2027 10 20655 https://www.socictopen.socict.org/files/original/3b93fa599717d402cb086a9df5f7f893.pdf 386eb84a5002ce3a52d424af004d521c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A Unified Framework for the Infection Dynamics of Zoonotic Spillover and Spread. Creator An entity primarily responsible for making the resource Giovanni Lo Iacono, Andrew A. Cunningham, Elisabeth Fichet-Calvet, Robert F. Garry, Donald S. Grant, Melissa Leach, Lina M. Moses, Gordon Nichols, John S. Schieffelin, Jeffrey G. Shaffer, Colleen T. Webb, James L.N. Wood Description An account of the resource A considerable amount of disease is transmitted from animals to humans and many of these zoonoses are neglected tropical diseases. As outbreaks of SARS, avian influenza and Ebola have demonstrated, however, zoonotic diseases are serious threats to global public health and are not just problems confined to remote regions. There are two fundamental, and poorly studied, stages of zoonotic disease emergence: 'spillover', i.e. transmission of pathogens from animals to humans, and 'stuttering transmission', i.e. when limited human-to-human infections occur, leading to self-limiting chains of transmission. We developed a transparent, theoretical framework, based on a generalization of Poisson processes with memory of past human infections, that unifies these stages. Once we have quantified pathogen dynamics in the reservoir, with some knowledge of the mechanism of contact, the approach provides a tool to estimate the likelihood of spillover events. Comparisons with independent agent-based models demonstrates the ability of the framework to correctly estimate the relative contributions of human-to-human vs animal transmission. As an illustrative example, we applied our model to Lassa fever, a rodent-borne, viral haemorrhagic disease common in West Africa, for which data on human outbreaks were available. The approach developed here is general and applicable to a range of zoonoses. This kind of methodology is of crucial importance for the scientific, medical and public health communities working at the interface between animal and human diseases to assess the risk associated with the disease and to plan intervention and appropriate control measures. The Lassa case study revealed important knowledge gaps, and opportunities, arising from limited knowledge of the temporal patterns in reporting, abundance of and infection prevalence in, the host reservoir. Date A point or period of time associated with an event in the lifecycle of the resource 2016 Identifier An unambiguous reference to the resource within a given context DOI: 10.1371/journal.pntd.0004957 Source A related resource from which the described resource is derived PLoS Neglected Tropical Diseases Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Arctic medicine. Tropical medicine, Public aspects of medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/7e0fe4062a1accf4cc441325c3f8e492.pdf 8718b7b45c70ade1e591de086d10fd64 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Molecular Design, Synthesis and Trypanocidal Activity of Dipeptidyl Nitriles as Cruzain Inhibitors. Creator An entity primarily responsible for making the resource Leandro A A Avelar, Cristian D Camilo, Sérgio de Albuquerque, William B Fernandes, Cristiana Gonçalez, Peter W Kenny, Andrei Leitão, James H. McKerrow, Carlos A. Montanari, Erika V Meñaca Orozco, Jean F R Ribeiro, Josmar R Rocha, Fabiana Rosini, Marta E Saidel Description An account of the resource A series of compounds based on the dipeptidyl nitrile scaffold were synthesized and assayed for their inhibitory activity against the T. cruzi cysteine protease cruzain. Structure activity relationships (SARs) were established using three, eleven and twelve variations respectively at the P1, P2 and P3 positions. A Ki value of 16 nM was observed for the most potent of these inhibitors which reflects a degree of non-additivity in the SAR. An X-ray crystal structure was determined for the ligand-protein complex for the structural prototype for the series. Twenty three inhibitors were also evaluated for their anti-trypanosomal effects and an EC50 value of 28 μM was observed for the most potent of these. Although there remains scope for further optimization, the knowledge gained from this study is also transferable to the design