2065 10 20655 https://www.socictopen.socict.org/files/original/57c7ef65dd81f4a951e1e79f2ac19064.pdf bb6bdaf776122399665d0751d70dfe0f Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource پیامدهای مادری و نوزادی زنان باردار با تشخیص کووید-19 در بیمارستان امیرالمومنین از اسفند 1398 لغایت اردیبهشت 1399 Creator An entity primarily responsible for making the resource منصوره معیا, دکتر شاداب شاه علی, دکتر بهنام فرهودی Description An account of the resource مقدمه: بیماری کووید-19 نوعی بیماری نوظهور عفونی است. در دوران شیوع بیماری‌های عفونی، زنان باردار و جنین آنها جمعیتی پرخطر را تشکیل می‌دهند. مطالعه حاضر با هدف بررسی پیامدهای مادری و نوزادی زنان باردار مبتلا به کووید-19 در بیمارستان امیرالمومنین تهران انجام شد. روش‌کار: در این مطالعه توصیفی case-series تمامی زنان باردار مراجعه‌کننده جهت زایمان به بیمارستان امیرالمومنین تهران که علائم مشکوک به کووید-19 را داشتند، طی اسفند 1398 لغایت انتهای اردیبهشت 1399 بررسی شدند. افراد تحت نمونه‌برداری قرار گرفته و عوارض مادری و نوزادی مادران تشخیص داده شده با تظاهرات بالینی و یا آزمایشگاهی مورد بررسی قرار گرفت. تجزیه و تحلیل داده‌ها با استفاده از نرم‌افزار آماری SPSS (نسخه 21) و روش‌های آمار توصیفی (میانگین، انحراف معیار، تعداد و درصد) انجام شد. یافته‌ها: شایع‌ترین علامت بیماری در 7 زن (100% مورد بررسی، تب بود. تنها 2 زن (57/28%) به اکسیژن نازال بعد از زایمان نیاز پیدا کردند و هیچ‌کدام از زنان باردار نیاز به دستگاه‌های تنفسی کمکی پیدا نکرد. تمام بیماران CRP بالا و درگیری ریوی در سی‌تی اسکن ریه داشتند. 5 نوزاد به شیوه طبیعی به‌دنیا آمدند، 1 نوزاد پره‌ترم و 1 نوزاد با وزن کمتر از 2500 گرم متولد شدند، یک نوزاد پسر دچار اسفیکسی شد، 1 مرگ نوزاد پسر 5 ساعت بعد از تولد مشاهده شد و 2 نوزاد بعد از تولد با علائم کووید 19 بستری شدند، اگرچه تست PCR هر دو منفی گزارش شد. نتیجه‌گیری: با توجه به نتایج مطالعه حاضر، کووید 19 با عوارض مادری و نوزادی همراه است. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource SARS-CoV-2, کووید-19, بارداری, پیامدهای مادری, کرونا ویروس 2019 Identifier An unambiguous reference to the resource within a given context 10.22038/ijogi.2020.17373 Source A related resource from which the described resource is derived Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān Publisher An entity responsible for making the resource available Mashhad University of Medical Sciences Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Gynecology and obstetrics https://www.socictopen.socict.org/files/original/582d445af916bbc62f01b8b3a84e4cae.pdf f8f9c7966f21a63ab90bcb6bffddd079 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource فعالیت ورزشی، سیستم ایمنی و کروناویروس Creator An entity primarily responsible for making the resource مهدیه ملانوری شمسی, صادق امانی Description An account of the resource سندروم حاد تنفسی جدید یعنی کروناویروس-دو (SARS-CoV2)، ایجادکنندة بیماری کووید 19 (COVID-19) به‌عنوان یک بیماری همه‌گیر تهدیدکنندة جوامع بشری از جنبه­های متفاوت است. به‌نظر می­رسد درحال‌حاضر، راهبرد اصلی مدیریت کروناویروس پیشگیری از ابتلا به آن است. فعالیت­های ورزشی با شدت متوسط علاوه‌بر ارتقای آمادگی جسمانی، باعث تقویت پاسخ­های سیستم ایمنی سلولی و هومورال به‌ویژه در افراد با ضعف سیستم ایمنی درمعرض خطر عوارض کروناویروس مانند افراد مسن، افراد چاق و دارای بیماری­های مزمن می­‌شوند؛ بنابراین، انجام‌دادن فعالیت­های ورزشی به‌صورت منظم در طول عمر می‌تواند راهبردی مؤثر برای پیشگیری از بیماری ویروسی مانند کووید-19 باشد. ازطرفی، قرنطینة خانگی و استفاده‌نکردن از اماکن ورزشی عمومی باعث کاهش میزان آمادگی جسمانی، اختلال در ریتم شبانه‌روزی، اختلال در خواب، افسردگی، افزایش رفتارهای بی‌تحرکانه و برهم‌خوردن تعادل انرژی دریافتی و مصرفی می­شوند که تمامی این موارد با ضعف سیستم ایمنی و خطر عوارض شدیدتر حاصل از بیماری کووید 19 همراه‌اند. فعالیت بدنی با شدت متوسط در خانه در زمان شیوع این بیماری می­تواند راهبردی مؤثر در مقابله با این عوارض ­باشد. همچنین، فعالیت بدنی با شدت متوسط به‌صورت مستقیم از طریق تقویت سیستم ایمنی، ارتقای دفاع آنتی‌اکسیدانتی و تقویت پاسخ­های ضدالتهابی و نیز به‌صورت غیرمستقیم از طریق کاهش اضطراب، بهبود خلق‌‌وخو، تعدیل نیم‌رخ چربی و حساسیت انسولینی، در ارتقای سیستم ایمنی و مقابله با عوارض کروناویروس مؤثر است. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource فعالیت هوازی, لکوسیت, بیماری کووید-19, ورزش در خانه, عفونت مجاری فوقانی تنفسی, عفونت ویروسی Identifier An unambiguous reference to the resource within a given context 10.22089/spj.2020.9033.2038 Source A related resource from which the described resource is derived فیزیولوژی ورزشی Publisher An entity responsible for making the resource available Sport Sciences Research Institute Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Sports medicine, Sports https://www.socictopen.socict.org/files/original/0f6fadb335c4300a1a7de52ff2163554.pdf 85d6f81c98b3ff7e56e3c96d0b6ea6c6 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Contact Transmission of COVID-19 in South Korea: Novel Investigation Techniques for Tracing Contacts Description An account of the resource In the epidemiological investigation of an infectious disease, investigating, classifying, tracking, and managing contacts by identifying the patient’s route are important for preventing further transmission of the disease. However, omissions and errors in previous activities can occur when the investigation is performed through only a proxy interview with the patient. To overcome these limitations, methods that can objectively verify the patient’s claims (medical facility records, Global Positioning System, card transactions, and closed-circuit television) were used for the recent ongoing coronavirus disease 2019 contact investigations in South Korea. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Contact Tracing, Global Positioning System, infectious disease, MEDICAL RECORDS, 2019 novel coronavirus infection Identifier An unambiguous reference to the resource within a given context DOI: 10.24171/j.phrp.2020.11.1.09 Source A related resource from which the described resource is derived Osong Public Health and Research Perspectives Publisher An entity responsible for making the resource available Korea Centers for Disease Control & Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Special situations and conditions Language A language of the resource EN https://www.socictopen.socict.org/files/original/96a9cc87f1aa9c783228cd9ae42edba5.pdf d49f3af333412745222ef86ae3c397db Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Early Epidemiological and Clinical Characteristics of 28 Cases of Coronavirus Disease in South Korea Description An account of the resource Objectives The first confirmed case of coronavirus disease 2019 (COVID-19) in South Korea was reported in January 2020, with 28 confirmed cases reported as of February 14th, 2020. The epidemiological and clinical characteristics of all 28 cases were analyzed in response to this disease. Methods The epidemiological characteristics and early clinical features of the 28 patients from Korea with confirmed COVID-19 were analyzed using COVID-19 reporting and surveillance data and the epidemiological investigation reports prepared by the rapid response team. Results There were 16 patients that entered Korea from foreign countries: Wuhan, China (11 patients), Zhuhai, China, (1 patient), Singapore (2 patients), Japan (1 patient), and Thailand (1 patient). The early symptoms were fever, sore throat, cough or sputum production, chills, and muscle ache. Three patients were asymptomatic, however, 18 developed pneumonia. Of the 28 cases, 16 were index cases imported from abroad, with 10 cases of secondary infection originating in Korea, and the route of transmission still under investigation for 2 patients. The 10 patients with secondary infection were infected from contact with family members or acquaintances of primary patients, and the suspected sites of transmission were mostly at home. Conclusion COVID-19 in Korea was spread by 16 infected individuals traveling from other countries, leading to second-generation cases. The initial symptoms were mostly minor, but the disease was infectious at this stage, resulting from close contact, particularly at home. Establishing an early detection strategy for COVID-19 is crucial for managing the transmission of the disease. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource COVID-19, epidemiologic study, SARS-CoV-2 Identifier An unambiguous reference to the resource within a given context DOI: 10.24171/j.phrp.2020.11.1.03 Source A related resource from which the described resource is derived Osong Public Health and Research Perspectives Publisher An entity responsible for making the resource available Korea Centers for Disease Control & Prevention Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases, Special situations and conditions Language A language of the resource EN https://www.socictopen.socict.org/files/original/12c869c80f8e630336d1f4219174d1fd.pdf 9f77e6830ebf4e5fdb8f93fe0bec9928 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Croup is associated with the novel coronavirus NL63. Description An account of the resource BACKGROUND: The clinical relevance of infections with the novel human coronavirus NL63 (HCoV-NL63) has not been investigated systematically. We therefore determined its association with disease in young children with lower respiratory tract infection (LRTI). METHODS AND FINDINGS: Nine hundred forty-nine samples of nasopharyngeal secretions from children under 3 y of age with LRTIs were analysed by a quantitative HCoV-NL63-specific real-time PCR. The samples had been collected from hospitalised patients and outpatients from December 1999 to October 2001 