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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>The role of the urban settlement system in the spread of Covid-19 pandemic. The Italian case</text>
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                <text>Rocco Papa, Gerardo Carpentieri, Floriana Zucaro, Carmela Gargiulo, Federica Gaglione, Carmen Guida</text>
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                <text>The paper proposes a focus on three main aspects related to the spread of the new coronavirus in our country: the correlations that have been established between the spread of the Covid-19 virus and the settlement system of our country; the urban and territorial phenomena that can be associated, positively or negatively, with the diffusion of the virus; and, finally, the correspondence between homogeneous clusters of Italian provinces (due to the current most significant urban phenomena) and the intensity and spread of the infection. The research is divided in four steps: the identification of the scientific and disciplinary approach, the definition of territorial areas and their descriptive variables, the choice of computational models, and the evaluation of the results. The main findings of the study highlight that significant correlations are not always identifiable between settlement characteristics and the spread of the infection. The diffusion of the new coronavirus is closely related to some of the main features of the demographic (e.g. people aged 65 years and above) and socio-economic (e.g. GDP for inhabitant) structure of the urban population.</text>
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                <text>2020</text>
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                <text>holistic approach, statistic analysis, settlement system, spread of covid-19 virus</text>
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                <text>DOI: 10.6092/1970-9870/6864</text>
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                <text>TeMA: Journal of Land Use, Mobility and Environment</text>
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                <text>Università di Napoli Federico II</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Transportation engineering, Urbanization. City and country</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>About the Sustainability of Urban Settlements</text>
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                <text>Maurizio Tira</text>
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                <text>Urbanization is an onerous human activity: it affects municipal budget and foremost it costs the environment. Nevertheless, an ever-growing number of people (more than 75% of the European population) is living in cities and towns, so that identifying sustainable urban development solutions is a dramatically urgent need. Already in the 70s, some researches proposed parameters to evaluate urbanization costs in Italy, but they mainly focused on the economic and financial sustainability of real estate development. The land value capturing approaches proved to be inadequate when municipal budgets are facing growing social unbalances and critical environmental threats. The question being not just “where the money for urban infrastructures could come from”, but also “what could be a more sustainable development model”. In any case, now we are forced to rethink the whole organization of our urban life to defend ourselves from largely unknown threats, pandemics, COVID-19 being probably one among others that we could face in the near future. It is not yet clear if a link exists between the spread of the virus, the health consequences and the environmental conditions, but what probably will need to be assessed is the effect of population density on the spread of contamination. Even the traditional provision of services and public spaces will need to be defined again in order to protect and serve urban population. New evidences will force planners to redefine their thoughts and schemes.</text>
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                <text>2020</text>
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                <text>sustainability, urban development, Pandemic</text>
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                <text>DOI: 10.6092/1970-9870/6984</text>
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                <text>TeMA: Journal of Land Use, Mobility and Environment</text>
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                <text>Università di Napoli Federico II</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Transportation engineering, Urbanization. City and country</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>How Close are We to a COVID-19 Vaccine?</text>
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                <text>Kayhan Ozkan</text>
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                <text>This review provides an overview regarding the main aspects of candidate COVID-19 vaccines andpathophysiology of disease. The types of biotechnological candidate vaccines to be developedagainst COVID-19, their degree of protection and the pathophysiological mechanism of the diseasewere analyzed in this review article. The literature data on which cruxes for the development ofbiotechnological candidate vaccines to be wended are based was researched. Data that could givereference to various biotechnological candidate vaccines were reviewed. For this purpose, up-todate literature data was utilized. The ways to succeed in the development of a vaccine requiring atechnological infrastructure are to synthesize the data obtained from long term trials and to put theminto practice subsequently. The vaccines to be developed by means of recombinant DNA technology willbe a source of inspiration to people for further studies. After a rapid process of vaccine development,the use of COVID-19 vaccine can be mainstreamed among people to prevent the disease. As a resultof these practices, the evaluation of which vaccine will be more safe, reliable and effective will beperformed after phase studies.</text>
