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                  <text>Dominio científico: Coronavirus</text>
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                <text>Economic Power Comparison between United States and China in the Context of Covid-19 Pandemic: Based on Statistical Methods</text>
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                <text>Yang Yutong</text>
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                <text>Generally speaking, economic crises are caused by insufficient demand, while the economic crisis that may be caused by the Covid-19 epidemic started with insufficient supply. In the case of insufficient demand, countries often use a series of monetary policies to release liquidity, such as interest rate cuts, RRR cuts. However, the interest rate cut this time may not work well. This is because the interest rate cut can increase the liquidity of the market.While controlling the epidemic, we should promptly resume work and production, and produce a variety of commodities that meet consumer demand. During this period of time, the main strategy is not monetary policy. Instead, appropriate fiscal policies should be used to reduce the burden on enterprises so that they can survive this difficult time without dying before they start their careers. Only companies that can survive the epidemic are good companies that have combat effectiveness and can continue to conquer the market after the epidemic is over.Therefore, in the face of the Covid-19 epidemic, the competition between China and the United States should not be a zero-sum game because the United States is the final consumer of a large number of products produced by China, and the United States is still the world’s leader. If the US economy declines, it will definitely affect global economic development. When necessary, we also need to support the production of high-end consumer products in the United States and allocate a portion of the production capacity for them. Only when the two sides have healthy competition can the industrial chain of both sides be upgraded together.</text>
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                <text>10.1051/e3sconf/202123301163</text>
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                <text>Epidemiology and Health</text>
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                <text>Environmental sciences</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Cardiovascular Impairment in COVID-19: Learning From Current Options for Cardiovascular Anti-Inflammatory Therapy</text>
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                <text>Yang Zhang, Shuyang Zhang, Lun Wang</text>
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                <text>In December 2019, Coronavirus Disease 2019 (COVID-19) caused by SARS-CoV-2, occurred in China and has currently led to a global pandemic. In addition to respiratory involvement, COVID-19 was also associated with significant multiple organ dysfunction syndrome (MODS). Cardiovascular impairment has been observed and is now drawing growing attention. Cardiovascular protective strategies are urgent and of great significance to the overall prognosis of COVID-19 patients. Direct viral infection, cytokine storm, and aggravation of existing cardiovascular diseases were recognized as possible mechanisms of cardiovascular impairment in COVID-19. Hyperactivated inflammation plays an important role in all three mechanisms and is considered to be fundamental in the development of cardiovascular impairment and MODS in COVID-19. Therefore, in addition to conventional cardiovascular treatment, anti-inflammatory therapy is a reasonable strategy for severe cases to further enhance cardiovascular protection and potentially mitigate MODS. We reviewed the inflammatory features and current promising treatments of COVID-19 as well as cardiovascular anti-inflammatory therapies that have been verified in previous clinical trials with positive outcomes. We believe that targeting the central pathway (IL-1β, TNF-α, IL-6), balancing the Th1 and Th2 response, and administering long-term anti-inflammatory therapy might be promising prospects to reduce cardiovascular impairment and even MODS during the acute and recovery phases of COVID-19. The cardiovascular anti-inflammatory therapies might be of great application value to the management of COVID-19 patients and we further propose an algorithm for the selection of anti-inflammatory therapy for COVID-19 patients with or at high risk of cardiovascular impairment. We recommend to take the experiences in cardiovascular anti-inflammatory therapy as references in the management of COVID-19 and conduct related clinical trials, while the clinical translation of novel treatments from preclinical studies or in vitro drug screening should proceed with caution due to unguaranteed efficacy and safety profiles.</text>
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                <text>inflammation, cardiovascular diseases, corona virus disease 2019, cardiovascular impairment, cardiovascular anti-inflammatory therapy</text>
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                <text>DOI: 10.3389/fcvm.2020.00078</text>
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                <text>Frontiers in Cardiovascular Medicine</text>
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                <text>Frontiers Media S.A.</text>
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                <text>Diseases of the circulatory (Cardiovascular) system</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Yang Zhang, Wei Zhang, Gang Wang, Wei-qin LI, Zhou Zhou, Jing-chun SONG, People’s Liberation Army Professional Committee of Critical Care Medicine, Chinese Society on Thrombosis and Haemostasis</text>
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                <text>Abstract Since December 2019, a novel type of coronavirus disease (COVID-19) in Wuhan led to an outbreak throughout China and the rest of the world. To date, there have been more than 1,260,000 COVID-19 patients, with a mortality rate of approximately 5.44%. Studies have shown that coagulation dysfunction is a major cause of death in patients with severe COVID-19. Therefore, the People’s Liberation Army Professional Committee of Critical Care Medicine and Chinese Society on Thrombosis and Hemostasis grouped experts from the frontline of the Wuhan epidemic to come together and develop an expert consensus on diagnosis and treatment of coagulation dysfunction associated with a severe COVID-19 infection. This consensus includes an overview of COVID-19-related coagulation dysfunction, tests for coagulation, anticoagulation therapy, replacement therapy, supportive therapy and prevention. The consensus produced 18 recommendations which are being used to guide clinical work.</text>
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                <text>2020</text>
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                <text>diagnosis, treatment, Severe, Coagulation dysfunction, COVID-19</text>
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                <text>DOI: 10.1186/s40779-020-00247-7</text>
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                <text>Military Medical Research</text>
