2018 10 20655 https://www.socictopen.socict.org/files/original/e843f9a108b6cf05c40646c993fb3560.pdf f885f8f20fccb690959e717aa0757e5c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Peritonite infecciosa felina: 13 casos Feline infectious peritonitis: 13 cases Creator An entity primarily responsible for making the resource Fabiano Nunes de Oliveira, Margarida Buss Raffi, Tatiana Mello de Souza, Claudio Severo Lombardo de Barros Description An account of the resource Numa pesquisa realizada em tecidos de 638 gatos necropsiados, foram encontrados 13 casos (2,03%) de peritonite infecciosa felina. Oito desses casos (61,53%) eram da forma efusiva ou úmida, e 5 apresentavam a forma seca ou não-efusiva da doença. A idade dos gatos afetados variou de 2 meses a 3 anos. Doze gatos (92,30%) eram de raças puras, cinco deles (38,47%) eram oriundos de ambientes onde havia mais de um gato e três eram provenientes de um mesmo gatil. A duração da doença clínica foi de 7 a 45 dias e os sinais clínicos incluíram emagrecimento, anorexia, diarréia, icterícia, vômito, linfadenopatia e distúrbios neurológicos. Os achados de necropsia na forma úmida incluíam excesso de líquido viscoso (50ml a 1 litro), translúcido ou levemente opaco na cavidade peritoneal e, em um caso, na cavidade torácica. Exsudato fibrinoso cobria as superfícies serosas dos órgãos abdominais dando-lhes aspecto granular e brancacento. Na forma seca, havia múltiplos focos granulomatosos sob a superfície serosa e para o interior do parênquima de órgãos abdominais; esses achados eram particularmente proeminentes nos rins. Opacidade de córnea foi observada em um gato. Histologicamente, havia graus variáveis de vasculite e perivasculite piogranulomatosa, particularmente em arteríolas. Meningite ou meningoencefalite piogranulomatosa foram observadas em três gatos com a forma seca de peritonite infecciosa felina.In a survey carried out in tissue specimens from 638 necropsied cats, 13 cases (2.03%) of feline infectious peritonitis were found. Eight of those (61.53%) were of the effusive or wet form and five had the dry non-effusive form of the disease. Ages of affected cats varied from 2-months to 3 yeas. Twelve affected cats (92.30%) were purebreds, five of these cats (38.47%) came from households with more than one cat and three of them came from the same comercial cat raising facility. The duration of clinical courses were 7-45 days and clinical signs included loss of weight, anorexia, diarrhea, jaundice, vomiting, swollen lymph nodes, and neurological disturbances. Necropsy findings, in the wet form included excess of yellowish viscous tanslucent or slightly opaque fluid (50ml-1 liter) in the peritoneal cavity and (in one case) thoracic cavity. Fibrinous exudate covered the serosal surfaces of abdominal organs imparting a whitish, granular, frost-like appearance to them. In the dry form there were multiple granulomatous foci underneath the serosal surface, which extended into the parenchyma of abdominal organs; these findings were particularly prominent in the kidneys. Corneal opacity was observed in one cat. Histologically, there were variable degrees of disseminated piogranulomatous vasculitis and perivasculitis particularly in arterioles. Pyogranulomatous meningitis or meningoencephalitis were observed in three cats with the dry form of feline infectious peritonitis. Date A point or period of time associated with an event in the lifecycle of the resource 2003 Subject The topic of the resource peritonite infecciosa felina, doenças de gatos, doenças a vírus, coronavirus, patologia, feline infectious peritonitis, diseases of cats, viral diseases, pathology Identifier An unambiguous reference to the resource within a given context DOI: 10.1590/S0103-84782003000500018 Source A related resource from which the described resource is derived Ciência Rural Publisher An entity responsible for making the resource available Universidade Federal de Santa Maria Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Agriculture (General), Agriculture Language A language of the resource EN, PT https://www.socictopen.socict.org/files/original/b50f0ece6e3bde6e9ea916c44280939d.pdf 874f104f1be679606147e4e6eff27333 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Acute respiratory viral infections in pediatric cancer patients undergoing chemotherapy Creator An entity primarily responsible for making the resource Eliana C.A. Benites, Dayane P. Cabrini, Andrea C.B. Silva, Juliana C. Silva, Daniel T. Catalan, Eitan N. Berezin, Maria R.A. Cardoso, Saulo D. Passos Description An account of the resource OBJECTIVE: to estimate the prevalence of infection by respiratory viruses in pediatric patients with cancer and acute respiratory infection (ARI) and/or fever. METHODS: cross-sectional study, from January 2011 to December 2012. The secretions of nasopharyngeal aspirates were analyzed in