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              <elementText elementTextId="36623">
                <text>2020</text>
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            <name>Subject</name>
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                <text>immune response, Recombinant, COVID-19 vaccine, atteneu virus, phase studies</text>
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                <text>DOI: 10.22207/JPAM.14.SPL1.26</text>
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              <elementText elementTextId="36626">
                <text>Journal of Pure and Applied Microbiology</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="36627">
                <text>Journal of Pure and Applied Microbiology</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="36628">
                <text>Microbiology</text>
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              <name>Title</name>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Global Status of COVID-19 Diagnosis: An Overview</text>
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                <text>Kuldeep Dhama, Bhoj Raj Singh, Shiv Varan Singh, Karthikeyan Ravichandran, Subbaiyan Anbazhagan, Himani Agri, Ramkumar N. Rupner, Vinodh Kumar Obli Rajendran</text>
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                <text>Since the beginning of the New Year 2020, countries around the world are stumbling due to thecoronavirus disease (COVID-19) pandemic. Better approaches of diagnostics and medical facilitieshave helped some countries recover early. Previous exposures to epidemics have imparted lessons tohandle such a pandemic with a high level of preparedness. The World Health Organization (WHO) andnational health authorities are taking great efforts via efficient and impactful interventions to containthe virus. Diagnostic tests such as reverse transcription-polymerase chain reaction are increasinglybeing used to confirm the diagnosis because testing biological samples for the presence of the virusis the definitive method to identify the disease, analyze the risk for transmission, and determinewhether someone has been cured or not. It is also important to screen asymptomatic individualsto get the exact overview of the virus spread. Antibody detection plays a pivotal role in diagnosis;however, using it at the wrong time yields negative results and conveys dissenting opinion about thetests. Although the scaling up of testing has been significant, overall testing has been limited by theavailability of diagnostics. Rapid diagnoses and discontinuation of transmission are keys to endingthis pandemic. Diagnostics manufacturers are developing test kits and distributing them to differentcountries. Therefore, more than 500 commercial test kits for molecular- and immunoassays, most withEmergency Use Authorization, are now becoming available in the market. In this review, we discussthe importance of diagnostics, approaches of different countries toward the epidemic, global testingsituation, and lessons to countries at the start of the epidemic for better preparedness.</text>
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                <text>2020</text>
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                <text>diagnosis, RT-PCR, specificity, Sensitivity, SARS-CoV-2, COVID-19</text>
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            <name>Identifier</name>
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                <text>DOI: 10.22207/JPAM.14.SPL1.25</text>
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            <name>Source</name>
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              <elementText elementTextId="36617">
                <text>Journal of Pure and Applied Microbiology</text>
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                <text>Journal of Pure and Applied Microbiology</text>
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                <text>Microbiology</text>
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                <text>Jun Liu, Fang Zhang, Zhi Yang, Yingqi Hua, Wenhong Cheng</text>
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                <text>Background Facing the social panic and substantial shortage of medical resources during the coronavirus disease 2019 (COVID-19) outbreak, providing psychological first-aid to inpatients is essential for their rehabilitation and the orderly operating of medical systems. However, the closed-ward environment and extreme shortage of onsite mental health workers have limited the use of traditional face-to-face diagnosis and psychological interventions.Aim To develop a mental health intervention model for inpatients that can be applied during a widespread epidemic, such as COVID-19.Methods In a medical team stationed in Leishenshan Hospital, Wuhan, China, we integrated onsite and online psychological support resources to implement a graded psychological intervention system. The onsite psychiatrist established trust with the patients and classified them into categories according to their symptom severity. While face-to-face evaluation and intervention are critical for effective online support, the online team effectively extended the scope of the ‘first-aid’ to all patients.Conclusion This integrated onsite and online approach was effective and efficient in providing psychological interventions for inpatients during the crisis. Our model provides a realistic scheme for healthcare systems in or after the COVID-19 epidemic and also could be adopted in areas of the world with insufficient mental healthcare resources.</text>
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                <text>2020</text>
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                <text>DOI: 10.1136/gpsych-2020-100292</text>
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          <element elementId="48">
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              <elementText elementTextId="36608">
                <text>General Psychiatry</text>
