2013 10 20655 https://www.socictopen.socict.org/files/original/a1cd7e8e52cccd5f892f0857af2ea70d.pdf 6ec2d43b021e357563788fdc4eae19c0 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Use of an Innovative Web-Based Laboratory Surveillance Platform to Analyze Mixed Infections Between Human Metapneumovirus (hMPV) and Other Respiratory Viruses Circulating in Alberta (AB), Canada (2009–2012) Creator An entity primarily responsible for making the resource Shamir Mukhi, Sumana Fathima, Jennifer May-Hadford, Bonita E Lee, Steven J. Drews Description An account of the resource We investigated the proportions of mono vs. mixed infections for human metapneumovirus (hMPV) as compared to adenovirus (ADV), four types of coronavirus (CRV), parainfluenza virus (PIV), RSV, and enterovirus/rhinovirus (ERV) in Alberta, Canada. Using the Data Integration for Alberta Laboratories (DIAL) platform, 26,226 respiratory specimens at ProvLab between 1 July 2009 and 30 June 2012 were selected and included in the study. Using the Respiratory Virus Panel these specimens tested positive for one or more respiratory virus and negative for influenza A and B. From our subset hMPV was the fourth most common virus (n=2,561) with 373 (15%) identified as mixed infection using DIAL. Mixed infection with hMPV was most commonly found in infants less than 6 months old and ERV was most commonly found in mixed infection with hMPV (230/373, 56%) across all age groups. The proportion of mixed-infection vs. mono-infection was highest for ADV (46%), followed by CRV 229E (32%), CRV HKU1 (31%), CRV NL63 (28%), CRV OC43 (23%), PIV (20%), RSV (17%), hMPV (15%) and ERV (13%). hMPV was significantly more likely to be identified in mono infection as compared with ADV, CRV, PIV, and RSV with the exception of ERV [p &lt; 0.05]. Date A point or period of time associated with an event in the lifecycle of the resource 2012 Subject The topic of the resource hMPV, co-infection, Testing, Epidemiology, respiratory Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/v4112754 Source A related resource from which the described resource is derived Viruses Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology Language A language of the resource EN https://www.socictopen.socict.org/files/original/3c8ce0b691525eeebaf1e3fe63e0c243.pdf 0aac79bff8a8a3bf859d2eb63a0a48c4 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Synthesis and Antimalarial Activity of Novel Dihydro-Artemisinin Derivatives Creator An entity primarily responsible for making the resource Jian Wang, Jin Huang, Chun Guo, Wei Luo, Yang Liu, Weiqiang Lu, Kunqiang Cui Description An account of the resource The Plasmodium falciparum cysteine protease falcipain-2, one of the most promising targets for antimalarial drug design, plays a key role in parasite survival as a major peptide hydrolase within the hemoglobin degradation pathway. In this work, a series of novel dihydroartemisinin derivatives based on (thio)semicarbazone scaffold were designed and synthesized as potential falcipain-2 inhibitors. The in vitro biological assay indicated that most of the target compounds showed excellent inhibition activity against P. falciparum falcipain-2, with IC50 values in the 0.29–10.63 μM range. Molecular docking studies were performed to investigate the binding affinities and interaction modes for the inhibitors. The preliminary SARs were summarized and could serve as a foundation for further investigation in the development of antimalarial drugs. Date A point or period of time associated with an event in the lifecycle of the resource 2011 Subject The topic of the resource falcipain-2 inhibitors, dihydroartemisinin derivatives, inhibition activity, molecular docking studies, SARS Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/molecules16064527 Source A related resource from which the described resource is derived Molecules Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Organic chemistry Language A language of the resource EN https://www.socictopen.socict.org/files/original/f16b641e89d2ef5697457e90f2fd3c17.pdf 8292793654e28a5c1b5c646e3e58d19d Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Performance Comparison between Steam Injected Gas Turbine and Combined Cycle during Frequency Drops Creator An entity primarily responsible for making the resource Saeed Bahrami, Ali Ghaffari, Magnus Genrup, Marcus Thern Description An account of the resource Single-shaft gas turbine and its cycles are sensitive to frequency drops and, therefore, sudden change loads or large frequency dips might affect their