of cruzain inhibitors based on warheads other than nitrile as well as alternative scaffolds. Date A point or period of time associated with an event in the lifecycle of the resource 2015 Identifier An unambiguous reference to the resource within a given context DOI: 10.1371/journal.pntd.0003916 Source A related resource from which the described resource is derived PLoS Neglected Tropical Diseases Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Arctic medicine. Tropical medicine, Public aspects of medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/128e08784f0d162a0d2a012fd3381409.pdf 6f00e41f767607d1c0ef49870bf019cb Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Increased breadth and depth of cytotoxic T lymphocytes responses against HIV-1-B Nef by inclusion of epitope variant sequences. Creator An entity primarily responsible for making the resource Morgane Rolland, Nicole Frahm, David C. Nickle, Nebojsa Jojic, Wenjie Deng, Todd M. Allen, Christian Brander, David E Heckerman, James I. Mullins Description An account of the resource Different vaccine approaches cope with HIV-1 diversity, ranging from centralized(1-4) to variability-encompassing(5-7) antigens. For all these strategies, a concern remains: how does HIV-1 diversity impact epitope recognition by the immune system? We studied the relationship between HIV-1 diversity and CD8(+) T Lymphocytes (CTL) targeting of HIV-1 subtype B Nef using 944 peptides (10-mers overlapping by nine amino acids (AA)) that corresponded to consensus peptides and their most common variants in the HIV-1-B virus population. IFN-γ ELISpot assays were performed using freshly isolated PBMC from 26 HIV-1-infected persons. Three hundred and fifty peptides elicited a response in at least one individual. Individuals targeted a median of 7 discrete regions. Overall, 33% of responses were directed against viral variants but not elicited against consensus-based test peptides. However, there was no significant relationship between the frequency of a 10-mer in the viral population and either its frequency of recognition (Spearman's correlation coefficient ρ = 0.24) or the magnitude of the responses (ρ = 0.16). We found that peptides with a single mutation compared to the consensus were likely to be recognized (especially if the change was conservative) and to elicit responses of similar magnitude as the consensus peptide. Our results indicate that cross-reactivity between rare and frequent variants is likely to play a role in the expansion of CTL responses, and that maximizing antigenic diversity in a vaccine may increase the breadth and depth of CTL responses. However, since there are few obvious preferred pathways to virologic escape, the diversity that may be required to block all potential escape pathways may be too large for a realistic vaccine to accommodate. Furthermore, since peptides were not recognized based on their frequency in the population, it remains unclear by which mechanisms variability-inclusive antigens (i.e., constructs enriched with frequent variants) expand CTL recognition. Date A point or period of time associated with an event in the lifecycle of the resource 2011 Identifier An unambiguous reference to the resource within a given context DOI: 10.1371/journal.pone.0017969 Source A related resource from which the described resource is derived PLoS ONE Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Science, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/b217b656dcadc828be3346e1bbe83194.pdf 63059ddc0094fe27e6be8eb116a56314 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource The Important Role of Lipid Raft-Mediated Attachment in the Infection of Cultured Cells by Coronavirus Infectious Bronchitis Virus Beaudette Strain. Creator An entity primarily responsible for making the resource Hui-Chen Guo, Mei Huang, Quan Yuan, Yanquan Wei, Yuan Gao, Lejiao Mao, Lingjun Gu, Yong Wah Tan, Yanxin Zhong, Ding Xiang Liu, Shiqi Sun Description An account of the resource Lipid raft is an important element for the cellular entry of some viruses, including coronavirus infectious bronchitis virus (IBV). However, the exact role of lipid rafts in the cellular membrane during the entry of IBV into host cells is still unknown. In this study, we biochemically fractionated IBV-infected cells via sucrose density gradient centrifugation