199 10 20655 https://www.socictopen.socict.org/files/original/44589239fead0a77ff3d0249ea7602d4.pdf 9c450e8bbb23b21d2939c16ca9230027 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Nipah outbreak in North Kerala – What worked? Insights for future response and recovery based on examination of various existing frameworks Creator An entity primarily responsible for making the resource Asma Ayesha Rahim, Thomas V Chacko Description An account of the resource Asia Pacific region has been witnessing numerous public health emergencies in recent years with the Nipah outbreak in North Kerala (2018), India, needs special mention. Threats posed and experiences gained have compelled health systems to draft frameworks nationally and internationally for preparedness, outbreak response, and recovery. Our failure to obtain comprehensive guiding frameworks for application in the Indian context for Ebola, Severe Acute Respiratory Syndrome, Influenza A (H1N1), and Nipah outbreaks led us to the search outside India for frameworks that have worked in the past. A thorough review of the WHO, Centers for Disease Control and Prevention, and Malaysian framework was done to identify explicit components and replicable objectives to the national context. In the absence of a specific framework, Nipah recovery and response experience that worked in Kerala outbreak (2018) was compared against novel H1N1 (2015) guidelines at national level. This article provides the groundwork and insights as a value addition toward an India-specific framework of action for response and recovery for Nipah outbreaks in future. Date A point or period of time associated with an event in the lifecycle of the resource 2019 Subject The topic of the resource frameworks, India, infectious diseases, Nipah outbreak, outbreak response and recovery Identifier An unambiguous reference to the resource within a given context DOI: 10.4103/ijph.IJPH_117_19 Source A related resource from which the described resource is derived Indian Journal of Public Health Publisher An entity responsible for making the resource available Wolters Kluwer Medknow Publications Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Public aspects of medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/70dfa04acc6456a96c568411ecc7af49.pdf a356b63d272f7bc105d9f81c8de88df6 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource BROCKMAN: deciphering variance in epigenomic regulators by k-mer factorization Creator An entity primarily responsible for making the resource Carl G. de Boer, Aviv Regev Description An account of the resource Abstract Background Variation in chromatin organization across single cells can help shed important light on the mechanisms controlling gene expression, but scale, noise, and sparsity pose significant challenges for interpretation of single cell chromatin data. Here, we develop BROCKMAN (Brockman Representation Of Chromatin by K-mers in Mark-Associated Nucleotides), an approach to infer variation in transcription factor (TF) activity across samples through unsupervised analysis of the variation in DNA sequences associated with an epigenomic mark. Results BROCKMAN represents each sample as a vector of epigenomic-mark-associated DNA word frequencies, and decomposes the resulting matrix to find hidden structure in the data, followed by unsupervised grouping of samples and identification of the TFs that distinguish groups. Applied to single cell ATAC-seq, BROCKMAN readily distinguished cell types, treatments, batch effects, experimental artifacts, and cycling cells. We show that each variable component in the k-mer landscape reflects a set of co-varying TFs, which are often known to physically interact. For example, in K562 cells, AP-1 TFs were central determinant of variability in chromatin accessibility through their variable expression levels and diverse interactions with other TFs. We provide a theoretical basis for why cooperative TF binding – and any associated epigenomic mark – is inherently more variable than non-cooperative binding. Conclusions BROCKMAN and related approaches will help gain a mechanistic understanding of the trans determinants of chromatin variability between cells, treatments, and individuals. Date A point or period of time associated with an event in the lifecycle of the resource 2018 Subject The topic of the resource single cell, epigenome, chromatin, scATAC-seq, k-mer, N-gram Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s12859-018-2255-6 Source A related resource from which the described resource is derived BMC Bioinformatics Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General), Computer applications to medicine. Medical informatics Language A language of the resource EN https://www.socictopen.socict.org/files/original/ebf43a16b48f833e46070fb0adcde9b3.pdf 9d580d945ce7533bd948540e8e7e2d53 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Clinical and Epidemiological Features of New Polyethiologic Viral Infections Creator An entity primarily responsible for making the resource V. V. Shkarin, O. V. Kovalyshen, R. F. Chanysheva, A. V. Sergeeva, A. A. Rassokhin Description An account of the resource The review article summarizes and systematizes scientific data on the pathogens of new respiratory