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                <text>BMJ Publishing Group</text>
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                <text>Psychiatry</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>What the COVID-19 pandemic should teach us</text>
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                <text>Robbins RA</text>
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                <text>No abstract available. Article truncated after 150 words. As I write this between telemedicine patients on June 16th, I am reflecting back on the pandemic and what we have learned so far, not in how to diagnose or care for the COVID-19 patients, but in government and healthcare administration’s response to the pandemic. Politicians have made both good and poor decisions regarding the COVID-19 pandemic. In the summer of 2005, President George W. Bush was on vacation at his ranch in Crawford, Texas, when he began flipping through an advance reading copy of a new book about the 1918 influenza pandemic (1). He couldn't put it down. What was born was the nation's most comprehensive pandemic plan -- a playbook that included diagrams for a global early warning system, funding to develop new, rapid vaccine technology, and a robust national stockpile of critical supplies, such as face masks and ventilators. Bush’s remarks from 15 years ago still resonate. …</text>
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                <text>2020</text>
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                <text>leadership, preparedness, World Health Organization, hydroxychloroquine, Pandemic, Governor, Misinformation, President, COVID-19, hyperfinancialization</text>
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              <elementText elementTextId="36599">
                <text>DOI: 10.13175/swjpcc042-20</text>
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                <text>Southwest Journal of Pulmonary and Critical Care</text>
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                <text>Arizona Thoracic Society</text>
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                <text>General Works, Medical emergencies. Critical care. Intensive care. First aid</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Current Status of Treatment Options, Clinical Trials, and Vaccine Development for SARS-CoV-2 Infection</text>
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              <elementText elementTextId="36586">
                <text>Yuhong Yang, Ran Jing, Ramarao Vunnam, Adam Karevoll, Srinivas Rao Vunnam</text>
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                <text>The severe acute respiratory syndrome virus (SARS-CoV-2), a novel coronavirus first discovered inWuhan, China in December 2019 causes the Coronavirus Disease 19 (COVID-19), which presents with a wide range of clinical symptoms from mild or moderate to severe and critical illnesses. With thecontinuing transmission of the virus worldwide and the rapidly evolving situation globally, the WorldHealth Organization (WHO) declared the COVID-19 outbreak a pandemic in March. Currently, thereis no proven specific treatment for this potentially deadly disease beyond supportive care. However,a massive effort has been put globally into the investigation of medications and other interventionalmeasures to fight COVID-19. Convalescent plasma therapy from recovered patients has recently drawnconsiderable interest. Several alternative medical treatments, although evidence of their efficacy stilllacking, have also gained popularity, especially in countries with such traditions such as India and China.Rapid repurposing of drugs for COVID-19 has revealed a few promising candidate antiviral agents, butfurther research, especially high quality randomized controlled trials, will be needed to prove theirefficacy and safety in the clinical use to treat COVID-19. Vaccine development has been the imperativetask in the battle against SARS-CoV-2. While clinical trials have been launched for several candidatevaccines, research on COVID-19 vaccines is still at an early stage. So far, optimized supportive careremains the best practice against COVID-19.</text>
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                <text>vaccine, Supportive care, Clinical trials, SARS-CoV-2, COVID-19</text>
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                <text>DOI: 10.22207/JPAM.14.SPL1.10</text>
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              <elementText elementTextId="36591">
                <text>Journal of Pure and Applied Microbiology</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="36592">
                <text>Journal of Pure and Applied Microbiology</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="36593">
                <text>Microbiology</text>
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  <item itemId="3996" public="1" featured="0">
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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          <element elementId="50">
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                <text>Does the Coronavirus (COVID-19) Pandemic Call for a New Model of Older People Care?</text>
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            <name>Creator</name>
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              <elementText elementTextId="36578">
                <text>Giuseppe Liotta, Maria Cristina Marazzi, Leonardo Palombi, Stefano Orlando, Leonardo Emberti Gialloreti</text>
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                <text>2020</text>
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                <text>Italy, older people, Frailty, COVID-19, corona virus disease 2019, novel coronavirus SARS-CoV-2</text>
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                <text>DOI: 10.3389/fpubh.2020.00311</text>
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              <elementText elementTextId="36582">
                <text>Frontiers in Public Health</text>