after depleting plasma membrane cholesterol with methyl-β-cyclodextrin or Mevastatin. Our results demonstrated that unlike IBV non-structural proteins, IBV structural proteins co-localized with lipid raft marker caveolin-1. Infectivity assay results of Vero cells illustrated that the drug-induced disruption of lipid rafts significantly suppressed IBV infection. Further studies revealed that lipid rafts were not required for IBV genome replication or virion release at later stages. However, the drug-mediated depletion of lipid rafts in Vero cells before IBV attachment significantly reduced the expression of viral structural proteins, suggesting that drug treatment impaired the attachment of IBV to the cell surface. Our results indicated that lipid rafts serve as attachment factors during the early stages of IBV infection, especially during the attachment stage. Date A point or period of time associated with an event in the lifecycle of the resource 2017 Identifier An unambiguous reference to the resource within a given context DOI: 10.1371/journal.pone.0170123 Source A related resource from which the described resource is derived PLoS ONE Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Science, Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/7a23d36c6336b6e71a6a2319aac47ed5.pdf 7bd064dfe7797b6816b7b19317b1691c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource One health: The interface between veterinary and human health Creator An entity primarily responsible for making the resource Kshitiz Shrestha, Krishna Prasad Acharya, Sujan Shrestha Description An account of the resource One Health is an emerging global key concept integrating human and animal health through international research and policy. The complex relationships between the human and animal have resulted in a human-animal-environment interface since prehistorical times. The people, animals, plants, and the environment are so intrinsically linked that prevention of risks and the mitigation of effects of crises that originate at the interface between humans, animals, and their environments can only improve health and wellbeing. The “One Health” approach has been successfully implemented in numerous projects around the world. The containment of pandemic threats such as avian influenza and severe acute respiratory syndrome within months of outbreak are few examples of successful applications of the One Health paradigm. The paper begins with a brief overview of the human-animal interface and continues with the socio-economic and public health impact caused by various zoonotic diseases such as Middle East respiratory syndrome, Influenza, and Ebola virus. This is followed by the role of “One Health” to deal the global problem by the global solution. It emphasizes the interdisciplinary collaboration, training for health professionals and institutional support to minimize global health threats due to infectious diseases. The broad definition of the concept is supposed to lead multiple interpretations that impede the effective implementation of One Health approach within veterinary profession, within the medical profession, by wildlife specialists and by environmentalists, while on the other side, it gives a value of interdisciplinary collaboration for reducing threats in human-animal-environment interface. Date A point or period of time associated with an event in the lifecycle of the resource 2018 Subject The topic of the resource emerging infectious diseases, One Health, viral zoonoses Identifier An unambiguous reference to the resource within a given context DOI: 10.14202/IJOH.2018.8-14 Source A related resource from which the described resource is derived International Journal of One Health Publisher An entity responsible for making the resource available Veterinary World Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine (General), Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/088efe6e197ffea0aefc93a9082f5edb.pdf 485ad0f2069623eaaa6ef16304be606d Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource With Father Dumitru Stăniloae on Father Dumitru Stăniloae Creator An entity primarily responsible for making the resource Florin Grigorescu Description An account of the resource Studiul „Cu Părintele Dumitru Stăniloae despre Părintele Dumitru Stăniloae” reprezintă o incursiune sumară în biografia