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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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                <text>Pharmacological Therapy for COVID-19: Where Are We Now and Where Are We Going?</text>
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                <text>Baha Eldin Hassan Juma, Alya Salah Babiker Higazy, Mohamed H Ahmed</text>
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                <text>Background: Up to the point of writing this review, there is no scientific evidence of any effective medical therapy for coronavirus disease 2019 (COVID-19). In this review, we attempted to discuss the current summary of evidence of some medication, currently in trial for the treatment of COVID-19. Material and Methods: We have done an electronic literature search using the following database: PubMed, Medline, Scopus and Google scholar. These databases were searched using the keywords COVID-19 and pharmacological therapy. Results: At present, there are no well randomized controlled studies which can give evidence for most of the therapy used for COVID-19. Several medications are in trials for COVID-19, among them: 1/ chloroquine and hydroxychloroquine; 2/anti-virals oseltamivir, remdesivir, lopinavir/ritonavir and other protease inhibitors; 3/antibiotics macrolide (Azithromycin); 4/cytokine therapy interferon; 5/ humanized monoclonal antibody tocilizumab; 6/adjunct therapies vitamins C, D, and herbal medicine; 7/ COVID-19 convalescent plasma; 8/systemic steroids; 9/expected COVID-19 vaccine. We have also included some of the herbal medicines that are commonly and widely used in the Middle East, Asia as well in Sudan, (black seeds, honey and Acacia Nilotica). It is worth mentioning that these herbal medicines have shown benefits in treating other diseases, but the evidence of their benefit in COVID-19 still needs to be established. Conclusion: Currently there is no pharmacological therapy for the COVID-19. More research and randomized clinical trials are needed to find effective therapy or vaccine against COVID-19.</text>
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                <text>2020</text>
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                <text>Herbal Medicine, covid-19, pharmacotherapy, Sudan</text>
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            <name>Identifier</name>
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                <text>10.18502/sjms.v15i5.7014</text>
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            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
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                <text>Epidemiology and Health</text>
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                <text>Korean Society of Epidemiology</text>
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            <name>Coverage</name>
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                <text>Medicine</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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            <description>A name given to the resource</description>
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                <text>Excess Mortality During COVID-19 Pandemic in İstanbul.</text>
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                <text>Bahriye Oya İtil, Pınar Ay, Elif Dağlı, Seval Kul, Benan Müsellim, Filiz Çağla Uyanusta Küçük, Hasan Bayram</text>
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                <text>Epidemiological studies have shown that mortality owing to the coronavirus disease 2019 (COVID-19) could be under-reported under different conditions. Excess mortality analysis is suggested as a useful tool in estimating the impact of the disease. Mortality data between January 01 and May 18, 2020, were analyzed to evaluate the excess mortality owing to COVID-19 in Istanbul, the city most affected by the pandemic in Turkey. The average weekly percentage changes in the number of deaths in 4 previous years were compared with those in the year 2020 using excess mortality analysis. The number of deaths in Istanbul was significantly higher in 2020 (p=0.001), with a 10% weekly increase between the 10th and 15th weeks, which started to decrease until the 20th week. The excess mortality found during the study period was 4,084 deaths, higher than the officially reported COVID-19 mortality. Our findings demonstrated that mortality owing to COVID-19 could be higher than the official figures reported by health authorities.</text>
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                <text>2021</text>
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                <text>10.5152/TurkThoracJ.2021.20258</text>
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            <description>A related resource from which the described resource is derived</description>
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                <text>Turkish thoracic journal</text>
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              <name>Title</name>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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            <description>A name given to the resource</description>
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                <text>Genomic Evolution and Variation of SARS-CoV-2 in the Early Phase of COVID-19 Pandemic in Guangdong Province, China.</text>
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                <text>Bai-Sheng Li, Zhen-Cui Li, Yao Hu, Li-Jun Liang, Li-Rong Zou, Qian-Fang Guo, Zhong-Hua Zheng, Jian-Xiang Yu, Tie Song, Jie Wu</text>
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                <text>Severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) with unknown origin spread rapidly to 222 countries, areas or territories. To investigate the genomic evolution and variation in the early phase of COVID-19 pandemic in Guangdong, 60 specimens of SARS-CoV-2 were used to perform whole genome sequencing, and genomics, amino acid variation and Spike protein structure modeling analyses. Phylogenetic analysis suggested that the early variation in the SARS-CoV-2 genome was still intra-species, with no evolution to other coronaviruses. There were one to seven nucleotide variations (SNVs) in each genome and all SNVs were distributed in various fragments of the genome. The Spike protein bound with human receptor, an amino acid salt bridge and a potential furin cleavage site were found in the SARS-CoV-2 using molecular modeling. Our study clarified the characteristics of SARS-CoV-2 genomic evolution, variation and Spike protein structure in the early phase of local cases in Guangdong, which provided reference for generating prevention and control strategies and tracing the source of new outbreaks.</text>
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                <text>2021</text>
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                <text>spike protein, severe acute respiratory syndrome coronavirus 2 (sars-cov-2), genomic evolution</text>
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            <name>Identifier</name>
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              <elementText elementTextId="76246">
                <text>10.1007/s11596-021-2340-3</text>
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                <text>Current medical science</text>
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                  <text>Coronavirus</text>
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                  <text>Dominio científico: Coronavirus</text>
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            <name>Title</name>
            <description>A name given to the resource</description>
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                <text>Literatur review: Dukungan nutrisi untuk bayi yang lahir dari ibu dengan Covid-19</text>
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                <text>Bakhtiar Bakhtiar</text>
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            <name>Description</name>
            <description>An account of the resource</description>
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                <text>COVID-19 suffered by mothers who gave birth has an impact on newborns, including the risk of possible transmission. However, all the needs of newborns must remain a priority, especially regarding protection against possible transmission and nutritional needs, especially breast milk or formula milk. The care of the baby depends on the health condition or the wishes of the mother and family. In mothers with severe COVID-19, babies must be treated separately from their mothers. Conversely, if the mother is asymptomatic, the baby can be treated together, but still according to health protocols. Two impacts on the baby are related to breastfeeding are the risk of transmission and the effects of drugs taken by the mother that can be transmitted through breast milk. There are three ways to provide nutrition for the newborn, depending on the severity of the COVID-19 that the mother is suffering from. If without symptoms, breastfeeding is direct. If symptoms are mild, breastfeeding is indirect. Meanwhile, if COVID-19 with severe symptoms, the baby is only given donor breast milk or formula milk. Provision of advanced nutrition, after treatment, is complete, the baby is still given breast milk from the mother and stops donor breast milk or formula milk.</text>
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                <text>2020</text>
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                <text>newborn, Nutritional support, mother with covid-19</text>
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                <text>10.30867/action.v5i2.398</text>
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                <text>AcTion: Aceh Nutrition Journal</text>
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                <text>Jurusan Gizi Politeknik Kesehatan Kemenkes Aceh</text>
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            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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                <text>Nutrition. Foods and food supply, Food processing and manufacture</text>
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                  <text>Agricultura sostenible</text>
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              <description>An account of the resource</description>
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                  <text>Dominio científico: Agricultura sostenible</text>
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                <text>UNA REVISIÓN DEL COMPLEJO LOPHIARIS CAVENDISHIANA (ORCHIDACEAE: ONCIDIINAE)</text>
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                <text>Balam Ricardo, Cetzal William</text>
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                <text>El complejo Lophiaris cavendishiana está conformado por L. bicallosa, L. cavendishiana, L. chrysops y L. pachyphylla. Estas especies se caracterizan principalmente por las flores grandes (30,0-45,0 mm diámetro) y amarillas y por su distribución restringida a las cadenas montañosas del centro y sur de México y norte de Centroamérica (a elevaciones de entre 800 y 2800 m), usualmente asociadas a bosques mesófilos, bosques de pino encino y bosques perennifolios nublados. Sin embargo, las especies son semejantes en su morfología vegetativa y floral, por tal razón, la circunscripción específica y los límites de distribución geográfica de cada una es aún confuso, principalmente de L. cavendishiana y L. pachyphylla. El objetivo de esta contribución es entender la variación morfológica de estas cuatro especies para esclarecer sus identidades y definir sus límites de distribución geográfica. Se presenta una revisión taxonómica, la cual incluye una clave para reconocer las especies, un mapa de distribución, actualizaciones nomenclaturales, descripciones, caracteres diagnósticos, distribución y ecología, comentarios taxonómicos, material citado y estados de conservación basados en los criterios UICN y MER. Los principales caracteres morfológicos para distinguir a las especies del complejo fueron el tamaño y la forma de los lóbulos laterales del labelo, longitud y ancho del lóbulo central del labelo, y así como la forma, la posición y el número de los dientes del callo del labelo.</text>
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                <text>Two highly human pathogenic coronaviruses outbreak in the beginning of 21st century i.e. Severe AcuteRespiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome Coronavirus(MERS-CoV) in 2002 and 2012 respectively caused high pathogenicity and fatality rates in humanpopulations. Recently, a new coronavirus named as SARS-CoV-2 or nCoV-2019 was first reportedin Wuhan, China in December 2019 which is responsible for an acute human respiratory illnessreferred as Coronavirus Disease (COVID-19), an ongoing pandemic. SARS-CoV-2 is the third knownhighly pathogenic virus affecting human population. This virus spread globally within few weeks offirst identification and nearly 5.52 million confirmed cases with more than 3,47,000 deaths reportedas of May 25, 2020. Till date, there are no specific anti-viral drugs, therapies or vaccines to containand prevent this infectious pathogen outbreak. The global spread of this virus to over 210 countriesresulted in both human and economic losses, highlighting the need for an immediate imperativeresearch exploration on prophylactic and therapeutic measures. Current knowledge and understandingof the pathogenesis of similar coronavirus SARS-CoV and MERS-CoV might be helpful for the rapiddevelopment of treatment strategies to prevent the further spread of this virus. In this review, werecapitulate the topical understanding on the structure, pathogenesis and epidemiology of SARS-CoV-2that has emerged as a major health concern worldwide.</text>
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                <text>Novel Coronavirus (2019-nCoV) is an emerging pathogen that was first identified in Wuhan, China in late December 2019. This virus is responsible for the ongoing outbreak that causes severe respiratory illness and pneumonia-like infection in humans. Due to the increasing number of cases in China and outside China, the WHO declared coronavirus as a global health emergency. Nearly 35,000 cases were reported and at least 24 other countries or territories have reported coronavirus cases as early on as February. Inter-human transmission was reported in a few countries, including the United States. Neither an effective anti-viral nor a vaccine is currently available to treat this infection. As the virus is a newly emerging pathogen, many questions remain unanswered regarding the virus&amp;#8217;s reservoirs, pathogenesis, transmissibility, and much more is unknown. The collaborative efforts of researchers are needed to fill the knowledge gaps about this new virus, to develop the proper diagnostic tools, and effective treatment to combat this infection. Recent advancements in plant biotechnology proved that plants have the ability to produce vaccines or biopharmaceuticals rapidly in a short time. In this review, the outbreak of 2019-nCoV in China, the need for rapid vaccine development, and the potential of a plant system for biopharmaceutical development are discussed.</text>
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                <text>The reported cases of MERS Cov in Arabian Peninsula and sporadic caseselsewhere except in sub Saharan Africa at present is disquieting considering itsinitial clinical feature that mimic flu like symptoms caused by other viruses.However MERS Cov is associated with organ dysfunction and high mortality.Although the mode of transmission is still unclear, it is postulated that itspreads through close contact, possibly via respiratory route. High similaritiesof MERS CoV carried by humans and camels may suggest that the diseases arezoonotic. Furthermore, airborne nosocomial transmission can occur in theroom shared by the patients in the hospitals. There is still the confusion oftransmission through body fluids or clinical samples, including stools and across transmission with medical devices or hands. Currently, all known casescan be directly or indirectly linked to Middle East from where it derives its name. Cases reported outside the Middle East first developed infection in the Middle East and then were exported outside the region. Several hospital-acquired outbreaks that resulted in upsurge of MERS Cov cases in Jeddah revealed lack of systematic implementation of infection prevention and control measures to effectively control emerging infectious diseases. The causative agent is detected and identified using Enzyme Linked Immuunosorbent Assay (ELISA) and real-time polymerase chain reaction (RT-PCR) that is expensive and not readily available in hospitals located in resource poor settings such as sub Saharan Africa. Although, so far no case of MERS Cov has been reported from sub Saharan Africa, the devastating consequences of MERS epidemic will be more catastrophic if it emerges in developing nations especially in sub Saharan Africa where there are no up to date facilities for investigations and management of such cases. Against this backdrop, we review this hazardous and incurable disease believing that it would create the necessary awareness among stakeholders to prepare for ‘alien’diseases like MERS Cov.Pilgrims all over the world visit Saudi Arabia for religious obligation (Hajj). This is a potential way this virus could be transmitted across the globe within a short span especially if an epidemic occurs during or towards the end of the hajj exercise.</text>
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              <name>Title</name>
              <description>A name given to the resource</description>
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                  <text>Coronavirus</text>
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              <name>Description</name>
              <description>An account of the resource</description>
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                  <text>Dominio científico: Coronavirus</text>
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      <name>Text</name>
      <description>A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.</description>
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        <name>Dublin Core</name>
        <description>The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.</description>
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          <element elementId="50">
            <name>Title</name>
            <description>A name given to the resource</description>
            <elementTextContainer>
              <elementText elementTextId="60789">
                <text>Mobility restrictions for the control of epidemics: When do they work?</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="39">
            <name>Creator</name>
            <description>An entity primarily responsible for making the resource</description>
            <elementTextContainer>
              <elementText elementTextId="60790">
                <text>Baltazar Espinoza, Carlos Castillo-Chavez, Charles Perrings</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="41">
            <name>Description</name>
            <description>An account of the resource</description>
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              <elementText elementTextId="60791">
                <text>BackgroundMobility restrictions-trade and travel bans, border closures and, in extreme cases, area quarantines or cordons sanitaires-are among the most widely used measures to control infectious diseases. Restrictions of this kind were important in the response to epidemics of SARS (2003), H1N1 influenza (2009), Ebola (2014) and, currently in the containment of the ongoing COVID-19 pandemic. However, they do not always work as expected.MethodsTo determine when mobility restrictions reduce the size of an epidemic, we use a model of disease transmission within and between economically heterogeneous locally connected communities. One community comprises a low-risk, low-density population with access to effective medical resources. The other comprises a high-risk, high-density population without access to effective medical resources.FindingsUnrestricted mobility between the two risk communities increases the number of secondary cases in the low-risk community but reduces the overall epidemic size. By contrast, the imposition of a cordon sanitaire around the high-risk community reduces the number of secondary infections in the low-risk community but increases the overall epidemic size.InterpretationMobility restrictions may not be an effective policy for controlling the spread of an infectious disease if it is assessed by the overall final epidemic size. Patterns of mobility established through the independent mobility and trade decisions of people in both communities may be sufficient to contain epidemics.</text>
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            <name>Date</name>
            <description>A point or period of time associated with an event in the lifecycle of the resource</description>
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                <text>2020</text>
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          <element elementId="43">
            <name>Identifier</name>
            <description>An unambiguous reference to the resource within a given context</description>
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              <elementText elementTextId="60793">
                <text>10.1371/journal.pone.0235731</text>
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          <element elementId="48">
            <name>Source</name>
            <description>A related resource from which the described resource is derived</description>
            <elementTextContainer>
              <elementText elementTextId="60794">
                <text>Epidemiology and Health</text>
              </elementText>
            </elementTextContainer>
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          <element elementId="45">
            <name>Publisher</name>
            <description>An entity responsible for making the resource available</description>
            <elementTextContainer>
              <elementText elementTextId="60795">
                <text>Korean Society of Epidemiology</text>
              </elementText>
            </elementTextContainer>
          </element>
          <element elementId="38">
            <name>Coverage</name>
            <description>The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant</description>
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              <elementText elementTextId="60796">
                <text>Science, Medicine</text>
              </elementText>
            </elementTextContainer>
          </element>
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