stability. This phenomenon is related to the reduction of the air mass flow passing through the machine during the frequency dips, which might lead to an interaction between governor and temperature control loop. In this paper, the performance of the combined cycle and steam-injected gas turbine are studied during frequency dips and transient maneuvers. For this purpose, two similar units are developed based on these cycles and their performances are studied in different scenarios. The simulation results show that the steam injected gas turbine has a better performance during frequency drops and it can handle relatively larger change loads. Date A point or period of time associated with an event in the lifecycle of the resource 2015 Subject The topic of the resource combined cycle, wet cycle, STIG turbine, frequency control Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/en8087582 Source A related resource from which the described resource is derived Energies Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Technology Language A language of the resource EN https://www.socictopen.socict.org/files/original/9a8ca27ac518bbd1df035eac6646599e.pdf 26306d4cda99996e6c9c7667c4944356 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Alphacoronaviruses Detected in French Bats Are Phylogeographically Linked to Coronaviruses of European Bats Creator An entity primarily responsible for making the resource Anne Goffard, Christine Demanche, Laurent Arthur, Claire Pinçon, Johan Michaux, Jean Dubuisson Description An account of the resource Bats are a reservoir for a diverse range of viruses, including coronaviruses (CoVs). To determine the presence of CoVs in French bats, fecal samples were collected between July and August of 2014 from four bat species in seven different locations around the city of Bourges in France. We present for the first time the presence of alpha-CoVs in French Pipistrellus pipistrellus bat species with an estimated prevalence of 4.2%. Based on the analysis of a fragment of the RNA-dependent RNA polymerase (RdRp) gene, phylogenetic analyses show that alpha-CoVs sequences detected in French bats are closely related to other European bat alpha-CoVs. Phylogeographic analyses of RdRp sequences show that several CoVs strains circulate in European bats: (i) old strains detected that have probably diverged a long time ago and are detected in different bat subspecies; (ii) strains detected in Myotis and Pipistrellus bat species that have more recently diverged. Our findings support previous observations describing the complexity of the detected CoVs in bats worldwide. Date A point or period of time associated with an event in the lifecycle of the resource 2015 Subject The topic of the resource bats, alphacoronavirus, coronavirus, phylogeographic analysis, Phylogenetic analysis, Europe, Molecular characterization Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/v7122937 Source A related resource from which the described resource is derived Viruses Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology Language A language of the resource EN https://www.socictopen.socict.org/files/original/46b381bbd285c2392e1da468c886cf8f.pdf ffbd1b12514275926c84b6f2381e5019 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Surface Segregation of Cyclic Chains in Binary Melts of Thin Polymer Films: The Influence of Constituent Concentration Creator An entity primarily responsible for making the resource Francis M. Gaitho, Mesfin Tsige, Genene T. Mola, Giuseppe Pellicane Description An account of the resource We carry out extensive molecular dynamics simulations of thin films of bead-spring models of binary mixtures composed of cyclic and linear polymer chains. We study the equilibrium behavior of the polymer chains for two very different chain lengths, which resemble short (10-mers) and long (100-mers) chains, at different concentrations of the binary mixture. We clearly show how the concentration variable affects the enrichment of either of the two polymer species at the interface, and also how the chain length influences this process. Date A point or period of time associated with an event in the lifecycle of the resource 2018 Subject The topic of the resource polymer melt, concentration, surface behavior, interface Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/polym10030324 Source A related resource from which the described resource is derived Polymers Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Organic chemistry Language A language of the resource EN