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                  <text>Dominio científico: Coronavirus</text>
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                <text>Amid COVID-19: the importance of developing an positive adverse drug reaction (ADR) and medical device incident (MDI) reporting culture for Global Health and public safety</text>
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                <text>Stephanie Lee, Ali Elbeddini, Aniko Yeats</text>
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                <text>Abstract Amid COVID-19 Crisis, reporting adverse drug reactions (ADRs) and medical device incidents (MDIs) to Health Canada or health authorities in every country is crucial for monitoring medication safety and improving public health. Health Canada, for example, through their online database, has facilitated the process of reporting side effects relating to drugs and medical devices. However, several patients and health care professionals still fail to voluntarily report adverse events. For health care providers, some barriers to reporting may include fear of negative feedback, apathy, legal concerns, and uncertainty about whether an incident qualifies as an ADR. In the current COVID-19 Crisis, it is especially important for health care providers to be diligent about reporting Adverse Drug Reactions (ADRs), since misinformation propagated by the media is causing patients to misuse certain medications. We need to shift the current thought process about ADR reporting in order to encourage a positive reporting culture by patients and health care providers.</text>
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                <text>2020</text>
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                <text>reporting, patient safety, Adverse drug reaction, COVID-19, Medical device incident</text>
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            <name>Identifier</name>
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                <text>DOI: 10.1186/s40545-020-00219-1</text>
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                <text>Journal of Pharmaceutical Policy and Practice</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>BMC</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Therapeutics. Pharmacology, Pharmacy and materia medica</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Being a cornea specialist in Coronavirus pandemic</text>
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                <text>Pinar Kosekahya</text>
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                <text>Since March 11, there is a coronavirus pandemic. The disease has been named as Coronavirus Disease 2019 (COVID-19). Pandemic affected most heavily healthcare workers, especially physicians. Ophthalmologists have taken some tasks such as cancelling non-essential outpatient visits and elective surgeries. Proper personal protective equipment use is extremely important in ophthalmologic examinations as these examinations necessitate close touch with the patient. Coronavirus can spread via conjunctiva. Discontinuation of contact lens use may be helpful in this period. Patients using contact lenses should carefully obey hygiene rules.</text>
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                <text>2020</text>
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                <text>infection, Córnea, coronavirus, SARS-CoV-2, COVID-19</text>
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            <name>Identifier</name>
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                <text>DOI: </text>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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                <text>Clinical and Experimental Ocular Trauma and Infection</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="31366">
                <text>Clinical and Experimental Ocular Trauma and Infection</text>
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                <text>Ophthalmology</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>COVID-19 Pandemic and Ophthalmic Effect on Strabismus and Pediatric Eye Disorders</text>
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            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="31351">
                <text>Ayse Gul Kocak Altintas</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>An ongoing outbreak of pandemic caused by a novel coronavirus has severely infected humans worldwide. Even the characteristic symptom of COVID-19 is severe respiratory distress it also neurological involvement. In addition to its direct effect on human health, during the pandemic, several regular screening programs and periodic long term treatments were interrupted. Ophthalmic screening programs of children are essential for early diagnosis and correct treatment for the prevention of irreversible visual loss. In this article, potential symptoms of COVID-19 and ocular side effects on the pediatric population are discussed.</text>
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              <elementText elementTextId="31353">
                <text>2020</text>
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                <text>strabismus, Neurological involvement, Pandemic, COVID-19, pediatric eye</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="31355">
                <text>DOI: </text>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="31356">
                <text>Clinical and Experimental Ocular Trauma and Infection</text>
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            <name>Publisher</name>
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              <elementText elementTextId="31357">
                <text>Clinical and Experimental Ocular Trauma and Infection</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Ophthalmology</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Understanding Surgical Risk During COVID-19 Pandemic: The Rationale Behind the Decisions</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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                <text>Alexandros Triantafyllidis, Konstantinos Blouhos, Anestis Hatzigeorgiadis, Aikaterini Paraskeva, Konstantinos Andreas Boulas, Maria Nathanailidou, Konstantinos Hatzipourganis</text>
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            <name>Date</name>