şi opera celui care este considerat pe bună dreptate cel mai mare teolog al secolului al XX-lea. Titlul sus-menţionat a fost dat de consistentele mărturii pe care Părintele Stăniloae le-a lăsat cu privire la traiul său personal şi public, cu privire la spaţiul familial propriu şi cu privire la amănuntele alcătuirii operei sale – mărturii pe care le-am folosit cu predilecţie pentru a-i contura în linii succinte personalitatea.Ceea ce Părintele Stăniloae a creat şi a lăsat posterităţii deschide o poartă pentru aproape toate ramurile cercetării: teologie, istorie, filozofie, sociologie, jurnalistică, artă, literatură şi chiar economie. Istoricul ardelean Mircea Păcurariu a iniţiat conceptul de „epocă Dumitru Stăniloae în teologia românească”, mărturisind în acelaşi timp că „o evaluare a muncii acestui titan al teologiei şi gândirii româneşti contemporane e greu de făcut”, „o judecată obiectivă urmând a o face, în timp, istoria”.Legăturile cu mii de fire pe care Părintele Stăniloae le-a avut cu naţiunea română, cu dreapta credinţă a strămoşilor săi şi cu tradiţiile sfinte ale românilor sunt principalele coordonate prin care s-a dezvoltat personalitatea Părintelui Dumitru, coordonate pe baza cărora s-a mers şi în alcătuirea studiului prezent.„Epoca” Stăniloae continuă acum prin necontenita aprofundare a scrierilor şi mărturiilor Sfinţiei Sale şi înveşniceşte istoric cei peste 65 de ani strădanii cărturăreşti şi duhovniceşti şi cei 90 de ani de exponenţială mărturisire Ortodoxă la superlativ a „minunii Stăniloae”.Studiul „Cu Părintele Dumitru Stăniloae despre Părintele Dumitru Stăniloae” se constituie ca o parte a lucrării de doctorat „Personalităţi ale Bisericii Ortodoxe Române contemporane. Dumitru Stăniloae” – începută la Universitatea „Ştefan cel Mare” din Suceava, secţia Istorie, sub conducerea profesorului universitar doctor Mihai Iacobescu. Date A point or period of time associated with an event in the lifecycle of the resource 2006 Identifier An unambiguous reference to the resource within a given context DOI: Source A related resource from which the described resource is derived Codrul Cosminului Publisher An entity responsible for making the resource available Stefan cel Mare University of Suceava Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant History (General) Language A language of the resource DE, EN, FR, RU https://www.socictopen.socict.org/files/original/5f8fab55cd1c70b82a96e64f25d1d002.pdf b62164fa4b50b434ca8bf7743899bec2 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Acinar Adenocarcinoma of Prostate with Predominant Ttf-1 Positive Intraductal Component Creator An entity primarily responsible for making the resource Banu Sarsık, Nisar KARADENİZ, Adnan Simsir, Rahmi AKYOL, Kutsal Yörükoğlu, Sait Sen Description An account of the resource Intraductal carcinoma of prostate has been previously described in radical prostatectomies. It’s rarely encountered in needle biopsies in the absence of infiltrative carcinoma. But, both histogenesis and nomenclature of the lesion is still controversial. Among the pure intraductal carcinoma of prostate cases, a different solid patern was described with smaller nuclei at the center of the ducts. However, there is a lack of information about the association of those cases with acinar prostate adenocarcinoma. Herein, we describe a case of acinar adenocarcinoma with predominant non-neuroendocrine TTF-1 positive small cell intraductal component. Date A point or period of time associated with an event in the lifecycle of the resource 2017 Subject The topic of the resource Prostate Neoplasms, ductal carcinoma, Thyroid transcription factor 1 Identifier An unambiguous reference to the resource within a given context DOI: 10.5146/tjpath.2014.01253 Source A related resource from which the described resource is derived Türk Patoloji Dergisi Publisher An entity responsible for making the resource available Federation of Turkish Pathology Societies Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Pathology Language A language of the resource EN https://www.socictopen.socict.org/files/original/9b26ef28b9207dfdee6621a97fd43be3.pdf 6802556e1e4020a6de28e29d39baf413 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource New Data on Biota of Some Lakes in the Western Part of the Putorana Plateau Creator An entity primarily responsible