infections discovered in the early XXI century – Human metapneumovirus (HMPV), Human bocavirus (HBoV), Human coronavirus (HCoV). Groups of microorganisms with which they act as associates are identified: other viruses (HMPV – HRSV, Rhinovirus, Adenovirus, HCoV; НBoV– Rhinovirus, HRSV, Rotavirus, Norovirus; HCoV – Influenza virus, Adenovirus and HRSV), and also some bacteria (HMPV – S. pneumoniae, H. influenzae type b; НBoV – S. enteritidis, C. jejune; HCoV – M. pneumoniae, K. pneumoniae). The clinical and epidemiological features of combined forms of infections are analyzed: predominance of moderate course, with risk of complications, risk groups (young children), seasonality (autumn-winter). The complexity of verification of these infections from other viral infections based on the clinical picture is established. Date A point or period of time associated with an event in the lifecycle of the resource 2018 Subject The topic of the resource Respiratory Infections, combined infections Identifier An unambiguous reference to the resource within a given context DOI: 10.31631/2073-3046-2018-17-4-4-12 Source A related resource from which the described resource is derived Эпидемиология и вакцинопрофилактика Publisher An entity responsible for making the resource available Numikom LLC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Epistemology. Theory of knowledge Language A language of the resource RU https://www.socictopen.socict.org/files/original/e33a4d6d0c90828deebe57a4cc9c59c7.pdf 29397bb513d99def123558b0c08a6a29 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The Canadian Geospatial Data Infrastructure and health mapping Creator An entity primarily responsible for making the resource Sheng Gao, Darka Mioc, Xiaolun Yi, François Anton, Eddie Oldfield, David J. Coleman Description An account of the resource Due to the recent outbreak of SARS and the danger of pandemic Bird Flu, the ability to strengthen health surveillance and disease control is a growing need among governments. The development of the Canadian Geospatial Data Infrastructure (CGDI) has shown great potential in many industries such as emergency management, public health, disaster relief, environmental impact assessment, transportation, and land information systems. In this paper, our aims are to use the CGDI and to identify its usability in supporting online health mapping. To identify the usability of the CGDI for health mapping, we employed nine usability metrics. We also designed an architecture based on the CGDI to support the basic functions for health mapping, and implemented an infectious disease simulation for New Brunswick and Maine. Within the CGDI framework, this research enabled cross-border health data visualization, integration, sharing, and exploring the spatio-temporal trends of an infectious disease outbreak through thematic maps. Based on the experience of the developers and the feedback from users, an evaluation of the usability matrix with the CGDI components (technical standards, national framework data, enabling technologies, and common data policies) was explored using this cross-border health mapping application. The use of the CGDI in health applications has a great potential in supporting effective and secure health data sharing and integration. Enrichment of the CGDI would further facilitate the data sharing and improve decision making efficiency and effectiveness. Date A point or period of time associated with an event in the lifecycle of the resource 2008 Subject The topic of the resource Health, mapping, usability, CGDI, data-sharing Identifier An unambiguous reference to the resource within a given context DOI: 10.4000/cybergeo.21123 Source A related resource from which the described resource is derived Cybergeo Publisher An entity responsible for making the resource available Unité Mixte de Recherche 8504 Géographie-cités Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Geography (General) Language A language of the resource DE, EN, FR, IT, PT https://www.socictopen.socict.org/files/original/105b26af72b933f11b1e276fb44c9bc7.pdf 803dfbcab682855d8f7bb81f1d8c0c92 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Arapan-S: a fast and highly accurate whole-genome assembly software for viruses and small genomes Creator An entity primarily responsible for making the resource Sahli Mohammed, Shibuya Tetsuo Description An account of the resource Abstract Background Genome assembly is considered to be a challenging problem in computational biology, and has been studied extensively by many researchers. It is extremely difficult to build a general assembler that is able to reconstruct the original sequence instead of many contigs. However, we believe that creating specific assemblers, for solving specific cases, will be much more fruitful than creating general assemblers. Findings In this paper, we present Arapan-S, a whole-genome assembly program dedicated to handling small genomes. It provides only one contig (along with the reverse complement of this contig) in many cases. Although genomes consist of a number of segments, the implemented algorithm can detect all the segments, as we demonstrate for Influenza Virus A. The Arapan-S program is based on the de Bruijn graph. We have implemented