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                <text>Frontiers Media S.A.</text>
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                <text>Public aspects of medicine</text>
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              <name>Title</name>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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        <name>Dublin Core</name>
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          <element elementId="50">
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                <text>Stress and sleep: a survey based on wearable sleep trackers among medical and nursing staff in Wuhan during the COVID-19 pandemic</text>
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              <elementText elementTextId="36570">
                <text>Chen Zhang, Zhen Wang, Xiaohui Wang, Kaiming Zhuo, Cunyou Gao</text>
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                <text>Backgroud COVID-19 pandemic has significantly affected the sleep health of local medical and nursing staff.Aim We used wearable pulse oximeters to monitor and screen the medical and nursing staff working in hospitals designated for COVID-19 in the Wuhan area. This study aimed to establish a reliable basis to provide sleep intervention for the medical and nursing staff.Methods Thirty medical and nursing staff members with symptoms of insomnia were instructed to wear medical ring-shaped pulse oximeters to monitor their sleep overnight. We also used the Insomnia Severity Index (ISI) and the Chinese version of the Self-Reporting Questionnaire (SRQ-20) to evaluate the severity of insomnia and mental health status, respectively, for each participant.Results Among the 30 participants, only 26 completed the screening. Ten cases (38.5%) demonstrated moderate to severe sleep apnoea–hypopnea syndrome (SAHS) when using an oxygen desaturation index ≥15 times/hour as the cut-off value. Participants with comorbid moderate to severe SAHS had significantly higher ISI and SRQ scores (p values 0.034 and 0.016, respectively) than those in the insomnia group. Correlation analysis revealed that ISI was positively correlated with total sleep time (TST) (r=0.435, p=0.026), and negatively correlated with deep sleep (r=−0.495, p=0.010); furthermore, patient SRQ scores were positively correlated with TST, sleep efficiency (SE) and REM (rapid eyes movement) sleep % (r=0.454 and 0.389, 0.512; p=0.020, 0.050 and 0.008, respectively). Stepwise logistic regression indicated that SRQ-20 and sex were risk factors for insomnia with comorbid SAHS, and their OR values were 1.516 and 11.56 (95% CI 1.053 to 2.180 and 1.037 to 128.9), respectively.Conclusion Medical and nursing staff with insomnia showed clear signs of comorbid sleep apnoea attributable to stress. The wearable pulse oximeters accurately monitored the participants’ breathing when asleep.</text>
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                <text>DOI: 10.1136/gpsych-2020-100260</text>
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                <text>General Psychiatry</text>
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                <text>BMJ Publishing Group</text>
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                <text>Psychiatry</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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          <element elementId="50">
            <name>Title</name>
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                <text>COVID-19 and cardiovascular disease in elderly patients: a challenge in the challenge</text>
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            <name>Creator</name>
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                <text>Raffaele Costa, Giovanni Ruotolo, Alberto Castagna, Carmen Ruberto, Carlo Torchia</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>On 11 March 2020, the World Health Organization declared a pandemic state, in relation to the spread of the severe acute respiratory syndrome-coronavirus disease-2, responsible for the coronavirus disease-2019 (COVID-19). The pandemical blast of COVID-19 uncovered well known weakness of financial chain and put our economic organizations facing off dramatic consequences if new strategies will not be developed to adapt health-care on detailed sub-groups of patients. Frail individual aged &gt;65 years affected by cardiovascular disease are an aged population that showed a particular attitude to contract infection and a higher mortality rate compared to general population. In this brief article, we will focus on the management of issues related to cardiovascular patients facing coronavirus infection, in particular in the most fragile groups of the population such as the elderly, increasingly numerous and affected by multimorbidity. Protecting aged populations will be a central question, probably primary in everyone's interest.</text>
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            <name>Date</name>
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                <text>2020</text>
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          <element elementId="49">
            <name>Subject</name>
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                <text>elderly, Cardiovascular patients, COVID-19</text>
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            <name>Identifier</name>
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                <text>DOI: 10.4081/gc.2020.9121</text>
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            <name>Source</name>
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                <text>Geriatric Care</text>
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            <name>Publisher</name>
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                <text>PAGEPress Publications</text>
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            <name>Coverage</name>
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                <text>Geriatrics</text>
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