children younger than 21 years with acute respiratory infections. Patients were treated at the Grupo em Defesa da Criança Com Câncer (Grendacc) and University Hospital (HU), Jundiaí, SP. The rapid test was used for detection of influenza virus (Kit Biotrin, Inc. Ireland), and real-time multiplex polymerase chain reaction (FTD, Respiratory pathogens, multiplex Fast Trade Kit, Malta) for detection of influenza virus (H1N1, B), rhinovirus, parainfluenza virus, adenovirus, respiratory syncytial virus, human parechovirus, bocavirus, metapneumovirus, and human coronavirus. The prevalence of viral infection was estimated and association tests were used (χ2 or Fisher's exact test). RESULTS: 104 samples of nasopharyngeal aspirate and blood were analyzed. The median age was 12 ± 5.2 years, 51% males, 68% whites, 32% had repeated ARIs, 32% prior antibiotic use, 19.8% cough, and 8% contact with ARIs. A total of 94.3% were in good general status. Acute lymphocytic leukemia (42.3%) was the most prevalent neoplasia. Respiratory viruses were detected in 50 samples: rhinoviruses (23.1%), respiratory syncytial virus AB (8.7%), and coronavirus (6.8%). Co-detection occurred in 19% of cases with 2 viruses and in 3% of those with 3 viruses, and was more frequent between rhinovirus and coronavirus 43. Fever in neutropenic patients was observed in 13%, of which four (30.7) were positive for viruses. There were no deaths. CONCLUSIONS: the prevalence of respiratory viruses was relevant in the infectious episode, with no increase in morbidity and mortality. Viral co-detection was frequent in patients with cancer and ARIs. Date A point or period of time associated with an event in the lifecycle of the resource 2014 Subject The topic of the resource cancer, Criança, virus, Infecções do trato respiratório Identifier An unambiguous reference to the resource within a given context DOI: 10.1016/j.jped.2014.01.006 Source A related resource from which the described resource is derived Jornal de Pediatria Publisher An entity responsible for making the resource available Elsevier Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Pediatrics Language A language of the resource EN https://www.socictopen.socict.org/files/original/102c147dcc1e578af04d12cb3f748c15.pdf 1929cffe429ef6706ac36ce50115fbb5 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource SARS-COV INDUCE L’ESPRESSIONE DI IFN-α E-γ IN PBMC DA DONATORI SANI ANCHE IN ASSENZA DI REPLICAZIONE VIRALE Creator An entity primarily responsible for making the resource C. Castilletti, L. Bordi, E. Lalle, G. Rozera, F. Poccia, C. Agrati, A. AbbateI, M.R. Capobianchi Description An account of the resource - Date A point or period of time associated with an event in the lifecycle of the resource 2005 Identifier An unambiguous reference to the resource within a given context DOI: 10.4081/mm.2005.3570 Source A related resource from which the described resource is derived Microbiologia Medica Publisher An entity responsible for making the resource available PAGEPress Publications Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology Language A language of the resource EN, IT https://www.socictopen.socict.org/files/original/bafbe274186056b582b1635345f77b24.pdf 5e9830c4d29819971fb4a2a2c56d4183 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Modified Vaccinia Virus Ankara (MVA) as Production Platform for Vaccines against Influenza and Other Viral Respiratory Diseases Creator An entity primarily responsible for making the resource Arwen F. Altenburg, Joost H. C. M. Kreijtz, Rory D. de Vries, Fei Song, Robert Fux, Guus F. Rimmelzwaan, Gerd Sutter, Asisa Volz Description An account of the resource Respiratory viruses infections caused by influenza viruses, human parainfluenza virus (hPIV), respiratory syncytial virus (RSV) and coronaviruses are an eminent threat for public health. Currently, there are no licensed vaccines available for hPIV, RSV and coronaviruses, and the available seasonal influenza vaccines have considerable limitations. With regard to pandemic preparedness, it is important that procedures are in place to respond rapidly and produce tailor made vaccines against these respiratory viruses on short notice. Moreover, especially for influenza there is great need for the development of a universal vaccine that induces broad protective immunity against influenza viruses of various subtypes. Modified Vaccinia Virus Ankara (MVA) is a replication-deficient viral vector that holds great promise as a vaccine platform. MVA can encode one or more foreign antigens and thus functions as a multivalent vaccine. The vector can be used at biosafety level 1, has intrinsic adjuvant capacities and induces humoral and cellular immune responses. However, there are some practical and regulatory issues that need to be addressed in order to develop MVA-based vaccines on short notice at the verge of a