https://www.socictopen.socict.org/files/original/376dc9729496bb4b84829cb94b41c5d3.pdf 9d8619bb361a8d0b7c6b4aafff8b733f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Detection of canine visceral leishmaniasis by conjunctival swab PCR Creator An entity primarily responsible for making the resource Vanessa Figueredo Pereira, Julia Cristina Benassi, Wilma Aparecida Starke Buzetti, Diogo Tiago Silva, Helena Lage Ferreira, Lara Borges Keid, Rodrigo Martins Soares, Vera Letticie de Azevedo Ruiz, Trícia Maria Ferreira de Sousa Oliveira Description An account of the resource Abstract: INTRODUCTION: Conjunctival swab PCR was evaluated as a tool to diagnose visceral leishmaniasis in dogs. METHODS: Conjunctival swab PCR was compared to indirect immunofluorescence antibody test and blood PCR. RESULTS: Indirect immunofluorescence was significantly correlated with conjunctival swab PCR (p < 0.05), but not with blood PCR (p > 0.05). In addition, conjunctival swab PCR was significantly associated with presence of clinical symptoms (p < 0.05), whereas blood PCR was associated with absence of clinical symptoms (p < 0.05). CONCLUSIONS: Results indicate that conjunctival swab PCR is useful in epidemiological surveys of canine visceral leishmaniasis. Date A point or period of time associated with an event in the lifecycle of the resource 2016 Subject The topic of the resource Canine visceral leishmaniasis, Conjunctival swab, Epidemiological survey Identifier An unambiguous reference to the resource within a given context DOI: 10.1590/0037-8682-0191-2015 Source A related resource from which the described resource is derived Revista da Sociedade Brasileira de Medicina Tropical Publisher An entity responsible for making the resource available Sociedade Brasileira de Medicina Tropical (SBMT) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Arctic medicine. Tropical medicine Language A language of the resource EN, ES, PT https://www.socictopen.socict.org/files/original/201a2810bdc42929a99bc8c1572c2515.pdf ad184c031fe409064531598d84de8c27 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A facile inhibitor screening of SARS coronavirus N protein using nanoparticle-based RNA oligonucleotide Creator An entity primarily responsible for making the resource Roh C Description An account of the resource Changhyun RohDivision of Biotechnology, Advanced Radiation Technology Institute (ARTI), Korea Atomic Energy Research Institute (KAERI), Jeongeup, Republic of KoreaAbstract: Hundreds of million people worldwide have been infected with severe acute respiratory syndrome (SARS), and the rate of global death from SARS has remarkably increased. Hence, the development of efficient drug treatments for the biological effects of SARS is highly needed. We have previously shown that quantum dots (QDs)-conjugated RNA oligonucleotide is sensitive to the specific recognition of the SARS-associated coronavirus (SARS-CoV) nucleocapsid (N) protein. In this study, we found that a designed biochip could analyze inhibitors of the SARS-CoV N protein using nanoparticle-based RNA oligonucleotide. Among the polyphenolic compounds examined, (-)-catechin gallate and (-)-gallocatechin gallate demonstrated a remarkable inhibition activity on SARS-CoV N protein. (-)-catechin gallate and (-)-gallocatechin gallate attenuated the binding affinity in a concentrated manner as evidenced by QDs-conjugated RNA oligonucleotide on a designed biochip. At a concentration of 0.05 &amp;micro;g mL&amp;ndash;1, (-)-catechin gallate and (-)-gallocatechin gallate showed more than 40% inhibition activity on a nanoparticle-based RNA oligonucleotide biochip system.Keywords: SARS, RNA oligonucleotide, quantum dots, inhibitor, screening Date A point or period of time associated with an event in the lifecycle of the resource 2012 Identifier An unambiguous reference to the resource within a given context DOI: Source A related resource from which the described resource is derived International Journal of Nanomedicine Publisher An entity responsible for making the resource available Dove Medical Press Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine (General) Language A language of the resource EN https://www.socictopen.socict.org/files/original/95d1b88e35678ee699c6b045c4e3ae6d.pdf 8ac9caa7780db749d12a188e9bd7b864 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource SARS: A need for Security Creator An entity primarily responsible for making the resource Mely Caballero-Anthony Date A point or period of time associated with an event in the lifecycle of the resource 2003 Identifier An unambiguous reference to the