air pollutants. Well aware that understanding the real connection between the spread of this fatal virus and air pollutants would require many other investigations at a level appropriate to the scale of this phenomenon (e.g., biological, chemical, and physical), we propose the results of a study, where a series of the measures of the daily values of PM2.5, PM10, and NO2 were considered over time, while the Granger causality statistical hypothesis test was used for determining the presence of a possible correlation with the series of the new daily COVID19 infections, in the period February–April 2020, in Emilia-Romagna. Results taken both before and after the governmental lockdown decisions show a clear correlation, although strictly seen from a Granger causality perspective. Moving beyond the relevance of our results towards the real extent of such a correlation, our scientific efforts aim at reinvigorating the debate on a relevant case, that should not remain unsolved or no longer investigated.</text>
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                <text>air pollution, correlation, granger causality, time series, Emilia-Romagna, COVID-19</text>
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                <text>DOI: 10.3390/computation8020059</text>
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                <text>Electronic computers. Computer science</text>
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                <text>Targeting the Immune System for Pulmonary Inflammation and Cardiovascular Complications in COVID-19 Patients</text>
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                <text>Serena Colafrancesco, Roberta Priori, Rossana Scrivo, Cristiana Barbati, Fabrizio Conti</text>
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                <text>In December 2019, following a cluster of pneumonia cases in China caused by a novel coronavirus (CoV), named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the infection disseminated worldwide and, on March 11th, 2020, the World Health Organization officially declared the pandemic of the relevant disease named coronavirus disease 2019 (COVID-19). In Europe, Italy was the first country facing a true health policy emergency, and, as at 6.00 p.m. on May 2nd, 2020, there have been more than 209,300 confirmed cases of COVID-19. Due to the increasing number of patients experiencing a severe outcome, global scientific efforts are ongoing to find the most appropriate treatment. The usefulness of specific anti-rheumatic drugs came out as a promising treatment option together with antiviral drugs, anticoagulants, and symptomatic and respiratory support. For this reason, we feel a duty to share our experience and our knowledge on the use of these drugs in the immune-rheumatologic field, providing in this review the rationale for their use in the COVID-19 pandemic.</text>
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                <text>Interleukin-6, ARDS, hydroxychloroquine, Interleukin-1, JAK inhibitors, COVID-19</text>
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                <text>DOI: 10.3389/fimmu.2020.01439</text>
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                <text>Frontiers in Immunology</text>
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                <text>Frontiers Media S.A.</text>
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                <text>Immunologic diseases. Allergy</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>COVID-19's Impact on the Innovation Development of Economies of Ukraine and Poland: Current Status and Prospects</text>
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                <text>Zalizko Vasyl D., Mykula Ruslan V., Nowak Dariusz Wojciech, Kukhta Pavlo V.</text>
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                <text>The article systematizes the experience in identifying and assessing the impact of epidemics and viruses on the development of national economies. It is proposed, to strengthen the national economy of Ukraine, to mobilize internal potential of light industry for activating the domestic manufacturers of personal protective equipment. The example of Poland and Ukraine showed a negative impact of COVID-19 on the innovative development of their national economies and outlined the prospects for the development of modern technology telecommuting in the most sectors of the national economy and education. As a result of the coronavirus COVID-19 epidemic, a logistical collapse took place, production processes stopped for an indefinite period, the financial and economic crisis was provoked, and the innovative development of national economies was slowed down. The whole world has to mobilize human and financial resources to counter the spread of this disease. Poland and Ukraine have already taken a number of serious steps to minimize the impact of the coronavirus COVID-19 on both economic and social life. According to the authors of the article, minimization of the impact of COVID-19 on the economy of Poland and Ukraine is possible only by introducing modern technologies of telecommuting in most sectors of the national economy and education. Following the scientific thought and joint research of the Poznan University of Economics and the International Innovation Center in the framework of the formation of the «Central European Network of Continuous and Innovative Economy», the new Prime Minister of Ukraine D. Shmygal approved an enhanced plan to combat the spread of the coronavirus COVID-19 in Ukraine, which provides mobilization of the domestic potential of light industry for the activation of domestic manufacturers of personal protective equipment in the framework of implementing the law on economic competition and the protection of the rights of patients in the retail trade with protective equipment.</text>
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                <text>2020</text>