pandemic. In this review, we discuss promising novel influenza virus vaccine targets and the use of MVA for vaccine development against various respiratory viruses. Date A point or period of time associated with an event in the lifecycle of the resource 2014 Subject The topic of the resource modified Vaccinia virus Ankara, vaccine development, Influenza virus, Respiratory Syncytial Virus, parainfluenza virus, coronavirus Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/v6072735 Source A related resource from which the described resource is derived Viruses Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology Language A language of the resource EN https://www.socictopen.socict.org/files/original/46c3ace5891d77d7c3879d921ac9a6db.pdf 34964a621d5536712ba91771c1024da1 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Tetranucleotide usage highlights genomic heterogeneity among mycobacteriophages [version 2; referees: 2 approved] Creator An entity primarily responsible for making the resource Benjamin Siranosian, Sudheesha Perera, Edward Williams, Chen Ye, Christopher de Graffenried, Peter Shank Description An account of the resource Background The genomic sequences of mycobacteriophages, phages infecting mycobacterial hosts, are diverse and mosaic. Mycobacteriophages often share little nucleotide similarity, but most of them have been grouped into lettered clusters and further into subclusters. Traditionally, mycobacteriophage genomes are analyzed based on sequence alignment or knowledge of gene content. However, these approaches are computationally expensive and can be ineffective for significantly diverged sequences. As an alternative to alignment-based genome analysis, we evaluated tetranucleotide usage in mycobacteriophage genomes. These methods make it easier to characterize features of the mycobacteriophage population at many scales. Description We computed tetranucleotide usage deviation (TUD), the ratio of observed counts of 4-mers in a genome to the expected count under a null model. TUD values are comparable between members of a phage subcluster and distinct between subclusters. With few exceptions, neighbor joining phylogenetic trees and hierarchical clustering dendrograms constructed using TUD values place phages in a monophyletic clade with members of the same subcluster. Regions in a genome with exceptional TUD values can point to interesting features of genomic architecture. Finally, we found that subcluster B3 mycobacteriophages contain significantly overrepresented 4-mers and 6-mers that are atypical of phage genomes. Conclusions Statistics based on tetranucleotide usage support established clustering of mycobacteriophages and can uncover interesting relationships within and between sequenced phage genomes. These methods are efficient to compute and do not require sequence alignment or knowledge of gene content. The code to download mycobacteriophage genome sequences and reproduce our analysis is freely available at https://github.com/bsiranosian/tango_final. Date A point or period of time associated with an event in the lifecycle of the resource 2015 Subject The topic of the resource Bioinformatics, Genomics Identifier An unambiguous reference to the resource within a given context DOI: 10.12688/f1000research.6077.2 Source A related resource from which the described resource is derived F1000Research Publisher An entity responsible for making the resource available F1000 Research Ltd Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General), Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/87736d21fa7962b205a9fa0db62c007e.pdf bf9dae51e29d4e74f6b16572bea0eeff Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Genome-wide analysis of DNA methylation, copy number variation, and gene expression in monozygotic twins discordant for primary biliary cirrhosis Creator An entity primarily responsible for making the resource Carlo eSelmi, Francesca eCavaciocchi, Ana eLleo, Cristina eCheroni, Raffaele eDe Francesco, Simone A. Lombardi, Maria eDe Santis, Francesca eMeda, Maria Gabriella eRaimondo, Chiara eCrotti, Marco eFolci, Luca eZammataro, Marlyn J. Mayo, Nancy eBach, Shinji eShimoda, Stuart eGordon, Monica eMiozzo, Pietro eInvernizzi, Mauro ePodda, Rossana eScavelli, Michelle R. Martin, Michael Forrest Seldin, Janine M. LaSalle, M. Eric eGershwin Description An account of the resource Primary biliary cirrhosis (PBC) is an uncommon autoimmune disease with a homogeneous clinical phenotype that reflects incomplete disease concordance in monozygotic (MZ) twins. We have taken advantage of a unique collection consisting of genomic DNA and mRNA from peripheral blood cells of female MZ twins (n=3 sets) and sisters of similar age (n=8 pairs) discordant for disease. We performed a genome-wide study to investigate differences in (i) DNA methylation (using a custom tiled 4-plex array containing tiled 