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                <text>2020</text>
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            <name>Subject</name>
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                <text>safety, emergency surgery, pandemia, surgeon, SARS-CoV-2, COVID-19</text>
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            <name>Identifier</name>
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              <elementText elementTextId="31346">
                <text>DOI: 10.3389/fsurg.2020.00033</text>
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              <elementText elementTextId="31347">
                <text>Frontiers in Surgery</text>
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              <elementText elementTextId="31348">
                <text>Frontiers Media S.A.</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Surgery</text>
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  <item itemId="3379" public="1" featured="0">
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            <element elementId="50">
              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                <elementText elementTextId="2">
                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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          <element elementId="50">
            <name>Title</name>
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              <elementText elementTextId="31333">
                <text>A Primary Mediastinal Large B-Cell Lymphoma Patient With COVID-19 Infection After Intensive Immunochemotherapy: A Case Report</text>
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            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="31334">
                <text>Tao Liu, Li-Ling Zhang, Gang Wu, Yin Xiao, Fang Zhu, Xin-Xiu Liu, Qiuhui Li</text>
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                <text>Background: The outbreak of coronavirus disease 2019 (COVID-19) had become a global public health event. Lymphoma patients need to be distinguished from the general population because of their deficient immune status and intensive anti-tumor treatment. The impacts of cancer subtypes and treatment on COVID-19 infection are unclear.Case Presentation: We here report the case of a primary mediastinal large B-cell lymphoma patient who was infected with COVID-19 after intensive immunochemotherapy (DA-EPOCH-R). The patient developed a neutropenic fever during chemotherapy, and fever was persistent, although antibiotics were used. Initial chest CT was negative, and the patient received a throat swab test since the second CT showed evidence of pneumonia. With treatment with Arbidol Hydrochloride and LianHuaQingWen capsule, his COVID-19 was cured.Conclusions: To the best of our knowledge, this is the first report focusing on COVID-19 infection in a lymphoma patient undergoing intensive immunochemotherapy. For those patients being treated with immunochemotherapy in epidemic areas, a reduced dose intensity of intensive chemotherapy should be considered, and the effect of immunotherapies such as rituximab on COVID-19 infection should be considered. The impacts of anti-cancer treatment on COVID-19 infection need to be explored further.</text>
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                <text>2020</text>
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                <text>immunotherapy, lymphoma, chemotherapy, myelosuppression, COVID-19</text>
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                <text>DOI: 10.3389/fonc.2020.00924</text>
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                <text>Frontiers in Oncology</text>
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            <description>An entity responsible for making the resource available</description>
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                <text>Frontiers Media S.A.</text>
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                <text>Neoplasms. Tumors. Oncology. Including cancer and carcinogens</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Yi Zhou, Yanan Liu, Xinyi Li, Xinghuan Wang, Fuling Zhou, Minghui LIU, Liang Shao, Haojian Zhang, Ruixian Zhang, Yalan Yu</text>
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                <text>Background. The outbreak of COVID-19 has attracted the attention of the whole world. Our study aimed to describe illness progression and risk profiles for mortality in non-survivors.Methods. We retrospectively analyzed 155 patients with COVID-19 in Wuhan and focused on 18 non-survivors among them. Briefly, we compared the dynamic profile of biochemical and immune parameters and drew an epidemiological and clinical picture of disease progression from disease onset to death in non-survivors. The survival status of the cohort was indicated by a Kaplan–Meier curve.Results. Of the non-survivors, the median age was 73.5 years, and the proportion of males was 72.2%. Five and 13 patients were hospital-acquired and community-acquired infection of SARS-CoV-2, respectively. The interval between disease onset and diagnosis was 8.5 days (IQR, [4–11]). With the deterioration of disease, most patients experienced consecutive changes in biochemical parameters, including lymphopenia, leukocytosis, thrombocytopenia, hypoproteinemia, as well as elevated D-dimer and procalcitonin. Regarding the immune dysregulation, patients exhibited significantly decreased T lymphocytes in the peripheral blood, including CD3+T, CD3+CD4+Th, and CD3+CD8+Tc cells. By the end of the disease, most patients suffered from severe complications, including ARDS (17/18; 94.4%), acute cardiac injury (10/18; 55.6%), acute kidney injury (7/18; 38.9%), shock (6/18; 33.3%), gastrointestinal bleeding (1/18; 5.6%), as well as perforation of intestine (1/18; 5.6%). All patients died within 45 days after the initial hospital admission with a median survivor time of 13.5 days (IQR, 8–17).Conclusions. Our data show that patients experienced consecutive changes in biochemical and immune parameters with the deterioration of the disease, indicating the necessity of early intervention.</text>
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                <text>2020</text>
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            <name>Subject</name>