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                <text>Globalization, Poland, global economy, Ukraine, innovative development, coronavirus covid-19</text>
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                <text>DOI: 10.32983/2222-4459-2020-4-79-87</text>
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                <text>Bìznes Inform</text>
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                <text>Research Centre of Industrial Problems of Development of NAS of Ukraine</text>
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                <text>Business</text>
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                <text>Epidemiological Determinants of Acute Respiratory Syndrome Coronavirus-2 Disease Pandemic and The Role of the Bacille-Calmette-Guerin Vaccine in Reducing Morbidity and Mortality</text>
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                <text>Kuldeep Dhama, Bhoj R. Singh, Dharmender Kumar, Dharmendra K. Sinha, R. Karthikeyan, Shiv Varan Singh, Akanksha Yadav, Vinodh Kumar O.R., Richa Gandharva, Varsha Jayakumar, Sumedha Gandharava</text>
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                <text>This study analyzed the determinants of morbidity, mortality, and case fatality rate (CFR) of the ongoingpandemic of severe acute respiratory syndrome coronavirus-2 disease 2019 (COVID-19). Data for 210countries and territories available in public domains were analyzed in relation to mandatory vaccinationwith Bacille-Calmette-Guerin (BCG), population density, median age of the country population, healthcare expenditure per capita, life expectancy at birth, healthy life expectancy, literacy rate, per capitagross domestic production adjusted to purchasing power (PPP), burden of tuberculosis (TB), acquiredimmunodeficiency disease caused by human immunodeficiency virus (HIV-AIDS), malaria, cardiovasculardisease (CVD), neoplasm, diabetes, deaths due to energy-protein (food) deficiency (EPD), and percapita government spending on safe water and sanitation. Mandatory BCG vaccination showed ahighly significant (p</text>
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                <text>2020</text>
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                <text>effectors, Epidemiology, poverty, BCG vaccine, PPP, TB, CVD, SARS-CoV-2, COVID-19</text>
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                <text>DOI: 10.22207/JPAM.14.SPL1.39</text>
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                <text>Journal of Pure and Applied Microbiology</text>
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                <text>Microbiology</text>
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                <text>On a Coupled Time-Dependent SIR Models Fitting with New York and New-Jersey States COVID-19 Data</text>
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              <elementText elementTextId="38275">
                <text>M. A. Aziz-Alaoui, Benjamin Ambrosio</text>
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                <text>This article describes a simple Susceptible Infected Recovered (SIR) model fitting with COVID-19 data for the month of March 2020 in New York (NY) state. The model is a classical SIR, but is non-autonomous; the rate of susceptible people becoming infected is adjusted over time in order to fit the available data. The death rate is also secondarily adjusted. Our fitting is made under the assumption that due to limiting number of tests, a large part of the infected population has not been tested positive. In the last part, we extend the model to take into account the daily fluxes between New Jersey (NJ) and NY states and fit the data for both states. Our simple model fits the available data, and illustrates typical dynamics of the disease: exponential increase, apex and decrease. The model highlights a decrease in the transmission rate over the period which gives a quantitative illustration about how lockdown policies reduce the spread of the pandemic. The coupled model with NY and NJ states shows a wave in NJ following the NY wave, illustrating the mechanism of spread from one attractive hot spot to its neighbor.</text>
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                <text>2020</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>Network, New Jersey, New York, SIR models, COVID-19</text>
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              <elementText elementTextId="38279">
                <text>DOI: 10.3390/biology9060135</text>
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            <description>A related resource from which the described resource is derived</description>
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                <text>Biology</text>
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            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="38281">
                <text>MDPI AG</text>
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            </elementTextContainer>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="38282">
                <text>Biology (General)</text>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                <elementText elementTextId="1">
                  <text>Coronavirus</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
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        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="38265">
                <text>Convalescent Plasma Coupled With Medications for the Treatment of a Severe COVID-19 Patient: Drugs Analysis and Pharmaceutical Care Based on the Newly Established Guidelines for COVID-19 Remedy</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="38266">