a very sophisticated and fast method to reconstruct the original sequence and neglect erroneous k-mers. The method explores the graph by using neither the shortest nor the longest path, but rather a specific and reliable path based on the coverage level or k-mers’ lengths. Arapan-S uses short reads, and it was tested on raw data downloaded from the NCBI Trace Archive. Conclusions Our findings show that the accuracy of the assembly was very high; the result was checked against the European Bioinformatics Institute (EBI) database using the NCBI BLAST Sequence Similarity Search. The identity and the genome coverage was more than 99%. We also compared the efficiency of Arapan-S with other well-known assemblers. In dealing with small genomes, the accuracy of Arapan-S is significantly higher than the accuracy of other assemblers. The assembly process is very fast and requires only a few seconds. Arapan-S is available for free to the public. The binary files for Arapan-S are available through http://sourceforge.net/projects/dnascissor/files/. Date A point or period of time associated with an event in the lifecycle of the resource 2012 Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/1756-0500-5-243 Source A related resource from which the described resource is derived BMC Research Notes Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General), Science (General), Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/84fc24fe77eca1109d831ebe4b0d0e37.pdf 549b389238b6f57a85bc2fee7917d545 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Introduction Pages Creator An entity primarily responsible for making the resource Radu E. Sestraş Description An account of the resource Notulae Scientia Biologicae (http://www.notulaebiologicae.ro), Issue 3, Volume 11, 2019: The papers published in this issue (https://www.notulaebiologicae.ro/index.php/nsb/issue/view/265) represent interesting novelties in different topics of life science. Among the exciting researches, we invite readers to find news about: pharmacological uses and health benefits of ginger (Zingiber officinale) in traditional Asian and ancient Chinese medicine, and modern practice; middle east respiratory syndrome: its occurrence, aetiology, epidemiology, associated clinicopathological findings, diagnosis, prevention and control in humans and animals; ethanolic extract of Chrysophyllum albidum stem bark prevents alloxan-induced diabetes; prevalence of group a rotavirus, some risk factors and clinical signs of the infection in children under five years in Yobe State, Nigeria; prevalence of increased serum urea and creatinine levels in dogs; impact of heat stress on blood and serum biochemistry parameters in rats; acute and sub-acute toxicity of Ganoderma applanatum (Pres.) Pat. extract mediated silver nanoparticles on rat; in-vitro control of oral thrush causal organisms using medicinal plants extracts; generic salmonella in asymptomatic adult volunteers: occurrence, antibiogram, extended-spectrum β-lactamase production and carbapenem resistance; impact of hydrogen peroxide on the secondary metabolites, enzyme activities and photosynthetic pigment accumulation of Vigna unguiculata L. (Walp); diversity, distribution and conservation status of the genus Tectaria Cav. from Deccan Peninsula and western Ghats of India. Date A point or period of time associated with an event in the lifecycle of the resource 2019 Subject The topic of the resource Notulae Scientia Biologicae, Issue 3, Volume 11, 2019 Identifier An unambiguous reference to the resource within a given context DOI: 10.15835/nsb11310567 Source A related resource from which the described resource is derived Notulae Scientia Biologicae Publisher An entity responsible for making the resource available University of Agricultural Sciences and Veterinary Medicine, Cluj-Napoca Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Agriculture (General), Science (General) Language A language of the resource EN https://www.socictopen.socict.org/files/original/2a6c68d5b2e84dcede2afa0ce65e30c4.pdf b31e2e5a99c4007395f46fdd714ca8e9 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The use of complementary and alternative medicine by patients with cancer: a cross-sectional survey in Saudi Arabia Creator An entity primarily responsible for making the resource Khadega A. Abuelgasim, Yousef Alsharhan, Tariq Alenzi, Abdulaziz Alhazzani, Yosra Z. Ali, Abdul-Rahman Jazieh Description An account of the resource Abstract Background A significant proportion of cancer patients use complementary and alternative medicine (CAM) along with conventional therapies (CT), whereas a smaller proportion delay or defer CT in favor of CAM. Previous studies exploring CAM use among cancer patients in the Middle East region have shown discrepant results. This study investigates the prevalence and pattern of CAM use by Saudi cancer patients. It also discusses the possible benefits and harm related to CAM use by cancer patients, and it explores the beliefs patients hold and their transparency with health care providers regarding their CAM use. Methods A cross-sectional study was conducted in oncology wards and outpatient clinics by using face-to-face interviews with the participants. Results A total of 156 patients with