resource within a given context DOI: Source A related resource from which the described resource is derived Revista UNISCI Publisher An entity responsible for making the resource available UNISCI Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant International relations Language A language of the resource EN, ES https://www.socictopen.socict.org/files/original/a46e900886b6476cb8db3ccd1dea148b.pdf 2ec304d2f7446e2de059c4ffba430349 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource La neologia en societat: verba sequuntur"" Creator An entity primarily responsible for making the resource Judit Freixa Description An account of the resource Resum: El punt de partida d’aquest article és de caràcter social: els neologismes apareixen per referir-se a les novetats del món i a altres necessitats expressives dels parlants. Atès que els parlants consideren seva la llengua i emeten judicis poc contrastats sobre les paraules noves, en aquest article es discuteixen alguns dels interrogants més habituals sobre aquest tema: què és un neologisme?, hi ha neologismes més neològics que d’altres?, per què apareixen neologismes?, són tots igualment necessaris?, com són els neologismes del català?, el català crea neologismes o només els copia d’altres llengües? La conclusió de l’article és que el català, com qualsevol altra llengua viva, té creativitat lèxica i acull neologismes de tots tipus: estables i efímers, nous i vells, voluntaris i involuntaris, correctes i incorrectes, denominatius i expressius, ben formats i transgressors.Paraules clau: neologia lèxica, neologicitat, societat, creativitat lèxica, interferència lèxica. Date A point or period of time associated with an event in the lifecycle of the resource 2015 Subject The topic of the resource Neología léxica, neologicitat, societat, creativitat lèxica, interferència lèxica Identifier An unambiguous reference to the resource within a given context DOI: 10.7203/caplletra.59.6907 Source A related resource from which the described resource is derived Caplletra: Revista Internacional de Filologia Publisher An entity responsible for making the resource available Institut Interuniversitari de Filologia Valenciana (IIFV); Publicacions de l'Abadia de Montserrat (PAM) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Language and Literature, Philology. Linguistics Language A language of the resource CA, ES https://www.socictopen.socict.org/files/original/a5891e4c0d95fc971984c8177e0cad3c.pdf 852735caf87dd8eedba03d85532921a7 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Design, Synthesis, Activity and Docking Study of Sorafenib Analogs Bearing Sulfonylurea Unit Creator An entity primarily responsible for making the resource Chunjiang Wu, Min Wang, Qidong Tang, Rong Luo, Le Chen, Pengwu Zheng, Wufu Zhu Description An account of the resource Two series of novel sorafenib analogs containing a sulfonylurea unit were synthesized and their chemical structures were confirmed by 1H-NMR, 13C-NMR, MS spectrum and elemental analysis. The synthesized compounds were evaluated for the cytotoxicity against A549, Hela, MCF-7, and PC-3 cancer cell lines. Some of the compounds showed moderate cytotoxic activity, especially compounds 1-(2,4-difluorophenylsulfonyl)-3-(4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)urea (6c) and 1-(4-bromophenylsulfonyl)-3-(4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)urea (6f) with the IC50 values against four cancer cell lines ranging from 16.54 ± 1.22 to 63.92 ± 1.81 μM, respectively. Inhibitory rates against vascular endothelial growth factor receptor-2 (VEGFR2/KDR) kinase at 10 μM of target compounds were further carried out in this paper in order to investigate the target of these compounds. Structure-activity relationships (SARs) and docking studies indicated that the sulfonylurea unit was important to these kinds of compounds. None of the substitutions in the phenoxy group and small halogen atoms such as 2,4-difluoro substitution of the aryl group contributed to the activity. The results suggested that sulfonylurea sorafenib analogs are worthy of further study. Date A point or period of time associated with an event in the lifecycle of the resource 2015 Subject The topic of the resource Sorafenib, Sulfonylurea, VEGFR2/KDR kinase inhibitors, anti-cancer activity Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/molecules201019361 Source A related resource from which the described resource is derived Molecules Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Organic chemistry Language A language of the resource EN