for making the resource Vladimir A. Zadelenov, Olga P. Dubovskaya, Lilya V. Bazhina, Larisa A. Glushchenko, Inara G. Isaeva, Valentina O. Kleush, Kseniya A. Semenchenko, Viktor V. Matasov, Evgeniy N. Shadrin Description An account of the resource Species composition and abundance of zooplankton and zoobenthos of large Norilsk Lakes (Lama, Sobach’e) and Kutaramakan Lake in the western part of the Putorana plateau were studied in August-September of 2013–2014 after a long gap. Senecella calanoides Juday (Copepoda: Calanoida) in zooplankton and 5 species of water mites (Acalyptonotus violaceus Walter, Hygrobates (Hygrobates) foreli (Lebert), Lebertia (Mixolebertia) densa Koenike, Lebertia (Pilolebertia) porosa Thor, Oxus (Gnaphiscus) setosus (Koenike) (Hydrachnidia)) in zoobenthos were recorded for the first time in the investigated lakes. A total of 64 taxa of benthic invertebrates were found, of which 42 taxa were Chironomidae. Zooplankton species composition of Lama and Cobach’e lakes was similar and differed from that of Kutaramakan lake by presence of Senecella calanoides and Limnocalanus macrurus Sars (Copepoda: Calanoida). In zoobenthos of Kutaramakan lake amphipods were not found. Lama and Kutaramakan lakes can be classified as ultraoligotrophic water bodies based on biomass of zooplankton and zoobenthos. Among the studied lakes, Cobach’e lake has the greatest biomass, and based on the biomass of zooplankton in some zones of > 0.5 g/m3, it is an oligotrophic water body, and based on an average biomass of zoobenthos 3.85 g/m2 an α-mesotrophic one Date A point or period of time associated with an event in the lifecycle of the resource 2017 Subject The topic of the resource zooplankton, Zoobenthos, lake, LAMA, Sobach’e, Kutaramakan Identifier An unambiguous reference to the resource within a given context DOI: Source A related resource from which the described resource is derived Журнал Сибирского федерального университета: Серия Биология Publisher An entity responsible for making the resource available Siberian Federal University Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General), Biotechnology Language A language of the resource EN, RU https://www.socictopen.socict.org/files/original/2b185d18ca388920e572686ed5c79293.pdf 69922608d1ba86fb0e7a42c8f254765a Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource RIJEKA ZETA KAO POTENCIJAL ZA RAZVOJ SPORTSKO-REKREATIVNIH OBLIKA TURIZMA Creator An entity primarily responsible for making the resource Ognjen Jovović Description An account of the resource Ba sic for re a li za tion of to u rist mo ve ments lays in me e ting cul tu ral and rec re a ti onal ne eds of po ten tial cu sto mers. If we know that lar gest num ber of to u rists re pre sents part of rec re a ti o nal ones, than is not hard to re a li ze how lar ge po ten tial lays in that number of po ten tial gu ests. On this fact sho uld be bu ilt stra tegy of mo ve ment of to u rist of fer of Da ni lov grad for it ex tre me po ten ti als on which can be fo un ded con cre te pro ject. In this work are gi ven ba sic as sump ti ons for de ve lop ment of sport rec re a ti o nal sha pes of to u rism with stress to na tu ral po ten ti als of ri ver Ze ta its banks and its clo se sur ro un ding that di rectly de ter mine sha pe of sport rec re a ti o nal ac ti vi ti es that re pre sent ba sis of to u rist of fer. Of fer sho uld be cre a ted in that way that it is adap ted to wi de seg ment of rec re a ti o nal gu ests and not pro fes si o nal spor tsmen, alt ho ugh they al so sho uld not be un de re sti ma ted but one sho uld know that in or der to cre a te con di ti ons for ar ri val of sports pro fes si o nals of fer has to be com ple tely dif fe rent and mo re spe ci a li zed that re qu i res cre a ting of con di ti ons of existen ce of highly de ve lo ped sports in fra struc tu re, whi le for ama te urs a lot can be do ne in “system of im pro vi sing”, sa tisfying ba sic cri te ria – rec re a tion in con di ti ons of un touc hed and well pre ser ved na tu re with se cu ring ma xi mal le vel of se cu rity and pro tec tion of gu ests, in or der to pre vent pos si ble un wil ling con se qu en ces that can lead to in jury of gu ests and for de ve lop ment and re a li za tion of such pro ject one need a much less funds than is bu il ding of fa ci li ti es that sho