a median age of 50 years (18–84) participated in the study. The prevalence of CAM use was 69.9%; the most prominent types of CAM were those of a religious nature, such as supplication (95.4%), Quran recitation (88.1%), consuming Zamzam water (84.4%), and water upon which the Quran has been read (63.3%). Drinking camel milk was reported by 24.1% of CAM users, whereas camel urine was consumed by 15.7%. A variety of reasons were given for CAM use: 75% reported that they were using CAM to treat cancer, enhance mood (18.3%),control pain (11.9%), enhance the immune system (11%),increase physical fitness (6.4%), and improve appetite (4.6%). Thirty percent of CAM users had discussed the issue with their doctors; only 7.7% had done so with their nurses. Conclusions The use of CAM, including camel products, is highly prevalent among cancer patients in the Middle East, but these patients do not necessarily divulge their CAM use to their treating physicians and nurses. Although CAM use can be beneficial, some can be very harmful, especially for cancer patients. Association is known between camel products and brucellosis and Middle East respiratory syndrome coronavirus (MERS-CoV). Both can lead to tremendous morbidity in immune-compromised patients. Doctor–patient communication regarding CAM use is of paramount importance in cancer care. Date A point or period of time associated with an event in the lifecycle of the resource 2018 Subject The topic of the resource Complementary and Alternative Medicine, religious belief, cancer, Camel products, brucellosis, Middle East respiratory syndrome coronavirus (MERS-CoV) Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s12906-018-2150-8 Source A related resource from which the described resource is derived BMC Complementary and Alternative Medicine Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Other systems of medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/7464f1b0b824727e679d1327eff3937c.pdf 914d94002f8b6679e194eb6cefefea70 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Technoeconomic Modeling of Plant-Based Griffithsin Manufacturing Creator An entity primarily responsible for making the resource Aatif Alam, Linda Jiang, Gregory A. Kittleson, Kenneth D. Steadman, Somen Nandi, Joshua L Fuqua, Kenneth E. Palmer, Daniel Tusé, Karen A. McDonald Description An account of the resource Griffithsin is a marine algal lectin that exhibits broad-spectrum antiviral activity by binding oligomannose glycans on viral envelope glycoproteins, including those found in HIV-1, HSV-2, SARS, HCV and other enveloped viruses. An efficient, scalable and cost-effective manufacturing process for Griffithsin is essential for the adoption of this drug in human antiviral prophylaxis and therapy, particularly in cost-sensitive indications such as topical microbicides for HIV-1 prevention. The production of certain classes of recombinant biologics in plants can offer scalability, cost and environmental impact advantages over traditional biomanufacturing platforms. Previously, we showed the technical viability of producing recombinant Griffithsin in plants. In this study, we conducted a technoeconomic analysis (TEA) of plant-produced Griffithsin manufactured at commercial launch volumes for use in HIV microbicides. Data derived from multiple non-sequential manufacturing batches conducted at pilot scale and existing facility designs were used to build a technoeconomic model using SuperPro Designer® modeling software. With an assumed commercial launch volume of 20 kg Griffithsin/year for 6.7 million doses of Griffithsin microbicide at 3 mg/dose, a transient vector expression yield of 0.52 g Griffithsin/kg leaf biomass, recovery efficiency of 70%, and purity of >99%, we calculated a manufacturing cost for the drug substance of $0.32/dose and estimated a bulk product cost of $0.38/dose assuming a 20% net fee for a contract manufacturing organization (CMO). This is the first report modeling the manufacturing economics of Griffithsin. The process analyzed is readily scalable and subject to efficiency improvements and could provide the needed market volumes of the lectin within an acceptable range of costs, even for cost-constrained products such as microbicides. The manufacturing process was also assessed for environmental, health and safety impact and found to have a highly favorable environmental output index with negligible risks to health and safety. The results of this study help validate the plant-based manufacturing platform and should assist in selecting preferred indications for Griffithsin as a novel drug. Date A point or period of time associated with an event in the lifecycle of the resource 2018 Subject The topic of the resource biomanufacturing, economics, Griffithsin, microbicide, antiviral, cost Identifier An unambiguous reference to the resource within a given context DOI: 10.3389/fbioe.2018.00102 Source A related resource from which the described resource is derived Frontiers in Bioengineering and Biotechnology Publisher An entity responsible for making the resource available Frontiers Media S.A. Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biotechnology Language A language of the resource EN https://www.socictopen.socict.org/files/original/f3875e2aa0b316a8e896ca0e8fc0fb41.pdf f4589fb3253b3cf1d9f5e06b22164c73 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Tonsillar cytokine expression between patients with tonsillar hypertrophy and recurrent tonsillitis Creator An entity primarily responsible for making the resource Emilia Mikola, Varpu Elenius, Maria Saarinen, Oscar Palomares, Matti Waris, Riitta Turunen, Tuomo Puhakka, Lotta Ivaska, Beate Rückert, Alar Aab, Tero Vahlberg, Tytti Vuorinen, Tobias Allander, Carlos A Camargo, Mübeccel Akdis, Cezmi A. Akdis, Tuomas Jartti Description An account of the resource Abstract Background Tonsils provide an innovative in vivo model for investigating immune response to infections and allergens. However, data are scarce on the differences in tonsillar virus infections and immune responses between patients with tonsillar hypertrophy or recurrent tonsillitis. We investigated the differences in virus detection and T cell and interferon gene expression in patients undergoing tonsillectomy due to tonsillar hypertrophy or recurrent tonsillitis. Methods Tonsils of 89 surgical patients with tonsillar hypertrophy (n = 47) or recurrent tonsillitis (n = 42) were analysed. Patients were carefully characterized clinically. Standard questionnaire was used to asses preceding and allergy symptoms. Respiratory viruses were analysed in tonsils and nasopharynx by PCR. Quantitative real-time PCR was used to analyse intratonsillar gene expressions of IFN-α, IFN-β, IFN-γ, IL-10, IL-13, IL-17, IL-28, IL-29, IL-37, TGF-β, FOXP3, GATA3, RORC2 and Tbet. Results Median age of the subjects was 15 years (range 2–60). Patients with tonsillar hypertrophy were younger, smoked less often, had less pollen allergy and had more adenovirus, bocavirus-1, coronavirus and rhinovirus in nasopharynx (all P  Date A point or period of time associated with an event in the lifecycle of the resource 2018 Subject The topic of the resource allergy, Asthma, Child, cytokine, interferon, interleukin Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s13601-018-0205-z Source A related resource from which the described resource is derived Clinical and Translational Allergy Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Immunologic diseases. Allergy Language A language of the resource EN https://www.socictopen.socict.org/files/original/54289d6e7f0d6ba029b86e16b30d384e.pdf fc534ef3a8975a86ca740c0696ac095a Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A Study of Inflammatory Markers in Gestational Diabetes Mellitus Creator An entity primarily responsible for making the resource Cuma Mertoglu, Murat Günay, Mehmet Güngör, Mehmet Kulhan, Nur Gözde Kulhan Description An account of the resource Objective: Gestational diabetes mellitus is a common disorder of carbohydrate metabolism, with onset or first recognition during pregnancy, resulting in hyperglycemia of variable severity. Insulin resistance and chronic subclinical inflammation are the underlying mechanisms of the disease. Soluble interleukin-2 receptor, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio are the markers of inflammatory disease processes such as type 1 and 2 diabetes mellitus, hepatitis, and neoplasms. Study Design: In our study, we measured complete blood count, serum soluble interleukin-2 receptor, serum glucose in blood samples from 52 women with gestational diabetes mellitus and 50 pregnant women with normal glucose tolerance. Pregnant women which were tested for oral glucose tolerance test (75 gr load) between 24 and 28 weeks of pregnancy were selected for the study. Gestational diabetes mellitus was defined according to the criteria provided by the National Institute for Health and Care Excellence. Results: In terms of age, gestational diabetes mellitus patients (mean±SD; 31±6 years) were older than controls (mean±SD; 25±5.3 years). Mean platelet volume values were lower in gestational diabetes mellitus patients (mean±SD; 10.3±1.4 fL) as compared to normal glucose tolerance group (mean±SD; 10.8±1fL). No statistically significant differences in serum glucose concentration, white blood cell count, neutrophil count, lymphocyte count, hemoglobin concentration, platelet count, neutrophil-to-lymphocyte ratio value, platelet-to-lymphocyte ratio value, and serum soluble interleukin-2 receptor concentration were found. Conclusion: This study did not reveal an increase in the inflammatory markers, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and serum soluble interleukin-2 receptor, in gestational diabetes mellitus. The mean platelet volume values were observed to be lower in gestational diabetes mellitus patients. Date A point or period of time associated with an event in the lifecycle of the resource 2019 Subject The topic of the resource neutrophil/lymphocyte ratio, platelet-lymphocyte ratio, Soluble interleukin-2 receptor, Mean platelet volume, gestational diabetes mellitus Identifier An unambiguous reference to the resource within a given context DOI: 10.21613/GORM.2018.775 Source A related resource from which the described resource is derived Gorm Publisher An entity responsible for making the resource available Medical Network Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine, Gynecology and obstetrics Language A language of the resource EN