            <description>The topic of the resource</description>
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                <text>disease progression, SARS-CoV-2, COVID-19, non-survivor, complete clinical course</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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                <text>DOI: 10.3389/fmed.2020.00246</text>
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            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="31330">
                <text>Frontiers in Medicine</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="31331">
                <text>Frontiers Media S.A.</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Medicine (General)</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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            <description>A name given to the resource</description>
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                <text>Finding the Calm in the Chaos: An Institutional Protocol for Anesthetic Management of a Patient for Neurosurgery during Coronavirus  Disease 2019 Pandemic</text>
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            <description>An entity primarily responsible for making the resource</description>
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                <text>Thomas Koshy, Manikandan Sethuraman, Unnikrishnan Prathapadas, Neeraja Ajayan, Aishvarya Shree Nedunchezhian, Ajay Prasad Hrishi P.</text>
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            <description>An account of the resource</description>
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                <text>“Coronavirus disease 2019” (COVID-19) transmitted by a novel coronavirus via contact or droplet spread is a highly infectious disease, the containment of which requires vigilance and stringent infection control policies. In the backdrop of hospitals becoming hot zones and an increasing number of health care workers contracting the disease, it is crucial to formulate an approach while administering anesthesia during the testing times of COVID-19 pandemic. In this background, this comprehensive article deals with the perioperative management during this pandemic and includes risk stratification based on an innovative simple scoring system, rationale use of personal protective equipments, and infection prevention protocols. The document of updated literature, though not intended to replace any guidelines, is aimed at providing protocol to health care workers to protect themselves while providing the best care in this pandemic.</text>
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            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2020</text>
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            <name>Subject</name>
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                <text>risk stratification, personal protective equipment, Neuroanesthesia, COVID-19</text>
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            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="31320">
                <text>DOI: 10.1055/s-0040-1712773</text>
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            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="31321">
                <text>Journal of Neurosciences in Rural Practice</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="31322">
                <text>Thieme Publishers</text>
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            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="31323">
                <text>Neurosciences. Biological psychiatry. Neuropsychiatry</text>
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              <name>Title</name>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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            <name>Title</name>
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                <text>COVID-19</text>
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            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="31309">
                <text>Mará Carolina Cabrera Schulmeyer</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2020</text>
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            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="31311">
                <text>DOI: 10.25237/revchilanestv49n03.01</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="31312">
                <text>Revista Chilena de Anestesia</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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              <elementText elementTextId="31313">
                <text>Editorial Iku</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="31314">
                <text>Medicine, Anesthesiology</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>COVID-19: No olvidemos los fundamentos</text>
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              <elementText elementTextId="31302">
                <text>Guillermo Bugedo, Eduardo Kattan</text>
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            <name>Date</name>
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                <text>DOI: 10.25237/revchilanestv49n03.02</text>
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                <text>Revista Chilena de Anestesia</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>Editorial Iku</text>
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                <text>Medicine, Anesthesiology</text>
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                <text>COVID-19 y afectación cardíaca</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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                <text>Miguel Ángel García Fernández, Jose Juan Gomez de Diego</text>
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                <text>DOI: 10.25237/revchilanestv49n03.018</text>
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                <text>Revista Chilena de Anestesia</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
            <elementTextContainer>
              <elementText elementTextId="31300">
                <text>Medicine, Anesthesiology</text>
              </elementText>
            </elementTextContainer>
          </element>
        </elementContainer>
      </elementSet>
    </elementSetContainer>
  </item>
</itemContainer>