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                <text>BMC</text>
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                <text>Medicine (General), Military Science</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Convalescent Plasma Coupled With Medications for the Treatment of a Severe COVID-19 Patient: Drugs Analysis and Pharmaceutical Care Based on the Newly Established Guidelines for COVID-19 Remedy</text>
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                <text>Yang Zhang, Ying Wang, Qian Yu, Kun Zhu</text>
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                <text>Given the extreme importance of the current pandemic caused by COVID-19 and due to the fact that scientists agree that there is no identified treatment, this paper analyzes in detail the treatment of a severe COVID-19 patient with convalescent plasma and drugs based on current guidelines for COVID-19 diagnosis and treatment. This can provide a reference for other medical institutions on rational drug use and pharmaceutical care for severe COVID-19 patients.</text>
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                <text>guideline, therapeutic strategy, convalescent plasma, drugs analysis, COVID-19 (severe)</text>
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                <text>DOI: 10.3389/fphar.2020.00966</text>
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                <text>Frontiers in Pharmacology</text>
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                <text>Therapeutics. Pharmacology</text>
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                <text>Coronaviruses, including SARS-CoV, SARS-CoV-2, and MERS-CoV, have caused contagious and fatal respiratory diseases in humans worldwide. Notably, the coronavirus disease 19 (COVID-19) caused by SARS-CoV-2 spread rapidly in early 2020 and became a global pandemic. The nonstructural proteins of coronaviruses are critical components of the viral replication machinery. They function in viral RNA transcription and replication, as well as counteracting the host innate immunity. Studies of these proteins not only revealed their essential role during viral infection but also help the design of novel drugs targeting the viral replication and immune evasion machinery. In this review, we summarize the functional studies of each nonstructural proteins and compare the similarities and differences between nonstructural proteins from different coronaviruses.</text>
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                <text>Korean Society of Epidemiology</text>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Risk perception of coronavirus disease 2019 (COVID-19) and its related factors among college students in China during quarantine.</text>
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                <text>Yani Ding, Xueying Du, Qinmei Li, Miao Zhang, Qingjun Zhang, Xiaodong Tan, Qing Liu</text>
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                <text>ObjectiveAt the end of 2019, the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan was a serious threat to public health. This study aimed to evaluate the risk perception of COVID-19 among college students in China during the quarantine, explore its related factors, and provide reference for future study.MethodsThis study invited college students from various provinces of China to participate in the survey through the Internet, and a total of 1,461 college students were included. T-test and analysis of variance were used to explore the relationship between demographic characteristics, social pressure, knowledge and risk perception. Multiple linear regression was used to identify factors associated with risk perception.ResultsThis study shows that college students in China have high risk perception of COVID-19. Female college students (p</text>
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                <text>10.1371/journal.pone.0237626</text>
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                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Science, Medicine</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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      <elementSet elementSetId="1">
        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
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                <text>Comparison of viral and epidemiological profiles of hospitalized children with severe acute respiratory infection in Beijing and Shanghai, China</text>
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            <name>Creator</name>
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              <elementText elementTextId="18037">
                <text>Yanjie Zhao, Rou-Jian Lu, Jun Shen, Zhengde Xie, Gaoshan Liu, Wen-Jie Tan</text>
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            <description>An account of the resource</description>
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              <elementText elementTextId="18038">
                <text>Abstract Background No comparison data have been reported on viral and epidemiological profiles of hospitalized children with severe acute respiratory infection (SARI) in Beijing or Shanghai, China. Methods We collected 700 nasopharyngeal aspirates (NPA) from hospitalized children with SARI in Beijing (northern China) and Shanghai (southern China). Multiple respiratory viruses (including 15 common viruses) were screened by validated polymerase chain reaction (PCR) or real-time reverse transcription-PCR assays and confirmed by sequencing. Demographic data and the distribution of viral infections were also examined. Results Of 700 samples, 547 (78.1%) tested positive for viral infections. The picornaviruses (PIC), which included rhinovirus (RV) and enterovirus (EV), were the most common (34.0%), followed by respiratory syncytial virus (RSV) (28.3%), human bocavirus (HBoV) (19.1%), adenovirus (ADV) (13.7%), human coronaviruses (HCoV) (10.7%), influenza A and B (8.9%), parainfluenza virus (PIV 1–3) (7.9%), and human metapneumovirus (HMPV) (5.0%). PIC (RV/EV) and RSV were the most prevalent etiological agents of SARI in both cities. The total and age-matched prevalence of RSV, HCoV, and hMPV among SARI children under 5 years old were significantly higher in Beijing than in Shanghai. Different age and seasonal distribution patterns of the viral infections were found between Beijing and Shanghai. Conclusions Viral infection was tested and shown to be the most prevalent etiological agent among children with SARI in either the Beijing or the Shanghai area, while showing different patterns of viral and epidemiological profiles. Our findings provide a better understanding of the roles of geographic location and climate in respiratory viral infections in hospitalized children with SARI.</text>
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                <text>2019</text>
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            <name>Subject</name>
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                <text>Beijing, Children, Epidemiological Profile, Nasopharyngeal aspirates, Polymerase Chain Reaction, Severe Acute Respiratory Infection</text>