                <text>Yang Zhang, Ying Wang, Qian Yu, Kun Zhu</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>Given the extreme importance of the current pandemic caused by COVID-19 and due to the fact that scientists agree that there is no identified treatment, this paper analyzes in detail the treatment of a severe COVID-19 patient with convalescent plasma and drugs based on current guidelines for COVID-19 diagnosis and treatment. This can provide a reference for other medical institutions on rational drug use and pharmaceutical care for severe COVID-19 patients.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="38268">
                <text>2020</text>
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            </elementTextContainer>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="38269">
                <text>guideline, therapeutic strategy, convalescent plasma, drugs analysis, COVID-19 (severe)</text>
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            </elementTextContainer>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="38270">
                <text>DOI: 10.3389/fphar.2020.00966</text>
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            </elementTextContainer>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="38271">
                <text>Frontiers in Pharmacology</text>
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            </elementTextContainer>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="38272">
                <text>Frontiers Media S.A.</text>
              </elementText>
            </elementTextContainer>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="38273">
                <text>Therapeutics. Pharmacology</text>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                <elementText elementTextId="1">
                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="38256">
                <text>100 Days of COVID-19 in India: Current and Future Trends</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="38257">
                <text>Sheetal Gouda, G. Naveen, F. Sneha Kukanur</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="38258">
                <text>COVID-19 classified under emerging infectious diseases has spread across the world resulting inmany casualties. India reported its first case on 30th January 2020 and has completed 100 days in thispandemic period. The government of India has issued stringent guidelines and imposed a lockdown forlong periods to ensure the practising of social distancing. This paper reviews and discusses the currenttrends in the confirmed cases of India in comparison with the other prominent countries around theglobe. A novel approach using a sigmoid function to predict and forecast the trends for cases in Indiaare also presented in this work. By placing the current time on the sigmoid curve, forecasting the totalnumber of confirmed cases by the end of the pandemic is made. If proper measures and stringentguidelines are not followed, India may have to endure a total confirmed case of up to 4.4 lakh. Theprediction also suggests that 99.9% of the pandemic may end in India by 27th July 2020. The best possibleapproach is to undertake preventive measures by strictly adhering to the guidelines and policies setby the government. Performing hand hygiene, practicing social distancing, surveillance and isolationis the only means to break the chain of transmission and control the pandemic.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="38259">
                <text>2020</text>
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            </elementTextContainer>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="38260">
                <text>forecasting, India, coronavirus, Sigmoid, COVID-19</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="38261">
                <text>DOI: 10.22207/JPAM.14.SPL1.43</text>
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            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="38262">
                <text>Journal of Pure and Applied Microbiology</text>
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          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="38263">
                <text>Journal of Pure and Applied Microbiology</text>
              </elementText>
            </elementTextContainer>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="38264">
                <text>Microbiology</text>
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  <item itemId="4186" public="1" featured="0">
    <fileContainer>
      <file fileId="4186">
        <src>https://www.socictopen.socict.org/files/original/48eafa8467e7b0c6df1dfed7805f7e78.pdf</src>
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          <name>Dublin Core</name>
          <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
          <elementContainer>
            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
              <elementTextContainer>
                <elementText elementTextId="1">
                  <text>Coronavirus</text>
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              </elementTextContainer>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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    <itemType itemTypeId="1">
      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
        <elementContainer>
          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="38247">
                <text>Pharmacotherapics Advice in Guidelines for COVID-19</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="38248">
                <text>Jin Liu, Jian Zhou, Ying Zhou, Lili Liu, Xiaohua Wei, Jinhua Wen, Zhangren Chen, Hongwei Peng, Haili Zhong, Ming-Fang Lai</text>
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          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="38249">
                <text>Since December 2019 to May 2020, coronavirus disease 2019 (COVID-19) has infected over 6 million people worldwide. Due to its sudden and rapid outbreak, effective treatment for COVID-19 is scarce. Based on national clinical trials of novel treatments, China, Italy, Germany, and other countries and organizations have published multiple guidelines for COVID-19 and advised many medicines, such as chloroquine and tocilizumab. In this paper, we summarize the pharmacotherapy for COVID-19 according to those guidelines, highlight updates of the pharmacotherapy guidelines, and review the efficacy and safety of the indicated anti-COVID-19 drugs.</text>