in four different regions in Germany as part of the prospective population-based PRI.DE study and analysed for RNA from respiratory viruses. Forty-nine samples (5.2%), mainly derived from the winter season, were positive for HCoV-NL63 RNA. The viral RNA was more prevalent in samples from outpatients (7.9%) than from hospitalised patients (3.2%, p = 0.003), and co-infection with either respiratory syncytial virus or parainfluenza virus 3 was observed frequently. Samples in which only HCoV-NL63 RNA could be detected had a significantly higher viral load than samples containing additional respiratory viruses (median 2.1 x 10(6) versus 2.7 x 10(2) copies/ml, p = 0.0006). A strong association with croup was apparent: 43% of the HCoV-NL63-positive patients with high HCoV-NL63 load and absence of co-infection suffered from croup, compared to 6% in the HCoV-NL63-negative group, p < 0.0001. A significantly higher fraction (17.4%) of samples from croup patients than from non-croup patients (4.2%) contained HCoV-NL63 RNA. CONCLUSION: HCoV-NL63 infections occur frequently in young children with LRTI and show a strong association with croup, suggesting a causal relationship. Date A point or period of time associated with an event in the lifecycle of the resource 2005 Identifier An unambiguous reference to the resource within a given context DOI: Source A related resource from which the described resource is derived PLoS Medicine Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/74e2a4ef3e23046424e4bc89ebe06f9d.pdf 76dd367748bd511522c1d6c025b8ab06 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Functional and Genetic Analysis of Coronavirus Replicase-Transcriptase Proteins. Description An account of the resource The coronavirus replicase-transcriptase complex is an assembly of viral and cellular proteins that mediate the synthesis of genome and subgenome-sized mRNAs in the virus-infected cell. Here, we report a genetic and functional analysis of 19 temperature-sensitive (ts) mutants of Murine hepatitis virus MHV-A59 that are unable to synthesize viral RNA when the infection is initiated and maintained at the non-permissive temperature. Both classical and biochemical complementation analysis leads us to predict that the majority of MHV-A59 ORF1a replicase gene products (non-structural proteins nsp1-nsp11) form a single complementation group (cistron1) while the replicase gene products encoded in ORF1b (non-structural proteins nsp12-nsp16) are able to function in trans and comprise at least three, and possibly five, further complementation groups (cistrons II-VI). Also, we have identified mutations in the non-structural proteins nsp 4, nsp5, nsp10, nsp12, nsp14, and nsp16 that are responsible for the ts phenotype of eight MHV-A59 mutants, which allows us to conclude that these proteins are essential for the assembly of a functional replicase-transcriptase complex. Finally, our analysis of viral RNA synthesis in ts mutant virus-infected cells allows us to discriminate three phenotypes with regard to the inability of specific mutants to synthesize viral RNA at the non-permissive temperature. Mutant LA ts6 appeared to be defective in continuing negative-strand synthesis, mutant Alb ts16 appeared to form negative strands but these were not utilized for positive-strand RNA synthesis, and mutant Alb ts22 was defective in the elongation of both positive- and negative-strand RNA. On the basis of these results, we propose a model that describes a pathway for viral RNA synthesis in MHV-A59-infected cells. Further biochemical analysis of these mutants should allow us to identify intermediates in this pathway and elucidate the precise function(s) of the viral replicase proteins involved. Date A point or period of time associated with an event in the lifecycle of the resource 2005 Identifier An unambiguous reference to the resource within a given context DOI: Source A related resource from which the described resource is derived PLoS Pathogens Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General), Immunologic diseases. Allergy Language A language of the resource EN https://www.socictopen.socict.org/files/original/3cc1acc572bef78de33c709a376298b0.pdf c5514b0bc36ad6f5ac85abe2d7d18e48 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Time Course and Cellular Localization of SARS-CoV Nucleoprotein and RNA in Lungs from Fatal Cases of SARS. Description An account of the resource BACKGROUND: Cellular localization of severe acute respiratory syndrome coronavirus (SARS-CoV) in the lungs of patients with SARS is important in confirming the etiological association of the virus with disease as well as in understanding the pathogenesis of the disease. To our knowledge, there have been no