uld me et stan dards of pro fes si o nal spor tsmen. Po ten tial of ri ver Ze ta are hu ge and at trac ti ve for which re pre sent na tu ral re so urce on which can be fo un ded pro jects of de ve lop ment of sports rec re a ti o nal to u rism thatha ve all advan ta ges that along cre a ting cer tain to u rist pro grams, the ir good pro mo tion and be co ming fa mi li ar with po ten tial gu ests with its con tents so that they can be co me highly qu a li ta ti ve ba sis for eco no mic de ve lop ment of Da ni lov grad. The aim is to cre a te good of fer at good in fra struc tu re, lo gi stics and with good equip ment with se cu ring ma xi mal se cu rity, adap ta tion to va ri o us wis hes of gu ests, ta king in con si de ra tion the ir struc tu re is con di ti o ned by age, he alth con di tion, physi cal fi t ness as per so nal wis hes to ward sports and rec re a ti o nal ac ti vi ti es. Date A point or period of time associated with an event in the lifecycle of the resource 2007 Subject The topic of the resource ri ver Ze ta, tourist needs, sports recreational tourism, untouched and preserved nature, safety of guests, development Identifier An unambiguous reference to the resource within a given context DOI: Source A related resource from which the described resource is derived Sport Mont Publisher An entity responsible for making the resource available Montenegrin Sports Academy and Faculty for Sport and Physical Education Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Sports Language A language of the resource EN https://www.socictopen.socict.org/files/original/fc1e33c1b43b33e784156e2727a99b1a.pdf 29c7e5fbd607c003f3227783753d1c11 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource An Investigation of Viral Agents in Patients Presenting with Flu-Like Symptoms Creator An entity primarily responsible for making the resource Gurdal Yilmaz, Kemalettin AYDIN, Rahmet ÇAYLAN, Ebru Emel SÖZEN, Gönülden AKTOZ BOZ, Iftihar Koksal Description An account of the resource Flu, is an infectious disease caused by influenza viruses. Various different viruses, such as respiratory syncytial virus (RSV), parainfluenza virus, adenovirus, rhinovirus and coronavirus constitute infection with flulike symptoms. In our study, the patients who applied to our hospital with flu-like symptoms and clinical findings between October 2001 to April 2002 and October 2003 to April 2004 were evaluated. Viral antigens and antibodies in the nasopharyngeal aspirates and serum samples were investigated by immunofluorescent technique. In our study we determined etiological agents in 48.6% of 37 patients evaluated in the period I, and in 44% of 25 patients in the period II. In the first period, influenza B was determined as 61.1%, influenza A as 22.2% and RSV as 16.7%, while in the second period influenza A was determined as 45.5%, RSV as 27.3%, influenza B as 18.2% and parainfluenza type 1 as 9.1%. The most frequently encountered symptoms in patients were fatigue, fever, sweating, headache and muscle pain, coughing, running eyes, and sound and taste changes. Duration of symptoms was 6.8 ± 3.1 days in the group in which the etiological agent was identified and 4.6 ± 2.4 days in the group in which the etiological agent could not be determined. Our findings show that the dominant influenza virus type varies from year to year. Immunofluorescence, a rapid, reliable and simple test, is important in the identification of viral agents. However, agent identification becomes difficult in situations in which disease symptoms and viremia are not obvious and are short-lived. Agent identification and good clinical observation prevent inappropriate antibiotherapy aimed at bacterial infections in patients presenting with flu-like symptoms. Date A point or period of time associated with an event in the lifecycle of the resource 2007 Subject The topic of the resource Human flu, influenza, Influenza A virus, Immunofluorescence technique Identifier An unambiguous reference to the resource within a given context DOI: Source A related resource from which the described resource is derived Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi Publisher An entity responsible for making the resource available Bilimsel Tip Yayinevi Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Microbiology Language A language of the resource EN, TR