50-mers 19,084 randomly chosen methylation sites), (ii) copy number variation (CNV) (with a chip including markers derived from the 1000 Genomes Project, all three HapMap phases, and recently published studies), and/or (iii) gene expression (by whole-genome expression arrays). Based on the results obtained from these three approaches we utilized quantitative PCR to compare the expression of candidate genes. Importantly, our data support consistent differences in discordant twins and siblings for the (i) methylation profiles of 60 gene regions, (ii) CNV of 10 genes, and (iii) the expression of 2 interferon-dependent genes. Quantitative PCR analysis showed that 17 of these genes are differentially expressed in discordant sibling pairs. In conclusion, we report that MZ twins and sisters discordant for PBC manifest particular epigenetic differences and highlight the value of the epigenetic study of twins. Date A point or period of time associated with an event in the lifecycle of the resource 2014 Subject The topic of the resource twins, Monozygotic, epigenetics, Primary biliary cirrhosis, environment, Autoimmune cholangitis Identifier An unambiguous reference to the resource within a given context DOI: 10.3389/fimmu.2014.00128 Source A related resource from which the described resource is derived Frontiers in Immunology Publisher An entity responsible for making the resource available Frontiers Media S.A. Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Immunologic diseases. Allergy Language A language of the resource EN https://www.socictopen.socict.org/files/original/87fba88a3549a34297fb93fe087bca40.pdf a43f859965f919d36960fa30ab12572b Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Molecular Characterization of Major Structural Protein Genes of Avian Coronavirus Infectious Bronchitis Virus Isolates in Southern China Creator An entity primarily responsible for making the resource Mei-Lan Mo, Meng Li, Bai-Cheng Huang, Wen-Sheng Fan, Ping Wei, Tian-Chao Wei, Qiu-Ying Cheng, Zheng-Ji Wei, Ya-Hui Lang Description An account of the resource To gain comprehensive genetic information of circulating avian coronavirus infectious bronchitis virus (IBV) isolates in China, analysis of the phylogenetic tree, entropy of the amino acid sequences, and the positive selection as well as computational recombinations of S1, M and N genes of 23 IBV isolates was conducted in the present study. The phylogenetic trees based on the S1, M and N genes exhibited considerably different topology and the CK/CH/LSC/99I-type isolates were the predominant IBVs based on the phylogenetic analysis of S1 gene. Results of entropy of amino acid sequences revealed that the S1 gene had the largest variation; the M gene had less variation than the N gene. Positive selections were detected in not only S1 but also M and N gene proteins. In addition, five S1 gene recombinants between vaccine strain 4/91 and CK/CH/LSC/99I-type field isolate were confirmed. In conclusion, multiple IBV genotypes co-circulated; genetic diversity and positive selections existed in S1, M and N genes; 4/91 vaccine recombinants emerged in China. Our results show that field IBVs in China are continuing to evolve and vaccine strains may have an important role in the appearance of new IBV strains via recombination. In addition, the present study indicates that IBV evolution is driven by both generations of genetic diversity and selection. Date A point or period of time associated with an event in the lifecycle of the resource 2013 Subject The topic of the resource infectious bronchitis virus, Genetic variation, phylogenetic tree, Entropy, Positive selection, recombination Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/v5123007 Source A related resource from which the described resource is derived Viruses Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology Language A language of the resource EN https://www.socictopen.socict.org/files/original/b2e3ea19a1a90d336471ead2ab693db8.pdf 683080d4dbe804dea16bb8763f5a8bba Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Nuove strategie per la prevenzione Creator An entity primarily responsible for making the resource V. Carreri Description An account of the resource 1. Premessa: il 2003 è iniziato con la guerra in Iraq che ha reso precaria la sopravvivenza dell’ONU, quando i rapporti internazionali dovrebbero essere fondamentali per uniformare i livelli di qualità della vita e della salute. La vicenda della Sindrome Respiratoria Acuta Severa (SARS) ha confermato la globalizzazione di alcune epidemie. Questi eventi hanno rilanciato tematiche di interesse ed attualità, alcune negative come la guerra e il bioterrorismo, altre positive come la dimostrazione dell’efficacia di un intervento internazionale coordinato. 