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          <element elementId="40">
            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="38250">
                <text>2020</text>
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            </elementTextContainer>
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          <element elementId="49">
            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="38251">
                <text>Pneumonia, Pharmacotherapy, guideline, SARS-CoV-2, COVID-19</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="38252">
                <text>DOI: 10.3389/fphar.2020.00950</text>
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            </elementTextContainer>
          </element>
          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="38253">
                <text>Frontiers in Pharmacology</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="38254">
                <text>Frontiers Media S.A.</text>
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          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="38255">
                <text>Therapeutics. Pharmacology</text>
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  <item itemId="4185" public="1" featured="0">
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        <src>https://www.socictopen.socict.org/files/original/096f636586cb264bb310e38c6fc18bf6.pdf</src>
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                <elementText elementTextId="1">
                  <text>Coronavirus</text>
                </elementText>
              </elementTextContainer>
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            <element elementId="41">
              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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    <itemType itemTypeId="1">
      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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              <elementText elementTextId="38238">
                <text>Building Resilient Urban Communities: The Case Study of Setubal Municipality, Portugal</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="38239">
                <text>Nuno Sousa, Ângela Santos, José Luís Bucho, Horst Kremers</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="38240">
                <text>The Sendai Framework for Disaster Risk Reduction provides several guidelines that countries should follow. Still, some scientific papers discussed the limitations, difficulties, and strategies in the implementation of these guidelines. Therefore, the objective of this review is to understand what Setubal has done to cope with disasters, and the practical strategies to mitigate them. To achieve this, several methodological guidelines and Portuguese legal documents were analyzed. The results focus on the top four natural disasters that impacted the study area (landslides, earthquakes, tsunamis, and floods), and the current pandemic of COVID-19. The practical strategies implemented on the territory involve the installation of equipment such as emergency signs and electronic panels that allow the dissemination of information to the communities in real-time. Also, the collaboration with national and international scientists provided new insight to cope with disasters, by bridging the gap between law enforcement agencies, science, first responders, and the practical needs that local stakeholders must solve on the territory. Moreover, Setubal has implemented a variety of practical and innovative measures, and therefore, could be used as a model not only to other Portuguese municipalities but also to other countries.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
            <elementTextContainer>
              <elementText elementTextId="38241">
                <text>2020</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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              <elementText elementTextId="38242">
                <text>flood, prevention, earthquake, tsunami, landslide, mitigation of risks</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
            <elementTextContainer>
              <elementText elementTextId="38243">
                <text>DOI: 10.3390/geosciences10060243</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="38244">
                <text>Geosciences</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="38245">
                <text>MDPI AG</text>
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            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="38246">
                <text>Geology</text>
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  <item itemId="4184" public="1" featured="0">
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                <text>The COVID-19 caused by a new type of coronavirus has emerged from China and led to thousands ofdeath globally. Despite the efforts engaged in studying this newly emerged virus and searching for itstreatment, the understanding of the COVID-19 drug and target protein interactions still represent a keychallenge. Several molecules have demonstrated In-Vitro activity against the SARS-CoV-2 virus and/or potential clinical benefit in observational and non-randomized studies. Randomized clinical trialsof an appropriate size are currently ongoing to establish the efficacy of these therapeutic proposals.Herein, concerning these diverse guidelines and therapeutic suggestions of different approaches to thetreatment, this research aims to provide a molecular analysis of the interaction between the principalmolecules cited in bibliography and the active protease site of the virus.</text>
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