comprehensive studies investigating viral infection at the cellular level in humans. METHODS AND FINDINGS: We collected the largest series of fatal cases of SARS with autopsy material to date by merging the pathological material from two regions involved in the 2003 worldwide SARS outbreak in Hong Kong, China, and Toronto, Canada. We developed a monoclonal antibody against the SARS-CoV nucleoprotein and used it together with in situ hybridization (ISH) to analyze the autopsy lung tissues of 32 patients with SARS from Hong Kong and Toronto. We compared the results of these assays with the pulmonary pathologies and the clinical course of illness for each patient. SARS-CoV nucleoprotein and RNA were detected by immunohistochemistry and ISH, respectively, primarily in alveolar pneumocytes and, less frequently, in macrophages. Such localization was detected in four of the seven patients who died within two weeks of illness onset, and in none of the 25 patients who died later than two weeks after symptom onset. CONCLUSIONS: The pulmonary alveolar epithelium is the chief target of SARS-CoV, with macrophages infected subsequently. Viral replication appears to be limited to the first two weeks after symptom onset, with little evidence of continued widespread replication after this period. If antiviral therapy is considered for future treatment, it should be focused on this two-week period of acute clinical disease. Date A point or period of time associated with an event in the lifecycle of the resource 2006 Identifier An unambiguous reference to the resource within a given context DOI: Source A related resource from which the described resource is derived PLoS Medicine Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine Language A language of the resource EN https://www.socictopen.socict.org/files/original/ae4ff2801aa5937b6aadf175ec08a1e6.pdf 76dd367748bd511522c1d6c025b8ab06 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Functional and Genetic Analysis of Coronavirus Replicase-Transcriptase Proteins. Description An account of the resource The coronavirus replicase-transcriptase complex is an assembly of viral and cellular proteins that mediate the synthesis of genome and subgenome-sized mRNAs in the virus-infected cell. Here, we report a genetic and functional analysis of 19 temperature-sensitive (ts) mutants of Murine hepatitis virus MHV-A59 that are unable to synthesize viral RNA when the infection is initiated and maintained at the non-permissive temperature. Both classical and biochemical complementation analysis leads us to predict that the majority of MHV-A59 ORF1a replicase gene products (non-structural proteins nsp1-nsp11) form a single complementation group (cistron1) while the replicase gene products encoded in ORF1b (non-structural proteins nsp12-nsp16) are able to function in trans and comprise at least three, and possibly five, further complementation groups (cistrons II-VI). Also, we have identified mutations in the non-structural proteins nsp 4, nsp5, nsp10, nsp12, nsp14, and nsp16 that are responsible for the ts phenotype of eight MHV-A59 mutants, which allows us to conclude that these proteins are essential for the assembly of a functional replicase-transcriptase complex. Finally, our analysis of viral RNA synthesis in ts mutant virus-infected cells allows us to discriminate three phenotypes with regard to the inability of specific mutants to synthesize viral RNA at the non-permissive temperature. Mutant LA ts6 appeared to be defective in continuing negative-strand synthesis, mutant Alb ts16 appeared to form negative strands but these were not utilized for positive-strand RNA synthesis, and mutant Alb ts22 was defective in the elongation of both positive- and negative-strand RNA. On the basis of these results, we propose a model that describes a pathway for viral RNA synthesis in MHV-A59-infected cells. Further biochemical analysis of these mutants should allow us to identify intermediates in this pathway and elucidate the precise function(s) of the viral replicase proteins involved. Date A point or period of time associated with an event in the lifecycle of the resource 2005 Identifier An unambiguous reference to the resource within a given context DOI: Source A related resource from which the described resource is derived PLoS Pathogens Publisher An entity responsible for making the resource available Public Library of Science (PLoS) Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Biology (General), Immunologic diseases. Allergy Language A language of the resource EN https://www.socictopen.socict.org/files/original/3472bba5b985d5cac954a65d29fc05f9.pdf 6fd25befc1b7660d96ce483e360b7a10 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Guía