2. Lo stato della prevenzione: non mancano esperienze positive, soprattutto dove il mondo dei Servizi collabora con Università e centri di ricerca. L’invecchiamento della popolazione impone nuove strategie per la educazione sanitaria e la prevenzione, mentre ancora limitati sono gli interventi per contenere le malattie di maggior rilevanza sociale. Date A point or period of time associated with an event in the lifecycle of the resource 2003 Identifier An unambiguous reference to the resource within a given context DOI: 10.2427/6040 Source A related resource from which the described resource is derived Italian Journal of Public Health Publisher An entity responsible for making the resource available Prex spa Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Public aspects of medicine, Medicine Language A language of the resource ENGLISH https://www.socictopen.socict.org/files/original/2d9ae224f35ee225c7aa1ba1a3405036.pdf a8a10f4c937982a207a73ace2bf13479 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Middle East respiratory syndrome coronavirus: epidemiology and disease control measures Creator An entity primarily responsible for making the resource Al-Tawfiq JA, Memish ZA Description An account of the resource Jaffar A Al-Tawfiq,1,2 Ziad A Memish3,4 1Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia; 2Indiana University School of Medicine, Indianapolis, IN, USA; 3Ministry of Health, 4Alfaisal University, Riyadh, Saudi Arabia Abstract: The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in 2012 resulted in an increased concern of the spread of the infection globally. MERS-CoV infection had previously caused multiple health-care-associated outbreaks and resulted in transmission of the virus within families. Community onset MERS-CoV cases continue to occur. Dromedary camels are currently the most likely animal to be linked to human MERS-CoV cases. Serologic tests showed significant infection in adult camels compared to juvenile camels. The control of MERS-CoV infection relies on prompt identification of cases within health care facilities, with institutions applying appropriate infection control measures. In addition, determining the exact route of transmission from camels to humans would further add to the control measures of MERS-CoV infection. Keywords: MERS, Middle East respiratory syndrome coronavirus, epidemiology, control measures, transmission, Saudi Arabia Date A point or period of time associated with an event in the lifecycle of the resource 2014 Identifier An unambiguous reference to the resource within a given context DOI: Source A related resource from which the described resource is derived Infection and Drug Resistance Publisher An entity responsible for making the resource available Dove Medical Press Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases Language A language of the resource EN https://www.socictopen.socict.org/files/original/97b1b5df1779fb5b5587109b80e6db33.pdf 49443c7e11dc36ea14c893afc7660cb3 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource SLOWLY ADAPTING SENSORY UNITS HAVE MORE RECEPTORS IN LARGE AIRWAYS THAN IN SMALL AIRWAYS IN RABBITS Creator An entity primarily responsible for making the resource Jun Liu, Nana Song, Juan Guardiola, Jesse Roman, Jerry Yu Description An account of the resource Sensory units of pulmonary slowly adapting receptors (SARs) are more active in large airways than in small airways. However, there is no explanation for this phenomenon. Although sensory structures in large airways resemble those in small airways, they are bigger and more complex. Possibly, a larger receptor provides greater surface area for depolarization, and thus has a lower activating threshold and/or a higher sensitivity to stretch, leading to more nerve electrical activities. Recently, a single sensory unit has been reported to contain multiple receptors. Therefore, sensory units in large airways may contain more SARs, which may contribute to high activities. To test this hypothesis, we used a double staining technique to identify sensory receptor sizes. We labeled the sensory structure with Na+/K+-ATPase antibodies and the myelin sheath with myelin basic protein (MBP) antibodies. A SAR can be defined as the end formation beyond MBP labeling. Thus, we are able to compare sizes of sensory structures and SARs in large (trachea and bronchi) vs small (bronchioles Date A point or period of time associated with an event in the lifecycle of the resource 2016 Subject The topic of the resource Sensory Receptor Cells, Vagus Nerve, vagal afferents, Airway receptors, Lung afferents, sensory unit Identifier An unambiguous reference to the resource within a given context DOI: 10.3389/fphys.2016.00588 Source A related resource from which the described resource is derived Frontiers in Physiology Publisher An entity responsible for making the resource available Frontiers Media S.A. Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Physiology Language A language of the resource EN