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                <text>DOI: 10.1186/s12879-019-4385-5</text>
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                <text>BMC Infectious Diseases</text>
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                <text>BMC</text>
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                <text>Infectious and parasitic diseases</text>
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                <text>EN</text>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
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                <text>Mental Health and Its Predictors during the Early Months of the COVID-19 Pandemic Experience in the United States</text>
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                <text>Yanmengqian Zhou, Erina  L. MacGeorge, Jessica  Gall Myrick</text>
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                <text>To date, there has been relatively little published research on the mental health impacts of COVID-19 for the general public at the beginning of the U.S.’ experience of the pandemic, or the factors associated with stress, anxiety, depression, and post-traumatic growth during this time. The current study provides a longitudinal examination of the predictors of self-reported stress, anxiety, depression, and post-traumatic growth for U.S. residents between April and May, 2020, including the influence of demographic, psychosocial, and behavioral factors on these outcomes. The findings indicate that, generally, the early months of the U.S. COVID-19 experience were characterized by a modest negative impact on mental health. Younger adults, people with pre-existing health conditions, and those experiencing greater perceived risk, higher levels of rumination, higher levels of co-rumination, greater social strain, or less social support reported worse mental health. Positive mental health was associated with the adoption of coping strategies, especially those that were forward-looking, and with greater adherence to national health-protection guidelines. The findings are discussed with regard to the current status of health-protective measures and mental health in the U.S., especially as these impact future management of the on-going pandemic.</text>
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                <text>mental health, covid-19, Depression, post-traumatic growth, longitudinal design, Anxiety and Stress Scale (DASS-21)</text>
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                <text>10.3390/ijerph17176315</text>
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                <text>Korean Society of Epidemiology</text>
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                <text>Outpatient strategies and the changing SARS-CoV-2 epidemic</text>
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                <text>Yanqiu Wei, Gang Li, Juan Li, Jiaojiao Chu, Huihui Yue, Fengqin Zhang, Huilan Zhang</text>
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                <text>10.1183/23120541.00111-2020</text>
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            <name>Title</name>
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                <text>The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak – an update on the status</text>
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            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
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              <elementText elementTextId="13407">
                <text>Yanrong Guo, Qing-Dong Cao, Zhongsi Hong, Yuan-Yang Tan, Shoudeng Chen, Hongjun Jin, Kai Sen Tan, Deyun Wang, Yan Yan</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>Abstract An acute respiratory disease, caused by a novel coronavirus (SARS-CoV-2, previously known as 2019-nCoV), the coronavirus disease 2019 (COVID-19) has spread throughout China and received worldwide attention. On 30 January 2020, World Health Organization (WHO) officially declared the COVID-19 epidemic as a public health emergency of international concern. The emergence of SARS-CoV-2, since the severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002 and Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012, marked the third introduction of a highly pathogenic and large-scale epidemic coronavirus into the human population in the twenty-first century. As of 1 March 2020, a total of 87,137 confirmed cases globally, 79,968 confirmed in China and 7169 outside of China, with 2977 deaths (3.4%) had been reported by WHO. Meanwhile, several independent research groups have identified that SARS-CoV-2 belongs to β-coronavirus, with highly identical genome to bat coronavirus, pointing to bat as the natural host. The novel coronavirus uses the same receptor, angiotensin-converting enzyme 2 (ACE2) as that for SARS-CoV, and mainly spreads through the respiratory tract. Importantly, increasingly evidence showed sustained human-to-human transmission, along with many exported cases across the globe. The clinical symptoms of COVID-19 patients include fever, cough, fatigue and a small population of patients appeared gastrointestinal infection symptoms. The elderly and people with underlying diseases are susceptible to infection and prone to serious outcomes, which may be associated with acute respiratory distress syndrome (ARDS) and cytokine storm. Currently, there are few specific antiviral strategies, but several potent candidates of antivirals and repurposed drugs are under urgent investigation. In this review, we summarized the latest research progress of the epidemiology, pathogenesis, and clinical characteristics of COVID-19, and discussed the current treatment and scientific advancements to combat the epidemic novel coronavirus.</text>
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                <text>2020</text>
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            <name>Subject</name>
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              <elementText elementTextId="13410">
                <text>clinical characteristics, Coronavirus disease 2019 (COVID-19), origin, SARS-CoV-2, therapy, Transmission</text>
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            <name>Identifier</name>
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              <elementText elementTextId="13411">
                <text>DOI: 10.1186/s40779-020-00240-0</text>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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              <elementText elementTextId="13412">
                <text>Military Medical Research</text>
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            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
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                <text>BMC</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Medicine (General), Military Science</text>
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            <name>Language</name>
            <description>A language of the resource</description>
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              <elementText elementTextId="13415">
                <text>EN</text>
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