para preparar a los servicios locales de salud ante la aparición de casos de síndrome respiratorio agudo grave (SARS) Preparatory guidelines for local health services on how to respond to new cases of severe acute respiratory syndrome (SARS) Description An account of the resource The Centers for Disease Control and Prevention (CDC) of the United States of America recently issued a set of guidelines on how different community health services should prepare for and respond to the reemergence of severe acute respiratory syndrome (SARS). This document summarizes the recommendations of the CDC for basic health services. Disease surveillance in communities and hospitals should be performed in light of existing information on risk factors, particularly those related to geographic dissemination patterns and to documented transmission of SARS-CoV, the coronavirus that causes SARS. As long as no cases of person-to-person disease transmission are reported anywhere in the world, efforts should be aimed at early detection and notification of cases and of groups of people who are in contact with one another and who have severe respiratory infections of undetermined cause, such as pneumonia, which could signal the reemergence of SARS. If cases of transmission of SARS-CoV have been reported, the aim should be to immediately identify and notify any cases detected in order to take appropriate diagnostic and therapeutic measures and to facilitate outbreak control. The reach of surveillance and reporting activities in specific communities should depend on how widely the disease has spread, both in the community and in local health services. Physicians and public health workers should be familiar with ways to detect SARS cases early, as well as with existing norms for reporting any cases detected. Date A point or period of time associated with an event in the lifecycle of the resource 2004 Subject The topic of the resource SARS, síndrome respiratorio agudo grave Identifier An unambiguous reference to the resource within a given context DOI: Source A related resource from which the described resource is derived Revista Panamericana de Salud Pública Publisher An entity responsible for making the resource available Pan American Health Organization Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Arctic medicine. Tropical medicine, Public aspects of medicine, Medicine https://www.socictopen.socict.org/files/original/5218e3eff8513f87cc36c5578f2439e5.pdf 16d637c0a5c6628738bfbf3ee644a57a Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Management of Critically Ill Patients with Severe Acute Respiratory Syndrome (SARS) Description An account of the resource Severe acute respiratory syndrome (SARS) is frequently complicated with acute respiratory failure. In this article, we aim to focus on the management of the subgroup of SARS patients who are critically ill. Most SARS patients would require high flow oxygen supplementation, 20–30% required intensive care unit (ICU) or high dependency care, and 13–26% developed acute respiratory distress syndrome (ARDS). In some of these patients, the clinical course can progress relentlessly to septic shock and/or multiple organ dysfunction syndrome (MODS). The management of critically ill SARS patients requires timely institution of pharmacotherapy where applicable and supportive treatment (oxygen therapy, noninvasive and invasive ventilation). Superimposed bacterial and other opportunistic infections are common, especially in those treated with mechanical ventilation. Subcutaneous emphysema, pneumothoraces and pneumomediastinum may arise spontaneously or as a result of positive ventilatory assistance. Older age is a consistently a poor prognostic factor. Appropriate use of personal protection equipment and adherence to infection control measures is mandatory for effective infection control. Much of the knowledge about the clinical aspects of SARS is based on retrospective observational data and randomized-controlled trials are required for confirmation. Physicians and scientists all over the world should collaborate to study this condition which may potentially threaten human existence. Date A point or period of time associated with an event in the lifecycle of the resource 2004 Subject The topic of the resource Management, Critically ill patients, severe acute respiratory syndrome, SARS, Treatment and control Identifier An unambiguous reference to the resource within a given context DOI: Source A related resource from which the described resource is derived International Journal of Medical Sciences Publisher An entity responsible for making the resource available Ivyspring International Publisher Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine