236 10 20655 https://www.socictopen.socict.org/files/original/0d3b82e665d8dda6bda38e1475574df9.pdf bd39c1bf68046f3ae2c74c49e3bd3df1 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Detection of Recombinant Rousettus Bat Coronavirus GCCDC1 in Lesser Dawn Bats (<i>Eonycteris spelaea</i>) in Singapore Creator An entity primarily responsible for making the resource Lin-Fa Wang, Theron Hamilton, Kenneth G. Frey, Regina Z. Cer, Kimberly A. Bishop-Lilly, Ian H. Mendenhall, Danielle E. Anderson, Eric D. Laing, Casandra W. Philipson, Matthew R. Lueder, Kyle A. Long, Gregory K. Rice, Wan Ni Chia, Xiao Fang Lim, Justin H. J. Ng, Adrian C. Paskey, Randy J. H. Foo, Gavin J. Smith Description An account of the resource Rousettus bat coronavirus GCCDC1 (RoBat-CoV GCCDC1) is a cross-family recombinant coronavirus that has previously only been reported in wild-caught bats in Yúnnan, China. We report the persistence of a related strain in a captive colony of lesser dawn bats captured in Singapore. Genomic evidence of the virus was detected using targeted enrichment sequencing, and further investigated using deeper, unbiased high throughput sequencing. RoBat-CoV GCCDC1 Singapore shared 96.52% similarity with RoBat-CoV GCCDC1 356 (NC_030886) at the nucleotide level, and had a high prevalence in the captive bat colony. It was detected at five out of six sampling time points across the course of 18 months. A partial segment 1 from an ancestral Pteropine orthoreovirus, p10, makes up the recombinant portion of the virus, which shares high similarity with previously reported RoBat-CoV GCCDC1 strains that were detected in Yúnnan, China. RoBat-CoV GCCDC1 is an intriguing, cross-family recombinant virus, with a geographical range that expands farther than was previously known. The discovery of RoBat-CoV GCCDC1 in Singapore indicates that this recombinant coronavirus exists in a broad geographical range, and can persist in bat colonies long-term. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource coronavirus, Recombinant, lesser dawn bat, Rousettus bat coronavirus GCCDC1 Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/v12050539 Source A related resource from which the described resource is derived Viruses Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology https://www.socictopen.socict.org/files/original/823601e8e1b963950903323a6c86b69a.pdf 5580665d1c41cd825b9fadadcdc4d1a5 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A Novel Synonymous Mutation of Sars-Cov-2: Is This Possible to Affect Their Antigenicity and Immunogenicity? Creator An entity primarily responsible for making the resource Yong-Ho Park, Sung Jae Kim, Van Giap Nguyen, Bongkyun Park, Hee-Chun Chung Description An account of the resource The S glycoprotein of coronaviruses is important for viral entry and pathogenesis with most variable sequences. Therefore, we analyzed the S gene sequences of SARS-CoV-2 to better understand the antigenicity and immunogenicity of this virus in this study. In phylogenetic analysis, two subtypes (SARS-CoV-2a and -b) were confirmed within SARS-CoV-2 strains. These two subtypes were divided by a novel synonymous mutation of D614G. This may play a crucial role in the evolution of SARS-CoV-2 to evade the host immune system. The region containing this mutation point was confirmed as a B-cell epitope located in the S1 domain, and SARS-CoV-2b strains exhibited severe reduced antigenic indexes compared to SARS-CoV-2a in this area. This may allow these two subtypes to have different antigenicity. If the two subtypes have different serological characteristics, a vaccine for both subtypes will be more effective to prevent COVID-19. Thus, further study is urgently required to confirm the antigenicity of these two subtypes. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource spike protein, antigenicity, SARS-CoV-2, COVID-19 Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/vaccines8020220 Source A related resource from which the described resource is derived Vaccines Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/923a406bd2a53be5488e924a30c5e139.pdf 41a8b49b166503e6ade993ab4b8c7ff5 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Rapid Antibody-based Tests for the Diagnosis of COVID-19: A Bigger Epidemic of Unscientific Practices Creator An entity primarily responsible for making the resource Sarman Singh Date A point or period of time associated with an event in the lifecycle of the resource 2020 Identifier An unambiguous reference to the resource within a given context DOI: 10.1055/s-0040-1712711 Source A related resource from which the described resource is derived Journal of Laboratory Physicians Publisher An entity responsible for making the resource available Wolters Kluwer Medknow Publications Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/3fe54d269a4caa0598f578d928b6fc4c.pdf 32598c47290d1f168a3926d103831d16 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Effects of the COVID-19 Lockdown on Urban Mobility: Empirical Evidence from the City of Santander (Spain) Creator An entity primarily responsible for making the resource Andrés Rodríguez, Felipe González, Borja Alonso, Juan Benavente, Rubén Cordera, Roberto Sañudo, Eneko Echaniz, Alfredo Aloi, Claudio Ladisa, Raquel Lezama-Romanelli, Álvaro López-Parra, Vittorio Mazzei, Lucía Perrucci, Darío Prieto-Quintana Description An account of the resource This article analyses the impact that the confinement measures or quarantine imposed in Spain on 15 March 2020 had on urban mobility in the northern city of Santander. Data have been collected from traffic counters, public transport ITS, and recordings from traffic control cameras and environmental sensors to make comparisons between journey flows and times before and during the confinement. This data has been used to re-estimate Origin-Destination trip matrices to obtain an initial diagnostic of how daily mobility has been reduced and how the modal distribution and journey purposes have changed. The impact on externalities such as NO2 emissions and traffic accidents have also been quantified. The analysis revealed an overall mobility fall of 76%, being less important in the case of the private car. Public transport users dropped by up to 93%, NO2 emissions were reduced by up to 60%, and traffic accidents were reduced by up to 67% in relative terms. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource mobility, traffic, coronavirus, confinement, quarantine, COVID-19 Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/su12093870 Source A related resource from which the described resource is derived Sustainability Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Environmental sciences, Renewable energy sources, Environmental effects of industries and plants https://www.socictopen.socict.org/files/original/65e9f78cc3a2c7851c90b58489295966.pdf a2037a8bd0b3515ae72164a65fdce4e7 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Genetic alteration, RNA expression, and DNA methylation profiling of coronavirus disease 2019 (COVID-19) receptor ACE2 in malignancies: a pan-cancer analysis Creator An entity primarily responsible for making the resource Jie Yu, Xianqun Fan, Shengfang Ge, Renbing Jia, Peiwei Chai Description An account of the resource Abstract The novel coronavirus (2019-nCoV) is an emerging causative agent that was first described in late December 2019 and causes a severe respiratory infection in humans. Notably, many of affected patients of COVID-19 were people with malignancies. Moreover, cancer has been identified as an individual risk factor for COVID-19. In addition, the expression of angiotensin converting enzyme 2 (ACE2), the receptor of COVID-19, were aberrantly expressed in many tumors. However, a systematic analysis of ACE2 aberration remained to be elucidated in human cancers. Here, we analyzed genetic alteration, RNA expression, and DNA methylation of ACE2 across over 30 tumors. Notably, overexpression of ACE2 have been observed in including colon adenocarcinoma (COAD), kidney renal papillary cell carcinoma (KIRP), pancreatic adenocarcinoma (PAAD), rectum adenocarcinoma (READ), stomach adenocarcinoma (STAD), and lung adenocarcinoma (LUAD). In addition, hypo DNA methylation of ACE2 has also been identified in most of these ACE2 highly expressed tumors. Conclusively, our study for the first time curated both genetic and epigenetic variations of ACE2 in human malignancies. Notably, because our study is a bioinformatics assay, further functional and clinical validation is warranted. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource expression, ACE2, COVID-19 Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s13045-020-00883-5 Source A related resource from which the described resource is derived Journal of Hematology & Oncology Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Diseases of the blood and blood-forming organs https://www.socictopen.socict.org/files/original/6683a815f25d81d7815c13af44ebeed2.pdf 56e5241db4cffc66471bd1dc84bff686 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource A child with household transmitted COVID-19 Creator An entity primarily responsible for making the resource Jian Xu, Dan Zhang, Peng Zhao, Bin Li, Jian-Wei Pan, Zhihao Xu, Xiao-Ping Xia, Yuehong Wang, Jian-Guo He, Yue Su, Lijuan Mao, Zhe-Feng YUAN Description An account of the resource Abstract Background Although people of all ages are susceptible to the novel coronavirus infection, which is presently named “Coronavirus Disease 2019” (COVID-19), there has been relatively few cases reported among children. Therefore, it is necessary to understand the clinical characteristics of COVID-19 in children and the differences from adults. Case presentation We report one pediatric case of COVID-19. A 14-month-old boy was admitted to the hospital with a symptom of fever, and was diagnosed with a mild form of COVID-19. The child’s mother and grandmother also tested positive for SARS-CoV-2 RNA. However, the lymphocyte counts were normal. The chest computed tomography (CT) revealed scattered ground glass opacities in the right lower lobe close to the pleura and resorption after the treatment. The patient continued to test positive for SARS-CoV-2 RNA in the nasopharyngeal swabs and stool at 17 days after the disappearance of symptoms. Conclusion The present pediatric case of COVID-19 was acquired through household transmission, and the symptoms were mild. Lymphocyte counts did not significantly decrease. The RNA of SARS-CoV-2 in stool and nasopharyngeal swabs remained positive for an extended period of time after the disappearance of symptoms. This suggests that attention should be given to the potential contagiousness of pediatric COVID-19 cases after clinical recovery. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Children, SARS-CoV-2, COVID-19 Identifier An unambiguous reference to the resource within a given context DOI: 10.1186/s12879-020-05056-w Source A related resource from which the described resource is derived BMC Infectious Diseases Publisher An entity responsible for making the resource available BMC Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Infectious and parasitic diseases https://www.socictopen.socict.org/files/original/50dfd636070474f2b41eada91dfadbdf.pdf 70629d7cbeb17e35c372ec2c02d37cb3 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Review of Evidence Available on Hesperidin-Rich Products as Potential Tools against COVID-19 and Hydrodynamic Cavitation-Based Extraction as a Method of Increasing Their Production Creator An entity primarily responsible for making the resource Rosaria Ciriminna, Francesco Meneguzzo, Mario Pagliaro, Federica Zabini Description An account of the resource Based on recent computational and experimental studies, hesperidin, a bioactive flavonoid abundant in citrus peel, stands out for its high binding affinity to the main cellular receptors of SARS-CoV-2, outperforming drugs already recommended for clinical trials. Thus, it is very promising for prophylaxis and treatment of COVID-19, along with other coexistent flavonoids such as naringin, which could help restraining the proinflammatory overreaction of the immune system. Controlled hydrodynamic cavitation processes showed the highest speed, effectiveness and efficiency in the integral and green aqueous extraction of flavonoids, essential oils and pectin from citrus peel waste. After freeze-drying, the extracted pectin showed high quality and excellent antioxidant and antibacterial activities, attributed to flavonoids and essential oils adsorbed and concentrated on its surface. This study reviews the recent evidence about hesperidin as a promising molecule, and proposes a feasible and affordable process based on hydrodynamic cavitation for the integral aqueous extraction of citrus peel waste resulting in hesperidin-rich products, either aqueous extracts or pectin tablets. The uptake of this process on a relevant scale is urged, in order to achieve large-scale production and distribution of hesperidin-rich products. Meanwhile, experimental and clinical studies could determine the effective doses either for therapeutic and preventive purposes. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource Hesperidin, Flavonoids, coronavirus, Hesperetin, citrus fruits, COVID-19 Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/pr8050549 Source A related resource from which the described resource is derived Processes Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Chemistry, Chemical technology https://www.socictopen.socict.org/files/original/0d51bfce0a116e9a616c6d03831c899d.pdf daa5f6f1797debd72f9488c4a3538c52 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Influenza Virus Like Particles (VLPs): Opportunities for H7N9 Vaccine Development Creator An entity primarily responsible for making the resource Peter Pushko, Irina Tretyakova Description An account of the resource In the midst of the ongoing COVID-19 coronavirus pandemic, influenza virus remains a major threat to public health due to its potential to cause epidemics and pandemics with significant human mortality. Cases of H7N9 human infections emerged in eastern China in 2013 and immediately raised pandemic concerns as historically, pandemics were caused by the introduction of new subtypes into immunologically naïve human populations. Highly pathogenic H7N9 cases with severe disease were reported recently, indicating the continuing public health threat and the need for a prophylactic vaccine. Here we review the development of recombinant influenza virus-like particles (VLPs) as vaccines against H7N9 virus. Several approaches to vaccine development are reviewed including the expression of VLPs in mammalian, plant and insect cell expression systems. Although considerable progress has been achieved, including demonstration of safety and immunogenicity of H7N9 VLPs in the human clinical trials, the remaining challenges need to be addressed. These challenges include improvements to the manufacturing processes, as well as enhancements to immunogenicity in order to elicit protective immunity to multiple variants and subtypes of influenza virus. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource H7N9, avian flu, Pandemic Influenza A, IAV, vlp vaccine Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/v12050518 Source A related resource from which the described resource is derived Viruses Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Microbiology https://www.socictopen.socict.org/files/original/11acf69658fab74cbecb1d26602469f2.pdf d829d70e58093be0491c8a958b47bbd7 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource What Caused the Outbreak of COVID-19 in China: From the Perspective of Crisis Management Creator An entity primarily responsible for making the resource Wen Sun, Mark Yaolin Wang, Ziheng Shangguan Description An account of the resource Since the first known case of a COVID-19 infected patient in Wuhan, China on 8 December 2019, COVID-19 has spread to more than 200 countries, causing a worldwide public health crisis. The existing literature fails to examine what caused this sudden outbreak from a crisis management perspective. This article attempts to fill this research gap through analysis of big data, officially released information and other social media sources to understand the root cause of the crisis as it relates to China’s current management system and public health policy. The article draws the following conclusions: firstly, strict government control over information was the main reason for the early silencing of media announcements, which directly caused most people to be unprepared and unaware of COVID-19. Secondly, a choice between addressing a virus with an unknown magnitude and nature, and mitigating known public panic during a politically and culturally sensitive time, lead to falsehood and concealment. Thirdly, the weak autonomous management power of local public health management departments is not conducive for providing a timely response to the crisis. Finally, the privatization of many state-owned hospitals led to the unavailability of public health medical resources to serve affected patients in the Wuhan and Hubei Province. This article suggests that China should adopt a Singaporean-style public health crisis information management system to ensure information disclosure and information symmetry and should use it to monitor public health crises in real time. In addition, the central government should adopt the territorial administration model of a public health crisis and increase investment in public health in China. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource China, Public Health, big data, crisis management, COVID-19 Identifier An unambiguous reference to the resource within a given context DOI: 10.3390/ijerph17093279 Source A related resource from which the described resource is derived International Journal of Environmental Research and Public Health Publisher An entity responsible for making the resource available MDPI AG Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Medicine https://www.socictopen.socict.org/files/original/04eb1258829fa7bef4615a2843022a00.pdf e9d060f1b3bbc9d68586b975dd5cc00c Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Lesión por presión relacionada a un dispositivo médico en los profesionales de la salud en época de pandemia Creator An entity primarily responsible for making the resource Paula de Souza Silva Freitas, Paula Cristina Nogueira, Aline Oliveira Ramalho Description An account of the resource Ante el número de casos de infección por el coronavirus (COVID-19), la Organización Mundial de la Salud (OMS) declaró que la enfermedad se trata de una pandemia de alarma y movilización mundial, estando presente en varios países y continentes. En Brasil, la pandemia llegó a finales de febrero del 2020 y está causando alarma por el aumento en el número de contaminados relacionado con la alta capacidad de transmisión de la enfermedad. En los enfermos afectados el virus puede causar desde síntomas simples, que pueden ser tratados en casa, hasta ingresos hospitalarios, asistencia en unidades de terapia intensiva y puede incluso llevar a la muerte. Date A point or period of time associated with an event in the lifecycle of the resource 2020 Subject The topic of the resource - Identifier An unambiguous reference to the resource within a given context DOI: 10.30886/estima.v18.867_ESP Source A related resource from which the described resource is derived Estima Publisher An entity responsible for making the resource available Associação Brasileira de Estomaterapia Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Nursing